Lars Henning Engelholm
Department of Clinical Medicine
Blegdamsvej 3
2200 2200 København N
Department of Biology
Ole Maaløes Vej 5
2200 2200 København N
- 2007
Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation
Madsen, Daniel Hargbøl, Engelholm, Lars Henning, Ingvarsen, S., Hillig, T., Wagenaar-Miller, R. A., Kjøller, L., Gårdsvoll, Henrik, Høyer-Hansen, G., Holmbeck, Kenn, Bugge, T. H. & Behrendt, Niels, 14 Sep 2007, In: The Journal of Biological Chemistry. 282, 37, p. 27037-45 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Complementary roles of intracellular and pericellular collagen degradation pathways in vivo
Wagenaar-Miller, R. A., Engelholm, Lars Henning, Gavard, J., Yamada, S. S., Gutkind, J. S., Behrendt, Niels, Bugge, T. H. & Holmbeck, Kenn, Sep 2007, In: Molecular and Cellular Biology. 27, 18, p. 6309-22 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased expression of the collagen internalization receptor uPARAP/Endo180 in the stroma of head and neck cancer
Sulek, J., Wagenaar-Miller, R. A., Shireman, J., Molinolo, A., Madsen, Daniel Hargbøl, Engelholm, Lars Henning, Behrendt, Niels & Bugge, T. H., Apr 2007, In: Journal of Histochemistry and Cytochemistry. 55, 4, p. 347-53 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
Intracellular collagen degradation mediated by uPARAP/Endo180 is a major pathway of extracellular matrix turnover during malignancy
Curino, A. C., Engelholm, Lars Henning, Yamada, S. S., Holmbeck, K., Lund, L. R., Molinolo, A. A., Behrendt, Niels, Nielsen, B. S. & Bugge, T. H., 2005, In: Journal of Cell Biology. 169, 6, p. 977-985 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
uPARAP/endo180 directs lysosomal delivery and degradation of collagen IV
Kjøller, L., Engelholm, Lars Henning, Høyer-Hansen, M., Danø, K., Bugge, T. H. & Behrendt, Niels, 1 Feb 2004, In: Experimental Cell Research. 293, 1, p. 106-16 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
- Published
uPARAP/Endo180 is essential for cellular uptake of collagen and promotes fibroblast collagen adhesion
Engelholm, Lars Henning, List, K., Netzel-Arnett, S., Cukierman, E., Mitola, D. J., Aaronson, H., Kjøller, L., Larsen, J. K., Yamada, K. M., Strickland, D. K., Holmbeck, Kenn, Danø, K., Birkedal-Hansen, H., Behrendt, Niels & Bugge, T. H., 31 Mar 2003, In: Journal of Cell Biology. 160, 7, p. 1009-15 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2002
- Published
Matriptase/MT-SP1 is required for postnatal survival, epidermal barrier function, hair follicle development, and thymic homeostasis
List, K., Haudenschild, C. C., Szabo, R., Chen, W., Wahl, S. M., Swaim, W., Engelholm, Lars Henning, Behrendt, Niels & Bugge, T. H., 23 May 2002, In: Oncogene. 21, 23, p. 3765-79 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Urokinase receptor-associated protein (uPARAP) is expressed in connection with malignant as well as benign lesions of the human breast and occurs in specific populations of stromal cells
Schnack Nielsen, B., Rank, F., Engelholm, Lars Henning, Holm, A., Danø, K. & Behrendt, Niels, 10 Apr 2002, In: International Journal of Cancer. Supplement. 98, 5, p. 656-64 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2001
- Published
The urokinase plasminogen activator receptor-associated protein/endo180 is coexpressed with its interaction partners urokinase plasminogen activator receptor and matrix metalloprotease-13 during osteogenesis
Engelholm, Lars Henning, Nielsen, B. S., Netzel-Arnett, S., Solberg, H., Chen, X. D., Lopez Garcia, J. M., López-Otín, C., Young, M. F., Birkedal-Hansen, H., Danø, K., Lund, L. R., Behrendt, Niels & Bugge, T. H., Oct 2001, In: Laboratory Investigation. 81, 10, p. 1403-14 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of two estrogen regulated genes associated with growth regulation of human breast cancer
Ohlsson, H., Brünner, N., Engelholm, Lars Henning, Lundholt, B. K., Weidle, U., Briand, P. & Lykkesfeldt, A. E., 20 Aug 2001, In: Molecular and Cellular Endocrinology. 182, 1, p. 1-11 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 9647887
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Loss of miR-10a activates Lpo and collaborates with activated Wnt signaling in inducing intestinal Neoplasia in female mice
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The collagen receptor uPARAP/Endo180 as a novel target for antibody-drug conjugate mediated treatment of mesenchymal and leukemic cancers
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CRISPR/Cas9 Engineering of Adult Mouse Liver Demonstrates That the Dnajb1–Prkaca Gene Fusion Is Sufficient to Induce Tumors Resembling Fibrolamellar Hepatocellular Carcinoma
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