Kim Theilgaard-Mønch

Kim Theilgaard-Mønch

Clinical Associate Professor, Group leader

Member of:

    ORCID: 0000-0002-4239-4939

    Publication year:
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    1 - 25 out of 69Page size: 25
    1. 2024
    2. Published

      Dose-reduction trials in oncology — aiming for less toxicity and better quality of life at lower costs

      Theilgaard-Mønch, Kim & Ehlers, L. H., 2024, In: Nature Reviews Clinical Oncology. 21, p. 81-82

      Research output: Contribution to journal › Comment/debate › Research

    3. Submitted

      Therapeutic inhibition of DNA-Damage Response and PI3K/AKT signaling in Acute Myleoid Leukemia: A novel therapeutic strategy to boost chemotherapy response and overcome resistance

      Theilgaard-Mønch, Kim, 2024, (Submitted) In: J Cell Immunol.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. 2023
    5. Published

      Erythroid/megakaryocytic differentiation confers BCL-XL dependency and venetoclax resistance in acute myeloid leukemia

      Kuusanmäki, H., Dufva, O., Vähä-Koskela, M., Leppä, A-M., Huuhtanen, J., Vänttinen, I. M., Nygren, P. J., Klievink, J., Bouhlal, J. O. V., Pölönen, P., Zhang, Q., Adnan Awad, S., Mancebo-Pérez, C., Saad, J., Miettinen, J. J., Javarappa, K. K., Aakko, S., Ruokoranta, T., Eldfors, S., Heinäniemi, M. & 9 others, Theilgaard-Mønch, Kim, Wartiovaara-Kautto, U., Keränen, M. A. I., Porkka, K., Konopleva, M., Wennerberg, Krister, Kontro, M., Heckman, C. A. & Mustjoki, S., 2023, In: Blood. 141, 13, p. 1610-1625

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      The histone demethylase KDM5C functions as a tumor suppressor in AML by repression of bivalently marked immature genes

      Trempenau, M. L., Schuster, Mikkel Bruhn, Pundhir, Sachin, Araújo Pereira, Mafalda, Kalvisa, A., Tapia, Marta Cecylia, Su, Jinyu, Ge, Y., de Boer, Bauke, Balhuizen, Alexander, Bagger, F. O., Shliaha, P., Sroczynska, P., Walfridsson, J., Grønbæk, Kirsten, Theilgaard-Mønch, Kim, Jensen, O. N., Helin, K. & Porse, Bo Torben, 2023, In: Leukemia. 37, 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Trends in survival and cure after allogeneic haematopoietic cell transplantation for acute myeloid leukaemia from 2000 to 2020: A Danish population-based cohort study

      Gjærde, L. K., Jakobsen, L. H., Juhl-Christensen, C., Olesen, G., Petruskevicius, I., Severinsen, M. T., Marcher, C. W., Theilgaard-Mønch, Kim, Andersen, N. S., Friis, L. S., Kornblit, B., Petersen, S. L., Schjødt, I. & Sengeløv, Henrik, 2023, In: British Journal of Haematology. 200, 4, p. e40-e43

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    8. 2022
    9. Published

      Effects of chemotherapy dose reductions in overweight patients with acute myeloid leukaemia: A Danish nationwide cohort study

      Kristensen, D. T., Nielsen, L. B., Jakobsen, L. H. K., Kristensen, T. C., Jepsen, L. Ø., Schöllkopf, C., Theilgaard-Mønch, Kim, El-Galaly, T. C., Roug, A. S. & Severinsen, M. T., 2022, In: British Journal of Haematology. 199, p. 539-548 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Inhibition of oxidized nucleotide sanitation by TH1579 and conventional chemotherapy cooperatively enhance oxidative DNA-damage and survival in AML

      Centio, A., Estruch Alrich, Montserrat, Reckzeh, K., Sanjiv, K., Vittori, Camilla, Engelhard, Sophia Manon Charlotte, Warpman Berglund, U., Helleday, T. & Theilgaard-Mønch, Kim, 2022, In: Molecular Cancer Therapeutics. p. 703-714

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Phosphorylation of SHP2 at Tyr62 enables acquired resistance to SHP2 allosteric inhibitors in FLT3-ITD-driven AML

