Cord Herbert Brakebusch

Cord Herbert Brakebusch

ORCID: 0000-0002-9342-1634

Publication year:
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101 - 150 out of 203Page size: 50
  1. 2011
  2. Published

    Rhoh deficiency reduces peripheral T-cell function and attenuates allogenic transplant rejection

    Porubsky, S., Wang, S., Kiss, E., Dehmel, S., Bonrouhi, M., Dorn, T., Luckow, B., Brakebusch, Cord Herbert & Gröne, H., 1 Jan 2011, In: European Journal of Immunology. 41, 1, p. 76-88 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Generation and analysis of genetically modified mice

    Brakebusch, Cord Herbert, 2011, Handbook of Laboratory Animal Science: Essential Principles and Practices. Hau, J. & Schapiro, SJ. (eds.). 3rd ed. Boca Raton, London, New York: CRC Press, Vol. 1.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  4. Published

    Mouse as a Model Organism: From Animals to Cells

    Brakebusch, Cord Herbert (ed.) & Pihlajaniemi, T. (ed.), 2011, Dordrecht: Springer. 165 p.

    Research output: Book/Report › Anthology › Research › peer-review

  5. Accepted/In press

    Rho GTPase knockout induction in primary keratinocytes from adult mice

    Pedersen, E. D. K., Basse, A. L., Lefever, T., Peyrollier, K. C. & Brakebusch, Cord Herbert, 2011, (Accepted/In press) Methods in Rho GTPases. Rivero, F. (ed.). New York: Humana Press

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  6. 2010
  7. Published

    Multiple alterations of platelet functions dominated by increased secretion in mice lacking Cdc42 in platelets

    Pleines, I., Eckly, A., Elvers, M., Hagedorn, I., Eliautou, S., Bender, M., Wu, X., Lanza, F., Gachet, C., Brakebusch, Cord Herbert & Nieswandt, B., 2010, In: Blood. 115, 16, p. 3364-73 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    N-WASP is a novel regulator of hair-follicle cycling that controls antiproliferative TGF{beta} pathways

    Lefever, T., Pedersen, E., Basse, A., Paus, R., Quondamatteo, F., Stanley, A. C., Langbein, L., Wu, X., Wehland, J., Lommel, S. & Brakebusch, Cord Herbert, 2010, In: Journal of Cell Science. 123, Pt 1, p. 128-40 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Rac1 is crucial for Ras-dependent skin tumor formation by controlling Pak1-Mek-Erk hyperactivation and hyperproliferation in vivo

    Wang, Z., Pedersen, E. D. K., Basse, A., Lefever, T., Peyrollier, K., Kapoor, S., Mei, Q., Karlsson, R., Chrostek-Grashoff, A. & Brakebusch, Cord Herbert, 2010, In: Oncogene. 29, 23, p. 3362-73 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Rac1 is essential for basement membrane-dependent epiblast survival

    He, X., Liu, J., Qi, Y., Brakebusch, Cord Herbert, Chrostek-Grashoff, A., Edgar, D., Yurchenco, P. D., Corbett, S. A., Lowry, S. F., Graham, A. M., Han, Y. & Li, S., 2010, In: Molecular and Cellular Biology. 30, 14, p. 3569-81 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Rac1 regulates neuronal polarization through the WAVE complex

    Tahirovic, S., Hellal, F., Neukirchen, D., Hindges, R., Garvalov, B. K., Flynn, K. C., Stradal, T. E., Chrostek-Grashoff, A., Brakebusch, Cord Herbert & Bradke, F., 2010, In: Journal of Neuroscience. 30, 20, p. 6930-43 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Rho GTPase function in cell morphogenesis

    Pedersen, E. D. K. & Brakebusch, Cord Herbert, 2010, ENCYCLOPEDIA OF LIFE SCIENCES. Wiley

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  13. Published

    The rho GTPase Rac1 is required for proliferation and survival of progenitors in the developing forebrain

    Leone, D. P., Srinivasan, K., Brakebusch, Cord Herbert & McConnell, S. K., 2010, In: Developmental Neurobiology. 70, 9, p. 659-78 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. 2009
  15. Published

    A central role for the small GTPase Rac1 in hippocampal plasticity and spatial learning and memory

