Jesper Bøje Andersen
Professor
Andersen Group
Ole Maaløes Vej 5
2200 København N.
- 2024
- Published
Molecular portraits of patients with intrahepatic cholangiocarcinoma who diverge as rapid progressors or long survivors on chemotherapy
O'Rourke, C. J., Salati, M., Rae, C., Carpino, G., Leslie, H., Pea, A., Prete, M. G., Bonetti, L. R., Amato, F., Montal, R., Upstill-Goddard, R., Nixon, C., Sanchon-Sanchez, P., Kunderfranco, P., Sia, D., Gaudio, E., Overi, D., Cascinu, S., Hogdall, D., Pugh, S. & 15 others, , 2024, In: Gut. 73, p. 496-508Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Alternative promoters in CpG depleted regions are prevalently associated with epigenetic misregulation of liver cancer transcriptomes
Nepal, C. & Andersen, Jesper Bøje, 2023, In: Nature Communications. 14, 14 p., 2712.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combined Inhibition of Smoothened and the DNA Damage Checkpoint WEE1 Exerts Antitumor Activity in Cholangiocarcinoma
Anichini, G., Raggi, C., Pastore, M., Carrassa, L., Maresca, L., Crivaro, E., Lottini, T., Duwe, Lea, Andersen, Jesper Bøje, Tofani, L., Di Tommaso, L., Banales, J. M., Arcangeli, A., Marra, F. & Stecca, B., 2023, In: Molecular Cancer Therapeutics. 22, 3, p. 343-356 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Contribution of GD2 ganglioside to aggressivness of human cholangiocarcinoma
Mannini, A., Raggi, C., Correnti, M., Rovida, E., Aureli, M., Carsana, E. V., Piombanti, B., Pastore, M., Battula, V. L., Andersen, Jesper Bøje, Coulouarn, C. & Marra, F., 2023, In: Digestive and Liver Disease. 55, p. S43 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Criteria for preclinical models of cholangiocarcinoma: scientific and medical relevance
Calvisi, D. F., Boulter, L., Vaquero, J., Saborowski, A., Fabris, L., Rodrigues, P. M., Coulouarn, C., Castro, R. E., Segatto, O., Raggi, C., van der Laan, L. J. W., Carpino, G., Goeppert, B., Roessler, S., Kendall, T. J., Evert, M., Gonzalez-Sanchez, E., Valle, J. W., Vogel, A., Bridgewater, J. & 27 others, , 2023, In: Nature Reviews Gastroenterology and Hepatology. 20, p. 462-480Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fibroblast-Derived Lysyl Oxidase Increases Oxidative Phosphorylation and Stemness in Cholangiocarcinoma
Lewinska, M., Zhuravleva, E., Satriano, L., Martinez, M. B., Bhatt, D. K., Oliveira, D. V. N. P., Antoku, Y., Keggenhoff, F. L., Castven, D., Marquardt, J. U., Matter, M. S., Erler, J. T., Oliveira, R. C., Aldana, B. I., Al-Abdulla, R., Perugorria, M. J., Calvisi, D. F., Perez, L. A., Rodrigues, P. M., Labiano, I. & 2 others, , 2023, In: Gastroenterology. 166, 5, p. 886-901Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic and epigenetic analysis of hepatocellular adenomas with atypical morphological features
Haefliger, S., Hench, J., O'Rourke, Colm, Meyer-Schaller, N., Uzun, S., Saldarriaga, J., Weber, A., Mazzucchelli, L., Jermann, P., Frank, S., Andersen, Jesper Bøje, Terracciano, L., Sempoux, C. & Matter, M. S., 2023, In: Histopathology. 82, 5, p. 722–730 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Immunogenomics of cholangiocarcinoma
Gehl, Virag, O'Rourke, Colm & Andersen, Jesper Bøje, 2023, (E-pub ahead of print) In: Hepatology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Liquid biopsy-based protein biomarkers for risk prediction, early diagnosis and prognostication of cholangiocarcinoma
Lapitz, A., Azkargorta, M., Milkiewicz, P., Olaizola, P., Zhuravleva, E., Grimsrud, M. M., Schramm, C., Arbelaiz, A., O'Rourke, C. J., La Casta, A., Milkiewicz, M., Pastor, T., Vesterhus, M., Jimenez-Agüero, R., Dill, M. T., Lamarca, A., Valle, J. W., Macias, R. I. R., Izquierdo-Sanchez, L., Castaño, Y. P. & 15 others, , 2023, In: Journal of Hepatology. 79, 1, p. 93-108Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MicroRNA-27a-3p targets FoxO signalling to induce tumour-like phenotypes in bile duct cells
Duwe, Lea, Munoz-Garrido, P., Lewinska, Monika, Lafuente Barquero, Juan Francisco, Satriano, L., Høgdall, Dan Taksony Solyom, Taranta, A., Nielsen, B. S., Ghazal, A., Matter, M. S., Banales, J. M., Aldana, Blanca, Gao, Y., Marquardt, J. U., Roberts, L. R., Oliveira, R. C., Koshiol, J., O'Rourke, Colm & Andersen, Jesper Bøje, 2023, In: Journal of Hepatology. 78, 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preoperative immunological plasma markers TRAIL, CSF1 and TIE2 predict survival after resection for biliary tract cancer
Jansson, H., Cornillet, M., Sun, D., Filipovic, I., Sturesson, C., O’Rourke, C. J., Andersen, Jesper Bøje, Björkström, N. K. & Sparrelid, E., 2023, In: Frontiers in Oncology. 13, 15 p., 1169537.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Serum lipidome unravels a diagnostic potential in bile acid diarrhoea
Lewinska, M., Kårhus, M. L., Ellegaard, A. G., Romero-Gómez, M., Macias, R. I. R., Andersen, Jesper Bøje & Knop, Filip Krag, 2023, In: Gut. 72, 9, p. 1698-1708Research output: Contribution to journal › Journal article › Research › peer-review
- Published
miR-21-5p promotes NASH-related hepatocarcinogenesis
Rodrigues, P. M., Afonso, M. B., Simão, A. L., Islam, T., Gaspar, M. M., O'Rourke, Colm, Lewinska, Monika, Andersen, Jesper Bøje, Arretxe, E., Alonso, C., Santos-Laso, Á., Izquierdo-Sanchez, L., Jimenez-Agüero, R., Eizaguirre, E., Bujanda, L., Pareja, M. J., Prip-Buus, C., Banales, J. M., Rodrigues, C. M. P. & Castro, R. E., 2023, In: Liver International. 43, 10, p. 2256-2274 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Cholangiocarcinoma landscape in Europe: diagnostic, prognostic and therapeutic insights from the ENSCCA Registry
Izquierdo-Sanchez, L., Lamarca, A., La Casta, A., Buettner, S., Utpatel, K., Klümpen, H-J., Adeva, J., Vogel, A., Lleo, A., Fabris, L., Ponz-Sarvise, M., Brustia, R., Cardinale, V., Braconi, C., Vidili, G., Jamieson, N. B., Macias, R. I., Jonas, J. P., Marzioni, M., Hołówko, W. & 24 others, , 2022, In: Journal of Hepatology. 76, 5, p. 1109-1121Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cholangiocarcinoma progression depends on the uptake and metabolization of extracellular lipids
