Claus Storgaard Sørensen
Associate Professor, Professor
Sørensen Group
Ole Maaløes Vej 5, 2200 København N.
Member of:
- 2010
- Published
High-throughput siRNA screens using γH2AX as marker uncover key regulators of genome integrity in mammalian cells
Beck, H., Menzel, T., Syljuåsen, R. G. & Sørensen, Claus Storgaard, 15 Jun 2010, In: Cell Cycle. 9, 12, p. 2257-2258 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
High-throughput siRNA screens using gammaH2AX as marker uncover key regulators of genome integrity in mammalian cells
Beck, H., Menzel, T., Syljuåsen, R. G. & Sørensen, Claus Storgaard, 2010, In: Cell Cycle. 9, 12Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NEK11: linking CHK1 and CDC25A in DNA damage checkpoint signaling
Sørensen, Claus Storgaard, Melixetian, M., Klein, D. K. & Helin, K., 2010, In: Cell Cycle. 9, 3, p. 450-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulators of cyclin-dependent kinases are crucial for maintaining genome integrity in S phase
Beck, H., Nähse, V., Larsen, Marie Sofie Yoo, Groth, P., Clancy, T., Lees, M., Jørgensen, M., Helleday, T., Syljuåsen, R. G. & Sørensen, Claus Storgaard, 2010, In: Journal of Cell Biology. 188, 5, p. 629-38 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
NEK11 regulates CDC25A degradation and the IR-induced G2/M checkpoint
Melixetian, M., Helin, K., Klein, D. K. & Sørensen, Claus Storgaard, 1 Jan 2009, In: Nature Cell Biology. 11, 10, p. 1247-1253 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
The histone methyltransferase SET8 is required for S-phase progression.
Jørgensen, S., Elvers, I., Trelle, M. B., Menzel, T., Eskildsen, M., Jensen, O. N., Helleday, T., Helin, K. & Sørensen, Claus Storgaard, 2008, In: Journal of Cell Biology. 179, 7, p. 1337-45 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
RPA mediates recombination repair during replication stress and is displaced from DNA by checkpoint signalling in human cells.
Sleeth, K. M., Sørensen, Claus Storgaard, Issaeva, N., Dziegielewski, J., Bartek, J. & Helleday, T., 2007, In: Journal of Molecular Biology. 373, 1, p. 38-47 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage.
Syljuåsen, R. G., Sørensen, Claus Storgaard, Hansen, L. T., Fugger, K., Lundin, C., Johansson, F., Helleday, T., Sehested, M., Lukas, J. & Bartek, J., 2005, In: Molecular and Cellular Biology. 25, 9, p. 3553-62 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair.
Sørensen, Claus Storgaard, Hansen, L. T., Dziegielewski, J., Syljuåsen, R. G., Lundin, C., Bartek, J. & Helleday, T., 2005, In: Nature Cell Biology. 7, 2, p. 195-201 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
ATR, Claspin and the Rad9-Rad1-Hus1 complex regulate Chk1 and Cdc25A in the absence of DNA damage.
Sørensen, Claus Storgaard, Syljuåsen, R. G., Lukas, J. & Bartek, J., 2004, In: Cell Cycle. 3, 7, p. 941-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of Chk1 by CEP-3891 accelerates mitotic nuclear fragmentation in response to ionizing Radiation.
Syljuåsen, R. G., Sørensen, Claus Storgaard, Nylandsted, J., Lukas, C., Lukas, J. & Bartek, J., 2004, In: Cancer Research. 64, 24, p. 9035-40 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
- Published
Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation.
Gatei, M., Sloper, K., Sørensen, Claus Storgaard, Syljuäsen, R., Falck, J., Hobson, K., Savage, K., Lukas, J., Zhou, B., Bartek, J. & Khanna, K. K., 2003, In: Journal of Biological Chemistry. 278, 17, p. 14806-11 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A.
Sørensen, Claus Storgaard, Syljuåsen, R. G., Falck, J., Schroeder, T., Rönnstrand, L., Khanna, K. K., Zhou, B., Bartek, J. & Lukas, J., 2003, In: Cancer Cell. 3, 3, p. 247-58 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DNA repair rate and etoposide (VP16) resistance of tumor cell subpopulations derived from a single human small cell lung cancer.
Hansen, L. T., Lundin, C., Helleday, T., Poulsen, H. S., Sørensen, Claus Storgaard, Petersen, L. N. & Spang-Thomsen, M., 2003, In: Lung Cancer. 40, 2, p. 157-64 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deregulation of the RB pathway in human testicular germ cell tumours.
Bartkova, J., Lukas, C., Sørensen, Claus Storgaard, Meyts, E. R., Skakkebaek, N. E., Lukas, J. & Bartek, J., 2003, In: Journal of Pathology. 200, 2, p. 149-56 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2002
- Published
E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC(Cdh1).
Hsu, J. Y., Reimann, J. D. R., Sørensen, Claus Storgaard, Lukas, J. & Jackson, P. K., 2002, In: Nature Cell Biology. 4, 5, p. 358-66 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2001
- Published
A conserved cyclin-binding domain determines functional interplay between anaphase-promoting complex-Cdh1 and cyclin A-Cdk2 during cell cycle progression.
Lukas, C., Kramer, E. R., Peters, J. M., Bartek, J., Lukas, J. & Sørensen, Claus Storgaard, 2001, In: Molecular and Cellular Biology. 21, 11, p. 3692-703 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2000
- Published
Nonperiodic activity of the human anaphase-promoting complex-Cdh1 ubiquitin ligase results in continuous DNA synthesis uncoupled from mitosis.
Lukas, C., Kramer, E. R., Peters, J. M., Bartek, J., Lukas, J. & Sørensen, Claus Storgaard, 2000, In: Molecular and Cellular Biology. 20, 20, p. 7613-23 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1999
Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex.
Lukas, C., Sørensen, Claus Storgaard, Kramer, E., Santoni Rugiu, Eric, Lindeneg, C., Peters, J. M., Bartek, J. & Lukas, J., 1999, In: Nature. 401, 6755, p. 815-8 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization.
Petersen, B. O., Lukas, J., Sørensen, Claus Storgaard, Bartek, J. & Helin, K., 1999, In: EMBO Journal. 18, 2, p. 396-410 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
p16INK4a, but not constitutively active pRb, can impose a sustained G1 arrest: molecular mechanisms and implications for oncogenesis.
Lukas, J., Sørensen, Claus Storgaard, Lukas, C., Santoni Rugiu, Eric & Bartek, J., 1999, In: Oncogene. 18, 27, p. 3930-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1990
Echocardiography in the initial assessment of patients with small cell lung cancer
Mackintosh, J. F., Hawson, G. A. T. & Sørensen, Claus Storgaard, 1 Jan 1990, In: Cancer Journal. 3, 5, p. 248-251 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 10867
Most downloads
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338
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Chromatin dynamics in genome stability: Roles in suppressing endogenous DNA damage and facilitating DNA repair
Research output: Contribution to journal › Review › Research › peer-review
Published -
244
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Histone H4K20 methylation mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
175
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Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability
Research output: Contribution to journal › Journal article › Research › peer-review
Published