Henrik Jessen Jürgensen

Henrik Jessen Jürgensen


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  1. 2022
  2. Published

    The endocytic receptor uPARAP is a regulator of extracellular thrombospondin-1

    Nørregaard, Kirstine Sandal, Jürgensen, Henrik Jessen, Ingvarsen, S. Z., Heltberg, S. S., Hagensen, C. E., Gårdsvoll, Henrik, Madsen, D. H., Jensen, O. N., Engelholm, Lars Henning & Behrendt, Niels, 2022, In: Matrix Biology. 111, p. 307-328 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Uncovering mediators of collagen degradation in the tumor microenvironment

    Thorseth, M. L., Carretta, M., Jensen, C., Mølgaard, K., Jürgensen, Henrik Jessen, Engelholm, Lars Henning, Behrendt, Niels, Willumsen, N. & Madsen, Daniel Hargbøl, 2022, In: Matrix Biology Plus. 13, 100101.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. 2021
  5. Published

    Osteosarcoma and metastasis associated bone degradation—a tale of osteoclast and malignant cell cooperativity

    Nørregaard, Kirstine Sandal, Jürgensen, Henrik Jessen, Gårdsvoll, Henrik, Engelholm, Lars Henning, Behrendt, Niels & Søe, K., 2021, In: International Journal of Molecular Sciences. 22, 13, 6865.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    The Collagen Receptor uPARAP in Malignant Mesothelioma: A Potential Diagnostic Marker and Therapeutic Target

    Cakilkaya, Pinar, Sørensen, R. R., Jürgensen, Henrik Jessen, Krigslund, O., Gårdsvoll, Henrik, Nielsen, C. F., Santoni Rugiu, Eric, Behrendt, Niels & Engelholm, Lars Henning, 2021, In: International Journal of Molecular Sciences. 22, 21, 17 p., 11452.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. 2020
  8. Published

    Cellular uptake of collagens and implications for immune cell regulation in disease

    Jürgensen, Henrik Jessen, van Putten, Sander Maarten, Nørregaard, Kirstine Sandal, Bugge, T. H., Engelholm, Lars Henning, Behrendt, Niels & Madsen, D. H., 2020, In: Cellular and Molecular Life Sciences. 77, 16, p. 3161-3176

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    The collagen receptor uPARAP/Endo180 regulates collectins through unique structural elements in its FNII domain

    Nørregaard, Kirstine Sandal, Krigslund, O., Behrendt, Niels, Engelholm, Lars Henning & Jürgensen, Henrik Jessen, 2020, In: Journal of Biological Chemistry. 295, 27, p. 9157-9170 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Tumor cell MT1-MMP is dispensable for osteosarcoma tumor growth, bone degradation and lung metastasis

    Ingvarsen, S. Z., Gårdsvoll, Henrik, van Putten, Sander Maarten, Nørregaard, Kirstine Sandal, Krigslund, O., Meilstrup, Josephine Amalie, Tran, C., Jürgensen, Henrik Jessen, Melander, M. C., Nielsen, Carsten Haagen, Kjær, Andreas, Bugge, T. H., Engelholm, Lars Henning & Behrendt, Niels, 2020, In: Scientific Reports. 10, 1, p. 1-16 19138.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. 2019
  12. Published

    Immune regulation by fibroblasts in tissue injury depends on uPARAP-mediated uptake of collectins

    Jürgensen, Henrik Jessen, Nørregaard, Kirstine Sandal, Sibree, M. M., Santoni Rugiu, Eric, Madsen, Daniel Hargbøl, Wassilew, K., Krustrup, D., Garred, Peter, Bugge, T. H., Engelholm, Lars Henning & Behrendt, Niels, 1 Jan 2019, In: Journal of Cell Biology. 218, 1, p. 333-349 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    CCL2/MCP-1 signaling drives extracellular matrix turnover by diverse macrophage subsets

    Jürgensen, Henrik Jessen, Silva, L. M., Krigslund, O., Van Putten, S., Madsen, D. H., Behrendt, Niels, Engelholm, Lars Henning & Bugge, T. H., 2019, In: Matrix Biology Plus. 1, p. 1-20 100003.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. 2017
  15. Published

    Tumor-Associated Macrophages Derived from Circulating Inflammatory Monocytes Degrade Collagen through Cellular Uptake

    Madsen, Daniel Hargbøl, Jürgensen, Henrik Jessen, Siersbæk, M. S., Kuczek, D. E., Grey Cloud, L., Liu, S., Behrendt, Niels, Grøntved, L., Weigert, R. & Bugge, T. H., 26 Dec 2017, In: Cell Reports. 21, 13, p. 3662-3671 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Matriptase zymogen supports epithelial development, homeostasis and regeneration

    Friis, S., Tadeo, D., Le-Gall, S. M., Jürgensen, Henrik Jessen, Sales, K. U., Camerer, E. & Bugge, T. H., 2017, In: B M C Biology. 15, 17 p., 46.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    The collagen receptor uPARAP/Endo180 as a novel target for antibody-drug conjugate mediated treatment of mesenchymal and leukemic cancers

