Cord Herbert Brakebusch

Cord Herbert Brakebusch

ORCID: 0000-0002-9342-1634

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  1. Published

    90K (MAC-2 BP) gene expression in breast cancer and evidence for the production of 90K by peripheral-blood mononuclear cells.

    Fusco, O., Querzoli, P., Nenci, I., Natoli, C., Brakebusch, Cord Herbert, Ullrich, A. & Iacobelli, S., 1998, In: International Journal of Cancer. 79, 1, p. 23-6 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Adgrf5 contributes to patterning of the endothelial deep layer in retina

    Niaudet, C., Petkova, M., Jung, B., Lu, S., Laviña, B., Offermanns, S., Brakebusch, Cord Herbert & Betsholtz, C., 2019, In: Angiogenesis. 22, 4, p. 491-505 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    A Cdc42/RhoA regulatory circuit downstream of glycoprotein Ib guides transendothelial platelet biogenesis

    Dütting, S., Gaits-Iacovoni, F., Stegner, D., Popp, M., Antkowiak, A., Van Eeuwijk, J. M. M., Nurden, P., Stritt, S., Heib, T., Aurbach, K., Angay, O., Cherpokova, D., Heinz, N., Baig, A. A., Gorelashvili, M. G., Gerner, F., Heinze, K. G., Ware, J., Krohne, G., Ruggeri, Z. M. & 6 others, Nurden, A. T., Schulze, H., Modlich, U., Pleines, I., Brakebusch, Cord Herbert & Nieswandt, B., 15 Jun 2017, In: Nature Communications. 8, 13 p., 15838.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    A RhoA-mediated biomechanical response in Schwann cells modulates peripheral nerve myelination

    Seixas, A. I., Morais, M. R. G., Brakebusch, Cord Herbert & Relvas, J. B., 2023, In: Progress in Neurobiology. 227, 13 p., 102481.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    A central role for the small GTPase Rac1 in hippocampal plasticity and spatial learning and memory

    Haditsch, U., Leone, D. P., Farinelli, M., Chrostek-Grashoff, A., Brakebusch, Cord Herbert, Mansuy, I. M., McConnell, S. K. & Palmer, T. D., 2009, In: Molecular and Cellular Neuroscience. 41, 4, p. 409-19 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    A crucial role of beta 1 integrins for keratinocyte migration in vitro and during cutaneous wound repair.

    Grose, R., Hutter, C., Bloch, W., Thorey, I., Watt, F. M., Fässler, R., Brakebusch, Cord Herbert & Werner, S., 2002, In: Development. 129, 9, p. 2303-15 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    A function for Rac1 in the terminal differentiation and pigmentation of hair

    Behrendt, K., Klatte, J., Pofahl, R., Bloch, W., Smyth, N., Tscharntke, M., Krieg, T., Paus, R., Niessen, C., Niemann, C., Brakebusch, Cord Herbert & Haase, I., 24 Jan 2012, In: Journal of Cell Science. 125, Pt 4, p. 896-905 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    A human antithrombin isoform dampens inflammatory responses and protects from organ damage during bacterial infection

    Papareddy, P., Rossnagel, M., Doreen Hollwedel, F., Kilic, G., Veerla, S., Naudin, C., Smeds, E., Westman, J., Martinez-Martinez, I., Egesten, A., de la Morena-Barrio, M. E., Corral, J., Linder, A., Artoni, A., Abbattista, M., Novembrino, C., Brakebusch, Cord Herbert, Martinelli, I., Kasetty, G. & Herwald, H., 2019, In: Nature Microbiology. 4, 12, p. 2442-2455 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    A new genetic tool to improve immune-compromised mouse models: Derivation and CRISPR/Cas9-mediated targeting of NRG embryonic stem cell lines

    Martin Gonzalez, Javier, Baudet, A., Abelechian, Sahar, Bonderup, K., d'Altri, T., Porse, Bo Torben, Brakebusch, Cord Herbert, Juliusson, G. & Cammenga, J., 2018, In: Genesis: The Journal of Genetics and Development (Print). 56, 9, p. 1-7 7 p., e23238.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    A radial glia-specific role of RhoA in double cortex formation

    Cappello, S., Böhringer, C. R. J., Bergami, M., Conzelmann, K., Ghanem, A., Tomassy, G. S., Arlotta, P., Mainardi, M., Allegra, M., Caleo, M., van Hengel, J., Brakebusch, Cord Herbert & Götz, M., 8 Mar 2012, In: Neuron. 73, 5, p. 911-24 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    ACK1 is dispensable for development, skin tumor formation, and breast cancer cell proliferation

    Brandao, R., Kwa, M. Q., Yarden, Y. & Brakebusch, Cord Herbert, 2021, In: FEBS Open Bio. 11, 6, p. 1579-1592 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    ATF3 downmodulates its new targets IFI6 and IFI27 to suppress the growth and migration of tongue squamous cell carcinoma cells

    Xu, L., Zu, T., Li, T., Li, M., Mi, J., Bai, F., Liu, G., Wen, J., Li, H., Brakebusch, Cord Herbert, Wang, X. & Wu, X., 2021, In: PLOS Genetics. 17, 2, p. 1-25 e1009283.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Adult murine hematopoiesis can proceed without beta1 and beta7 integrins.