Ruiz de Gauna, M., Biancaniello, F., González-Romero, F., Rodrigues, P. M., Lapitz, A., Gómez-Santos, B., Olaizola, P., Di Matteo, S., Aurrekoetxea, I., Labiano, I., Nieva-Zuluaga, A., Benito-Vicente, A., Perugorria, M. J., Apodaka-Biguri, M., Paiva, N. A., Sáenz de Urturi, D., Buqué, X., Delgado, I., Martín, C., Azkargorta, M. & 8 others, , 2022, In: Hepatology. 76, 6, p. 1617-1633Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Driver mutations of intrahepatic cholangiocarcinoma shape clinically relevant genomic clusters with distinct molecular features and therapeutic vulnerabilities
Wang, X. Y., Zhu, W. W., Wang, Z., Huang, J. B., Wang, S. H., Bai, F. M., Li, T. E., Zhu, Y., Zhao, J., Yang, X., Lu, L., Zhang, J. B., Jia, H. L., Dong, Q. Z., Chen, J. H., Andersen, Jesper Bøje, Ye, D. & Qin, L. X., 2022, In: Theranostics. 27, 1, p. 260-276 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Involvement of Epigenomic Factors in Bile Duct Cancer
Rogalska-Taranta, Magdalena & Andersen, Jesper Bøje, 2022, In: Seminars in Liver Disease. 42, 2, p. 202-211 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipid alterations in chronic liver disease and liver cancer
Paul, Bichitra, Lewinska, Monika & Andersen, Jesper Bøje, 2022, In: JHEP Reports. 4, 6, 18 p., 100479.Research output: Contribution to journal › Review › Research › peer-review
- Published
Molecular therapeutic targets for cholangiocarcinoma: Present challenges and future possibilities
Høgdall, Dan Taksony Solyom, O'Rourke, Colm & Andersen, Jesper Bøje, 2022, Advances in Cancer Research. Academic Press, Vol. 156. p. 343-366 (Advances in Cancer Research).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Mucosal-associated invariant T-cell tumor infiltration predicts long-term survival in cholangiocarcinoma
Zimmer, C. L., Filipovic, I., Cornillet, M., O'Rourke, Colm, Berglin, L., Jansson, H., Sun, D., Strauss, O., Hertwig, L., Johansson, H., von Seth, E., Sparrelid, E., Dias, J., Glaumann, H., Melum, E., Ellis, E. C., Sandberg, J. K., Andersen, Jesper Bøje, Bergquist, A. & Björkström, N. K., 2022, In: Hepatology. 75, 5, p. 1154-1168Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutational signatures and processes in hepatobiliary cancers
Zhuravleva, Ekaterina, O'Rourke, Colm & Andersen, Jesper Bøje, 2022, In: Nature Reviews. Gastroenterology & Hepatology. 19, p. 367-382Research output: Contribution to journal › Review › Research › peer-review
- Published
Stromal yin-yang of myofibroblasts and endothelial cells in the progression of intrahepatic cholangiocarcinoma
Andersen, Jesper Bøje, 2022, In: Hepatology. 76, 5, p. 1233-1236Research output: Contribution to journal › Editorial › Research
- Published
Targeting NAE1-mediated protein hyper-NEDDylation halts cholangiocarcinogenesis and impacts on tumor-stroma crosstalk in experimental models
Olaizola, P., Lee-Law, P. Y., Fernandez-Barrena, M. G., Alvarez, L., Cadamuro, M., Azkargorta, M., O'Rourke, C. J., Caballero-Camino, F. J., Olaizola, I., Macias, R. I. R., Marin, J. J. G., Serrano-Maciá, M., Martinez-Chantar, M. L., Avila, M. A., Aspichueta, P., Calvisi, D. F., Evert, M., Fabris, L., Castro, R. E., Elortza, F. & 5 others, , 2022, In: Journal of Hepatology. 77, 1, p. 177-190Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The protease-inhibitor SerpinB3 as a critical modulator of the stem-like subset in human cholangiocarcinoma
Correnti, M., Cappon, A., Pastore, M., Piombanti, B., Lori, G., Oliveira, D. V. P. N., Munoz-Garrido, P., Lewinska, M., Andersen, J. B., Coulouarn, C., Sulpice, L., Peraldo Neia, C., Cavalloni, G., Quarta, S., Biasiolo, A., Fassan, M., Ramazzotti, M., Parri, M., Recalcati, S., di Tommaso, L. & 6 others, , 2022, In: Liver International. 42, 1, p. 233-248Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unraveling the actin cytoskeleton in the malignant transformation of cholangiocyte biology
Duwe, Lea, Fouassier, L., Lafuente Barquero, Juan Francisco & Andersen, Jesper Bøje, 2022, In: Translational Oncology. 26, 13 p., 101531.Research output: Contribution to journal › Review › Research › peer-review
- Published
Whole blood microRNAs capture systemic reprogramming and have diagnostic potential in patients with biliary tract cancer
Høgdall, Dan Taksony Solyom, O'Rourke, Colm, Larsen, F. O., Zarforoushan, S., Christensen, Troels Dreier, Ghazal, A., Boisen, M. K., Muñoz-Garrido, P., Johansen, Julia Sidenius & Andersen, Jesper Bøje, 2022, In: Journal of Hepatology. 77, p. 1047-1058 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
miR-579-3p Controls Hepatocellular Carcinoma Formation by Regulating the Phosphoinositide 3-Kinase–Protein Kinase B Pathway in Chronically Inflamed Liver
Quintavalle, C., Meyer-Schaller, N., Roessler, S., Calabrese, D., Marone, R., Riedl, T., Picco-Rey, S., Panagiotou, O. A., Uzun, S., Piscuoglio, S., Boldanova, T., Bian, C. B., Semela, D., Jochum, W., Cathomas, G., Mertz, K. D., Diebold, J., Mazzucchelli, L., Koelzer, V. H., Weber, A. & 7 others, , 2022, In: Hepatology Communications. 6, 6, p. 1467-1481Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Co-expression of YAP and TAZ associates with chromosomal instability in human cholangiocarcinoma
Tóth, M., Wehling, L., Thiess, L., Rose, F., Schmitt, J., Weiler, S. M. E., Sticht, C., De La Torre, C., Rausch, M., Albrecht, T., Grabe, N., Duwe, L., Andersen, J. B., Köhler, B. C., Springfeld, C., Mehrabi, A., Kulu, Y., Schirmacher, P., Roessler, S., Goeppert, B. & 1 others, , 2021, In: BMC Cancer. 21, 1, 14 p., 1079.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DNA Methylation in Ovarian Tumors - a Comparison Between Fresh Tissue and FFPE Samples
Oliveira, D. V. N. P., Hentze, J., O'Rourke, Colm, Andersen, Jesper Bøje, Høgdall, Claus Kim & Høgdall, Estrid Vilma Solyom, 2021, In: Reproductive Sciences. 28, 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
E2F1 and E2F2-mediated repression of CPT2 establishes a lipid-rich tumor-promoting environment
Gonzalez-Romero, F., Mestre, D., Aurrekoetxea, I., O'Rourke, C. J., Andersen, J. B., Woodhoo, A., Tamayo-Caro, M., Varela-Rey, M., Palomo-Irigoyen, M., Gomez-Santos, B., de Urturi, D. S., Nuñez-García, M., García-Rodríguez, J. L., Fernandez-Ares, L., Buque, X., Iglesias-Ara, A., Bernales, I., de Juan, V. G., Delgado, T. C., Goikoetxea-Usandizaga, N. & 15 others, , 2021, In: Cancer Research. 81, 11, p. 2874-2887 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Epigenetic modifications precede molecular alterations and drive human hepatocarcinogenesis
