Kyoung Jae Won
Kyoung Jae Won

Associate Professor

  • Won Group

    Ole Maaløes Vej 5, 2200 København N

    Phone: +45 35 33 14 19Mobile: +45 93 50 96 03

  1. 2019
  2. Published

    Genomic architecture of Shh-dependent cochlear morphogenesis

    Muthu, V., Rohacek, A. M., Yao, Y., Rakowiecki, S. M., Brown, A. S., Zhao, Y., Meyers, J., Won, Kyoung Jae, Ramdas, S., Brown, C. D., Peterson, K. A. & Epstein, D. J., 19 Sep 2019, In : Development (Cambridge, England). 146, 18, 12 p., 181339.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2018
  4. Published

    Shared nucleotide flanks confer transcriptional competency to bZip core motifs

    Cohen, D. M., Lim, H., Won, Kyoung Jae & Steger, D. J., 19 Sep 2018, In : Nucleic Acids Research. 46, 16, p. 8371-8384

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Distinct macrophage populations direct inflammatory versus physiological changes in adipose tissue

    Hill, D. A., Lim, H., Kim, Y. H., Ho, W. Y., Foong, Y. H., Nelson, V. L., Nguyen, H. C. B., Chegireddy, K., Kim, J., Habertheuer, A., Vallabhajosyula, P., Kambayashi, T., Won, Kyoung Jae & Lazar, M. A., 29 May 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 22, p. E5096-E5105

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Rev-erbα dynamically modulates chromatin looping to control circadian gene transcription

    Kim, Y. H., Marhon, S. A., Zhang, Y., Steger, D. J., Won, Kyoung Jae & Lazar, M. A., 16 Mar 2018, In : Science (New York, N.Y.). 359, 6381, p. 1274-1277 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Defiant: (DMRs: easy, fast, identification and ANnoTation) identifies differentially Methylated regions from iron-deficient rat hippocampus

    Condon, D. E., Tran, P. V., Lien, Y., Schug, J., Georgieff, M. K., Simmons, R. A. & Won, Kyoung Jae, 5 Feb 2018, In : BMC Bioinformatics. 19, 1, p. 31

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. PKCα-LSD1-NF-κB-Signaling Cascade Is Crucial for Epigenetic Control of the Inflammatory Response

    Kim, D., Nam, H. J., Lee, W., Yim, H. Y., Ahn, J., Park, S. W., Shin, H. R., Yu, R., Won, Kyoung Jae, Bae, J., Kim, K. I. & Baek, S. H., 1 Feb 2018, In : Molecular Cell. 69, 3, p. 398-411.e6

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Transcriptomic Analysis Reveals Novel Mechanisms Mediating Islet Dysfunction in the Intrauterine Growth-Restricted Rat

    Rashid, C. S., Lien, Y., Bansal, A., Jaeckle-Santos, L. J., Li, C., Won, Kyoung Jae & Simmons, R. A., 1 Feb 2018, In : Endocrinology. 159, 2, p. 1035-1049 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    CellBIC: bimodality-based top-down clustering of single-cell RNA sequencing data reveals hierarchical structure of the cell type

    Kim, Junil, Stanescu, D. E. & Won, Kyoung Jae, 2018, In : Nucleic Acids Research. 46, 21, p. 1-8 8 p., e124.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2017
  12. DNA hypermethylation induced by Epstein-Barr virus in the development of Epstein-Barr virus-associated gastric carcinoma

    Choi, S. J., Shin, Y. S., Kang, B. W., Kim, J. G., Won, Kyoung Jae, Lieberman, P. M., Cho, H. & Kang, H., Aug 2017, In : Archives of Pharmacal Research. 40, 8, p. 894-905 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  13. PRDM16 represses the type I interferon response in adipocytes to promote mitochondrial and thermogenic programing

    Kissig, M., Ishibashi, J., Harms, M. J., Lim, H., Stine, R. R., Won, Kyoung Jae & Seale, P., 1 Jun 2017, In : E M B O Journal. 36, 11, p. 1528-1542 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Targeting PPARγ in the epigenome rescues genetic metabolic defects in mice

    Soccio, R. E., Li, Z., Chen, E. R., Foong, Y. H., Benson, K. K., Dispirito, J. R., Mullican, S. E., Emmett, M. J., Briggs, E. R., Peed, L. C., Dzeng, R. K., Medina, C. J., Jolivert, J. F., Kissig, M., Rajapurkar, S. R., Damle, M., Lim, H., Won, Kyoung Jae, Seale, P., Steger, D. J. & Lazar, M. A., 3 Apr 2017, In : The Journal of Clinical Investigation. 127, 4, p. 1451-1462 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. EBF2 transcriptionally regulates brown adipogenesis via the histone reader DPF3 and the BAF chromatin remodeling complex

    Shapira, S. N., Lim, H., Rajakumari, S., Sakers, A. P., Ishibashi, J., Harms, M. J., Won, Kyoung Jae & Seale, P., 1 Apr 2017, In : Genes & Development. 31, 7, p. 660-673 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Single cell transcriptomic profiling of mouse pancreatic progenitors

