Research – University of Copenhagen

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Research at BRIC

Disease-oriented basic research is the main focus of the research at BRIC. Our overall aim is to contribute to a basic understanding of how and why disease occurs, to discover new disease-related genes, and to identify new diagnostic markers, which are essential to provide more efficient treatment. From 2011, BRIC has entered into a scientific collaboration with the Finsen Laboratory, Rigshospitalet, to coordinate our cancer research projects. We currently have 22 research groups working on research projects relevant for cancer, neurological and metabolic diseases. Click on the group name below if you wish to know more about their research:

Andersen Group
Tumor heterogeneity
Translational genomics
Single cell genomics

Bioinformatics Group

miRNA, ancient DNA,
disease transcriptomics, gene regulation

 

Behrendt Group
Cancer invasion, metastasis, degredation of extracellular matrix, collagen endocytosis

 

Brakebusch Group
Rho GTPases, mouse models, cancer, inflammation


Couchman Group 
Cell adhesion, receptors, signaling, cytoskeleton, syndecan 

 
Engelholm Group
Cancer invasion, UPAR, MMPs, proteases, extracellular matrix degradtion
Erler Group
Hypoxia and metastasis, lysyl oxidases, tissue stiffness, network medicine
  Frödin Group
Protein kinase signal transduction, cancer biology, epigenetics, metastasis models 

Groth Group 
Chromatin replication, epigenetics, genome stability 

  Hansen Group
Signaling to chromatin, epigenetics, stem cells, cancer


Helin Group
Epigenetics, stem cells, cancer biology
 
Høyer-Hansen Group
Pericellular proteolysis, monoclonal antibodies, immuno-assays, cancer biomakers, experimental therapy

Issazadeh-Navikas Group
Glioblastoma,neuroinflammation  neurodegeneration, neuron-T cell signaling, neuroimmunolog

  Jensen Group
Somatic stem cells, cancer stem cells 

Linding Group

Lund Group 
Non-coding RNA,
epigenetics, cancer models
 
Ploug Group
Protein structure and function at cancer invasion, metastasis, extracellular matrix degradation
   

Pocock Group Neurobiology, microRNAs, stress

Porse Group 
Hematopoietic/cancer stem cells, leukemia, nonsense-mediated mRNA decay

    Salcini Group 
C. elegans development, chromatin, histone methylation
 
Sørensen Group 
Genome maintenance, chromatin, DNA damage response 
   

Theilgaard-Mönch Group Acute myeloid leukemia (AML), Molecular mechanisms of hematopoietic development.


Wewer Group 
ADAM metalloproteases, integrins, cellular interactions and migration, signaling, cancer