Lars Henning Engelholm

Lars Henning Engelholm

ORCID: 0000-0002-6616-1232

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  1. Published

    A composite role of vitronectin and urokinase in the modulation of cell morphology upon expression of the urokinase receptor

    Hillig, T., Engelholm, Lars Henning, Ingvarsen, S., Madsen, Daniel Hargbøl, Gårdsvoll, Henrik, Larsen, J. K., Ploug, Michael, Danø, K., Kjøller, L. & Behrendt, Niels, 30 May 2008, In: Journal of Biological Chemistry. 283, 22, p. 15217-15223 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    A novel functional role of collagen glycosylation: interaction with the endocytic collagen receptor uPARAP/ENDO 180

    Jürgensen, Henrik Jessen, Madsen, Daniel Hargbøl, Ingvarsen, S., Melander, M. C., Gårdsvoll, Henrik, Patthy, L., Engelholm, Lars Henning & Behrendt, Niels, 2011, In: Journal of Biological Chemistry. 286, 37, p. 32736-48 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    A platform for efficient establishment and drug-response profiling of high-grade serous ovarian cancer organoids

    Senkowski, W., Gall-Mas, L., Falco, M. M., Li, Y., Lavikka, K., Kriegbaum, M. C., Oikkonen, J., Bulanova, D., Pietras, E. J., Voßgröne, K., Chen, Y. J., Erkan, E. P., Dai, J., Lundgren, A., Grønning Høg, M. K., Larsen, I. M., Lamminen, T., Kaipio, K., Huvila, J., Virtanen, A. & 9 others, Engelholm, Lars Henning, Christiansen, P., Santoni Rugiu, Eric, Huhtinen, K., Carpén, O., Hynninen, J., Hautaniemi, S., Vähärautio, A. & Wennerberg, Krister, 2023, In: Developmental Cell. 58, 12, p. 1106-1121.e7 24 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    A supra-cellular model for coupling of bone resorption to formation during remodeling: lessons from two bone resorption inhibitors affecting bone formation differently

    Jensen, P. R., Andersen, T. L., Pennypacker, B. L., Duong, L. T., Engelholm, Lars Henning & Delaissé, J., 10 Jan 2014, In: Biochemical and Biophysical Research Communications. 443, 2, p. 694-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. A urokinase receptor-associated protein with specific collagen binding properties

    Behrendt, Niels, Jensen, O. N., Engelholm, Lars Henning, Mørtz, E., Mann, Matthias & Danø, K., 2000, In: The Journal of Biological Chemistry. 275, 3, p. 1993-2002 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Advances in targeted delivery of small interfering RNA using simple bioconjugates

    Nielsen, C., Kjems, J., Sørensen, K. R., Engelholm, Lars Henning & Behrendt, Niels, 2014, In: Expert Opinion on Drug Delivery. 11, 5, p. 791-822 32 p.

    Research output: Contribution to journal › Review › Research › peer-review

  7. Published

    Antibody–Drug Conjugates: The Dynamic Evolution from Conventional to Next-Generation Constructs

    Metrangolo, Virginia & Engelholm, Lars Henning, 2024, In: Cancers. 16, 2, 20 p., 447.

    Research output: Contribution to journal › Review › Research › peer-review

  8. Published

    Assessment Of The Correlation Between Dynamic Contrast Enhanced Computed Tomography And Histological And Vascular Biomarkers In Patients Resected For Colorectal Liver Metastases

    Lauridsen, C., Axelsen, T., Hansen, M. L., Fallentin, E., Nielsen, Michael Bachmann, Eefsen, R. L., Illemann, M., Engelholm, Lars Henning, Vainer, B., Hoyer-hansen, G., Lund, I. K., Willemoe, G. L., Rolff, H. C., Mogensen, M. B. & Osterlind, K., 2018, In: Imaging in Medicine. 10, 6, p. 147-154

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Blockade of beta-adrenergic receptors reduces cancer growth and enhances the response to anti-CTLA4 therapy by modulating the tumor microenvironment

    Fjæstad, K. Y., Rømer, A. M. A., Goitea, V., Johansen, A. Z., Thorseth, M. L., Carretta, M., Engelholm, Lars Henning, Grøntved, L., Junker, N. & Madsen, Daniel Hargbøl, 2022, In: Oncogene. 41, p. 1364-1375

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    C4.4A gene ablation is compatible with normal epidermal development and causes modest overt phenotypes

    Kriegbaum, M. C., Jacobsen, B., Fuchtbauer, A., Hansen, Gert Helge, Christensen, I. J., Friis, Carsten, Persson, M., Engelholm, Lars Henning, Madsen, A. N., Di Meo, I., Lund, I. K., Holst, Birgitte, Kjær, Andreas, Laerum, O. D., Fuchtbauer, E. & Ploug, Michael, 12 May 2016, In: Scientific Reports. 6, 25833.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    CCL2/MCP-1 signaling drives extracellular matrix turnover by diverse macrophage subsets

    Jürgensen, Henrik Jessen, Silva, L. M., Krigslund, O., Van Putten, S., Madsen, D. H., Behrendt, Niels, Engelholm, Lars Henning & Bugge, T. H., 2019, In: Matrix Biology Plus. 1, p. 1-20 100003.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    CRISPR/Cas9 Engineering of Adult Mouse Liver Demonstrates That the Dnajb1–Prkaca Gene Fusion Is Sufficient to Induce Tumors Resembling Fibrolamellar Hepatocellular Carcinoma

