Claus Storgaard Sørensen

Claus Storgaard Sørensen

Associate Professor, Professor

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    ORCID: 0000-0001-6022-9710

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    1. Published

      ATM/ATR-mediated phosphorylation of PALB2 promotes RAD51 function

      Ahlskog, J. K., Larsen, Brian Daniel, Achanta, K. & Sørensen, Claus Storgaard, May 2016, In: E M B O Reports. 17, 5, p. 671-81 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Deregulation of the RB pathway in human testicular germ cell tumours.

      Bartkova, J., Lukas, C., Sørensen, Claus Storgaard, Meyts, E. R., Skakkebaek, N. E., Lukas, J. & Bartek, J., 2003, In: Journal of Pathology. 200, 2, p. 149-56 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      High-throughput siRNA screens using gammaH2AX as marker uncover key regulators of genome integrity in mammalian cells

      Beck, H., Menzel, T., Syljuåsen, R. G. & Sørensen, Claus Storgaard, 2010, In: Cell Cycle. 9, 12

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Regulators of cyclin-dependent kinases are crucial for maintaining genome integrity in S phase

      Beck, H., Nähse, V., Larsen, Marie Sofie Yoo, Groth, P., Clancy, T., Lees, M., Jørgensen, M., Helleday, T., Syljuåsen, R. G. & Sørensen, Claus Storgaard, 2010, In: Journal of Cell Biology. 188, 5, p. 629-38 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Cyclin-dependent kinase suppression by WEE1 kinase protects the genome through control of replication initiation and nucleotide consumption

      Beck, H., Nähse-Kumpf, V., Larsen, Marie Sofie Yoo, O'Hanlon, K. A., Patzke, S., Holmberg, Christian, Mejlvang, J., Groth, Anja, Nielsen, Olaf, Syljuåsen, R. G. & Sørensen, Claus Storgaard, 2012, In: Molecular and Cellular Biology. 32, 20, p. 4226-4236 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      High-throughput siRNA screens using γH2AX as marker uncover key regulators of genome integrity in mammalian cells

      Beck, H., Menzel, T., Syljuåsen, R. G. & Sørensen, Claus Storgaard, 15 Jun 2010, In: Cell Cycle. 9, 12, p. 2257-2258 2 p.

      Research output: Contribution to journal › Editorial › Research › peer-review

    7. Published

      Synthetic lethal interaction between WEE1 and PKMYT1 is a target for multiple low-dose treatment of high-grade serous ovarian carcinoma

      Benada, Jan, Bulanova, Daria, Azzoni, Violette Iridé Liliane, Petrosius, V., Ghazanfar, S., Wennerberg, Krister & Sørensen, Claus Storgaard, 2023, In: NAR Cancer. 5, 3, 13 p., zcad029.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Self-inflicted DNA breaks in cell differentiation and cancer

      Benada, Jan, Alsowaida, D., Megeney, L. A. & Sørensen, Claus Storgaard, 2023, In: Trends in Cell Biology. 33, 10, p. 850-859

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Overcoming Treatment Toxicity through Sequential Therapy

      Benada, Jan, Ejlertsen, Bent Laursen & Sørensen, Claus Storgaard, 2019, In: Cancer Cell. 35, 6, p. 821-822 2 p.

      Research output: Contribution to journal › Journal article › Research

    10. Published

      Photochemotherapy Induces Interferon Type III Expression via STING Pathway

      Biskup, E., Larsen, Brian Daniel, Rib, Leonor, Folkersen, L., Niazi, O., Kamstrup, M. R. & Sørensen, Claus Storgaard, 2020, In: Cells. 9, 11, p. 1-19

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      A catalog of curated breast cancer genes

      Bose, M., Benada, Jan, Thatte, Jayashree Vijay, Kinalis, S., Ejlertsen, Bent Laursen, Nielsen, Finn Cilius, Sørensen, Claus Storgaard & Rossing, Caroline Maria, 2022, In: Breast Cancer Research and Treatment. 191, p. 431-441

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      FBH1: a new checkpoint factor

      Boyer, A. & Sørensen, Claus Storgaard, 14 Aug 2015, In: OncoTarget. 6, 23, p. 19354-19355 2 p.

      Research output: Contribution to journal › Editorial › Research › peer-review

    13. Published

      DNA replication and cancer: From dysfunctional replication origin activities to therapeutic opportunities

      Boyer, A., Walter, D. & Sørensen, Claus Storgaard, Jun 2016, In: Seminars in Cancer Biology. 37-38, p. 16-25 10 p.