    Stanescu, D. E., Yu, R., Won, Kyoung Jae & Stoffers, D. A., 1 Feb 2017, In : Physiological Genomics. 49, 2, p. 105-114 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. LIM domain-binding 1 maintains the terminally differentiated state of pancreatic β cells

    Ediger, B. N., Lim, H., Juliana, C., Groff, D. N., Williams, L. T., Dominguez, G., Liu, J., Taylor, B. L., Walp, E. R., Kameswaran, V., Yang, J., Liu, C., Hunter, C. S., Kaestner, K. H., Naji, A., Li, C., Sander, M., Stein, R., Sussel, L., Won, Kyoung Jae, May, C. L. & Stoffers, D. A., 3 Jan 2017, In : The Journal of Clinical Investigation. 127, 1, p. 215-229 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. 2016
  19. Epigenetic regulation of intestinal stem cells by Tet1-mediated DNA hydroxymethylation

    Kim, R., Sheaffer, K. L., Choi, I., Won, Kyoung Jae & Kaestner, K. H., 1 Nov 2016, In : Genes & Development. 30, 21, p. 2433-2442 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Single-Cell Transcriptomics of the Human Endocrine Pancreas

    Wang, Y. J., Schug, J., Won, Kyoung Jae, Liu, C., Naji, A., Avrahami, D., Golson, M. L. & Kaestner, K. H., Oct 2016, In : Diabetes. 65, 10, p. 3028-38 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Targeting ACLY sensitizes castration-resistant prostate cancer cells to AR antagonism by impinging on an ACLY-AMPK-AR feedback mechanism

    Shah, S., Carriveau, W. J., Li, J., Campbell, S. L., Kopinski, P. K., Lim, H., Daurio, N., Trefely, S., Won, Kyoung Jae, Wallace, D. C., Koumenis, C., Mancuso, A. & Wellen, K. E., 12 Jul 2016, In : OncoTarget. 7, 28, p. 43713-43730 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. AMPK-SKP2-CARM1 signalling cascade in transcriptional regulation of autophagy

    Shin, H. R., Kim, H., Oh, S., Lee, J., Kee, M., Ko, H., Kweon, M., Won, Kyoung Jae & Baek, S. H., 23 Jun 2016, In : Nature. 534, 7608, p. 553-7 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Threshold-Dependent Cooperativity of Pdx1 and Oc1 in Pancreatic Progenitors Establishes Competency for Endocrine Differentiation and β-Cell Function

    Henley, K. D., Stanescu, D. E., Kropp, P. A., Wright, C. V. E., Won, Kyoung Jae, Stoffers, D. A. & Gannon, M., 21 Jun 2016, In : Cell Reports. 15, 12, p. 2637-2650 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. The Nuclear Receptor Rev-erbα Regulates Adipose Tissue-specific FGF21 Signaling

    Jager, J., Wang, F., Fang, B., Lim, H., Peed, L. C., Steger, D. J., Won, Kyoung Jae, Kharitonenkov, A., Adams, A. C. & Lazar, M. A., 13 May 2016, In : The Journal of Biological Chemistry. 291, 20, p. 10867-75 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. The CSB chromatin remodeler and CTCF architectural protein cooperate in response to oxidative stress

    Lake, R. J., Boetefuer, E. L., Won, Kyoung Jae & Fan, H., 18 Mar 2016, In : Nucleic Acids Research. 44, 5, p. 2125-35 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Prenatal Choline Supplementation Diminishes Early-Life Iron Deficiency-Induced Reprogramming of Molecular Networks Associated with Behavioral Abnormalities in the Adult Rat Hippocampus

    Tran, P. V., Kennedy, B. C., Pisansky, M. T., Won, Kyoung Jae, Gewirtz, J. C., Simmons, R. A. & Georgieff, M. K., Mar 2016, In : The Journal of Nutrition. 146, 3, p. 484-93 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Histone H4 acetylation and the epigenetic reader Brd4 are critical regulators of pluripotency in embryonic stem cells

    Gonzales-Cope, M., Sidoli, S., Bhanu, N. V., Won, Kyoung Jae & Garcia, B. A., 4 Feb 2016, In : BMC Genomics. 17, p. 95

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. EBF2 promotes the recruitment of beige adipocytes in white adipose tissue

    Stine, R. R., Shapira, S. N., Lim, H., Ishibashi, J., Harms, M., Won, Kyoung Jae & Seale, P., Jan 2016, In : Molecular Metabolism. 5, 1, p. 57-65 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. EBNA2 Drives Formation of New Chromosome Binding Sites and Target Genes for B-Cell Master Regulatory Transcription Factors RBP-jκ and EBF1

    Lu, F., Chen, H., Kossenkov, A. V., DeWispeleare, K., Won, Kyoung Jae & Lieberman, P. M., Jan 2016, In : PLOS Pathogens. 12, 1, p. e1005339

    Research output: Contribution to journalJournal articleResearchpeer-review

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