    Bungartz, G., Stiller, S., Bauer, M., Müller, W., Schippers, A., Wagner, N., Fässler, R. & Brakebusch, Cord Herbert, 2006, In: Blood. 108, 6, p. 1857-64 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Analyzing skin tumor development in mice by the DMBA/TPA model

    Li, H. & Brakebusch, Cord Herbert, 2021, Carcinogen-driven mouse models of oncogenesis. Galluzzi, L. & Buqué, A. (eds.). Elsevier, Vol. 163. p. 113-121 9 p. (Methods in Cell Biology).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  15. Published

    Antibodies to a soluble form of a tumor necrosis factor (TNF) receptor have TNF-like activity.

    Engelmann, H., Holtmann, H., Brakebusch, Cord Herbert, Avni, Y. S., Sarov, I., Nophar, Y., Hadas, E., Leitner, O. & Wallach, D., 1990, In: Journal of Biological Chemistry. 265, 24, p. 14497-504 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Author Correction: FMNL2 and -3 regulate Golgi architecture and anterograde transport downstream of Cdc42

    Kage, F., Steffen, A., Ellinger, A., Ranftler, C., Gehre, C., Brakebusch, Cord Herbert, Pavelka, M., Stradal, T. & Rottner, K., 26 Nov 2019, In: Scientific Reports. 9, 1, p. 18008 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  17. Published

    Beta 1 integrin is essential for teratoma growth and angiogenesis.

    Bloch, W., Forsberg, E., Lentini, S., Brakebusch, Cord Herbert, Martin, K., Krell, H. W., Weidle, U. H., Addicks, K. & Fässler, R., 1997, In: Journal of Cell Biology. 139, 1, p. 265-78 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Beta1 integrin is not essential for hematopoiesis but is necessary for the T cell-dependent IgM antibody response.

    Brakebusch, Cord Herbert, Fillatreau, S., Potocnik, A. J., Bungartz, G., Wilhelm, P., Svensson, M., Kearney, P., Körner, H., Gray, D. & Fässler, R., 2002, In: Immunity. 16, 3, p. 465-77 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Beta1 integrin promotes but is not essential for metastasis of ras-myc transformed fibroblasts.

    Brakebusch, Cord Herbert, Wennerberg, K., Krell, H. W., Weidle, U. H., Sallmyr, A., Johansson, S. & Fässler, R., 1999, In: Oncogene. 18, 26, p. 3852-61 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Beta1 integrin-mediated adhesion signalling is essential for epidermal progenitor cell expansion

    Piwko-Czuchra, A., Koegel, H., Meyer, H., Bauer, M., Werner, S., Brakebusch, Cord Herbert & Fässler, R., 2009, In: PLoS ONE. 4, 5, p. e5488

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Beta1 integrins activate a MAPK signalling pathway in neural stem cells that contributes to their maintenance.

    Campos, L. S., Leone, D. P., Relvas, J. B., Brakebusch, Cord Herbert, Fässler, R., Suter, U. & ffrench-Constant, C., 2004, In: Development. 131, 14, p. 3433-44 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Beta1 integrins differentially control extravasation of inflammatory cell subsets into the CNS during autoimmunity

    Bauer, M., Brakebusch, Cord Herbert, Coisne, C., Sixt, M., Wekerle, H., Engelhardt, B. & Fässler, R., 2009, In: Proceedings of the National Academy of Science of the United States of America. 106, 6, p. 1920-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Beta1 integrins regulate chondrocyte rotation, G1 progression, and cytokinesis.

    Aszodi, A., Hunziker, E. B., Brakebusch, Cord Herbert & Fässler, R., 2003, In: Genes & Development. 17, 19, p. 2465-79 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Brevican-deficient mice display impaired hippocampal CA1 long-term potentiation but show no obvious deficits in learning and memory.