    Engelholm, Lars Henning, Riaz, A., Serra, Denise, Dagnæs-Hansen, F., Johansen, Jens Vilstrup, Santoni Rugiu, Eric, Hansen, S. H., Niola, Francesco & Frödin, Morten, 1 Dec 2017, In: Gastroenterology. 153, 6, p. 1662-1673.e10

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Cellular uptake of collagens and implications for immune cell regulation in disease

    Jürgensen, Henrik Jessen, van Putten, Sander Maarten, Nørregaard, Kirstine Sandal, Bugge, T. H., Engelholm, Lars Henning, Behrendt, Niels & Madsen, D. H., 2020, In: Cellular and Molecular Life Sciences. 77, 16, p. 3161-3176

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Collagen density regulates the activity of tumor-infiltrating T cells

    Kuczek, D. E., Larsen, A. M. H., Thorseth, M., Carretta, M., Kalvisa, A., Siersbæk, M. S., Simões, A. M. C., Roslind, A., Engelholm, Lars Henning, Noessner, E., dqp123, dqp123, Svane, Inge Marie, Straten, P. T., Grøntved, L. & Madsen, D. H., 2019, In: Journal for ImmunoTherapy of Cancer. 7, 1, 15 p., 68.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Complementary roles of intracellular and pericellular collagen degradation pathways in vivo

    Wagenaar-Miller, R. A., Engelholm, Lars Henning, Gavard, J., Yamada, S. S., Gutkind, J. S., Behrendt, Niels, Bugge, T. H. & Holmbeck, Kenn, Sep 2007, In: Molecular and Cellular Biology. 27, 18, p. 6309-22 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Complex Determinants in Specific Members of the Mannose Receptor Family Govern Collagen Endocytosis

    Jürgensen, Henrik Jessen, Johansson, K., Madsen, D. H., Porse, A., Melander, M. C., Sørensen, K. R., Nielsen, C., Bugge, T. H., Behrendt, Niels & Engelholm, Lars Henning, 2014, In: The Journal of Biological Chemistry. 289, 11, p. 7935-7947 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Conformational regulation of urokinase receptor function: impact of receptor occupancy and epitope-mapped monoclonal antibodies on lamellipodia induction

    Gårdsvoll, Henrik, Jacobsen, B., Kriegbaum, M. C., Behrendt, Niels, Engelholm, Lars Henning, Østergaard, S. & Ploug, Michael, 23 Sep 2011, In: The Journal of Biological Chemistry. 286, 38, p. 33544-56 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Crystal structures of the ligand-binding region of uPARAP: effect of calcium ion binding

    Yuan, C., Jürgensen, Henrik Jessen, Engelholm, Lars Henning, Li, R., Liu, M., Jiang, L., Luo, Z., Behrendt, Niels & Huang, M., 1 Aug 2016, In: Biochemical Journal. 473, 15, p. 2359-68 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Differential actions of the endocytic collagen receptor uPARAP/Endo180 and the collagenase MMP-2 in bone homeostasis

    Madsen, Daniel Hargbøl, Jürgensen, Henrik Jessen, Ingvarsen, S., Melander, M. C., Albrechtsen, Reidar, Hald, A., Holmbeck, K., Bugge, T. H., Behrendt, Niels & Engelholm, Lars Henning, 2013, In: PloS one. 8, 8, p. e71261

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Differential binding of urokinase and peptide antagonists to the urokinase receptor: evidence from characterization of the receptor in four primate species

    Engelholm, Lars Henning & Behrendt, Niels, Mar 2001, In: Biological Chemistry. 382, 3, p. 435-42 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Differential gene expression in human mammary carcinoma cells: Identification of a new member of a receptor family

    Schiemann, S., Rückels, M., Engelholm, Lars Henning, Schwirzke, M., Brünner, N. & Weidle, U. H., 1997, In: Anticancer Research. 17, 1 A, p. 13-20 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Early reversal cells in adult human bone remodeling: osteoblastic nature, catabolic functions and interactions with osteoclasts

    Abdelgawad, M. E., Delaissé, J., Hinge, M., Jensen, P. R., Alnaimi, R. W., Rolighed, L., Engelholm, Lars Henning, Marcussen, N. & Levin Andersen, T., 2016, In: Histochemistry and Cell Biology. 145, 6, p. 603-615 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation

    Madsen, Daniel Hargbøl, Engelholm, Lars Henning, Ingvarsen, S., Hillig, T., Wagenaar-Miller, R. A., Kjøller, L., Gårdsvoll, Henrik, Høyer-Hansen, G., Holmbeck, Kenn, Bugge, T. H. & Behrendt, Niels, 14 Sep 2007, In: The Journal of Biological Chemistry. 282, 37, p. 27037-45 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Fibroblast growth factor receptor 4 regulates tumor invasion by coupling fibroblast growth factor signaling to extracellular matrix degradation

    Sugiyama, N., Varjosalo, M., Meller, P., Lohi, J., Hyytiäinen, M., Kilpinen, S., Kallioniemi, O., Ingvarsen, S., Engelholm, Lars Henning, Taipale, J., Alitalo, K., Keski-Oja, J. & Lehti, K., 15 Oct 2010, In: Accomplishments in Cancer Research. 70, 20, p. 7851-61 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Gender affects skin wound healing in plasminogen deficient mice

    Rønø, B., Engelholm, Lars Henning, Lund, L. R. & Hald, A., 2013, In: P L o S One. 8, 3, p. e59942

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 9647887