Lars Henning Engelholm

Lars Henning Engelholm


  1. 1997
  2. Published

    Differential gene expression in human mammary carcinoma cells: Identification of a new member of a receptor family

    Schiemann, S., Rückels, M., Engelholm, Lars Henning, Schwirzke, M., Brünner, N. & Weidle, U. H., 1997, In: Anticancer Research. 17, 1 A, p. 13-20 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Identification of a novel membrane protein that interacts specifically with the upar-prourokinase complex

    Behrendt, Niels, Engelholm, Lars Henning, Jensen, O. N., Mörtz, E., Ranne, E., Mann, Matthias & Dan, K., 1997, In: Fibrinolysis and Proteolysis. 11, Supl. 3, p. 10 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  4. Published

    Isolation and characterization of gene expression in non-metastasizing versus metastasizing human breast cancer cells

    Engelholm, Lars Henning, Kiilgaard, Jens Folke, Frandsen, T. L. & Fuqua, S., 1 Dec 1997, In: Fibrinolysis and Proteolysis. 11, SUPPL. 3, 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 1998
  6. Published

    Plasminogen activator inhibitor type 1 (PAI-1) in cancer: A potential new target for antiinvasive and antimetastatic therapy

    Frandsen, T. L., Stephens, R. W., Pedersen, A. N., Engelholm, Lars Henning, Holst-Hansen, C. & Brünner, N., Aug 1998, In: Drugs of the Future. 23, 8, p. 873-883 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  7. 2000
  8. A urokinase receptor-associated protein with specific collagen binding properties

    Behrendt, Niels, Jensen, O. N., Engelholm, Lars Henning, Mørtz, E., Mann, Matthias & Danø, K., 2000, In: The Journal of Biological Chemistry. 275, 3, p. 1993-2002 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2001
  10. Published

    The urokinase receptor associated protein (uPARAP/endo180): a novel internalization receptor connected to the plasminogen activation system

    Engelholm, Lars Henning, Nielsen, B. S., Danø, K. & Behrendt, Niels, Jan 2001, In: Trends in Cardiovascular Medicine. 11, 1, p. 7-13 7 p.

    Research output: Contribution to journalReviewResearchpeer-review

  11. Published

    Differential binding of urokinase and peptide antagonists to the urokinase receptor: evidence from characterization of the receptor in four primate species

    Engelholm, Lars Henning & Behrendt, Niels, Mar 2001, In: Biological Chemistry. 382, 3, p. 435-42 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Identification of two estrogen regulated genes associated with growth regulation of human breast cancer

    Ohlsson, H., Brünner, N., Engelholm, Lars Henning, Lundholt, B. K., Weidle, U., Briand, P. & Lykkesfeldt, A. E., 20 Aug 2001, In: Molecular and Cellular Endocrinology. 182, 1, p. 1-11 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    The urokinase plasminogen activator receptor-associated protein/endo180 is coexpressed with its interaction partners urokinase plasminogen activator receptor and matrix metalloprotease-13 during osteogenesis

    Engelholm, Lars Henning, Nielsen, B. S., Netzel-Arnett, S., Solberg, H., Chen, X. D., Lopez Garcia, J. M., López-Otín, C., Young, M. F., Birkedal-Hansen, H., Danø, K., Lund, L. R., Behrendt, Niels & Bugge, T. H., Oct 2001, In: Laboratory Investigation. 81, 10, p. 1403-14 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2002
  15. Published

    Urokinase receptor-associated protein (uPARAP) is expressed in connection with malignant as well as benign lesions of the human breast and occurs in specific populations of stromal cells

    Schnack Nielsen, B., Rank, F., Engelholm, Lars Henning, Holm, A., Danø, K. & Behrendt, Niels, 10 Apr 2002, In: International Journal of Cancer. Supplement. 98, 5, p. 656-64 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Matriptase/MT-SP1 is required for postnatal survival, epidermal barrier function, hair follicle development, and thymic homeostasis

    List, K., Haudenschild, C. C., Szabo, R., Chen, W., Wahl, S. M., Swaim, W., Engelholm, Lars Henning, Behrendt, Niels & Bugge, T. H., 23 May 2002, In: Oncogene. 21, 23, p. 3765-79 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2003
  18. Published

    uPARAP/Endo180 is essential for cellular uptake of collagen and promotes fibroblast collagen adhesion

    Engelholm, Lars Henning, List, K., Netzel-Arnett, S., Cukierman, E., Mitola, D. J., Aaronson, H., Kjøller, L., Larsen, J. K., Yamada, K. M., Strickland, D. K., Holmbeck, Kenn, Danø, K., Birkedal-Hansen, H., Behrendt, Niels & Bugge, T. H., 31 Mar 2003, In: Journal of Cell Biology. 160, 7, p. 1009-15 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2004
  20. Published

    uPARAP/endo180 directs lysosomal delivery and degradation of collagen IV

    Kjøller, L., Engelholm, Lars Henning, Høyer-Hansen, M., Danø, K., Bugge, T. H. & Behrendt, Niels, 1 Feb 2004, In: Experimental Cell Research. 293, 1, p. 106-16 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2005
  22. Intracellular collagen degradation mediated by uPARAP/Endo180 is a major pathway of extracellular matrix turnover during malignancy

