Lars Henning Engelholm

Lars Henning Engelholm

ORCID: 0000-0002-6616-1232

Publication year:
All
1 - 25 out of 67Page size: 25
  1. 2024
  2. Published

    Antibody–Drug Conjugates: The Dynamic Evolution from Conventional to Next-Generation Constructs

    Metrangolo, Virginia & Engelholm, Lars Henning, 2024, In: Cancers. 16, 2, 20 p., 447.

    Research output: Contribution to journal › Review › Research › peer-review

  3. 2023
  4. Published

    A platform for efficient establishment and drug-response profiling of high-grade serous ovarian cancer organoids

    Senkowski, W., Gall-Mas, L., Falco, M. M., Li, Y., Lavikka, K., Kriegbaum, M. C., Oikkonen, J., Bulanova, D., Pietras, E. J., Voßgröne, K., Chen, Y. J., Erkan, E. P., Dai, J., Lundgren, A., Grønning Høg, M. K., Larsen, I. M., Lamminen, T., Kaipio, K., Huvila, J., Virtanen, A. & 9 others, Engelholm, Lars Henning, Christiansen, P., Santoni Rugiu, Eric, Huhtinen, K., Carpén, O., Hynninen, J., Hautaniemi, S., Vähärautio, A. & Wennerberg, Krister, 2023, In: Developmental Cell. 58, 12, p. 1106-1121.e7 24 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Targeted delivery of alcohol-containing payloads with antibody-drug conjugates

    Grier, K. E., Hansen, A. H., Haxvig, C. S., Li, Xin, Krigslund, O., Behrendt, Niels, Engelholm, Lars Henning, Rossi, F., Sousa, B. C., Harradence, G. J., Camper, N. & Qvortrup, K. M., 2023, In: Chemical Communications. 59, 47, p. 7240-7242

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. 2022
  7. Published

    Hypomorphic expression of parathyroid Bmal1 disrupts the internal parathyroid circadian clock and increases parathyroid cell proliferation in response to uremia

    Egstrand, S., Mace, M. L., Morevati, M., Nordholm, A., Engelholm, Lars Henning, Thomsen, J. S., Brüel, A., Naveh-Many, T., Guo, Y., Ølgaard, Klaus & Lewin, E., Jun 2022, In: Kidney International. 101, 6, p. 1232-1250 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Blockade of beta-adrenergic receptors reduces cancer growth and enhances the response to anti-CTLA4 therapy by modulating the tumor microenvironment

    Fjæstad, K. Y., Rømer, A. M. A., Goitea, V., Johansen, A. Z., Thorseth, M. L., Carretta, M., Engelholm, Lars Henning, Grøntved, L., Junker, N. & Madsen, Daniel Hargbøl, 2022, In: Oncogene. 41, p. 1364-1375

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    The endocytic receptor uPARAP is a regulator of extracellular thrombospondin-1

    Nørregaard, Kirstine Sandal, Jürgensen, Henrik Jessen, Ingvarsen, S. Z., Heltberg, S. S., Hagensen, C. E., Gårdsvoll, Henrik, Madsen, D. H., Jensen, O. N., Engelholm, Lars Henning & Behrendt, Niels, 2022, In: Matrix Biology. 111, p. 307-328 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Uncovering mediators of collagen degradation in the tumor microenvironment

    Thorseth, M. L., Carretta, M., Jensen, C., Mølgaard, K., Jürgensen, Henrik Jessen, Engelholm, Lars Henning, Behrendt, Niels, Willumsen, N. & Madsen, Daniel Hargbøl, 2022, In: Matrix Biology Plus. 13, 100101.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. 2021
  12. Published

    Osteosarcoma and metastasis associated bone degradation—a tale of osteoclast and malignant cell cooperativity

    Nørregaard, Kirstine Sandal, Jürgensen, Henrik Jessen, Gårdsvoll, Henrik, Engelholm, Lars Henning, Behrendt, Niels & Søe, K., 2021, In: International Journal of Molecular Sciences. 22, 13, 6865.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    The Collagen Receptor uPARAP in Malignant Mesothelioma: A Potential Diagnostic Marker and Therapeutic Target

    Cakilkaya, Pinar, Sørensen, R. R., Jürgensen, Henrik Jessen, Krigslund, O., Gårdsvoll, Henrik, Nielsen, C. F., Santoni Rugiu, Eric, Behrendt, Niels & Engelholm, Lars Henning, 2021, In: International Journal of Molecular Sciences. 22, 21, 17 p., 11452.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    The Urokinase Receptor (uPAR) as a “Trojan Horse” in Targeted Cancer Therapy: Challenges and Opportunities

    Metrangolo, Virginia, Ploug, Michael & Engelholm, Lars Henning, 2021, In: Cancers. 13, 21, 45 p., 5376.

