Claus Storgaard Sørensen

Claus Storgaard Sørensen

Associate Professor, Professor

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    ORCID: 0000-0001-6022-9710

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    1. Published

      PALB2-mutated human mammary cells display a broad spectrum of morphological and functional abnormalities induced by increased TGFβ signaling

      Tuppurainen, H., Laurila, N., Nätynki, M., Eshraghi, L., Tervasmäki, A., Erichsen, L., Sørensen, Claus Storgaard, Pylkäs, K., Winqvist, R. & Peltoketo, H., 2024, In: Cellular and Molecular Life Sciences. 81, 21 p., 173.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      A catalog of curated breast cancer genes

      Bose, M., Benada, Jan, Thatte, Jayashree Vijay, Kinalis, S., Ejlertsen, Bent Laursen, Nielsen, Finn Cilius, Sørensen, Claus Storgaard & Rossing, Caroline Maria, 2022, In: Breast Cancer Research and Treatment. 191, p. 431-441

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      A conserved cyclin-binding domain determines functional interplay between anaphase-promoting complex-Cdh1 and cyclin A-Cdk2 during cell cycle progression.

      Lukas, C., Kramer, E. R., Peters, J. M., Bartek, J., Lukas, J. & Sørensen, Claus Storgaard, 2001, In: Molecular and Cellular Biology. 21, 11, p. 3692-703 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      A genetic screen identifies BRCA2 and PALB2 as key regulators of G2 checkpoint maintenance

      Menzel, T., Nähse-Kumpf, V., Kousholt, A. N., Klein, D. K., Lund-Andersen, C., Lees, M., Johansen, Jens Vilstrup, Syljuåsen, R. G. & Sørensen, Claus Storgaard, 1 Jan 2011, In: E M B O Reports. 12, 7, p. 705-12 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      ADAM12 expression is upregulated in cancer cells upon radiation and constitutes a prognostic factor in rectal cancer patients following radiotherapy

      Piotrowski, Kris, Puig Blasco, Laia, Samsøe-Petersen, Jacob, Eefsen, R. L., Illemann, M., Oria, Victor Oginga, Campos, K. I. A., Lopresti, Alexia Mélanie, Albrechtsen, Reidar, Sørensen, Claus Storgaard, Sun, X. F., Kveiborg, Marie & Gnosa, S., 2023, In: Cancer Gene Therapy. 30, p. 1369-1381 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      ATM/ATR-mediated phosphorylation of PALB2 promotes RAD51 function

      Ahlskog, J. K., Larsen, Brian Daniel, Achanta, K. & Sørensen, Claus Storgaard, May 2016, In: E M B O Reports. 17, 5, p. 671-81 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      ATR, Claspin and the Rad9-Rad1-Hus1 complex regulate Chk1 and Cdc25A in the absence of DNA damage.

      Sørensen, Claus Storgaard, Syljuåsen, R. G., Lukas, J. & Bartek, J., 2004, In: Cell Cycle. 3, 7, p. 941-5 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex.

      Lukas, C., Sørensen, Claus Storgaard, Kramer, E., Santoni Rugiu, Eric, Lindeneg, C., Peters, J. M., Bartek, J. & Lukas, J., 1999, In: Nature. 401, 6755, p. 815-8 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Acute hydroxyurea-induced replication blockade results in replisome components disengagement from nascent DNA without causing fork collapse

      Ercilla, A., Feu, S., Aranda, S., Llopis, A., Brynjólfsdóttir, S. H., Sørensen, Claus Storgaard, Toledo, L. I. & Agell, N., 2020, In: Cellular and molecular life sciences : CMLS. 77, p. 735–749

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation.

      Gatei, M., Sloper, K., Sørensen, Claus Storgaard, Syljuäsen, R., Falck, J., Hobson, K., Savage, K., Lukas, J., Zhou, B., Bartek, J. & Khanna, K. K., 2003, In: Journal of Biological Chemistry. 278, 17, p. 14806-11 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Cancer cells use self-inflicted DNA breaks to evade growth limits imposed by genotoxic stress

      Larsen, Brian Daniel, Benada, Jan, Yung, P. Y. K., Bell, R. A. V., Pappas, G., Urban, V., Ahlskog, J. K., Kuo, T. T., Janscak, P., Megeney, L. A., Elsässer, S. J., Bartek, J. & Sørensen, Claus Storgaard, 2022, In: Science. 376, 6592, p. 476-483 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A.

      Sørensen, Claus Storgaard, Syljuåsen, R. G., Falck, J., Schroeder, T., Rönnstrand, L., Khanna, K. K., Zhou, B., Bartek, J. & Lukas, J., 2003, In: Cancer Cell. 3, 3, p. 247-58 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Chromatin Landscaping At Mitotic Exit Orchestrates Genome Function

      Shoaib, Muhammad, Nair, Nidhi & Sørensen, Claus Storgaard, 2020, In: Frontiers in Genetics. 11, p. 1-9 103.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Chromatin dynamics in genome stability: Roles in suppressing endogenous DNA damage and facilitating DNA repair

      Nair, Nidhi, Shoaib, Muhammad & Sørensen, Claus Storgaard, 10 Jul 2017, In: International Journal of Molecular Sciences. 18, 7, 21 p., 1486.