Czauderna, C., Poplawski, A., O'Rourke, Colm, Castven, D., Pérez-Aguilar, B., Becker, D., Heilmann-Heimbach, S., Odenthal, M., Amer, W., Schmiel, M., Drebber, U., Binder, H., Ridder, D. A., Schindeldecker, M., Straub, B. K., Galle, P. R., Andersen, Jesper Bøje, Thorgeirsson, S. S., Park, Y. N. & Marquardt, J. U., 2021, In: JCI insight. 6, 17, 19 p., e146196.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Extracellular Signal-Regulated Kinase 5 Regulates the Malignant Phenotype of Cholangiocarcinoma Cells
Gentilini, A., Lori, G., Caligiuri, A., Raggi, C., Di Maira, G., Pastore, M., Piombanti, B., Lottini, T., Arcangeli, A., Madiai, S., Navari, N., Banales, J. M., Di Matteo, S., Alvaro, D., Duwe, L., Andersen, J. B., Tubita, A., Tusa, I., Di Tommaso, L., Campani, C. & 2 others, , 2021, In: Hepatology. 74, 4, p. 2007-2020Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial oxidative metabolism contributes to a cancer stem cell phenotype in cholangiocarcinoma
Raggi, C., Taddei, M. L., Sacco, E., Navari, N., Correnti, M., Piombanti, B., Pastore, M., Campani, C., Pranzini, E., Iorio, J., Lori, G., Lottini, T., Peano, C., Cibella, J., Lewinska, M., Andersen, J. B., di Tommaso, L., Viganò, L., Di Maira, G., Madiai, S. & 5 others, , 2021, In: Journal of Hepatology. 74, 6, p. 1373-1385 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular targets in cholangiocarcinoma
O'Rourke, Colm, Munoz-Garrido, P. & Andersen, Jesper Bøje, 2021, In: Hepatology. 73, S1, p. 62-74Research output: Contribution to journal › Review › Research › peer-review
- Published
PIAS2-mediated blockade of IFN-β signaling: a basis for sporadic Parkinson disease dementia
Magalhaes, J., Tresse, E., Ejlerskov, P., Hu, E., Liu, Y., Marin, A., Montalant, A., Satriano, L., Rundsten, C. F., Carlsen, E. M. M., Rydbirk, R., Sharifi-Zarchi, A., Andersen, J. B., Aznar, S., Brudek, T., Khodosevich, K., Prinz, M., Perrier, J. F. M., Sharma, M., Gasser, T. & 1 others, , 2021, In: Molecular Psychiatry. 26, p. 6083–6099 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural aberrations are associated with poor survival in patients with clonal cytopenia of undetermined significance
Mikkelsen, Stine Ulrik, Safavi, S., Dimopoulos, K., O'Rourke, Colm, Andersen, M. K., Holm, M. S., Marcher, C. W., Andersen, Jesper Bøje, Hansen, Jakob Werner & Grønbæk, Kirsten, 2021, In: Haematologica. 106, 6Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
The altered serum lipidome and its diagnostic potential for Non-Alcoholic Fatty Liver (NAFL)-associated hepatocellular carcinoma: Diagnosis of NAFLD-HCC utilising serum lipidomics
Lewinska, M., Santos-Laso, A., Arretxe, E., Alonso, C., Zhuravleva, E., Jimenez-Agüero, R., Eizaguirre, E., Pareja, M. J., Romero-Gómez, M., Jimenez, M. A., Suppli, M. P., Knop, F. K., Oversoe, S. K., Villadsen, G. E., Decaens, T., Carrilho, F. J., de Oliveira, C. PMS., Sangro, B., Macias, R. I. R., Banales, J. M. & 1 others, , 2021, In: EBioMedicine. 73, 103661.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Ganglioside patterns in the human cholangiocarcinoma stem cell subset A
Mannini, A., Raggi, C., Correnti, M., Rovida, E., Piombanti, B., Pastore, M., Aureli, M., Carsana, E. V., Andersen, Jesper Bøje, Coulouarn, C. & Marra, F., 1 Feb 2020, In: Digestive and Liver Disease. 52, p. e11 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Mitochondrial oxidative metabolism contributes to maintain a cancer stem cell phenotype in cholangiocarcinoma
Raggi, C., Taddei, M. L., Sacco, E., Navari, N., Correnti, M., Piombanti, B., Pastore, M., Iorio, J., Lori, G., Peano, C., Cibella, J., Lewinska, Monika, Andersen, Jesper Bøje, Di Maira, G., Ramazzotti, M., Orlandi, I., Chiarugi, P. & Marra, F., 1 Feb 2020, In: Digestive and Liver Disease. 52, p. e47 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Identification of a Pan-Gamma-Secretase Inhibitor Response Signature for Notch-Driven Cholangiocarcinoma
O'Rourke, Colm, Matter, M. S., Nepal, C., Caetano-Oliveira, R., Ton, P. T., Factor, V. M. & Andersen, Jesper Bøje, Jan 2020, In: Hepatology. 71, 1, p. 196-213 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ancestrally Duplicated Conserved Noncoding Element Suggests Dual Regulatory Roles of HOTAIR in cis and trans
Nepal, C., Taranta, A., Hadzhiev, Y., Pundhir, Sachin, Mydel, P., Lenhard, B., Müller, F. & Andersen, Jesper Bøje, 2020, In: iScience. 23, 4, p. 1-27 UNSP 101008.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cholangiocarcinoma 2020: the next horizon in mechanisms and management
Banales, J. M., Marin, J. J. G., Lamarca, A., Rodrigues, P. M., Khan, S. A., Roberts, L. R., Cardinale, V., Carpino, G., Andersen, J. B., Braconi, C., Calvisi, D. F., Perugorria, M. J., Fabris, L., Boulter, L., Macias, R. I. R., Gaudio, E., Alvaro, D., Gradilone, S. A., Strazzabosco, M., Marzioni, M. & 14 others, , 2020, In: Nature Reviews. Gastroenterology & Hepatology. 17, 9, p. 557-588Research output: Contribution to journal › Review › Research › peer-review
- Published
Determination of primary microRNA processing in clinical samples by targeted pri-miR-sequencing
Conrad, T., Ntini, E., Lang, B., Cozzuto, L., Andersen, Jesper Bøje, Marquardt, J. U., Ponomarenko, J., Tartaglia, G. G. & Vang Orom, U. A., 2020, In: R N A. 26, 11, p. 1726-1730Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dual-initiation promoters with intertwined canonical and TCT/TOP transcription start sites diversify transcript processing
Nepal, C., Hadzhiev, Y., Balwierz, P., Tarifeño-Saldivia, E., Cardenas, R., Wragg, J. W., Suzuki, A. M., Carninci, P., Peers, B., Lenhard, B., Andersen, Jesper Bøje & Müller, F., 2020, In: Nature Communications. 11, 1, p. 1-16 168.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integrative molecular characterization of gallbladder cancer reveals microenvironment-associated subtypes