    Research output: Contribution to journal › Review › Research › peer-review

  15. 2020
  16. Published

    Personalized B cell response to the Lactobacillus rhamnosus GG probiotic in healthy human subjects: a randomized trial

    Lange, Jette Bornholdt, Chen, Y., Rago, Alfredo, Sloth, S., Hendel, J., Melsæther, C., Müller, C. V., Juul Nielsen, M., Strickertsson, J., Engelholm, Lars Henning, Vitting-Seerup, K., Jensen, Kim Bak, Baker, A. & Sandelin, Albin Gustav, 9 Nov 2020, In: Gut Microbes. 12, 1, p. 1-14 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Cellular uptake of collagens and implications for immune cell regulation in disease

    Jürgensen, Henrik Jessen, van Putten, Sander Maarten, Nørregaard, Kirstine Sandal, Bugge, T. H., Engelholm, Lars Henning, Behrendt, Niels & Madsen, D. H., 2020, In: Cellular and Molecular Life Sciences. 77, 16, p. 3161-3176

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    The collagen receptor uPARAP/Endo180 regulates collectins through unique structural elements in its FNII domain

    Nørregaard, Kirstine Sandal, Krigslund, O., Behrendt, Niels, Engelholm, Lars Henning & Jürgensen, Henrik Jessen, 2020, In: Journal of Biological Chemistry. 295, 27, p. 9157-9170 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Tumor cell MT1-MMP is dispensable for osteosarcoma tumor growth, bone degradation and lung metastasis

    Ingvarsen, S. Z., Gårdsvoll, Henrik, van Putten, Sander Maarten, Nørregaard, Kirstine Sandal, Krigslund, O., Meilstrup, Josephine Amalie, Tran, C., Jürgensen, Henrik Jessen, Melander, M. C., Nielsen, Carsten Haagen, Kjær, Andreas, Bugge, T. H., Engelholm, Lars Henning & Behrendt, Niels, 2020, In: Scientific Reports. 10, 1, p. 1-16 19138.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. 2019
  21. Published

    Immune regulation by fibroblasts in tissue injury depends on uPARAP-mediated uptake of collectins

    Jürgensen, Henrik Jessen, Nørregaard, Kirstine Sandal, Sibree, M. M., Santoni Rugiu, Eric, Madsen, Daniel Hargbøl, Wassilew, K., Krustrup, D., Garred, Peter, Bugge, T. H., Engelholm, Lars Henning & Behrendt, Niels, 1 Jan 2019, In: Journal of Cell Biology. 218, 1, p. 333-349 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    CCL2/MCP-1 signaling drives extracellular matrix turnover by diverse macrophage subsets

    Jürgensen, Henrik Jessen, Silva, L. M., Krigslund, O., Van Putten, S., Madsen, D. H., Behrendt, Niels, Engelholm, Lars Henning & Bugge, T. H., 2019, In: Matrix Biology Plus. 1, p. 1-20 100003.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Collagen density regulates the activity of tumor-infiltrating T cells

    Kuczek, D. E., Larsen, A. M. H., Thorseth, M., Carretta, M., Kalvisa, A., Siersbæk, M. S., Simões, A. M. C., Roslind, A., Engelholm, Lars Henning, Noessner, E., dqp123, dqp123, Svane, Inge Marie, Straten, P. T., Grøntved, L. & Madsen, D. H., 2019, In: Journal for ImmunoTherapy of Cancer. 7, 1, 15 p., 68.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. 2018
  25. Published

    uPARAP/Endo180 receptor is a gatekeeper of VEGFR-2/VEGFR-3 heterodimerisation during pathological lymphangiogenesis