    Haditsch, U., Leone, D. P., Farinelli, M., Chrostek-Grashoff, A., Brakebusch, Cord Herbert, Mansuy, I. M., McConnell, S. K. & Palmer, T. D., 2009, In: Molecular and Cellular Neuroscience. 41, 4, p. 409-19 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Beta1 integrin-mediated adhesion signalling is essential for epidermal progenitor cell expansion

    Piwko-Czuchra, A., Koegel, H., Meyer, H., Bauer, M., Werner, S., Brakebusch, Cord Herbert & Fässler, R., 2009, In: PLoS ONE. 4, 5, p. e5488

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Beta1 integrins differentially control extravasation of inflammatory cell subsets into the CNS during autoimmunity

    Bauer, M., Brakebusch, Cord Herbert, Coisne, C., Sixt, M., Wekerle, H., Engelhardt, B. & Fässler, R., 2009, In: Proceedings of the National Academy of Science of the United States of America. 106, 6, p. 1920-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Cdc42-dependent leading edge coordination is essential for interstitial dendritic cell migration

    Lammermann, T., Renkawitz, J., Wu, X., Hirsch, K., Brakebusch, Cord Herbert & Sixt, M., 2009, In: Blood.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Cdc42-mediated tubulogenesis controls cell specification

    Kesavan, G., Sand, F. W., Greiner, T. U., Johansson, J. K., Kobberup, S., Wu, X., Brakebusch, Cord Herbert & Semb, Tor Henrik, 2009, In: Cell. 139, 4, p. 791-801 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Hepatocyte-specific deletion of Cdc42 results in delayed liver regeneration after partial hepatectomy in mice

    Yuan, H., Zhang, H., Wu, X., Zhang, Z., Du, D., Zhou, W., Zhou, S., Brakebusch, Cord Herbert & Chen, Z., 2009, In: Hepatology. 49, 1, p. 240-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Rho GTPase function in tumorigenesis

    Karlsson, R., Pedersen, E. D. K., Wang, Z. & Brakebusch, Cord Herbert, 2009, In: BBA General Subjects.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Stage-specific control of neural crest stem cell proliferation by the small rho GTPases Cdc42 and Rac1

    Fuchs, S., Herzog, D., Sumara, G., Büchmann-Møller, S., Civenni, G., Wu, X., Chrostek-Grashoff, A., Suter, U., Ricci, R., Relvas, J. B., Brakebusch, Cord Herbert & Sommer, L., 2009, In: Cell Stem Cell. 4, 3, p. 236-47 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    The small G-proteins Rac1 and Cdc42 are essential for myoblast fusion in the mouse

    Vasyutina, E., Martarelli, B., Brakebusch, Cord Herbert, Wende, H. & Birchmeier, C., 2009, In: Proceedings of the National Academy of Science of the United States of America. 106, 22, p. 8935-40 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. 2008
  25. Published

    Genetically Modified Mice in Medical and Pharmaceutical Research

    Brakebusch, Cord Herbert, 5 Feb 2008, Modern Biopharmaceuticals: Design, Development and Optimization. Wiley-VCH, Vol. 2. p. 649-660 12 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  26. Published

    Cdc42 is crucial for the maturation of primordial cell junctions in keratinocytes independent of Rac1

    Du, D., Pedersen, E., Wang, Z., Karlsson, R., Chen, Z., Wu, X. & Brakebusch, Cord Herbert, 2008, In: Experimental Cell Research.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Continuous cell injury promotes hepatic tumorigenesis in cdc42-deficient mouse liver.

    van Hengel, J., D'Hooge, P., Hooghe, B., Wu, X., Libbrecht, L., De Vos, R., Quondamatteo, F., Klempt, M., Brakebusch, Cord Herbert & van Roy, F., 2008, In: Gastroenterology. 134, 3, p. 781-92 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Functions of Rac1 in the epidermis

    Haase, I. & Brakebusch, Cord Herbert, 2008, In: Journal of Investigative Dermatology. 128, Suppl. 1

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Hepatocyte dysplasia and tumor nodule formation in CDC42-deficient mouse liver

    Hengel, J. V., D'Hooge, P., Wu, X. W., Libbrecht, L., Vos, R. D., Brakebusch, Cord Herbert & Roy, F. V., 2008, In: Acta Clinica Belgica. 63, 1, p. 56-56

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Pigmentation defect due to the deficiency of Rac1 in differentiated parts of the hair follicle

    Behrundt, K., Brakebusch, Cord Herbert, Pofahl, R., Krieg, T. & Hasse, I., 2008, In: Journal of Investigative Dermatology. 128, Suppl. 1

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Rac1 is essential for phospholipase C-gamma2 activation in platelets.