Nepal, C., Zhu, B., O'Rourke, C. J., Bhatt, D. K., Lee, D., Song, L., Wang, D., Van Dyke, A., Choo-Wosoba, H., Liu, Z., Hildesheim, A., Goldstein, A. M., Dean, M., LaFuente-Barquero, J., Lawrence, S., Mutreja, K., Olanich, M. E., Bermejo, J. L., Ferreccio, C., Roa, J. C. & 8 others, , 2020, In: Journal of Hepatology. 7, 5, p. 1132-1144Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intrahepatic cholangiocarcinoma: A single-cell resolution unraveling the complexity of the tumor microenvironment
Fabris, L., Andersen, Jesper Bøje & Fouassier, L., 2020, In: Journal of Hepatology. 73, 5, p. 1007-1009Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Patients with Cholangiocarcinoma Present Specific RNA Profiles in Serum and Urine Extracellular Vesicles Mirroring the Tumor Expression: Novel Liquid Biopsy Biomarkers for Disease Diagnosis
Lapitz, A., Arbelaiz, A., O'Rourke, C. J., Lavin, J. L., Casta, A. L., Ibarra, C., Jimeno, J. P., Santos-Laso, A., Izquierdo-Sanchez, L., Krawczyk, M., Perugorria, M. J., Jimenez-Aguero, R., Sanchez-Campos, A., Riaño, I., Gónzalez, E., Lammert, F., Marzioni, M., Macias, R. I. R., Marin, J. J. G., Karlsen, T. H. & 6 others, , 2020, In: Cells. 9, 3, p. 1-33Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Serum IL6 as a Prognostic Biomarker and IL6R as a Therapeutic Target in Biliary Tract Cancers
Høgdall, Dan Taksony Solyom, O'Rourke, Colm, Dehlendorff, C., Larsen, O. F., Jensen, L. H., Johansen, A. Z., Dang, H., Factor, V. M., Grunnet, M., Mau-Sørensen, M., Oliveira, D. V. N. P., Linnemann, D., Boisen, M. K., Wang, X. W., Johansen, Julia Sidenius & Andersen, Jesper Bøje, 2020, In: Clinical Cancer Research. 26, 21, 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TREM-2 defends the liver against hepatocellular carcinoma through multifactorial protective mechanisms
Esparza-Baquer, A., Labiano, I., Sharif, O., Agirre-Lizaso, A., Oakley, F., Rodrigues, P. M., Zhuravleva, E., O'Rourke, C. J., Hijona, E., Jimenez-Agüero, R., Riaño, I., Landa, A., La Casta, A., Zaki, M. Y. W., Munoz-Garrido, P., Azkargorta, M., Elortza, F., Vogel, A., Schabbauer, G., Aspichueta, P. & 6 others, , 2020, In: Gut. 70, 7Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Therapeutic Rationale to Target Highly Expressed Aurora kinase A Conferring Poor Prognosis in Cholangiocarcinoma
Ding, X., Huang, T., Peng, C., Ahn, K. S., Andersen, Jesper Bøje, Lewinska, Monika, Cao, Y., Xu, G., Chen, G., Kong, B., Friess, H., Shen, S., Roberts, L. R., Wang, L. & Zou, X., 2020, In: Journal of Cancer. 11, 8, p. 2241-2251 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
A morphogenetic EphB/EphrinB code controls hepatopancreatic duct formation
Thestrup, M. I., Caviglia, Sara, Cayuso, J., Heyne, R. L. S., Ahmad, R., Hofmeister, W., Satriano, L., Wilkinson, D. G., Andersen, Jesper Bøje & Ober, Elke, 19 Nov 2019, In: Nature Communications. 10, 1, 14 p., 5220.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Causes of hOCT1-dependent cholangiocarcinoma resistance to sorafenib and sensitization by tumor-selective gene therapy
Lozano, E., Macias, R. I. R., Monte, M. J., Asensio, M., Del Carmen, S., Sanchez-Vicente, L., Alonso-Peña, M., Al-Abdulla, R., Munoz-Garrido, P., Satriano, L., O'Rourke, Colm, Banales, J. M., Avila, M. A., Martinez-Chantar, M. L., Andersen, Jesper Bøje, Briz, O. & Marin, J. J. G., Oct 2019, In: Hepatology. 70, 4, p. 1246-1261 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acquisition of stem-like features in human cholangiocarcinoma is associated with an oxidative metabolism
Raggi, C., Navari, N., Taddei, M. L., Sacco, E., Correnti, M., Piombanti, B., Andersen, Jesper Bøje, Ramazzotti, M., Orlandi, I., Chiarugi, P. & Marra, F., 2019, In: Digestive and Liver Disease. 51, e34.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Application of patient-derived liver cancer cells for phenotypic characterization and therapeutic target identification
Castven, D., Becker, D., Czauderna, C., Wilhelm, D., Andersen, J. B., Strand, S., Hartmann, M., Heilmann-Heimbach, S., Roth, W., Hartmann, N., Straub, B. K., Mahn, F. L., Franck, S., Pereira, S., Haupts, A., Vogel, A., Wörns, M. A., Weinmann, A., Heinrich, S., Lang, H. & 3 others, , 2019, In: International Journal of Cancer. 144, 11, p. 2782-2794 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cholangiocarcinoma: State-of-the-art knowledge and challenges
Banales, J. M., Cardinale, V., Macias, R. I. R., Andersen, Jesper Bøje, Braconi, C., Carpino, G., Alvaro, D. & Calvisi, D. F., 2019, In: Liver International. 39, S1, p. 5-6 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Epigenetic events involved in organic cation transporter 1-dependent impaired response of hepatocellular carcinoma to sorafenib
Al-Abdulla, R., Lozano, E., Macias, R. I. R., Monte, M. J., Briz, O., O'Rourke, Colm, Serrano, M. A., Banales, J. M., Avila, M. A., Martinez-Chantar, M. L., Geier, A., Andersen, Jesper Bøje & Marin, J. J. G., 2019, In: British Journal of Pharmacology. 176, 6, p. 787-800Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Epigenome Remodeling in Cholangiocarcinoma
O'Rourke, Colm, Lafuente Barquero, Juan Francisco & Andersen, Jesper Bøje, 2019, In: Trends in Cancer. 5, 6, p. 335-350 16 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Ganglioside composition correlates with the malignant phenotype of cholangiocarcinoma cells and modulates cell adhesion
Mannini, A., Raggi, C., Correnti, M., Rovida, E., Andersen, Jesper Bøje, Coulouarn, C. & Marra, F., 2019, In: Digestive and Liver Disease. 51, p. e7Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Identification of a pan-gamma-secretase inhibitor response signature for notch-driven cholangiocarcinoma
O'Rourke, Colm, Matter, M., Nepal, C., Ton, P., Factor, V. & Andersen, Jesper Bøje, 2019, In: Journal of Hepatology. 70, 1, p. e28Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Metabolic rearrangements in primary liver cancers: cause and consequences
Satriano, L., Lewinska, Monika, Rodrigues, P. M., Banales, J. M. & Andersen, Jesper Bøje, 2019, In: Nature Reviews. Gastroenterology & Hepatology. 16, 12, p. 748-766 17 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Molecular Perturbations in Cholangiocarcinoma: Is it Time for Precision Medicine?