    Brakebusch, Cord Herbert, Seidenbecher, C. I., Asztely, F., Rauch, U., Matthies, H., Meyer, H., Krug, M., Böckers, T. M., Zhou, X., Kreutz, M. R., Montag, D., Gundelfinger, E. D. & Fässler, R., 2002, In: Molecular and Cellular Biology. 22, 21, p. 7417-27 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    CDC42 Deletion Elicits Cerebral Vascular Malformations via Increased MEKK3-Dependent KLF4 Expression

    Castro, M., Laviña, B., Ando, K., Álvarez-Aznar, A., Abu Taha, A., Brakebusch, Cord Herbert, Dejana, E., Betsholtz, C. & Gaengel, K. B., 2019, In: Circulation Research. 124, 8, p. 1240-1252 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    CRISPR Genome Editing: How to Make a Fantastic Method Even Better

    Brakebusch, Cord Herbert, 2021, In: Cells. 10, 2, p. 1-2 408.

    Research output: Contribution to journal › Editorial › Research › peer-review

  27. Published

    Cancer-associated fibroblasts: how do they contribute to metastasis?

    Kwa, M. Q., Herum, K. M. & Brakebusch, Cord Herbert, 2019, In: Clinical and Experimental Metastasis. 36, 2, p. 71-86

    Research output: Contribution to journal › Review › Research › peer-review

  28. Published

    Cardiac fibroblast sub-types in vitro reflect pathological cardiac remodeling in vivo

    Herum, K. M., Weng, Guangzheng, Kahnert, Konstantin, Waikel, R., Milburn, G., Conger, A., Anaya, P., Campbell, K. S., Lundby, Alicia, Won, K. J. & Brakebusch, Cord Herbert, 2022, In: Matrix Biology Plus. 15, 100113.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Cdc42 Controls Vascular Network Assembly Through Protein Kinase C{iota} During Embryonic Vasculogenesis

    Qi, Y., Liu, J., Wu, X., Brakebusch, Cord Herbert, Leitges, M., Han, Y., Corbett, S. A., Lowry, S. F., Graham, A. M. & Li, S., 1 Aug 2011, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 31, 8, p. 1861-70 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Cdc42 and Rab8a are critical for intestinal stem cell division, survival, and differentiation in mice

    Sakamori, R., Das, S., Yu, S., Feng, S., Stypulkowski, E., Guan, Y., Douard, V., Tang, W., Ferraris, R. P., Harada, A., Brakebusch, Cord Herbert, Guo, W. & Gao, N., 1 Mar 2012, In: Journal of Clinical Investigation. 122, 3, p. 1052-65 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Cdc42 and Rac1 signaling are both required for and act synergistically in the correct formation of myelin sheaths in the CNS.

    Thurnherr, T., Benninger, Y., Wu, X., Chrostek, A., Krause, S. M., Nave, K., Franklin, R. J. M., Brakebusch, Cord Herbert, Suter, U. & Relvas, J. B., 2006, In: Journal of Neuroscience. 26, 40, p. 10110-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Cdc42 and phosphoinositide 3-kinase drive Rac-mediated actin polymerization downstream of c-Met in distinct and common pathways.

    Bosse, T., Ehinger, J., Czuchra, A., Benesch, S., Steffen, A., Wu, X., Schloen, K., Niemann, H. H., Scita, G., Stradal, T. E. B., Brakebusch, Cord Herbert & Rottner, K., 2007, In: Molecular and Cellular Biology. 27, 19, p. 6615-28 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin.

    Wu, X., Quondamatteo, F., Lefever, T., Czuchra, A., Meyer, H., Chrostek, A., Paus, R., Langbein, L. & Brakebusch, Cord Herbert, 2006, In: Genes & Development. 20, 5, p. 571-85 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Cdc42 expression in keratinocytes is required for the maintenance of the basement membrane in skin.

    Wu, X., Quondamatteo, F. & Brakebusch, Cord Herbert, 2006, In: Matrix Biology. 25, 8, p. 466-74 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Cdc42 is a key regulator of B cell differentiation and is required for antiviral humoral immunity

    Burbage, M., Keppler, S. J., Gasparrini, F., Martínez-Martín, N., Gaya, M., Feest, C., Domart, M., Brakebusch, Cord Herbert, Collinson, L., Bruckbauer, A. & Batista, F. D., 2015, In: The Journal of Experimental Medicine. 212, 1, p. 53-72

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Cdc42 is crucial for the establishment of epithelial polarity during early mammalian development.

    Wu, X., Li, S., Chrostek-Grashoff, A., Czuchra, A., Meyer, H., Yurchenco, P. D. & Brakebusch, Cord Herbert, 2007, In: Developmental Dynamics. 236, 10, p. 2767-78 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Cdc42 is crucial for the maturation of primordial cell junctions in keratinocytes independent of Rac1

    Du, D., Pedersen, E., Wang, Z., Karlsson, R., Chen, Z., Wu, X. & Brakebusch, Cord Herbert, 2008, In: Experimental Cell Research.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells.

