Kristian Helin

Kristian Helin

professor, group leader


  1. 2021
  2. E-pub ahead of print

    Targeting RIOK2 ATPase activity leads to decreased protein synthesis and cell death in acute myeloid leukemia

    Messling, Jan-Erik, Agger, K., Andersen, Kasper Langebjerg, Kromer, K., Kuepper, H. M., Lund, Anders H. & Helin, Kristian, Jul 2021, (E-pub ahead of print) In: Blood.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    ChIP-Sequencing of TET Proteins

    Rasmussen, K. D. & Helin, Kristian, 2021, TET Proteins and DNA Demethylation. Springer, Vol. 2272. p. 251-262 12 p. (Methods in molecular biology (Clifton, N.J.), Vol. 2272).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  4. Published

    Complex-dependent histone acetyltransferase activity of KAT8 determines its role in transcription and cellular homeostasis

    Radzisheuskaya, A., Shliaha, P. V., Grinev, V. V., Shlyueva, Daria, Damhofer, H., Koche, R., Gorshkov, V., Kovalchuk, S., Zhan, Y., Rodriguez, K. L., Johnstone, A. L., Keogh, M. C., Hendrickson, R. C., Jensen, O. N. & Helin, Kristian, 2021, In: Molecular Cell. 81, 8, p. 1749-1765.e8

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Generation of locus-specific degradable tag knock-ins in mouse and human cell lines

    Damhofer, H., Radzisheuskaya, A. & Helin, Kristian, 2021, In: STAR Protocols. 2, 2, 100575.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    MPP8 is essential for sustaining self-renewal of ground-state pluripotent stem cells

    Müller, I., Moroni, Ann Sophie, Shlyueva, Daria, Sahadevan, S., Schoof, Erwin Marten, Radzisheuskaya, A., Højfeldt, J. W., Tatar, Tülin, Koche, R. P., Huang, C. & Helin, Kristian, 2021, In: Nature Communications. 12, 1, 3034.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    TET2 mutations are associated with hypermethylation at key regulatory enhancers in normal and malignant hematopoiesis

    Tulstrup, Morten Rytter, Soerensen, M., Hansen, Jakob Werner, Gillberg, Linn, Needhamsen, M., Kaastrup, K., Helin, Kristian, Christensen, K., Weischenfeldt, Joachim Lütken & Grønbæk, Kirsten, 2021, In: Nature Communications. 12, 1, 10 p., 6061.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. E-pub ahead of print

    compaRe, an ultra-fast and robust suite for multiparametric screening, identifies phenotypic drug responses in acute myeloid leukemia

    Chalabi Hajkarim, Morteza, Karjalainen, E., Osipovitch, Mikhail, Dimopoulos, K., Gordon, Sandra, Ambri, Francesca, Rasmussen, K. D., Grønbæk, Kirsten, Helin, Kristian, Wennerberg, Krister & Won, Kyoung Jae, 2021, (E-pub ahead of print) In: bioRxiv. 17 p.

    Research output: Contribution to journalJournal articleResearch

  9. 2020
  10. Published

    PR-DUB maintains expression of critical genes through FOXK1/2 and ASXL1/2/3-dependent recruitment to chromatin and H2AK119ub1 deubiquitination

    Kolovos, P., Nishimura, K., Sankar, Aditya, Sidoli, S., Cloos, Paul, Helin, Kristian & Christensen, J., Aug 2020, In: Genome Research. 30, 8, p. 1119-1130

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. BTK inhibitors synergize with 5-FU to treat drug-resistant TP53-null colon cancers

    Lavitrano, M., Ianzano, L., Bonomo, S., Cialdella, A., Cerrito, M. G., Pisano, F., Missaglia, C., Giovannoni, R., Romano, G., McLean, C. M., Voest, E. E., D'Amato, F., Noli, B., Ferri, G. L., Agostini, M., Pucciarelli, S., Helin, Kristian, Leone, B. E., Canzonieri, V. & Grassilli, E., Feb 2020, In: Journal of Pathology. 250, 2, p. 134-147 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Identification of recurrent FHL2-GLI2 oncogenic fusion in sclerosing stromal tumors of the ovary

    Kim, S. H., Da Cruz Paula, A., Basili, T., Dopeso, H., Bi, R., Pareja, F., da Silva, E. M., Gularte-Mérida, R., Sun, Z., Fujisawa, S., Smith, C. G., Ferrando, L., Martins Sebastião, A. P., Bykov, Y., Li, A., Silveira, C., Ashley, C. W., Stylianou, A., Selenica, P., Samore, W. R., Jungbluth, A. A., Zamarin, D., Abu-Rustum, N. R., Helin, Kristian, Soslow, R. A., Reis-Filho, J. S., Oliva, E. & Weigelt, B., 2 Jan 2020, In: Nature Communications. 11, 1, p. 44

    Research output: Contribution to journalJournal articleResearchpeer-review

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