Claus Storgaard Sørensen

Claus Storgaard Sørensen

Associate Professor, Professor

Member of:


    1. 1990
    2. Echocardiography in the initial assessment of patients with small cell lung cancer

      Mackintosh, J. F., Hawson, G. A. T. & Sørensen, Claus Storgaard, 1 Jan 1990, In: Cancer Journal. 3, 5, p. 248-251 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. 1999
    4. Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex.

      Lukas, C., Sørensen, Claus Storgaard, Kramer, E., Santoni Rugiu, Eric, Lindeneg, C., Peters, J. M., Bartek, J. & Lukas, J., 1999, In: Nature. 401, 6755, p. 815-8 3 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization.

      Petersen, B. O., Lukas, J., Sørensen, Claus Storgaard, Bartek, J. & Helin, K., 1999, In: EMBO Journal. 18, 2, p. 396-410 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      p16INK4a, but not constitutively active pRb, can impose a sustained G1 arrest: molecular mechanisms and implications for oncogenesis.

      Lukas, J., Sørensen, Claus Storgaard, Lukas, C., Santoni Rugiu, Eric & Bartek, J., 1999, In: Oncogene. 18, 27, p. 3930-5 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. 2000
    8. Published

      Nonperiodic activity of the human anaphase-promoting complex-Cdh1 ubiquitin ligase results in continuous DNA synthesis uncoupled from mitosis.

      Lukas, C., Kramer, E. R., Peters, J. M., Bartek, J., Lukas, J. & Sørensen, Claus Storgaard, 2000, In: Molecular and Cellular Biology. 20, 20, p. 7613-23 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. 2001
    10. Published

      A conserved cyclin-binding domain determines functional interplay between anaphase-promoting complex-Cdh1 and cyclin A-Cdk2 during cell cycle progression.

      Lukas, C., Kramer, E. R., Peters, J. M., Bartek, J., Lukas, J. & Sørensen, Claus Storgaard, 2001, In: Molecular and Cellular Biology. 21, 11, p. 3692-703 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. 2002
    12. Published

      E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC(Cdh1).

      Hsu, J. Y., Reimann, J. D. R., Sørensen, Claus Storgaard, Lukas, J. & Jackson, P. K., 2002, In: Nature Cell Biology. 4, 5, p. 358-66 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. 2003
    14. Published

      Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation.

      Gatei, M., Sloper, K., Sørensen, Claus Storgaard, Syljuäsen, R., Falck, J., Hobson, K., Savage, K., Lukas, J., Zhou, B., Bartek, J. & Khanna, K. K., 2003, In: Journal of Biological Chemistry. 278, 17, p. 14806-11 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A.

      Sørensen, Claus Storgaard, Syljuåsen, R. G., Falck, J., Schroeder, T., Rönnstrand, L., Khanna, K. K., Zhou, B., Bartek, J. & Lukas, J., 2003, In: Cancer Cell. 3, 3, p. 247-58 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      DNA repair rate and etoposide (VP16) resistance of tumor cell subpopulations derived from a single human small cell lung cancer.

      Hansen, L. T., Lundin, C., Helleday, T., Poulsen, H. S., Sørensen, Claus Storgaard, Petersen, L. N. & Spang-Thomsen, M., 2003, In: Lung Cancer. 40, 2, p. 157-64 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Deregulation of the RB pathway in human testicular germ cell tumours.

      Bartkova, J., Lukas, C., Sørensen, Claus Storgaard, Meyts, E. R., Skakkebaek, N. E., Lukas, J. & Bartek, J., 2003, In: Journal of Pathology. 200, 2, p. 149-56 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. 2004
    19. Published

      ATR, Claspin and the Rad9-Rad1-Hus1 complex regulate Chk1 and Cdc25A in the absence of DNA damage.

      Sørensen, Claus Storgaard, Syljuåsen, R. G., Lukas, J. & Bartek, J., 2004, In: Cell Cycle. 3, 7, p. 941-5 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      Inhibition of Chk1 by CEP-3891 accelerates mitotic nuclear fragmentation in response to ionizing Radiation.

      Syljuåsen, R. G., Sørensen, Claus Storgaard, Nylandsted, J., Lukas, C., Lukas, J. & Bartek, J., 2004, In: Cancer Research. 64, 24, p. 9035-40 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. 2005
    22. Published

      Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage.