    Pleines, I., Elvers, M., Strehl, A., Pozgajova, M., Varga-Szabo, D., May, F., Chrostek-Grashoff, A., Brakebusch, Cord Herbert & Nieswandt, B., 2008, In: Pflügers Archiv: European Journal of Physiology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. 2007
  33. Published

    Cdc42 and phosphoinositide 3-kinase drive Rac-mediated actin polymerization downstream of c-Met in distinct and common pathways.

    Bosse, T., Ehinger, J., Czuchra, A., Benesch, S., Steffen, A., Wu, X., Schloen, K., Niemann, H. H., Scita, G., Stradal, T. E. B., Brakebusch, Cord Herbert & Rottner, K., 2007, In: Molecular and Cellular Biology. 27, 19, p. 6615-28 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Cdc42 is crucial for the establishment of epithelial polarity during early mammalian development.

    Wu, X., Li, S., Chrostek-Grashoff, A., Czuchra, A., Meyer, H., Yurchenco, P. D. & Brakebusch, Cord Herbert, 2007, In: Developmental Dynamics. 236, 10, p. 2767-78 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Cdc42 regulates cofilin during the establishment of neuronal polarity.

    Garvalov, B. K., Flynn, K. C., Neukirchen, D., Meyn, L., Teusch, N., Wu, X., Brakebusch, Cord Herbert, Bamburg, J. R. & Bradke, F., 2007, In: Journal of Neuroscience. 27, 48, p. 13117-29 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Essential and distinct roles for cdc42 and rac1 in the regulation of Schwann cell biology during peripheral nervous system development.

    Benninger, Y., Thurnherr, T., Pereira, J. A., Krause, S., Wu, X., Chrostek-Grashoff, A., Herzog, D., Nave, K., Franklin, R. J. M., Meijer, D., Brakebusch, Cord Herbert, Suter, U. & Relvas, J. B., 2007, In: Journal of Cell Biology. 177, 6, p. 1051-61 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Impaired epidermal wound healing in vivo upon inhibition or deletion of Rac1.

    Tscharntke, M., Pofahl, R., Chrostek-Grashoff, A., Smyth, N., Niessen, C., Niemann, C., Hartwig, B., Herzog, V., Klein, H. W., Krieg, T., Brakebusch, Cord Herbert & Haase, I., 2007, In: Journal of Cell Science. 120, Pt 8, p. 1480-90 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Leukocyte extravasation as a target for anti-inflammatory therapy - Which molecule to choose? (vol 14, pg 70, 2005)

    Boehncke, W. H., Schon, M. P., Giromolomi, G., Griffiths, C., Bos, J. D., Thestrup-Pedersen, K., Cavani, A., Nestle, F., Bonish, B. K., Campbell, J. J., Brakebusch, Cord Herbert & Nickoloff, B., 2007, In: Experimental Dermatology. 16, 9, p. 778-778

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. 2006
  40. Published

    Adult murine hematopoiesis can proceed without beta1 and beta7 integrins.

    Bungartz, G., Stiller, S., Bauer, M., Müller, W., Schippers, A., Wagner, N., Fässler, R. & Brakebusch, Cord Herbert, 2006, In: Blood. 108, 6, p. 1857-64 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Cdc42 and Rac1 signaling are both required for and act synergistically in the correct formation of myelin sheaths in the CNS.

    Thurnherr, T., Benninger, Y., Wu, X., Chrostek, A., Krause, S. M., Nave, K., Franklin, R. J. M., Brakebusch, Cord Herbert, Suter, U. & Relvas, J. B., 2006, In: Journal of Neuroscience. 26, 40, p. 10110-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin.

    Wu, X., Quondamatteo, F., Lefever, T., Czuchra, A., Meyer, H., Chrostek, A., Paus, R., Langbein, L. & Brakebusch, Cord Herbert, 2006, In: Genes & Development. 20, 5, p. 571-85 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Cdc42 expression in keratinocytes is required for the maintenance of the basement membrane in skin.