      Pfeiffer, A., Franciosa, Giulia, Locard-Paulet, Marie, Piga, I., Reckzeh, K., Vemulapalli, V., Blacklow, S. C., Theilgaard-Mønch, Kim, Jensen, Lars Juhl & Olsen, Jesper Velgaard, 2022, In: Cancer Research. 82, 11, p. 2141-2155 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Psychotropic Drug Use in Acute Myeloid Leukaemia (AML) and Myelodysplastic Syndrome (MDS): A Danish Nationwide Matched Cohort Study of 2404 AML and 1307 MDS Patients

      Jensen, O., Øvlisen, A. K., Jakobsen, L. H., Roug, A. S., Nielsen, R. E., Marcher, C. W., Ebbesen, L. H., Theilgaard-Mønch, Kim, Møller, P., Schöllkopf, C., Torp-Pedersen, Christian, El-Galaly, T. C. & Severinsen, M. T., 2022, In: Clinical Epidemiology. 14, p. 225-237 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      TET2 deficiency cooperates with CBFB-MYH11 to induce acute myeloid leukaemia and represents an early leukaemogenic event

      Reckzeh, K., Estruch Alrich, Montserrat, Ali, M., Helbo, A. S., Mosbech, A., Won, K. J., Rücker, F., Döhner, K. & Theilgaard-Mønch, Kim, 2022, In: British Journal of Haematology. 197, 2, p. 201-206

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Transcription factor-driven coordination of cell cycle exit and lineage-specification in vivo during granulocytic differentiation: In memoriam Professor Niels Borregaard

      Theilgaard-Mønch, Kim, Pundhir, Sachin, Reckzeh, K., Su, Jinyu, Tapia, Marta Cecylia, Furtwängler, Benjamin, Jendholm, J., Jakobsen, J. S., Hasemann, M. S., Knudsen, K. J., Cowland, J. B., Fossum, A., Schoof, E., Schuster, Mikkel Bruhn & Porse, Bo Torben, 2022, In: Nature Communications. 13, 1, 17 p., 3595.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. 2021
    16. Published

      MTH1 Inhibitor TH1579 Induces Oxidative DNA Damage and Mitotic Arrest in Acute Myeloid Leukemia

      Sanjiv, K., Calderón-Montaño, J. M., Pham, T. M., Erkers, T., Tsuber, V., Almlöf, I., Höglund, A., Heshmati, Y., Seashore-Ludlow, B., Nagesh Danda, A., Gad, H., Wiita, E., Göktürk, C., Rasti, A., Friedrich, S., Centio, A., Estruch, M., Våtsveen, T. K., Struyf, N., Visnes, T. & 12 others, Scobie, M., Koolmeister, T., Henriksson, M., Wallner, O., Sandvall, T., Lehmann, S., Theilgaard-Mønch, Kim, Garnett, M. J., Östling, P., Walfridsson, J., Helleday, T. & Warpman Berglund, U., 2021, In: Cancer Research. 81, 22, p. 5733-5744 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Novel Combination Treatments for AML

      Estruch Alrich, Montserrat, Vittori, Camilla, Muñoz-Montesinos, T., Reckzeh, K. & Theilgaard-Mønch, Kim, 2021, In: Journal of Cellular Immunology. 3, 4, 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Targeted inhibition of cooperative mutation- and therapy-induced AKT activation in AML effectively enhances response to chemotherapy

      Estruch Alrich, Montserrat, Reckzeh, K., Vittori, Camilla, Centio, A., Ali, M., Engelhard, Sophia Manon Charlotte, Zhao, L., Won, K. J., Liu, P., Porse, Bo Torben & Theilgaard-Mønch, Kim, 2021, In: Leukemia. 35, p. 2030-2042

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Targeting of PI3K/AKT signaling and DNA damage response in acute myeloid leukemia: a novel therapeutic strategy to boost chemotherapy response and overcome resistance

      Estruch Alrich, Montserrat, Vittori, Camilla, Montesinos, T. M., Reckzeh, K. & Theilgaard-Mønch, Kim, 2021, In: Cancer Drug Resistance. 4, p. 984-995

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Temporal changes in survival among adult patients with acute myeloid leukaemia in the period 2000-2016: a Danish population-based study