    Durré, T., Morfoisse, F., Erpicum, C., Ebroin, M., Blacher, S., García-Caballero, M., Deroanne, C., Louis, T., Balsat, C., Van de Velde, M., Kaijalainen, S., Kridelka, F., Engelholm, Lars Henning, Struman, I., Alitalo, K., Behrendt, Niels, Paupert, J. & Noel, A., 5 Dec 2018, In: Nature Communications. 9, 1, p. 1-16 5178.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Assessment Of The Correlation Between Dynamic Contrast Enhanced Computed Tomography And Histological And Vascular Biomarkers In Patients Resected For Colorectal Liver Metastases

    Lauridsen, C., Axelsen, T., Hansen, M. L., Fallentin, E., Nielsen, Michael Bachmann, Eefsen, R. L., Illemann, M., Engelholm, Lars Henning, Vainer, B., Hoyer-hansen, G., Lund, I. K., Willemoe, G. L., Rolff, H. C., Mogensen, M. B. & Osterlind, K., 2018, In: Imaging in Medicine. 10, 6, p. 147-154

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. 2017
  28. Published

    CRISPR/Cas9 Engineering of Adult Mouse Liver Demonstrates That the Dnajb1–Prkaca Gene Fusion Is Sufficient to Induce Tumors Resembling Fibrolamellar Hepatocellular Carcinoma

    Engelholm, Lars Henning, Riaz, A., Serra, Denise, Dagnæs-Hansen, F., Johansen, Jens Vilstrup, Santoni Rugiu, Eric, Hansen, S. H., Niola, Francesco & Frödin, Morten, 1 Dec 2017, In: Gastroenterology. 153, 6, p. 1662-1673.e10

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Phagocytosis of Collagen Fibrils by Fibroblasts In Vivo is Independent of the uPARAP/Endo180 Receptor

    Sprangers, S., Behrendt, Niels, Engelholm, Lars Henning, Cao, Y. & Everts, V., Jun 2017, In: Journal of Cellular Biochemistry. 118, 6, p. 1590-1595

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    The focal adhesion-associated proteins DOCK5 and GIT2 comprise a rheostat in control of epithelial invasion

    Frank, S. R., Köllmann, C. P., van Lidth de Jeude, J. F., Thiagarajah, J. R., Engelholm, Lars Henning, Frödin, Morten & Hansen, S. H., 30 Mar 2017, In: Oncogene. 36, 13, p. 1816-1828 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    The collagen receptor uPARAP/Endo180 as a novel target for antibody-drug conjugate mediated treatment of mesenchymal and leukemic cancers

    Nielsen, C. F., van Putten, S. M., Lund, I. K., Melander, M. C., Nørregaard, Kirstine Sandal, Jürgensen, Henrik Jessen, Reckzeh, K., Christensen, K. R., Ingvarsen, S. Z., Gårdsvoll, Henrik, Jensen, K. E., Hamerlik, P., Engelholm, Lars Henning & Behrendt, Niels, 2017, In: OncoTarget. 8, 27, p. 44605-44624 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. 2016
  33. Published

    Crystal structures of the ligand-binding region of uPARAP: effect of calcium ion binding

    Yuan, C., Jürgensen, Henrik Jessen, Engelholm, Lars Henning, Li, R., Liu, M., Jiang, L., Luo, Z., Behrendt, Niels & Huang, M., 1 Aug 2016, In: Biochemical Journal. 473, 15, p. 2359-68 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    C4.4A gene ablation is compatible with normal epidermal development and causes modest overt phenotypes

    Kriegbaum, M. C., Jacobsen, B., Fuchtbauer, A., Hansen, Gert Helge, Christensen, I. J., Friis, Carsten, Persson, M., Engelholm, Lars Henning, Madsen, A. N., Di Meo, I., Lund, I. K., Holst, Birgitte, Kjær, Andreas, Laerum, O. D., Fuchtbauer, E. & Ploug, Michael, 12 May 2016, In: Scientific Reports. 6, 25833.

    Research output: Contribution to journal › Journal article › Research › peer-review

Previous 1 2 3 Next

ID: 9647887