Research – University of Copenhagen

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Research at BRIC

Disease-oriented basic research is the main focus of the research at BRIC. Our overall aim is to contribute to a basic understanding of how and why disease occurs, to discover new disease-related genes, and to identify new diagnostic markers, which are essential to provide more efficient treatment. From 2011, BRIC has entered into a scientific collaboration with the Finsen Laboratory, Rigshospitalet, to coordinate our cancer research projects. We currently have 23 research groups working on research projects relevant for cancer, neurological and metabolic diseases. Click on the group name below if you wish to know more about their research:

Andersen Group
Tumor heterogeneity
Translational genomics
Single cell genomics

Bioinformatics Group

miRNA, ancient DNA,
disease transcriptomics, gene regulation

Behrendt Group
Cancer invasion, metastasis, degredation of extracellular matrix, collagen endocytosis


Brakebusch Group
Rho GTPases, mouse models, cancer, inflammation

Couchman Group 
Cell adhesion, receptors, signaling, cytoskeleton, syndecan 

Engelholm Group
Cancer invasion, UPAR, MMPs, proteases, extracellular matrix degradtion
Erler Group
Hypoxia and metastasis, lysyl oxidases, tissue stiffness, network medicine
  Frödin Group
Protein kinase signal transduction, cancer biology, epigenetics, metastasis models 

Groth Group 
Chromatin replication, epigenetics, genome stability 

  Hansen Group
Signaling to chromatin, epigenetics, stem cells, cancer

Helin Group
Epigenetics, stem cells, cancer biology
Høyer-Hansen Group
Pericellular proteolysis, monoclonal antibodies, immuno-assays, cancer biomakers, experimental therapy

Issazadeh-Navikas Group
Glioblastoma,neuroinflammation  neurodegeneration, neuron-T cell signaling, neuroimmunolog

  Jensen Group
Somatic stem cells, cancer stem cells 

Kveiborg Group 
ADAM metalloproteases, integrins, protein trafficking, cell signaling and cancer 

Linding Group
Cell Signaling, Biological Forecasting, Tumor-specific Treatment Strategies, Cancer Evolution, Phosphorylation Networks

Lund Group 
Non-coding RNA,
epigenetics, cancer models

Ploug Group
Protein structure and function at cancer invasion, metastasis, extracellular matrix degradation

Pocock Group Neurobiology, microRNAs, stress


Porse Group  Hematopoietic/cancer stem cells, leukemia, nonsense-mediated mRNA decay

Salcini Group 
C. elegans development, chromatin, histone methylation

Sørensen Group 
Genome maintenance, chromatin, DNA damage response 

Theilgaard-Mönch Group Acute myeloid leukemia (AML), Molecular mechanisms of hematopoietic development