Cord Herbert Brakebusch

Cord Herbert Brakebusch


  1. 2024
  2. Published

    Rac1 promotes kidney collecting duct repair by mechanically coupling cell morphology to mitotic entry

    Bock, F., Dong, X., Li, S., Viquez, O. M., Sha, E., Tantengco, M., Hennen, E. M., Plosa, E., Ramezani, A., Brown, K. L., Whang, Y. M., Terker, A. S., Arroyo, J. P., Harrison, D. G., Fogo, A., Brakebusch, Cord Herbert, Pozzi, A. & Zent, R., 2024, In: Science Advances. 10, 6, eadi7840.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2023
  4. Published

    A RhoA-mediated biomechanical response in Schwann cells modulates peripheral nerve myelination

    Seixas, A. I., Morais, M. R. G., Brakebusch, Cord Herbert & Relvas, J. B., 2023, In: Progress in Neurobiology. 227, 13 p., 102481.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Epithelial RAC1-dependent cytoskeleton dynamics controls cell mechanics, cell shedding and barrier integrity in intestinal inflammation

    Martínez-Sánchez, L. D. C., Ngo, P. A., Pradhan, R., Becker, L-S., Boehringer, D., Soteriou, D., Kubankova, M., Schweitzer, C., Koch, T., Thonn, V., Erkert, L., Stolzer, I., Günther, C., Becker, C., Weigmann, B., Klewer, M., Daniel, C., Amann, K., Tenzer, S., Atreya, R. & 8 others, Bergo, M., Brakebusch, Cord Herbert, Watson, A. J. M., Guck, J., Fabry, B., Atreya, I., Neurath, M. F. & López-Posadas, R., 2023, In: Gut. 72, 2, p. 275-294 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Microglial Rac1 is essential for experience-dependent brain plasticity and cognitive performance

    Socodato, R., Almeida, T. O., Portugal, C. C., Santos, E. C. S., Tedim-Moreira, J., Galvão-Ferreira, J., Canedo, T., Baptista, F. I., Magalhães, A., Ambrósio, A. F., Brakebusch, Cord Herbert, Rubinstein, B., Moreira, I. S., Summavielle, T., Pinto, I. M. & Relvas, J. B., 2023, In: Cell Reports. 42, 12, 28 p., 113447.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    RhoB promotes Salmonella survival by regulating autophagy

    Kirchenwitz, M., Halfen, J., von Peinen, K., Prettin, S., Kollasser, J., zur Lage, S., Blankenfeldt, W., Brakebusch, Cord Herbert, Rottner, K., Steffen, A. & Stradal, T. E. B., 2023, In: European Journal of Cell Biology. 102, 4, 17 p., 151358.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    RhoB promotesSalmonellasurvival by regulating autophagy

    Kirchenwitz, M., Halfen, J., Peinen, K. V., Prettin, S., Kollasser, J., Brakebusch, Cord Herbert, Rottner, K., Steffen, A. & Stradal, T. E. B., 2023, bioRxiv, 52 p.

    Research output: Working paperPreprintResearch

  9. Published

    Two Transient Receptor Potential Channels at Focal Adhesions

    Mitsou, I., Carlson, C. R., Multhaupt, Hinke Arnolda B V H, Brakebusch, Cord Herbert & Couchman, John Robert, 2023, In: Journal of Histochemistry and Cytochemistry. 71, 9, p. 495-508 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2022
  11. Published

    Cardiac fibroblast sub-types in vitro reflect pathological cardiac remodeling in vivo

    Herum, K. M., Weng, Guangzheng, Kahnert, Konstantin, Waikel, R., Milburn, G., Conger, A., Anaya, P., Campbell, K. S., Lundby, Alicia, Won, K. J. & Brakebusch, Cord Herbert, 2022, In: Matrix Biology Plus. 15, 100113.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Characterization of TGF-β signaling in a human organotypic skin model reveals that loss of TGF-βRII induces invasive tissue growth

    Ye, Z., Kilic, G., Dabelsteen, Sally, Marinova, I. N., Thøfner, J. F. B., Song, Ming, Levann, Asha Maria Rudjord, Bagdonaite, Ieva , Vakhrushev, Sergey, Brakebusch, Cord Herbert, Olsen, Jesper Velgaard & Wandall, Hans H., 2022, In: Science Signaling. 15, 761, eabo2206.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Control of cortical cytoskeleton-membrane interaction by RhoA regulates peripheral nerve myelination

    Seixas, A. I., Morais, M. R. G., Brakebusch, Cord Herbert & Relvas, J. B., 2022, Cold Spring Harbor Laboratory, 15 p. (bioRxiv).

