Claus Storgaard Sørensen

Claus Storgaard Sørensen

Associate Professor, Professor

Member of:


    1. 2010
    2. Published

      High-throughput siRNA screens using γH2AX as marker uncover key regulators of genome integrity in mammalian cells

      Beck, H., Menzel, T., Syljuåsen, R. G. & Sørensen, Claus Storgaard, 15 Jun 2010, In: Cell Cycle. 9, 12, p. 2257-2258 2 p.

      Research output: Contribution to journalEditorialResearchpeer-review

    3. Published

      High-throughput siRNA screens using gammaH2AX as marker uncover key regulators of genome integrity in mammalian cells

      Beck, H., Menzel, T., Syljuåsen, R. G. & Sørensen, Claus Storgaard, 2010, In: Cell Cycle. 9, 12

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      NEK11: linking CHK1 and CDC25A in DNA damage checkpoint signaling

      Sørensen, Claus Storgaard, Melixetian, M., Klein, D. K. & Helin, K., 2010, In: Cell Cycle. 9, 3, p. 450-5 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      Regulators of cyclin-dependent kinases are crucial for maintaining genome integrity in S phase

      Beck, H., Nähse, V., Larsen, Marie Sofie Yoo, Groth, P., Clancy, T., Lees, M., Jørgensen, M., Helleday, T., Syljuåsen, R. G. & Sørensen, Claus Storgaard, 2010, In: Journal of Cell Biology. 188, 5, p. 629-38 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. 2009
    7. Published

      NEK11 regulates CDC25A degradation and the IR-induced G2/M checkpoint

      Melixetian, M., Helin, K., Klein, D. K. & Sørensen, Claus Storgaard, 1 Jan 2009, In: Nature Cell Biology. 11, 10, p. 1247-1253 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. 2008
    9. Published

      The histone methyltransferase SET8 is required for S-phase progression.

      Jørgensen, S., Elvers, I., Trelle, M. B., Menzel, T., Eskildsen, M., Jensen, O. N., Helleday, T., Helin, K. & Sørensen, Claus Storgaard, 2008, In: Journal of Cell Biology. 179, 7, p. 1337-45 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. 2007
    11. Published

      RPA mediates recombination repair during replication stress and is displaced from DNA by checkpoint signalling in human cells.

      Sleeth, K. M., Sørensen, Claus Storgaard, Issaeva, N., Dziegielewski, J., Bartek, J. & Helleday, T., 2007, In: Journal of Molecular Biology. 373, 1, p. 38-47 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. 2005
    13. Published

      Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage.

      Syljuåsen, R. G., Sørensen, Claus Storgaard, Hansen, L. T., Fugger, K., Lundin, C., Johansson, F., Helleday, T., Sehested, M., Lukas, J. & Bartek, J., 2005, In: Molecular and Cellular Biology. 25, 9, p. 3553-62 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair.

      Sørensen, Claus Storgaard, Hansen, L. T., Dziegielewski, J., Syljuåsen, R. G., Lundin, C., Bartek, J. & Helleday, T., 2005, In: Nature Cell Biology. 7, 2, p. 195-201 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. 2004
    16. Published

      ATR, Claspin and the Rad9-Rad1-Hus1 complex regulate Chk1 and Cdc25A in the absence of DNA damage.

      Sørensen, Claus Storgaard, Syljuåsen, R. G., Lukas, J. & Bartek, J., 2004, In: Cell Cycle. 3, 7, p. 941-5 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Inhibition of Chk1 by CEP-3891 accelerates mitotic nuclear fragmentation in response to ionizing Radiation.

      Syljuåsen, R. G., Sørensen, Claus Storgaard, Nylandsted, J., Lukas, C., Lukas, J. & Bartek, J., 2004, In: Cancer Research. 64, 24, p. 9035-40 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. 2003
    19. Published

      Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation.

      Gatei, M., Sloper, K., Sørensen, Claus Storgaard, Syljuäsen, R., Falck, J., Hobson, K., Savage, K., Lukas, J., Zhou, B., Bartek, J. & Khanna, K. K., 2003, In: Journal of Biological Chemistry. 278, 17, p. 14806-11 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A.

      Sørensen, Claus Storgaard, Syljuåsen, R. G., Falck, J., Schroeder, T., Rönnstrand, L., Khanna, K. K., Zhou, B., Bartek, J. & Lukas, J., 2003, In: Cancer Cell. 3, 3, p. 247-58 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. Published

      DNA repair rate and etoposide (VP16) resistance of tumor cell subpopulations derived from a single human small cell lung cancer.

      Hansen, L. T., Lundin, C., Helleday, T., Poulsen, H. S., Sørensen, Claus Storgaard, Petersen, L. N. & Spang-Thomsen, M., 2003, In: Lung Cancer. 40, 2, p. 157-64 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      Deregulation of the RB pathway in human testicular germ cell tumours.

      Bartkova, J., Lukas, C., Sørensen, Claus Storgaard, Meyts, E. R., Skakkebaek, N. E., Lukas, J. & Bartek, J., 2003, In: Journal of Pathology. 200, 2, p. 149-56 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. 2002
    24. Published

      E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC(Cdh1).

      Hsu, J. Y., Reimann, J. D. R., Sørensen, Claus Storgaard, Lukas, J. & Jackson, P. K., 2002, In: Nature Cell Biology. 4, 5, p. 358-66 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. 2001
    26. Published

      A conserved cyclin-binding domain determines functional interplay between anaphase-promoting complex-Cdh1 and cyclin A-Cdk2 during cell cycle progression.

      Lukas, C., Kramer, E. R., Peters, J. M., Bartek, J., Lukas, J. & Sørensen, Claus Storgaard, 2001, In: Molecular and Cellular Biology. 21, 11, p. 3692-703 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. 2000
    28. Published

      Nonperiodic activity of the human anaphase-promoting complex-Cdh1 ubiquitin ligase results in continuous DNA synthesis uncoupled from mitosis.

      Lukas, C., Kramer, E. R., Peters, J. M., Bartek, J., Lukas, J. & Sørensen, Claus Storgaard, 2000, In: Molecular and Cellular Biology. 20, 20, p. 7613-23 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. 1999
    30. Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex.

      Lukas, C., Sørensen, Claus Storgaard, Kramer, E., Santoni Rugiu, Eric, Lindeneg, C., Peters, J. M., Bartek, J. & Lukas, J., 1999, In: Nature. 401, 6755, p. 815-8 3 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    31. Published

      Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization.

      Petersen, B. O., Lukas, J., Sørensen, Claus Storgaard, Bartek, J. & Helin, K., 1999, In: EMBO Journal. 18, 2, p. 396-410 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    32. Published

      p16INK4a, but not constitutively active pRb, can impose a sustained G1 arrest: molecular mechanisms and implications for oncogenesis.

      Lukas, J., Sørensen, Claus Storgaard, Lukas, C., Santoni Rugiu, Eric & Bartek, J., 1999, In: Oncogene. 18, 27, p. 3930-5 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    33. 1990
    34. Echocardiography in the initial assessment of patients with small cell lung cancer

      Mackintosh, J. F., Hawson, G. A. T. & Sørensen, Claus Storgaard, 1 Jan 1990, In: Cancer Journal. 3, 5, p. 248-251 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

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