      Research output: Contribution to journal › Review › Research › peer-review

    14. Published

      The PCNA-associated protein PARI negatively regulates homologous recombination via the inhibition of DNA repair synthesis

      Burkovics, P., Dome, L., Juhasz, S., Altmannova, V., Sebesta, M., Pacesa, M., Fugger, K., Sørensen, Claus Storgaard, Lee, M. Y. W. T., Haracska, L. & Krejci, L., 20 Apr 2016, In: Nucleic Acids Research. 44, 7, p. 3176-89 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      LEDGF (p75) promotes DNA-end resection and homologous recombination

      Daugaard, M., Baude, A., Fugger, K., Povlsen, L. K., Beck, H., Sørensen, Claus Storgaard, Petersen, N. H. T., Sorensen, P. H. B., Lukas, Claudia, Bartek, J., Lukas, Jiri, Rohde, M. & Jaattela, Marja, Aug 2012, In: Nature Structural & Molecular Biology. 19, 8, p. 803-810 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Exploiting replicative stress to treat cancer

      Dobbelstein, M. & Sørensen, Claus Storgaard, Jun 2015, In: Nature Reviews. Drug Discovery. 14, 6, p. 405-23 19 p.

      Research output: Contribution to journal › Review › Research › peer-review

    17. Published

      WEE1 kinase limits CDK activities to safeguard DNA replication and mitotic entry

      Elbæk, C. R., Petrosius, V. & Sørensen, Claus Storgaard, 2020, In: Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 819-820, p. 1-6 6 p., 111694.

      Research output: Contribution to journal › Review › Research › peer-review

    18. Published

      WEE1 kinase protects the stability of stalled DNA replication forks by limiting CDK2 activity

      Elbæk, C. R., Petrosius, V., Benada, Jan, Erichsen, L., Damgaard, R. B. & Sørensen, Claus Storgaard, 2022, In: Cell Reports. 38, 3, 110261.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Acute hydroxyurea-induced replication blockade results in replisome components disengagement from nascent DNA without causing fork collapse

      Ercilla, A., Feu, S., Aranda, S., Llopis, A., Brynjólfsdóttir, S. H., Sørensen, Claus Storgaard, Toledo, L. I. & Agell, N., 2020, In: Cellular and molecular life sciences : CMLS. 77, p. 735–749

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      FBH1 co-operates with MUS81 in inducing DNA double-strand breaks and cell death following replication stress

      Fugger, K., Chu, W. K., Haahr, P., Kousholt, A. N., Beck, H., Payne, M. J., Hanada, K., Hickson, Ian David & Sørensen, Claus Storgaard, 2013, In: Nature Communications. 4, p. 1423

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      FBH1 Catalyzes Regression of Stalled Replication Forks

      Fugger, K., Mistrik, M., Neelsen, K. J., Yao, Q., Zellweger, R., Kousholt, A. N., Haahr, Peter Thorlund, Chu, W. K., Bartek, J., Lopes, M., Hickson, Ian David & Sørensen, Claus Storgaard, 10 Mar 2015, In: Cell Reports.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing

      Galanos, P., Vougas, K., Walter, D., Polyzos, A., Maya-Mendoza, A., Haagensen, E. J., Kokkalis, A., Roumelioti, F-M., Gagos, S., Tzetis, M., Canovas, B., Igea, A., Ahuja, A. K., Zellweger, R., Havaki, S., Kanavakis, E., Kletsas, D., Roninson, I. B., Garbis, S. D., Lopes, M. & 7 others, Nebreda, A., Thanos, D., Blow, J. J., Townsend, P., Sørensen, Claus Storgaard, Bartek, J. & Gorgoulis, V. G., Jul 2016, In: Nature Cell Biology. 18, 7, p. 777-89 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability

      Galanos, P., Pappas, G., Polyzos, A., Kotsinas, A., Svolaki, I., Giakoumakis, N. N., Glytsou, C., Pateras, I. S., Swain, U., Souliotis, V. L., Georgakilas, A. G., Geacintov, N., Scorrano, L., Lukas, C., Lukas, J., Livneh, Z., Lygerou, Z., Chowdhury, D., Sørensen, C. S., Bartek, J. & 1 others, Gorgoulis, V. G., 2018, In: Genome Biology (Online Edition). 19, p. 1-18 37.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation.

      Gatei, M., Sloper, K., Sørensen, Claus Storgaard, Syljuäsen, R., Falck, J., Hobson, K., Savage, K., Lukas, J., Zhou, B., Bartek, J. & Khanna, K. K., 2003, In: Journal of Biological Chemistry. 278, 17, p. 14806-11 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Formate overflow drives toxic folate trapping in MTHFD1 inhibited cancer cells

      Green, A. C., Marttila, P., Kiweler, N., Chalkiadaki, C., Wiita, E., Cookson, V., Lesur, A., Eiden, K., Bernardin, F., Vallin, K. S. A., Borhade, S., Long, M., Ghahe, E. K., Jiménez-Alonso, J. J., Jemth, A-S., Loseva, O., Mortusewicz, O., Meyers, M., Viry, E., Johansson, A. I. & 14 others, Hodek, O., Homan, E., Bonagas, N., Ramos, L., Sandberg, L., Frödin, Morten, Moussay, E., Slipicevic, A., Letellier, E., Paggetti, J., Sørensen, Claus Storgaard, Helleday, T., Henriksson, M. & Meiser, J., 2023, In: Nature Metabolism. 5, p. 642-659

      Research output: Contribution to journal › Journal article › Research › peer-review

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