    Nielsen, C. F., van Putten, S. M., Lund, I. K., Melander, M. C., Nørregaard, Kirstine Sandal, Jürgensen, Henrik Jessen, Reckzeh, K., Christensen, K. R., Ingvarsen, S. Z., Gårdsvoll, Henrik, Jensen, K. E., Hamerlik, P., Engelholm, Lars Henning & Behrendt, Niels, 2017, In: OncoTarget. 8, 27, p. 44605-44624 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. 2016
  19. Published

    Crystal structures of the ligand-binding region of uPARAP: effect of calcium ion binding

    Yuan, C., Jürgensen, Henrik Jessen, Engelholm, Lars Henning, Li, R., Liu, M., Jiang, L., Luo, Z., Behrendt, Niels & Huang, M., 1 Aug 2016, In: Biochemical Journal. 473, 15, p. 2359-68 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Targeting a novel bone degradation pathway in primary bone cancer by inactivation of the collagen receptor uPARAP/Endo180

    Engelholm, Lars Henning, Carlsen Melander, E. M., Hald, A., Persson, M., Madsen, D. H., Jürgensen, Henrik Jessen, Johansson, K., Nielsen, C., Nørregaard, Kirstine Sandal, Ingvarsen, S. Z., Kjær, Andreas, Trovik, C. S., Lærum, O. D., Bugge, T. H., Eide, J. & Behrendt, Niels, Jan 2016, In: Journal of Pathology. 238, 1, p. 120-33 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    A CCR2 macrophage endocytic pathway mediates extravascular fibrin clearance in vivo

    Motley, M. P., Madsen, Daniel Hargbøl, Jürgensen, Henrik Jessen, Spencer, D. E., Szabo, R., Holmbeck, Kenn, Flick, M. J., Lawrence, D. A., Castellino, F. J., Weigert, R. & Bugge, T. H., 2016, In: Blood. 127, 9, p. 1085-1096 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. 2015
  23. Published

    The collagen receptor uPARAP/Endo180 in tissue degradation and cancer (Review)

    Carlsen Melander, E. M., Jürgensen, Henrik Jessen, Madsen, Daniel Hargbøl, Engelholm, Lars Henning & Behrendt, Niels, Oct 2015, In: International Journal of Oncology. 47, 4, p. 1177-88 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. 2014
  25. Published

    Complex Determinants in Specific Members of the Mannose Receptor Family Govern Collagen Endocytosis

    Jürgensen, Henrik Jessen, Johansson, K., Madsen, D. H., Porse, A., Melander, M. C., Sørensen, K. R., Nielsen, C., Bugge, T. H., Behrendt, Niels & Engelholm, Lars Henning, 2014, In: The Journal of Biological Chemistry. 289, 11, p. 7935-7947 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. 2013
  27. Published

    M2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pathway

    Madsen, Daniel Hargbøl, Leonard, D., Masedunskas, A., Moyer, A., Jürgensen, Henrik Jessen, Peters, D. E., Amornphimoltham, P., Selvaraj, A., Yamada, S. S., Brenner, D. A., Burgdorf, S., Engelholm, Lars Henning, Behrendt, Niels, Holmbeck, K., Weigert, R. & Bugge, T. H., 16 Sep 2013, In: Journal of Cell Biology. 202, 6, p. 951-66 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Ficolin-1-PTX3 complex formation promotes clearance of altered self-cells and modulates IL-8 production

    Ma, Y. J., Doni, A., Romani, L., Jürgensen, Henrik Jessen, Behrendt, Niels, Mantovani, A. & Garred, Peter, 1 Aug 2013, In: Journal of immunology (Baltimore, Md. : 1950). 191, 3, p. 1324-33 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Differential actions of the endocytic collagen receptor uPARAP/Endo180 and the collagenase MMP-2 in bone homeostasis

    Madsen, Daniel Hargbøl, Jürgensen, Henrik Jessen, Ingvarsen, S., Melander, M. C., Albrechtsen, Reidar, Hald, A., Holmbeck, K., Bugge, T. H., Behrendt, Niels & Engelholm, Lars Henning, 2013, In: PloS one. 8, 8, p. e71261

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. 2011
  31. Published

    The non-phagocytic route of collagen uptake: a distinct degradation pathway

    Madsen, Daniel Hargbøl, Ingvarsen, S., Jürgensen, Henrik Jessen, Melander, M. C., Kjøller, L., Moyer, A., Honoré, C., Madsen, M. C., Garred, Peter, Burgdorf, S., Bugge, T. H., Behrendt, Niels & Engelholm, Lars Henning, 29 Jul 2011, In: The Journal of Biological Chemistry. 286, 30, p. 26996-7010 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    A novel functional role of collagen glycosylation: interaction with the endocytic collagen receptor uPARAP/ENDO 180

    Jürgensen, Henrik Jessen, Madsen, Daniel Hargbøl, Ingvarsen, S., Melander, M. C., Gårdsvoll, Henrik, Patthy, L., Engelholm, Lars Henning & Behrendt, Niels, 2011, In: Journal of Biological Chemistry. 286, 37, p. 32736-48 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. 2009
  34. Published

    The collagen receptor uPARAP/Endo180

    Engelholm, Lars Henning, Ingvarsen, S., Jürgensen, Henrik Jessen, Hillig, T., Madsen, Daniel Hargbøl, Nielsen, B. S. & Behrendt, Niels, 1 Jan 2009, In: Frontiers in Bioscience. 14, p. 2103-14 12 p.

    Research output: Contribution to journal › Review › Research › peer-review

ID: 98355375