Screening Instrumentation

 

 

Assay readout

Manufacturer: GE Healthcare Life Sciences

Capabilities: Fast, sensitive, and flexible automated cell imaging using 4x, 10x, 20x and 40x objectives and filters for imaging DAPI, FITC, Cy3, TxRed, Cy5, CFP and YFP; non-confocal but with advanced 3D deconvolution software

Applications: Broad range of high-content assays, 2D and 3D

Plate format: slide to 384-well


IN Cell Analyzer 2200




 

 

Assay readout

Manufacturer: Molecular Devices

Capabilities: Fast, sensitive and flexible automated cell imaging using 4x, 10x, 20x (optional water immersion) or 40x (water immersion) objectives  and filters for imaging DAPI, CFP, FITC, YFP, TRITC, Cy5, Cy7 and TexasRed. 60µm pinhole confocality available and image analysis softwares, MetaXpress® and IN Carta®.

Applications: Broad range of high-content assays in 2D and 3D

Plate format: Mainly 96- and 384 well

 

 

 

Assay readout

Manufacturer: BioTek

Capabilities: Flexible and sensitive plate reader with monochromator based absorbance and filter based fluorescence/luminescence

Applications: 2D and 3D Broad range of absorbance or lumiscent based biological readouts; DNA measurement

Plate format: 96- and 384-well

Synergy HTX Multi-Mode Reader





 

 

Assay readout

Manufacturer: PerkinElmer

Capabilities:  Plate reader with ultra-sensitive luminescence and filter-based absorbance technology, fluorescence well-imaging with single cell resolution as well as brightfield and digital phase-contrast imaging.

Application: 2D and 3D Broad range of absorbance or luminescent based biological readouts; DNA measurement

Plate format: 96- and 384-well

 

 

 

Assay readout

Manufacturer: ESSEN BIOSCIENCE

Capabilities: Real-time, non-invasive, quantitative live-cell analysis; 4x and 10x objectives, HD phase-contrast, FITC, Cy3 and TxRed

Applications: Proliferation, wound-healing, scratch assays

Plate format: Flask, dish, slides and plate formats from 24 to 384-well

IncuCyte® Live-Cell Analysis System





 

 

 

 

 

 

Liquid Handling

Manufacturer: Hamilton

Capabilities: Liquid transfer using disposable pipet tips (Hamilton); 384well head; plate handling

Applications: HT 384well transfections/treatments; HT- QPCR; library handling

Plate format: 384-well

Transfer volume: 2-50µl

Microlab STARlet





 

 

 

 

 

Liquid Handling

Manufacturer:Labcyte

Capabilities: Liquid transfer using ultrasonic acoustic energy (tips-free); flexible low-volume transfer for HT formats

Applications: compound screens, dose-response curves, antibody staining, library cherry-pick, low-volume qPCR

Plate format: 96- and 384-well

Transfer volume: Echo 550: 2.5nl- 2µl; Echo 525: 25nl- 5 µl

See more about The Echo Acoustic Liquid Handling Technology

 

 

Liquid Handling

Manufacturer: BioTek

Capabilities: Liquid dispensing using random access dispense (RAD) and multi-mode dispensing

Applications: cell seeding, reagent dispensing

Plate format: 6- and 1536-well

Transfer volume: 20-30,000 µl/well

 

 

Liquid Handling

Manufacturer: BioTek

Capabilities: Microplate washing

Applications: Washing of fixed as well as live cells

Plate format: 96- and 384-well

Transfer volume: 50 µl- 3,000 µl/well