Lars Henning Engelholm

Lars Henning Engelholm


  1. 2016
  2. Published

    Targeting a novel bone degradation pathway in primary bone cancer by inactivation of the collagen receptor uPARAP/Endo180

    Engelholm, Lars Henning, Carlsen Melander, E. M., Hald, A., Persson, M., Madsen, D. H., Jürgensen, Henrik Jessen, Johansson, K., Nielsen, C., Nørregaard, Kirstine Sandal, Ingvarsen, S. Z., Kjær, Andreas, Trovik, C. S., Lærum, O. D., Bugge, T. H., Eide, J. & Behrendt, Niels, Jan 2016, In: Journal of Pathology. 238, 1, p. 120-33 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Microvessel density and endothelial cell proliferation levels in colorectal liver metastases from patients given neo-adjuvant cytotoxic chemotherapy and bevacizumab

    Eefsen, R. L., Engelholm, Lars Henning, Willemoe, G. L., Van den Eynden, G. G., Laerum, O. D., Christensen, I. J., Rolff, H. C., Høyer-Hansen, G., Osterlind, K., Vainer, B. & Illemann, M., 1 Apr 2016, In: International Journal of Cancer. 138, 7, p. 1777-84 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    C4.4A gene ablation is compatible with normal epidermal development and causes modest overt phenotypes

    Kriegbaum, M. C., Jacobsen, B., Fuchtbauer, A., Hansen, Gert Helge, Christensen, I. J., Friis, Carsten, Persson, M., Engelholm, Lars Henning, Madsen, A. N., Di Meo, I., Lund, I. K., Holst, Birgitte, Kjær, Andreas, Laerum, O. D., Fuchtbauer, E. & Ploug, Michael, 12 May 2016, In: Scientific Reports. 6, 25833.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Crystal structures of the ligand-binding region of uPARAP: effect of calcium ion binding

    Yuan, C., Jürgensen, Henrik Jessen, Engelholm, Lars Henning, Li, R., Liu, M., Jiang, L., Luo, Z., Behrendt, Niels & Huang, M., 1 Aug 2016, In: Biochemical Journal. 473, 15, p. 2359-68 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2017
  7. Published

    The collagen receptor uPARAP/Endo180 as a novel target for antibody-drug conjugate mediated treatment of mesenchymal and leukemic cancers

    Nielsen, C. F., van Putten, S. M., Lund, I. K., Melander, M. C., Nørregaard, Kirstine Sandal, Jürgensen, Henrik Jessen, Reckzeh, K., Christensen, K. R., Ingvarsen, S. Z., Gårdsvoll, Henrik, Jensen, K. E., Hamerlik, P., Engelholm, Lars Henning & Behrendt, Niels, 2017, In: OncoTarget. 8, 27, p. 44605-44624 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The focal adhesion-associated proteins DOCK5 and GIT2 comprise a rheostat in control of epithelial invasion

    Frank, S. R., Köllmann, C. P., van Lidth de Jeude, J. F., Thiagarajah, J. R., Engelholm, Lars Henning, Frödin, Morten & Hansen, S. H., 30 Mar 2017, In: Oncogene. 36, 13, p. 1816-1828 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Phagocytosis of Collagen Fibrils by Fibroblasts In Vivo is Independent of the uPARAP/Endo180 Receptor

    Sprangers, S., Behrendt, Niels, Engelholm, Lars Henning, Cao, Y. & Everts, V., Jun 2017, In: Journal of Cellular Biochemistry. 118, 6, p. 1590-1595

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    CRISPR/Cas9 Engineering of Adult Mouse Liver Demonstrates That the Dnajb1–Prkaca Gene Fusion Is Sufficient to Induce Tumors Resembling Fibrolamellar Hepatocellular Carcinoma

    Engelholm, Lars Henning, Riaz, A., Serra, Denise, Dagnæs-Hansen, F., Johansen, Jens Vilstrup, Santoni Rugiu, Eric, Hansen, S. H., Niola, Francesco & Frödin, Morten, 1 Dec 2017, In: Gastroenterology. 153, 6, p. 1662-1673.e10

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2018
  12. Published

    Assessment Of The Correlation Between Dynamic Contrast Enhanced Computed Tomography And Histological And Vascular Biomarkers In Patients Resected For Colorectal Liver Metastases

    Lauridsen, C., Axelsen, T., Hansen, M. L., Fallentin, E., Nielsen, Michael Bachmann, Eefsen, R. L., Illemann, M., Engelholm, Lars Henning, Vainer, B., Hoyer-hansen, G., Lund, I. K., Willemoe, G. L., Rolff, H. C., Mogensen, M. B. & Osterlind, K., 2018, In: Imaging in Medicine. 10, 6, p. 147-154

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    uPARAP/Endo180 receptor is a gatekeeper of VEGFR-2/VEGFR-3 heterodimerisation during pathological lymphangiogenesis

    Durré, T., Morfoisse, F., Erpicum, C., Ebroin, M., Blacher, S., García-Caballero, M., Deroanne, C., Louis, T., Balsat, C., Van de Velde, M., Kaijalainen, S., Kridelka, F., Engelholm, Lars Henning, Struman, I., Alitalo, K., Behrendt, Niels, Paupert, J. & Noel, A., 5 Dec 2018, In: Nature Communications. 9, 1, p. 1-16 5178.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 9647887