Braconi, C., Roessler, S., Kruk, B., Lammert, F., Krawczyk, M. & Andersen, Jesper Bøje, 2019, In: Liver International. 39, Suppl. 1, p. 32-42 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
THU-491-The role of alanine glyoxylate aminotransferase in hepatocellular carcinoma
Satriano, L., Lewinska, Monika, Rourke, C. O., Oliveira, D. V., Bhatt, D. K., Taranta, A., Herr, M., Straub, B., Conner, D. E. A., Budhu, D. A., Pomyen, Y., Ma, Tao, Gerhart-Hines, Zach, Stjernegaard, D. C. S., Matter, M., Crocoll, D. C., Wang, X. W., Marquardt, J. & Andersen, Jesper Bøje, 2019, p. e377.Research output: Contribution to conference › Poster › Research
- Published
The protein kinase CK2 contributes to the malignant phenotype of cholangiocarcinoma cells
Di Maira, G., Gentilini, A., Pastore, M., Caligiuri, A., Piombanti, B., Raggi, C., Rovida, E., Lewinska, Monika, Andersen, Jesper Bøje, Borgo, C., Salvi, M., Ottaviani, D., Ruzzene, M. & Marra, F., 2019, In: Oncogenesis. 8, 11, p. 61-72 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Therapeutic Potential of Pharmacoepigenetics in Cholangiocarcinoma
O'Rourke, Colm, Satriano, L., Oliveira, D. V. N. P., Munoz-Garrido, P. & Andersen, Jesper Bøje, 2019, Pharmacoepigenetics. Academic Press, p. 551-562 12 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- 2018
- Published
Genomic Perturbations Reveal Distinct Regulatory Networks in Intrahepatic Cholangiocarcinoma
Nepal, C., O'Rourke, Colm, Oliveira, D. V., Taranta, A., Shema, S., Gautam, P., Calderaro, J., Barbour, A., Raggi, C., Wennerberg, Krister, Wang, X. W., Lautem, A., Roberts, L. R. & Andersen, Jesper Bøje, Sep 2018, In: Hepatology. 68, 3, p. 949-963 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential effects of FXR or TGR5 activation in cholangiocarcinoma progression
Erice, O., Labiano, I., Arbelaiz, A., Santos-Laso, A., Munoz-Garrido, P., Jimenez-Agüero, R., Olaizola, P., Caro-Maldonado, A., Martín-Martín, N., Carracedo, A., Lozano, E., Marin, J. J., O'Rourke, C. J., Andersen, J. B., Llop, J., Gómez-Vallejo, V., Padro, D., Martin, A., Marzioni, M., Adorini, L. & 4 others, , Apr 2018, In: B B A - Reviews on Cancer. 1864, 4, Part B, p. 1335-1344Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Desmoplastic Tumor Microenvironment and Immunotherapy in Cholangiocarcinoma
Høgdall, Dan Taksony Solyom, Lewinska, Monika & Andersen, Jesper Bøje, Mar 2018, In: Trends in Cancer. 4, 3, p. 239-255 17 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
MIR21 drives resistance to Heat Shock Protein 90 inhibition in cholangiocarcinoma
Lampis, A., Carotenuto, P., Vlachogiannis, G., Cascione, L., Hedayat, S., Burke, R., Clarke, P., Bosma, E., Simbolo, M., Scarpa, A., Yu, S., Cole, R., Smyth, E., Mateos, J. F., Begum, R., Hezelova, B., Eltahir, Z., Wotherspoon, A., Fotiadis, N., Bali, M. A. & 14 others, , Mar 2018, In: Gastroenterology. 154, 4, p. 1066-1079Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reply to editorial letter
Koshiol, J., Andersen, Jesper Bøje & Ferreccio, C., Jan 2018, In: Gastroenterology. 154, 1, p. 260-261Research output: Contribution to journal › Comment/debate › Communication
- Published
Transcriptomic and histopathological analysis of cholangiolocellular differentiation trait in intrahepatic cholangiocarcinoma
Rhee, H., Ko, J. E., Chung, T., Jee, B. A., Kwon, S. M., Nahm, J. H., Seok, J. Y., Yoo, J. E., Choi, J., Thorgeirsson, S. S., Andersen, Jesper Bøje, Lee, H. S., Woo, H. G. & Park, Y. N., Jan 2018, In: Liver International. 38, 1, p. 113-124 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily
Cancer Genome Atlas Research Network, C. G. A. R. N., 2018, In: Cell Systems. 7, 4, p. 422-437.e1-e7 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Epigenome dysregulation in cholangiocarcinoma
O'Rourke, Colm, Munoz-Garrido, P., Aguayo, E. L. & Andersen, Jesper Bøje, 2018, In: BBA Molecular Basis of Disease. 1864, 4, Part B, p. 1423-1434 12 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
RNAi screening of subtracted transcriptomes reveals tumor suppression by taurine-activated GABAA receptors involved in volume regulation
Wielders, C. L. C., van Nierop, P., Vormer, T. L., Foijer, F., Verheij, J., Lodder, J. C., Andersen, Jesper Bøje, Mansvelder, H. D. & Te Riele, H., 2018, In: PLOS ONE. 13, 5, p. 1-26 26 p., e0196979.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single cell profiling reveals window for immunotherapy in liver cancers
Andersen, Jesper Bøje, 2018, In: Hepatobiliary surgery and nutrition. 7, 1, p. 48-51 4 p.Research output: Contribution to journal › Letter › Research › peer-review
- 2017
- Published
Dysregulation of Iron Metabolism in Cholangiocarcinoma Stem-like Cells
Raggi, C., Gammella, E., Correnti, M., Buratti, P., Forti, E., Andersen, Jesper Bøje, Alpini, G., Glaser, S., Alvaro, D., Invernizzi, P., Cairo, G. & Recalcati, S., 1 Dec 2017, In: Scientific Reports. 7, 1, 12 p., 17667.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phosphoprotein enriched in diabetes (PED/PEA15) promotes migration in hepatocellular carcinoma and confers resistance to sorafenib
Quintavalle, C., Hindupur, S. K., Quagliata, L., Pallante, P., Nigro, C., Condorelli, G., Andersen, Jesper Bøje, Tagscherer, K. E., Roth, W., Beguinot, F., Heim, M. H., Ng, C. K. Y., Piscuoglio, S. & Matter, M. S., 26 Oct 2017, In: Cell Death & Disease. 8, 10, 9 p., e3138.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High mobility group A1 enhances tumorigenicity of human cholangiocarcinoma and confers resistance to therapy
Quintavalle, C., Burmeister, K., Piscuoglio, S., Quagliata, L., Karamitopoulou, E., Sepe, R., Fusco, A., Terracciano, L. M., Andersen, Jesper Bøje, Pallante, P. & Matter, M. S., Sep 2017, In: Molecular Carcinogenesis. 56, 9, p. 2146–2157Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of Aflatoxin and Gallbladder Cancer
Koshiol, J., Gao, Y., Dean, M., Egner, P., Nepal, C., Jones, K., Wang, B., Rashid, A., Luo, W., Van Dyke, A., Ferreccio, C., Malasky, M., Shen, M., Zhu, B., Andersen, Jesper Bøje, Hildesheim, A., Hsing, A. W. & Groopman, J., Aug 2017, In: Gastroenterology. 153, 2, p. 488-494. e1Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Common Molecular Subtypes Among Asian Hepatocellular Carcinoma and Cholangiocarcinoma
Chaisaingmongkol, J., Budhu, A., Dang, H., Rabibhadana, S., Pupacdi, B., Kwon, S. M., Forgues, M., Pomyen, Y., Bhudhisawasdi, V., Lertprasertsuke, N., Chotirosniramit, A., Pairojkul, C., Auewarakul, C. U., Sricharunrat, T., Phornphutkul, K., Sangrajrang, S., Cam, M., He, P., Hewitt, S. M., Ylaya, K. & 17 others, , 10 Jul 2017, In: Cancer Cell. 32, 1, p. 57-70.e3Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles - correction
Farshidfar, F., Zheng, S., Gingras, M-C., Newton, Y., Shih, J., Robertson, A. G., Hinoue, T., Hoadley, K. A., Gibb, E. A., Roszik, J., Covington, K. R., Wu, C-C., Shinbrot, E., Stransky, N., Hegde, A., Yang, J. D., Reznik, E., Sadeghi, S., Pedamallu, C. S., Ojesina, A. I. & 24 others, , 27 Jun 2017, In: Cell Reports. 19, 13, p. 2878-2880 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Adverse genomic alterations and stemness features are induced by field cancerization in the microenvironment of hepatocellular carcinomas