      Research output: Contribution to journal › Review › Research › peer-review

    15. Published

      Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing

      Galanos, P., Vougas, K., Walter, D., Polyzos, A., Maya-Mendoza, A., Haagensen, E. J., Kokkalis, A., Roumelioti, F-M., Gagos, S., Tzetis, M., Canovas, B., Igea, A., Ahuja, A. K., Zellweger, R., Havaki, S., Kanavakis, E., Kletsas, D., Roninson, I. B., Garbis, S. D., Lopes, M. & 7 others, Nebreda, A., Thanos, D., Blow, J. J., Townsend, P., Sørensen, Claus Storgaard, Bartek, J. & Gorgoulis, V. G., Jul 2016, In: Nature Cell Biology. 18, 7, p. 777-89 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      CtIP-dependent DNA resection is required for DNA damage checkpoint maintenance but not initiation

      Kousholt, A. N., Fugger, K., Hoffmann, S., Larsen, Brian Daniel, Menzel, T., Sartori, A. A. & Sørensen, Claus Storgaard, 2012, In: Journal of Cell Biology. 197, 7, p. 869-76 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Cyclin F suppresses B-Myb activity to promote cell cycle checkpoint control

      Klein, D. K., Hoffmann, Saskia, Ahlskog, J. K., O'Hanlon, K., Quaas, M., Larsen, Brian Daniel, Rolland, B., Rösner, Heike Ilona, Walter, D., Kousholt, A. N., Menzel, T., Lees, M., Johansen, Jens Vilstrup, Rappsilber, J., Engeland, K. & Sørensen, Claus Storgaard, 2015, In: Nature Communications. 6, p. 5800

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Cyclin-dependent kinase suppression by WEE1 kinase protects the genome through control of replication initiation and nucleotide consumption

      Beck, H., Nähse-Kumpf, V., Larsen, Marie Sofie Yoo, O'Hanlon, K. A., Patzke, S., Holmberg, Christian, Mejlvang, J., Groth, Anja, Nielsen, Olaf, Syljuåsen, R. G. & Sørensen, Claus Storgaard, 2012, In: Molecular and Cellular Biology. 32, 20, p. 4226-4236 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      DNA binding and RAD51 engagement by the BRCA2 C-terminus orchestrate DNA repair and replication fork preservation

      Kwon, Y., Rösner, H., Zhao, W., Selemenakis, P., He, Z., Kawale, A. S., Katz, J. N., Rogers, C. M., Neal, F. E., Badamchi Shabestari, A., Petrosius, V., Singh, A. K., Joel, M. Z., Lu, L., Holloway, S. P., Burma, S., Mukherjee, B., Hromas, R., Mazin, A., Wiese, C. & 2 others, Sørensen, Claus Storgaard & Sung, P., 2023, In: Nature Communications. 14, 18 p., 432.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      DNA repair rate and etoposide (VP16) resistance of tumor cell subpopulations derived from a single human small cell lung cancer.

      Hansen, L. T., Lundin, C., Helleday, T., Poulsen, H. S., Sørensen, Claus Storgaard, Petersen, L. N. & Spang-Thomsen, M., 2003, In: Lung Cancer. 40, 2, p. 157-64 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      DNA replication and cancer: From dysfunctional replication origin activities to therapeutic opportunities

      Boyer, A., Walter, D. & Sørensen, Claus Storgaard, Jun 2016, In: Seminars in Cancer Biology. 37-38, p. 16-25 10 p.

      Research output: Contribution to journal › Review › Research › peer-review

    22. Published

      Damage-induced DNA replication stalling relies on MAPK-activated protein kinase 2 activity

      Köpper, F., Bierwirth, C., Schön, M., Kunze, M., Elvers, I., Kranz, D., Saini, P., Menon, M. B., Walter, D., Sørensen, Claus Storgaard, Gaestel, M., Helleday, T., Schön, M. P. & Dobbelstein, M., 15 Oct 2013, In: PNAS Early Edition. 110, 42, p. 16856-61 6 p.

      Research output: Contribution to journal › Journal article › Research

    23. Published

      Deregulation of the RB pathway in human testicular germ cell tumours.

      Bartkova, J., Lukas, C., Sørensen, Claus Storgaard, Meyts, E. R., Skakkebaek, N. E., Lukas, J. & Bartek, J., 2003, In: Journal of Pathology. 200, 2, p. 149-56 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      E2F transcription regulation: an orphan cyclin enters the stage

      Rösner, Heike Ilona & Sørensen, Claus Storgaard, 2019, In: The EMBO Journal. 38, 20, e103421.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC(Cdh1).

      Hsu, J. Y., Reimann, J. D. R., Sørensen, Claus Storgaard, Lukas, J. & Jackson, P. K., 2002, In: Nature Cell Biology. 4, 5, p. 358-66 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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