    Czuchra, A., Wu, X., Meyer, H., van Hengel, J., Schroeder, T., Geffers, R., Rottner, K. & Brakebusch, Cord Herbert, 2005, In: Molecular Biology of the Cell. 16, 10, p. 4473-84 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Cdc42 promotes host defenses against fatal infection

    Lee, K., Boyd, K. L., Parekh, D. V., Kehl-Fie, T. E., Baldwin, H. S., Brakebusch, Cord Herbert, Skaar, E. P., Boothby, M. & Zent, R., 20 May 2013, In: Infection and Immunity. 81, 8, p. 2714-2723 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Cdc42 regulates cofilin during the establishment of neuronal polarity.

    Garvalov, B. K., Flynn, K. C., Neukirchen, D., Meyn, L., Teusch, N., Wu, X., Brakebusch, Cord Herbert, Bamburg, J. R. & Bradke, F., 2007, In: Journal of Neuroscience. 27, 48, p. 13117-29 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Cdc42 regulates epithelial cell polarity and cytoskeletal function during kidney tubule development

    Elias, B. C., Das, A., Parekh, D. V., Mernaugh, G., Adams, R., Yang, Z., Brakebusch, Cord Herbert, Pozzi, A., Marciano, D. K., Carroll, T. J. & Zent, R., 1 Dec 2015, In: Journal of Cell Science. 128, 23, p. 4293-305 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Cdc42-dependent actin dynamics controls maturation and secretory activity of dendritic cells

    Schulz, A. M., Stutte, S., Hogl, S., Luckashenak, N., Dudziak, D., Leroy, C., Forné, I., Imhof, A., Müller, S. A., Brakebusch, Cord Herbert, Lichtenthaler, S. F. & Brocker, T., 9 Nov 2015, In: Journal of Cell Biology. 211, 3, p. 553-67 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Cdc42-dependent leading edge coordination is essential for interstitial dendritic cell migration

    Lammermann, T., Renkawitz, J., Wu, X., Hirsch, K., Brakebusch, Cord Herbert & Sixt, M., 2009, In: Blood.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Cdc42-dependent structural development of auditory supporting cells is required for wound healing at adulthood

    Anttonen, T., Kirjavainen, A., Belevich, I., Laos, M., Richardson, W. D., Jokitalo, E., Brakebusch, Cord Herbert & Pirvola, U., 2012, In: Scientific Reports. 2, p. 978

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Cdc42-mediated tubulogenesis controls cell specification

    Kesavan, G., Sand, F. W., Greiner, T. U., Johansson, J. K., Kobberup, S., Wu, X., Brakebusch, Cord Herbert & Semb, Tor Henrik, 2009, In: Cell. 139, 4, p. 791-801 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Changes in dermal matrix in the absence of Rac1 in keratinocytes

    Stanley, A., Pedersen, E. D. K., Brakebusch, Cord Herbert & Quondamatteo, F., May 2016, In: Journal of Anatomy. 228, 5, p. 826-37 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Characterization of TGF-β signaling in a human organotypic skin model reveals that loss of TGF-βRII induces invasive tissue growth

    Ye, Z., Kilic, G., Dabelsteen, Sally, Marinova, I. N., Thøfner, J. F. B., Song, Ming, Levann, Asha Maria Rudjord, Bagdonaite, Ieva , Vakhrushev, Sergey, Brakebusch, Cord Herbert, Olsen, Jesper Velgaard & Wandall, Hans H., 2022, In: Science Signaling. 15, 761, eabo2206.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Clonal reversal of ageing-associated stem cell lineage bias via a pluripotent intermediate

    Wahlestedt, M., Erlandsson, E., Kristiansen, T., Lu, R., Brakebusch, Cord Herbert, Weissman, I. L., Yuan, J., Martin Gonzalez, Javier & Bryder, D., 22 Feb 2017, In: Nature Communications. 8, 8 p., 14533.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Cofilin phosphorylation is elevated after F-actin disassembly induced by Rac1 depletion

    Liu, L., Li, J., Zhang, L., Zhang, F., Zhang, R., Chen, X., Brakebusch, Cord Herbert, Wang, Z. & Liu, X., 27 Oct 2015, In: BioFactors (Oxford, England). 41, 5, p. 352-9 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Complementary roles of glycoprotein VI and alpha2beta1 integrin in collagen-induced thrombus formation in flowing whole blood ex vivo.

    Kuijpers, M. J. E., Schulte, V., Bergmeier, W., Lindhout, T., Brakebusch, Cord Herbert, Offermanns, S., Fässler, R., Heemskerk, J. W. M. & Nieswandt, B., 2003, In: The FASEB Journal. 17, 6, p. 685-7 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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