Castven, D., Fischer, M., Becker, D., Heinrich, S., Andersen, Jesper Bøje, Strand, D., Sprinzl, M. F., Strand, S., Czauderna, C., Heilmann-Heimbach, S., Roessler, S., Weinmann, A., Wörns, M. A., Thorgeirsson, S. S., Galle, P. R., Matter, M. S., Lang, H. & Marquardt, J. U., 15 Mar 2017, In: OncoTarget. 8, 30, p. 48688-48700Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles
Farshidfar, F., Zheng, S., Gingras, M-C., Newton, Y., Shih, J., Robertson, A. G., Hinoue, T., Hoadley, K. A., Gibb, E. A., Roszik, J., Covington, K. R., Wu, C-C., Shinbrot, E., Stransky, N., Hegde, A., Yang, J. D., Reznik, E., Sadeghi, S., Pedamallu, C. S., Ojesina, A. I. & 24 others, , 14 Mar 2017, In: Cell Reports. 18, 11, p. 2780-2794 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SOX17 Regulates Cholangiocyte Differentiation and Acts as a Tumor Suppressor in Cholangiocarcinoma
Merino-Azpitarte, M., Lozano, E., Perugorria, M. J., Esparza-Baquer, A., Erice, O., Santos-Laso, A., O'Rourke, C., Andersen, J. B., Jiménez-Agüero, R., Lacasta, A., D'Amato, M., Briz, O., Jalan-Sakrikar, N., Huebert, R. C., Thelen, K. M., Gradilone, S. A., Aransay, A. M., Lavín, J. L., Fernández-Barrena, M. G., Matheu, A. & 5 others, , 22 Feb 2017, In: Journal of Hepatology. 67, 1, p. 72-83 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular profiling of intrahepatic cholangiocarcinoma: the search for new therapeutic targets
Oliveira, D. V. N. P., Zhang, S., Chen, X., Calvisi, D. F. & Andersen, Jesper Bøje, 4 Feb 2017, In: Expert Review of Gastroenterology & Hepatology. 11, 4, p. 349-356 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Cholangiocarcinoma stem-like subset shapes tumor-initiating niche by educating associated macrophages
Raggi, C., Correnti, M., Sica, A., Andersen, Jesper Bøje, Cardinale, V., Alvaro, D., Chiorino, G., Forti, E., Glaser, S., Alpini, G., Destro, A., Sozio, F., Di Tommaso, L., Roncalli, M., Banales, J. M., Coulouarn, C., Bujanda, L., Torzilli, G. & Invernizzi, P., Jan 2017, In: Journal of Hepatology. 66, 1, p. 102–115Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer
Vallejo, A., Perurena, N., Guruceaga, E., Mazur, P. K., Martinez-Canarias, S., Zandueta, C., Valencia, K., Arricibita, A., Gwinn, D., Sayles, L. C., Chuang, C-H., Guembe, L., Bailey, P., Chang, D. K., Biankin, A., Ponz-Sarvise, M., Andersen, J. B., Khatri, P., Bozec, A., Sweet-Cordero, E. A. & 3 others, , 2017, In: Nature Communications. 8, 14 p., 14294.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Chapter 9A - Advances in the molecular characterization of liver tumors
Matter, M. S. & Andersen, Jesper Bøje, 2 Dec 2016, Blumgart's Surgery of the Liver, Biliary Tract and Pancreas: Sixth Edition. Elsevier Science Inc., Vol. 1-2. p. 133-138.e2Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education › peer-review
- Published
Advances in cholangiocarcinoma research: report from the third Cholangiocarcinoma Foundation Annual Conference
Abou-Alfa, G. K., Andersen, J. B., Chapman, W., Choti, M., Forbes, S. J., Gores, G. J., Hong, T. S., Harding, J. J., Vander Heiden, M. G., Javle, M., Kelley, R. K., Kwong, L. N., Lowery, M., Merrell, A., Miyabe, K., Rhim, A., Saha, S., Sia, D., Tanasanvimon, S., Venook, A. & 7 others, , Dec 2016, In: Journal of Gastrointestinal Oncology. 7, 6, p. 819-827 9 p.Research output: Contribution to journal › Conference article › Research › peer-review
- Published
Genetic Optimization of Liver Cancer Therapy: A Patient-derived Primary Cancer Cell-based Model
Munoz-Garrido, P. & Andersen, Jesper Bøje, 23 Nov 2016, In: Gastroenterology. 152, 1Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Correction:p53-Dependent Nestin Regulation Links Tumor Suppression to Cellular Plasticity in Liver Cancer
Tschaharganeh, D. F., Xue, W., Calvisi, D. F., Evert, M., Michurina, T. V., Dow, L. E., Banito, A., Katz, S. F., Kastenhuber, E. R., Weissmueller, S., Huang, C., Lechel, A., Andersen, Jesper Bøje, Capper, D., Zender, L., Longerich, T., Enikolopov, G. & Lowe, S. W., 2 Jun 2016, In: Cell. 165, 6, p. 1546-1547 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Oncogenic driver genes and the inflammatory microenvironment dictate liver tumor phenotype
Matter, M. S., Marquardt, J. U., Andersen, Jesper Bøje, Quintavalle, C., Korokhov, N., Stauffer, J. K., Kaji, K., Decaens, T., Quagliata, L., Elloumi, F., Hoang, T., Molinolo, A., Conner, E. A., Weber, A., Heikenwalder, M., Factor, V. M. & Thorgeirsson, S. S., Jun 2016, In: Hepatology. 63, 6, p. 1888-1899 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA)
Banales, J. M., Cardinale, V., Carpino, G., Marzioni, M., Andersen, J. B., Invernizzi, P., Lind, G. E., Folseraas, T., Forbes, S. J., Fouassier, L., Geier, A., Calvisi, D. F., Mertens, J. C., Trauner, M., Benedetti, A., Maroni, L., Vaquero, J., Macias, R. I. R., Raggi, C., Perugorria, M. J. & 4 others, , May 2016, In: Nature Reviews. Gastroenterology & Hepatology. 13, 5, p. 261-80 20 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Expert consensus document: Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA)
Banales, J. M., Cardinale, V., Carpino, G., Marzioni, M., Andersen, J. B., Invernizzi, P., Lind, G. E., Folseraas, T., Forbes, S. J., Fouassier, L., Geier, A., Calvisi, D. F., Mertens, J. C., Trauner, M., Benedetti, A., Maroni, L., Vaquero, J., Macias, R. I. R., Raggi, C., Perugorria, M. J. & 4 others, , May 2016, In: Nature Reviews. Gastroenterology & Hepatology. 13, 5, p. 261-280 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heterogeneity Among Liver Cancer—A Hurdle to Optimizing Therapy
Birkbak, N. J. & Andersen, Jesper Bøje, Apr 2016, In: Gastroenterology. 150, 4, p. 818–821 4 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
DNMT1 is a Required Genomic Regulator for Murine Liver Histogenesis and Regeneration
Kaji, K., Factor, V. M., Andersen, Jesper Bøje, Durkin, M. E., Tomokuni, A., Marquardt, J. U., Matter, M. S., Hoang, T., Conner, E. A. & Thorgeirsson, S. S., 21 Mar 2016, In: Hepatology. 64, 2, p. 582–598 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
A Gene Expression Signature Associated With Overall Survival in Patients With Hepatocellular Carcinoma Suggests a New Treatment Strategy
Gillet, J., Andersen, Jesper Bøje, Madigan, J. P., Varma, S., Bagni, R. K., Powell, K., Burgan, W. E., Wu, C., Calcagno, A. M., Ambudkar, S. V., Thorgeirsson, S. S. & Gottesman, M., 2016, In: Molecular Pharmacology. 89, 2, p. 263-272 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular Pathogenesis and Current Therapy in Intrahepatic Cholangiocarcinoma
Høgdall, Dan Taksony Solyom, O'Rourke, Colm, Taranta, A., NP Oliveira, D. & Andersen, Jesper Bøje, 2016, In: Digestive Diseases. 34, 4, p. 440-51 12 p.Research output: Contribution to journal › Review › Research › peer-review
- 2015
- Published
Transcriptional, post-transcriptional and chromatin-associated regulation of pri-miRNAs, pre-miRNAs and moRNAs
Nepal, C., Coolen, M., Hadzhiev, Y., Cussigh, D., Mydel, P., Steen, V. M., Carninci, P., Andersen, Jesper Bøje, Bally-Cuif, L., Müller, F. & Lenhard, B., 15 Dec 2015, In: Nucleic Acids Research. 44, 11, p. 3070-3081 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Liver cancer oncogenomics: opportunities and dilemmas for clinical applications