    Wu, X., Quondamatteo, F. & Brakebusch, Cord Herbert, 2006, In: Matrix Biology. 25, 8, p. 466-74 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Genetic analysis of beta1 integrin "activation motifs" in mice.

    Czuchra, A., Meyer, H., Legate, K. R., Brakebusch, Cord Herbert & Fässler, R., 2006, In: Journal of Cell Biology. 174, 6, p. 889-99 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Lack of beta1 integrins in enteric neural crest cells leads to a Hirschsprung-like phenotype.

    Breau, M. A., Pietri, T., Eder, O., Blanche, M., Brakebusch, Cord Herbert, Fässler, R., Thiery, J. P. & Dufour, S., 2006, In: Development. 133, 9, p. 1725-34 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Rac1 is crucial for hair follicle integrity but is not essential for maintenance of the epidermis.

    Chrostek, A., Wu, X., Quondamatteo, F., Hu, R., Sanecka, A., Niemann, C., Langbein, L., Haase, I. & Brakebusch, Cord Herbert, 2006, In: Molecular and Cellular Biology. 26, 18, p. 6957-70 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    RhoH is important for positive thymocyte selection and T-cell receptor signaling.

    Dorn, T., Kuhn, U., Bungartz, G., Stiller, S., Bauer, M., Ellwart, J., Peters, T., Scharffetter-Kochanek, K., Semmrich, M., Laschinger, M., Holzmann, B., Klinkert, W. E. F., Straten, P. T., Køllgaard, T., Sixt, M. & Brakebusch, Cord Herbert, 2006, In: Blood. 109, 6, p. 2346-55 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface.

    Cappello, S., Attardo, A., Wu, X., Iwasato, T., Itohara, S., Wilsch-Bräuninger, M., Eilken, H. M., Rieger, M. A., Schroeder, T. T., Huttner, W. B., Brakebusch, Cord Herbert & Götz, M., 2006, In: Nature Neuroscience. 9, 9, p. 1099-107 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Threonine 788 in integrin subunit beta1 regulates integrin activation.

    Nilsson, S., Kaniowska, D., Brakebusch, Cord Herbert, Fässler, R. & Johansson, S., 2006, In: Experimental Cell Research. 312, 6, p. 844-53 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    beta1-integrin-mediated signaling essentially contributes to cell survival after radiation-induced genotoxic injury.

    Cordes, N., Seidler, J., Durzok, R., Geinitz, H. & Brakebusch, Cord Herbert, 2006, In: Oncogene. 25, 9, p. 1378-90 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. 2005

  52. Keratinocyte Migration in Wound Healing

    Brakebusch, Cord Herbert, 9 Aug 2005, Cell Migration in Development and Disease. Wiley-VCH Verlag GmbH & Co. KGaA, p. 275-298 24 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  53. Integrin blockade as therapy in chronic inflammation

    Brakebusch, Cord Herbert, 1 May 2005, In: Experimental Dermatology. 14, 5, 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  54. Published

    Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells.

    Czuchra, A., Wu, X., Meyer, H., van Hengel, J., Schroeder, T., Geffers, R., Rottner, K. & Brakebusch, Cord Herbert, 2005, In: Molecular Biology of the Cell. 16, 10, p. 4473-84 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Interactions of the integrin subunit beta1A with protein kinase B/Akt, p130Cas and paxillin contribute to regulation of radiation survival.

    Seidler, J., Durzok, R., Brakebusch, Cord Herbert & Cordes, N., 2005, In: Radiotherapy & Oncology. 76, 2, p. 129-34 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Leukocyte extravasation as a target for anti-inflammatory therapy - Which molecule to choose?

    Boehncke, W., Schön, M. P., Girolomoni, G., Giromolomi, G., Griffiths, C., Bos, J. D., Thestrup-Pedersen, K., Cavani, A., Nestle, F., Bonish, B. K., Campbell, J. J., Brakebusch, Cord Herbert & Nickoloff, B., 2005, In: Experimental Dermatology. 14, 1, p. 70-80 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Regulation of neural progenitor proliferation and survival by beta1 integrins.

    Leone, D. P., Relvas, J. B., Campos, L. S., Hemmi, S., Brakebusch, Cord Herbert, Fässler, R., Ffrench-Constant, C. & Suter, U., 2005, In: Journal of Cell Science. 118, Pt 12, p. 2589-99 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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