    Research output: Working paperPreprintResearch

  14. Published

    The Essential Role of Rac1 Glucosylation in Clostridioides difficile Toxin B-Induced Arrest of G1-S Transition

    Petersen, L., Stroh, S., Schöttelndreier, D., Grassl, G. A., Rottner, K., Brakebusch, Cord Herbert, Fahrer, J. & Genth, H., 2022, In: Frontiers in Microbiology. 13, 11 p., 846215.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    The Small GTPase RHOA Links SLP65 Activation to PTEN Function in Pre B Cells and Is Essential for the Generation and Survival of Normal and Malignant B Cells

    Vadakumchery, A., Faraidun, H., Ayoubi, O. E., Outaleb, I., Schmid, V., Abdelrasoul, H., Amendt, T., Khadour, A., Setz, C., Göhring, K., Lodd, K., Hitzing, C., Alkhatib, A., Bilal, M., Benckendorff, J., Al Shugri, A. K., Brakebusch, C. H., Engels, N., Datta, M., Hobeika, E. & 2 others, Alsadeq, A. & Jumaa, H., 2022, In: Frontiers in Immunology. 13, 19 p., 842340.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 2021
  17. Published

    ACK1 is dispensable for development, skin tumor formation, and breast cancer cell proliferation

    Brandao, R., Kwa, M. Q., Yarden, Y. & Brakebusch, Cord Herbert, 2021, In: FEBS Open Bio. 11, 6, p. 1579-1592 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    ATF3 downmodulates its new targets IFI6 and IFI27 to suppress the growth and migration of tongue squamous cell carcinoma cells

    Xu, L., Zu, T., Li, T., Li, M., Mi, J., Bai, F., Liu, G., Wen, J., Li, H., Brakebusch, Cord Herbert, Wang, X. & Wu, X., 2021, In: PLOS Genetics. 17, 2, p. 1-25 e1009283.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Analyzing skin tumor development in mice by the DMBA/TPA model

    Li, H. & Brakebusch, Cord Herbert, 2021, Carcinogen-driven mouse models of oncogenesis. Galluzzi, L. & Buqué, A. (eds.). Elsevier, Vol. 163. p. 113-121 9 p. (Methods in Cell Biology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  20. Published

    CRISPR Genome Editing: How to Make a Fantastic Method Even Better

    Brakebusch, Cord Herbert, 2021, In: Cells. 10, 2, p. 1-2 408.

    Research output: Contribution to journalEditorialResearchpeer-review

  21. Published

    MRCKα Is Dispensable for Breast Cancer Development in the MMTV-PyMT Model

    Kwa, M. Q., Brandao, R., Phung, T. H., Ge, J., Scieri, G. & Brakebusch, Cord Herbert, 2021, In: Cells. 10, 4, 942.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Rac1 promotes kidney collecting duct integrity by limiting actomyosin activity

    Bock, F., Elias, B. C., Dong, X., Parekh, D. V., Mernaugh, G., Viquez, O. M., Hassan, A., Amara, V. R., Liu, J., Brown, K. L., Terker, A. S., Chiusa, M., Gewin, L. S., Fogo, A. B., Brakebusch, Cord Herbert, Pozzi, A. & Zent, R., 2021, In: Journal of Cell Biology. 220, 11, 28 p., e202103080.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Rho GTPase Signaling in Health and Disease: A Complex Signaling Network

    Brakebusch, Cord Herbert, 2021, In: Cells. 10, 2, p. 1-3 401.

    Research output: Contribution to journalEditorialResearchpeer-review

  24. Published

    RhoA drives actin compaction to restrict axon regeneration and astrocyte reactivity after CNS injury

    Stern, S., Hilton, B. J., Burnside, E. R., Dupraz, S., Handley, E. E., Gonyer, J. M., Brakebusch, Cord Herbert & Bradke, F., 2021, In: Neuron. 109, 21, p. 3436-3455 30 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    RhoA/Cdc42 signaling drives cytoplasmic maturation but not endomitosis in megakaryocytes

    Heib, T., Hermanns, H. M., Manukjan, G., Englert, M., Kusch, C., Becker, I. C., Gerber, A., Wackerbarth, L. M., Burkard, P., Dandekar, T., Balkenhol, J., Jahn, D., Beck, S., Meub, M., Dütting, S., Stigloher, C., Sauer, M., Cherpokova, D., Schulze, H., Brakebusch, C. & 3 others, Nieswandt, B., Nagy, Z. & Pleines, I., 2021, In: Cell Reports. 35, 6, p. 109102 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. 2020
  27. Published

    Improving Precise CRISPR Genome Editing by Small Molecules: Is there a Magic Potion?

    Bischoff, N., Wimberger, S., Maresca, M. & Brakebusch, Cord Herbert, 2020, In: Cells. 9, 5

    Research output: Contribution to journalReviewResearchpeer-review

  28. Published

    Maintaining resting cardiac fibroblasts in vitro by disrupting mechanotransduction

    Gilles, G., McCulloch, A. D., Brakebusch, Cord Herbert & Herum, K. M., 2020, In: PLoS ONE. 15, 10, p. 1-13 e0241390.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Microglia Dysfunction Caused by the Loss of Rhoa Disrupts Neuronal Physiology and Leads to Neurodegeneration

    Socodato, R., Portugal, C. C., Canedo, T., Rodrigues, A., Almeida, T. O., Henriques, J. F., Vaz, S. H., Magalhães, J., Silva, C. M., Baptista, F. I., Alves, R. L., Coelho-Santos, V., Silva, A. P., Paes-de-Carvalho, R., Magalhães, A., Brakebusch, Cord Herbert, Sebastião, A. M., Summavielle, T., Ambrósio, A. F. & Relvas, J. B., 2020, In: Cell Reports. 31, 12, p. 1-29 107796.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    PATHBIO: an international training program for precision mouse phenotyping

    Ruberte, J., Schofield, P. N., Brakebusch, Cord Herbert, Vogel, P., Herault, Y., Gracia, G., McKerlie, C., Hrabĕ de Angelis, M., Hagn, M. & Sundberg, J. P., 2020, In: Mammalian Genome. 31, p. 49-53

    Research output: Contribution to journalJournal articleResearchpeer-review

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