      Syljuåsen, R. G., Sørensen, Claus Storgaard, Hansen, L. T., Fugger, K., Lundin, C., Johansson, F., Helleday, T., Sehested, M., Lukas, J. & Bartek, J., 2005, In: Molecular and Cellular Biology. 25, 9, p. 3553-62 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Published

      The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair.

      Sørensen, Claus Storgaard, Hansen, L. T., Dziegielewski, J., Syljuåsen, R. G., Lundin, C., Bartek, J. & Helleday, T., 2005, In: Nature Cell Biology. 7, 2, p. 195-201 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. 2007
    25. Published

      RPA mediates recombination repair during replication stress and is displaced from DNA by checkpoint signalling in human cells.

      Sleeth, K. M., Sørensen, Claus Storgaard, Issaeva, N., Dziegielewski, J., Bartek, J. & Helleday, T., 2007, In: Journal of Molecular Biology. 373, 1, p. 38-47 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. 2008
    27. Published

      The histone methyltransferase SET8 is required for S-phase progression.

      Jørgensen, S., Elvers, I., Trelle, M. B., Menzel, T., Eskildsen, M., Jensen, O. N., Helleday, T., Helin, K. & Sørensen, Claus Storgaard, 2008, In: Journal of Cell Biology. 179, 7, p. 1337-45 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. 2009
    29. Published

      NEK11 regulates CDC25A degradation and the IR-induced G2/M checkpoint

      Melixetian, M., Helin, K., Klein, D. K. & Sørensen, Claus Storgaard, 1 Jan 2009, In: Nature Cell Biology. 11, 10, p. 1247-1253 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    30. 2010
    31. Published

      High-throughput siRNA screens using gammaH2AX as marker uncover key regulators of genome integrity in mammalian cells

      Beck, H., Menzel, T., Syljuåsen, R. G. & Sørensen, Claus Storgaard, 2010, In: Cell Cycle. 9, 12

      Research output: Contribution to journalJournal articleResearchpeer-review

    32. Published

      NEK11: linking CHK1 and CDC25A in DNA damage checkpoint signaling

      Sørensen, Claus Storgaard, Melixetian, M., Klein, D. K. & Helin, K., 2010, In: Cell Cycle. 9, 3, p. 450-5 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    33. Published

      Regulators of cyclin-dependent kinases are crucial for maintaining genome integrity in S phase

      Beck, H., Nähse, V., Larsen, Marie Sofie Yoo, Groth, P., Clancy, T., Lees, M., Jørgensen, M., Helleday, T., Syljuåsen, R. G. & Sørensen, Claus Storgaard, 2010, In: Journal of Cell Biology. 188, 5, p. 629-38 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    34. Published

      High-throughput siRNA screens using γH2AX as marker uncover key regulators of genome integrity in mammalian cells

      Beck, H., Menzel, T., Syljuåsen, R. G. & Sørensen, Claus Storgaard, 15 Jun 2010, In: Cell Cycle. 9, 12, p. 2257-2258 2 p.

      Research output: Contribution to journalEditorialResearchpeer-review

    35. 2011
    36. Published

      A genetic screen identifies BRCA2 and PALB2 as key regulators of G2 checkpoint maintenance

      Menzel, T., Nähse-Kumpf, V., Kousholt, A. N., Klein, D. K., Lund-Andersen, C., Lees, M., Johansen, Jens Vilstrup, Syljuåsen, R. G. & Sørensen, Claus Storgaard, 1 Jan 2011, In: E M B O Reports. 12, 7, p. 705-12 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    37. Published

      SET8 is degraded via PCNA-coupled CRL4(CDT2) ubiquitylation in S phase and after UV irradiation

      Jørgensen, S., Eskildsen, M., Fugger, K., Hansen, L., Larsen, Marie Sofie Yoo, Kousholt, A. N., Syljuåsen, R. G., Trelle, M. B., Jensen, O. N., Helin, K. & Sørensen, Claus Storgaard, 10 Jan 2011, In: Journal of Cell Biology. 192, 1, p. 43-54 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    38. 2012
    39. Published

      CtIP-dependent DNA resection is required for DNA damage checkpoint maintenance but not initiation

      Kousholt, A. N., Fugger, K., Hoffmann, S., Larsen, Brian Daniel, Menzel, T., Sartori, A. A. & Sørensen, Claus Storgaard, 2012, In: Journal of Cell Biology. 197, 7, p. 869-76 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

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    ID: 10867