    Curino, A. C., Engelholm, Lars Henning, Yamada, S. S., Holmbeck, K., Lund, L. R., Molinolo, A. A., Behrendt, Niels, Nielsen, B. S. & Bugge, T. H., 2005, In: Journal of Cell Biology. 169, 6, p. 977-985 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. 2007
  24. Published

    Increased expression of the collagen internalization receptor uPARAP/Endo180 in the stroma of head and neck cancer

    Sulek, J., Wagenaar-Miller, R. A., Shireman, J., Molinolo, A., Madsen, Daniel Hargbøl, Engelholm, Lars Henning, Behrendt, Niels & Bugge, T. H., Apr 2007, In: Journal of Histochemistry and Cytochemistry. 55, 4, p. 347-53 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Complementary roles of intracellular and pericellular collagen degradation pathways in vivo

    Wagenaar-Miller, R. A., Engelholm, Lars Henning, Gavard, J., Yamada, S. S., Gutkind, J. S., Behrendt, Niels, Bugge, T. H. & Holmbeck, Kenn, Sep 2007, In: Molecular and Cellular Biology. 27, 18, p. 6309-22 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation

    Madsen, Daniel Hargbøl, Engelholm, Lars Henning, Ingvarsen, S., Hillig, T., Wagenaar-Miller, R. A., Kjøller, L., Gårdsvoll, Henrik, Høyer-Hansen, G., Holmbeck, Kenn, Bugge, T. H. & Behrendt, Niels, 14 Sep 2007, In: The Journal of Biological Chemistry. 282, 37, p. 27037-45 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2008
  28. Published

    A composite role of vitronectin and urokinase in the modulation of cell morphology upon expression of the urokinase receptor

    Hillig, T., Engelholm, Lars Henning, Ingvarsen, S., Madsen, Daniel Hargbøl, Gårdsvoll, Henrik, Larsen, J. K., Ploug, Michael, Danø, K., Kjøller, L. & Behrendt, Niels, 30 May 2008, In: Journal of Biological Chemistry. 283, 22, p. 15217-15223 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. 2009
  30. Published

    The collagen receptor uPARAP/Endo180

    Engelholm, Lars Henning, Ingvarsen, S., Jürgensen, H. J., Hillig, T., Madsen, D. H., Nielsen, B. S. & Behrendt, N., 2009, In: Frontiers in Bioscience. 14, p. 2103-2114 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    The collagen receptor uPARAP/Endo180

    Engelholm, Lars Henning, Ingvarsen, S., Jürgensen, Henrik Jessen, Hillig, T., Madsen, Daniel Hargbøl, Nielsen, B. S. & Behrendt, Niels, 1 Jan 2009, In: Frontiers in Bioscience. 14, p. 2103-14 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  32. 2010
  33. Fibroblast growth factor receptor 4 regulates tumor invasion by coupling fibroblast growth factor signaling to extracellular matrix degradation

    Sugiyama, N., Varjosalo, M., Meller, P., Lohi, J., Hyytiäinen, M., Kilpinen, S., Kallioniemi, O., Ingvarsen, S., Engelholm, Lars Henning, Taipale, J., Alitalo, K., Keski-Oja, J. & Lehti, K., 15 Oct 2010, In: Accomplishments in Cancer Research. 70, 20, p. 7851-61 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. 2011
  35. Published

    A novel functional role of collagen glycosylation: interaction with the endocytic collagen receptor uPARAP/ENDO 180

    Jürgensen, Henrik Jessen, Madsen, Daniel Hargbøl, Ingvarsen, S., Melander, M. C., Gårdsvoll, Henrik, Patthy, L., Engelholm, Lars Henning & Behrendt, Niels, 2011, In: Journal of Biological Chemistry. 286, 37, p. 32736-48 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    The non-phagocytic route of collagen uptake: a distinct degradation pathway

    Madsen, Daniel Hargbøl, Ingvarsen, S., Jürgensen, Henrik Jessen, Melander, M. C., Kjøller, L., Moyer, A., Honoré, C., Madsen, M. C., Garred, Peter, Burgdorf, S., Bugge, T. H., Behrendt, Niels & Engelholm, Lars Henning, 29 Jul 2011, In: The Journal of Biological Chemistry. 286, 30, p. 26996-7010 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Conformational regulation of urokinase receptor function: impact of receptor occupancy and epitope-mapped monoclonal antibodies on lamellipodia induction

    Gårdsvoll, Henrik, Jacobsen, B., Kriegbaum, M. C., Behrendt, Niels, Engelholm, Lars Henning, Østergaard, S. & Ploug, Michael, 23 Sep 2011, In: The Journal of Biological Chemistry. 286, 38, p. 33544-56 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. 2012
  39. Published

    Inhibitory Monoclonal Antibodies against Mouse Proteases Raised in Gene-Deficient Mice Block Proteolytic Functions in vivo

    Lund, I. K., Rasch, M. G., Ingvarsen, S., Pass, J., Madsen, Daniel Hargbøl, Engelholm, Lars Henning, Behrendt, Niels & Høyer-Hansen, G., 2012, In: Frontiers in Pharmacology. 3, p. 122

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 9647887