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Research at BRIC

Disease-oriented basic research is the main focus of the research at BRIC. Our overall aim is to contribute to a basic understanding of how and why disease occurs, to discover new disease-related genes, and to identify new diagnostic markers, which are essential to provide more efficient treatment. From 2011, BRIC has entered into a scientific collaboration with the Finsen Laboratory, Rigshospitalet, to coordinate our cancer research projects.  We currently have 19 research groups working on research projects relevant for  cancer, neurological and metabolic diseases. Click on the group name below if you wish to know more about their research:

Bioinformatics Group
miRNA, ancient DNA,
disease transcriptomics, gene regulation
  Behrendt Group
Cancer invasion, metastasis, degredation of extracellular matrix, collagen endocytosis
  Brakebusch Group
Rho GTPases, mouse models, cancer, inflammation 
    Couchman Group 
Cell adhesion, receptors, signaling, cytoskeleton, syndecan 
Engelholm Group
Cancer invasion, UPAR, MMPs, proteases, extracellular matrix degradtion
  Erler Group
Hypoxia and metastasis, lysyl oxidases, tissue stiffness, network medicine
Frödin Group
Protein kinase signal transduction, cancer biology, epigenetics, metastasis models 
    Groth Group 
Chromatin replication, epigenetics, genome stability 
Hansen Group
Signaling to chromatin, epigenetics, stem cells, cancer
    Helin Group
Epigenetics, stem cells, cancer biology
  Høyer-Hansen Group
Experimental treatment, proteolysis, immuno-assays, biomakers, monoclonal antibodies 
    Issazadeh-Navikas Group
Glioblastoma, neuroinflammation  neurodegeneration, neuron-T cell signaling, neuroimmunology 
Jensen Group
Somatic stem cells, cancer stem cells 
  Lund Group 
Non-coding RNA,
epigenetics, cancer models
Ploug Group
Protein structure and function at cancer invasion, metastasis, extracellular matrix degradation
  Pocock Group
Neurobiology, microRNAs,
stress
Porse Group 
Hematopoietic/cancer stem cells, leukemia, nonsense-mediated mRNA decay
  Salcini Group 
C. elegans development, chromatin, histone methylation
Sørensen Group 
Genome maintenance, chromatin, DNA damage response 
Wewer Group 
ADAM metalloproteases, integrins, cellular interactions and migration, signaling, cancer