Marquardt, J. U. & Andersen, Jesper Bøje, 11 Aug 2015, In: Hepatic Oncology. 2, 1, p. 79-93 15 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Curcumin effectively inhibits oncogenic NF-kB signaling and restrains stemness features in liver cancer
Marquardt, J. U., Gomez-Quiroz, L., Arreguin Camacho, L. O., Pinna, F., Lee, Y., Kitade, M., Domínguez, M. P., Castven, D., Breuhahn, K., Conner, E. A., Galle, P. R., Andersen, Jesper Bøje, Factor, V. M. & Thorgeirsson, S. S., 30 Apr 2015, In: Journal of Hepatology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fibrolamellar Hepatocellular Carcinoma: A Rare But Distinct Type of Liver Cancer
Andersen, Jesper Bøje, 24 Feb 2015, In: Gastroenterology.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Functional and genetic deconstruction of the cellular origin in liver cancer
Marquardt, J. U., Andersen, Jesper Bøje & Thorgeirsson, S. S., 2015, In: Nature Reviews. Cancer. 15, 11, p. 653-67 15 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Stimulating translational research: several European life science institutions put their heads together
Bentires-Alj, M., Rajan, A., van Harten, W., van Luenen, H. G. A. M., Kubicek, S., Andersen, Jesper Bøje, Saarela, J., Cook, S. J., Van Minnebruggen, G., Roman-Roman, S., Maurer, C., Erler, Janine & Bertero, M. G., 2015, In: Trends in Molecular Medicine. 21, 9, p. 525-527 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Impact of Microenvironment and Stem-Like Plasticity in Cholangiocarcinoma: Molecular Networks and Biological Concepts
Raggi, C., Invernizzi, P. & Andersen, Jesper Bøje, 11 Sep 2014, In: Journal of Hepatology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MYC activates stem-like cell potential in hepatocarcinoma by a p53-dependent mechanism
Akita, H., Marquardt, J. U., Durkin, M. E., Kitade, M., Seo, D., Conner, E. A., Andersen, Jesper Bøje, Factor, V. M. & Thorgeirsson, S. S., 4 Sep 2014, In: Cancer Research.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular pathogenesis of intrahepatic cholangiocarcinoma
Andersen, Jesper Bøje, 1 Sep 2014, In: Journal of Hepato - Biliary - Pancreatic Sciences.Research output: Contribution to journal › Review › Research › peer-review
- Published
p53-Dependent Nestin Regulation Links Tumor Suppression to Cellular Plasticity in Liver Cancer
Tschaharganeh, D. F., Xue, W., Calvisi, D. F., Evert, M., Michurina, T. V., Dow, L. E., Banito, A., Katz, S. F., Kastenhuber, E. R., Weissmueller, S., Huang, C., Lechel, A., Andersen, Jesper Bøje, Capper, D., Zender, L., Longerich, T., Enikolopov, G. & Lowe, S. W., 31 Jul 2014, In: Cell. 158, 3, p. 579-92 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
Antitumor effects in hepatocarcinoma of isoform-selective inhibition of HDAC2
Lee, Y., Seo, D., Choi, K., Andersen, Jesper Bøje, Won, M., Kitade, M., Gomez-Quiroz, L. E., Judge, A. D., Marquardt, J. U., Raggi, C., Conner, E. A., MacLachlan, I., Factor, V. M. & Thorgeirsson, S., 23 Jun 2014, In: Cancer Research. 74, 17, p. 4752-4761 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Sequential transcriptome analysis of human liver cancer indicates late stage acquisition of malignant traits
Marquardt, J. U., Seo, D., Andersen, Jesper Bøje, Gillen, M. C., Kim, M. S., Conner, E. A., Galle, P. R., Factor, V. M., Park, Y. N. & Thorgeirsson, S. S., Feb 2014, In: Journal of Hepatology. 60, 2, p. 346-53 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Epigenetic reprogramming modulates malignant properties of human liver cancer
Raggi, C., Factor, V. M., Seo, D., Holczbauer, A., Gillen, M. C., Marquardt, J. U., Andersen, Jesper Bøje, Durkin, M. & Thorgeirsson, S. S., 21 Jan 2014, In: Hepatology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A perspective on molecular therapy in cholangiocarcinoma: present status and future directions
Andersen, Jesper Bøje & Thorgeirsson, S. S., 2014, In: Hepatic Oncology. 1, 1, p. 143-157 15 p.Research output: Contribution to journal › Review › Research › peer-review
Long noncoding RNA HOTTIP/HOXA13 expression is associated with disease progression and predicts outcome in hepatocellular carcinoma patients
Quagliata, L., Matter, M. S., Piscuoglio, S., Arabi, L., Ruiz, C., Procino, A., Kovac, M., Moretti, F., Makowska, Z., Boldanova, T., Andersen, Jesper Bøje, Hämmerle, M., Tornillo, L., Heim, M. H., Diederichs, S., Cillo, C. & Terracciano, L. M., 2014, In: Hepatology. 59, 3, p. 911-923Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
Targeting the mTOR pathway in hepatocellular carcinoma: Current state and future trends
Matter, M. S., Decaens, T., Andersen, Jesper Bøje & Thorgeirsson, S. S., 3 Dec 2013, In: Journal of Hepatology.Research output: Contribution to journal › Review › Research › peer-review
Specific fate decisions in adult hepatic progenitor cells driven by MET and EGFR signaling
Kitade, M., Factor, V. M., Andersen, Jesper Bøje, Tomokuni, A., Kaji, K., Akita, H., Holczbauer, A., Seo, D., Marquardt, J. U., Conner, E. A., Lee, S., Lee, Y. & Thorgeirsson, S. S., 1 Aug 2013, In: Genes & Development. 27, 15, p. 1706-17 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Modeling pathogenesis of primary liver cancer in lineage-specific mouse cell types
Holczbauer, A., Factor, V. M., Andersen, Jesper Bøje, Marquardt, J. U., Kleiner, D. E., Raggi, C., Kitade, M., Seo, D., Akita, H., Durkin, M. E. & Thorgeirsson, S. S., Jul 2013, In: Gastroenterology. 145, 1, p. 221-31 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas
Wang, P., Dong, Q., Zhang, C., Kuan, P-F., Liu, Y., Jeck, W. R., Andersen, J. B., Jiang, W., Savich, G. L., Tan, T-X., Auman, J. T., Hoskins, J. M., Misher, A. D., Moser, C. D., Yourstone, S. M., Kim, J. W., Cibulskis, K., Getz, G., Hunt, H. V., Thorgeirsson, S. S. & 6 others, , 20 Jun 2013, In: Oncogene. 32, 25, p. 3091-100 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Genomic decoding of intrahepatic cholangiocarcinoma reveals therapeutic opportunities
Andersen, Jesper Bøje & Thorgeirsson, S. S., Apr 2013, In: Gastroenterology. 144, 4, p. 687-90 4 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Molecular constituents of the extracellular matrix in rat liver mounting a hepatic progenitor cell response for tissue repair
Vestentoft, P. S., Jelnes, P., Andersen, Jesper Bøje, Tran, T. A. T., Jørgensen, T., Rasmussen, M., Lange, Jette Bornholdt, Grøvdal, L. M., Jensen, C. H., Vogel, Lotte, Thorgeirsson, S. S. & Bisgaard, Hanne Cathrine, 2013, In: Fibrogenesis & Tissue Repair. 6, 1, 15 p., 21.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
Transcriptomic profiling reveals hepatic stem-like gene signatures and interplay of miR-200c and epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma
Oishi, N., Kumar, M. R., Roessler, S., Ji, J., Forgues, M., Budhu, A., Zhao, X., Andersen, Jesper Bøje, Ye, Q., Jia, H., Qin, L., Yamashita, T., Woo, H. G., Kim, Y. J., Kaneko, S., Tang, Z., Thorgeirsson, S. S. & Wang, X. W., Nov 2012, In: Hepatology. 56, 5, p. 1792-803 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Next-Generation Sequencing: Application in Liver Cancer-Past, Present and Future?
