Research at BRIC
Disease-oriented basic research is the main focus of the research at BRIC. Our overall aim is to contribute to a basic understanding of how and why disease occurs, to discover new disease-related genes, and to identify new diagnostic markers, which are essential to provide more efficient treatment. Since 2011, BRIC has collaborated with the Finsen Laboratory, Rigshospitalet, to coordinate our cancer research projects. We currently have 23 research groups working on research projects relevant for cancer, neurological and metabolic diseases. Click on the group name below if you wish to know more about their research:
Tumor heterogeneity, Translational genomics, Single cell genomics
Cancer invasion, metastasis, degradation of extracellular matrix
Cell adhesion, receptors, signaling, cytoskeleton, syndecan
Hypoxia and metastasis, lysyl oxidases, tissue stiffness, network medicin
Chromatin replication, epigenetics, genome stability
Epigenetics, stem cells,
Somatic stem cells
Cancer stem cells
ADAM metalloproteases, integrins, protein trafficking, cell signaling, cancer
epigenetics, cancer models
C. elegans development, chromatin, histone methylation
Acute myeloid leukemia (AML), Molecular mechanisms of hematopoietic development
miRNA, ancient DNA, disease transcriptomics, gene regulation
Rho GTPases, mouse models, cancer, inflammation
Cancer invasion, UPAR, MMPs, extracellular matrix degradation
Protein kinase signal transduction, cancer biology, epigenetics, metastasis models
Signaling to chromatin, epigenetics, stem cells, cancer
Glioblastoma, neuroinflammation neurodegeneration.
brain development, neuronal differentiation, transcriptional programs
Cell Signaling, Biological Forecasting, Tumor-specific Treatment Strategies.
Protein structure and function at cancer invasion, metastasis.
Hematopoietic/cancer stem cells, leukemia.
Genome maintenance, chromatin, DNA damage response
Cancer genomics, structural variants, prostate cancer, precision medicine, bioinformatics