Marquardt, J. U. & Andersen, Jesper Bøje, 31 Aug 2012, In: Biology. 1, 2, p. 383-394 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
mTOR inhibitors synergize on regression, reversal of gene expression, and autophagy in hepatocellular carcinoma
Thomas, H. E., Mercer, C. A., Carnevalli, L. S., Park, J., Andersen, Jesper Bøje, Conner, E. A., Tanaka, K., Matsutani, T., Iwanami, A., Aronow, B. J., Manway, L., Maira, S. M., Thorgeirsson, S. S., Mischel, P. S., Thomas, G. & Kozma, S. C., 20 Jun 2012, In: Science Translational Medicine. 4, 139, p. 139ra84Research output: Contribution to journal › Journal article › Research › peer-review
Genetic profiling of intrahepatic cholangiocarcinoma
Andersen, Jesper Bøje & Thorgeirsson, S. S., May 2012, In: Current Opinion in Gastroenterology. 28, 3, p. 266-72 7 p.Research output: Contribution to journal › Review › Research › peer-review
Genomic and genetic characterization of cholangiocarcinoma identifies therapeutic targets for tyrosine kinase inhibitors
Andersen, Jesper Bøje, Spee, B., Blechacz, B. R., Avital, I., Komuta, M., Barbour, A., Conner, E. A., Gillen, M. C., Roskams, T., Roberts, L. R., Factor, V. M. & Thorgeirsson, S. S., Apr 2012, In: Gastroenterology. 142, 4, p. 1021-1031.e15Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
Molecular targeting of CSN5 in human hepatocellular carcinoma: a mechanism of therapeutic response
Lee, Y., Judge, A. D., Seo, D., Kitade, M., Gómez-Quiroz, L. E., Ishikawa, T., Andersen, Jesper Bøje, Kim, B., Marquardt, J. U., Raggi, C., Avital, I., Conner, E. A., MacLachlan, I., Factor, V. M. & Thorgeirsson, S. S., 6 Oct 2011, In: Oncogene. 30, 40, p. 4175-84 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway
Viatour, P., Ehmer, U., Saddic, L. A., Dorrell, C., Andersen, Jesper Bøje, Lin, C., Zmoos, A., Mazur, P. K., Schaffer, B. E., Ostermeier, A., Vogel, H., Sylvester, K. G., Thorgeirsson, S. S., Grompe, M. & Sage, J., 26 Sep 2011, In: The Journal of Experimental Medicine. 208, 10, p. 1963-76 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
Human hepatic cancer stem cells are characterized by common stemness traits and diverse oncogenic pathways
Marquardt, J. U., Raggi, C., Andersen, Jesper Bøje, Seo, D., Avital, I., Geller, D., Lee, Y., Kitade, M., Holczbauer, A., Gillen, M. C., Conner, E. A., Factor, V. M. & Thorgeirsson, S. S., 2 Sep 2011, In: Hepatology. 54, 3, p. 1031-42 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Coactivation of AKT and β-catenin in mice rapidly induces formation of lipogenic liver tumors
Stauffer, J. K., Scarzello, A. J., Andersen, Jesper Bøje, De Kluyver, R. L., Back, T. C., Weiss, J. M., Thorgeirsson, S. S. & Wiltrout, R. H., 1 Apr 2011, In: Cancer Research. 71, 7, p. 2718-27 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
Definition of ubiquitination modulator COP1 as a novel therapeutic target in human hepatocellular carcinoma
Lee, Y., Andersen, Jesper Bøje, Song, H., Judge, A. D., Seo, D., Ishikawa, T., Marquardt, J. U., Kitade, M., Durkin, M. E., Raggi, C., Woo, H. G., Conner, E. A., Avital, I., Maclachlan, I., Factor, V. M. & Thorgeirsson, S. S., 1 Nov 2010, In: Cancer Research. 70, 21, p. 8264-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
An integrated genomic and epigenomic approach predicts therapeutic response to zebularine in human liver cancer
Andersen, Jesper Bøje, Factor, V. M., Marquardt, J. U., Raggi, C., Lee, Y., Seo, D., Conner, E. A. & Thorgeirsson, S. S., 20 Oct 2010, In: Science Translational Medicine. 2, 54, p. 54ra77Research output: Contribution to journal › Journal article › Research › peer-review
Progenitor-derived hepatocellular carcinoma model in the rat
Andersen, Jesper Bøje, Loi, R., Perra, A., Factor, V. M., Ledda-Columbano, G. M., Columbano, A. & Thorgeirsson, S. S., Apr 2010, In: Hepatology. 51, 4, p. 1401-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Loss of c-Met disrupts gene expression program required for G2/M progression during liver regeneration in mice
Factor, V. M., Seo, D., Ishikawa, T., Kaposi-Novak, P., Marquardt, J. U., Andersen, Jesper Bøje, Conner, E. A. & Thorgeirsson, S. S., 2010, In: PLOS ONE. 5, 9Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties
Coulouarn, C., Factor, V. M., Andersen, Jesper Bøje, Durkin, M. E. & Thorgeirsson, S. S., 8 Oct 2009, In: Oncogene. 28, 40, p. 3526-36 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Ribosomal protein mRNAs are primary targets of regulation in RNase-L-induced senescence
Andersen, Jesper Bøje, Mazan-Mamczarz, K., Zhan, M., Gorospe, M. & Hassel, B. A., 2009, In: RNA Biology. 6, 3, p. 305-15 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
UBE1L causes lung cancer growth suppression by targeting cyclin D1
Feng, Q., Sekula, D., Guo, Y., Liu, X., Black, C. C., Galimberti, F., Shah, S. J., Sempere, L. F., Memoli, V., Andersen, Jesper Bøje, Hassel, B. A., Dragnev, K. & Dmitrovsky, E., Dec 2008, In: Molecular Cancer Therapeutics. 7, 12, p. 3780-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
Role of 2-5A-dependent RNase-L in senescence and longevity
Andersen, Jesper Bøje, Li, X. L., Judge, C. S., Zhou, A., Jha, B. K., Shelby, S., Zhou, L., Silverman, R. H. & Hassel, B. A., 10 May 2007, In: Oncogene. 26, 21, p. 3081-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Post-transcriptional regulation of RNase-L expression is mediated by the 3'-untranslated region of its mRNA
Li, X., Andersen, Jesper Bøje, Ezelle, H. J., Wilson, G. M. & Hassel, B. A., 16 Mar 2007, In: The Journal of Biological Chemistry. 282, 11, p. 7950-60 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
The interferon regulated ubiquitin-like protein, ISG15, in tumorigenesis: friend or foe?
Andersen, Jesper Bøje & Hassel, B. A., Dec 2006, In: Cytokine & Growth Factor Reviews. 17, 6, p. 411-21 11 p.Research output: Contribution to journal › Review › Research › peer-review
Stage-associated overexpression of the ubiquitin-like protein, ISG15, in bladder cancer
Andersen, Jesper Bøje, Aaboe, M., Borden, E. C., Goloubeva, O. G., Hassel, B. A. & Orntoft, T. F., 22 May 2006, In: B J C. 94, 10, p. 1465-71 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
Interaction between the 2'-5' oligoadenylate synthetase-like protein p59 OASL and the transcriptional repressor methyl CpG-binding protein 1
Andersen, Jesper Bøje, Strandbygård, D. J., Hartmann, R. & Justesen, J., Feb 2004, In: European Journal of Biochemistry. 271, 3, p. 628-36 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 93714085
Most downloads
-
714
downloads
Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles - correction
Research output: Contribution to journal › Comment/debate › Research › peer-review
Published -
574
downloads
A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
194
downloads
MIR21 drives resistance to Heat Shock Protein 90 inhibition in cholangiocarcinoma
Research output: Contribution to journal › Journal article › Research › peer-review
Published