      Hjort Jakobsen, L., Stidsholt Roug, A., Kiesbye Øvlisen, A., Werenberg Marcher, C., Beier Ommen, H., Theilgaard-Mønch, Kim, Møller, P., Schöllkopf, C., Kristensen, D., Maria Henriette Naur, T., Bøgsted, M., Christoffer El-Galaly, T. & Tang Severinsen, M., 2021, In: British Journal of Haematology. 193, 3, p. 482-487 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      The eha research roadmap: normal hematopoiesis

      Jaffredo, T., Balduini, A., Bigas, A., Bernardi, R., Bonnet, D., Canque, B., Charbord, P., Cumano, A., Delwel, R., Durand, C., Fibbe, W., Forrester, L., De Franceschi, L., Ghevaert, C., Gjertsen, B., Gottgens, B., Graf, T., Heidenreich, O., Hermine, O., Higgs, D. & 21 others, Kleanthous, M., Klump, H., Kouskoff, V., Krause, D., Lacaud, G., Lo Celso, C., Martens, J. H. A., Méndez-Ferrer, S., Menendez, P., Oostendorp, R., Philipsen, S., Porse, Bo Torben, Raaijmakers, M., Robin, C., Stunnenberg, H., Theilgaard-Mønch, Kim, Touw, I., Vainchenker, W., Corrons, J. L. V., Yvernogeau, L. & Schuringa, J. J., 2021, In: HemaSphere. 5, 12, e669.

      Research output: Contribution to journal › Review › Research › peer-review

    22. Published

      The prognostic impact of anthropometrics in acute myeloid leukemia treated with intensive chemotherapy - A Danish nationwide cohort study

      Kristensen, D., Nielsen, L. B., Roug, A. S., Kristensen, T. C., Heath, A., Jacobsen, L. H., Nørgaard, J. M., Jepsen, L. Ø., Schöllkopf, C., Theilgaard-Mønch, Kim & Severinsen, M. T., 2021, In: Leukemia Research. 106, 106567.

      Research output: Contribution to journal › Comment/debate › Research

    23. Published

      Treatment intensity and survival trends among real-world elderly AML patients diagnosed in the period 2001-2016: a Danish nationwide cohort study

      Naur, T. M. H., Jakobsen, L. H., Roug, A. S., El-Galaly, T. C., Marcher, C. W., Nørgaard, J. M., Theilgaard-Mønch, Kim, Møller, Peter, Schöllkopf, C. & Severinsen, M. T., 2021, In: Leukemia and Lymphoma. 62, 8, p. 2014-2017 4 p.

      Research output: Contribution to journal › Letter › Research › peer-review

    24. 2020

    25. The prognostic effect of smoking status on intensively treated acute myeloid leukaemia - A Danish nationwide cohort study

      Kristensen, D., Nielsen, L. B., Roug, A. S., Kristensen, T. C., El-Galaly, T. C., Nørgaard, J. M., Marcher, C. W., Schöllkopf, C., Theilgaard-Mønch, Kim & Severinsen, M. T., Jul 2020, In: British Journal of Haematology. 190, 2, p. 236-243

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. 2019
    27. Published

      Identification of two distinct pathways of human myelopoiesis

      Drissen, R., Thongjuea, S., Theilgaard-Mønch, Kim & Nerlov, C., 2019, In: Science immunology. 4, 35, eaau7148.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Mutant CEBPA directly drives the expression of the targetable tumor-promoting factor CD73 in AML

      Jakobsen, J. S., Laursen, L. G., Schuster, Mikkel Bruhn, Pundhir, Sachin, Schoof, E., Ge, Y., d'Altri, T., Vitting-Seerup, K., Rapin, N., Gentil, C., Jendholm, J., Theilgaard-Mønch, Kim, Reckzeh, K., Bullinger, L., Döhner, K., Hokland, P., Fitzgibbon, J. & Porse, Bo Torben, 2019, In: Science Advances. 5, 7, p. 1-16 16 p., eaaw4304.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. 2018
    30. Published

      Human adult HSCs can be discriminated from lineage-committed HPCs by the expression of endomucin

      Reckzeh, K., Kizilkaya, Hüsün Sheyma, Helbo, A. S., Estruch Alrich, Montserrat, Deslauriers, A. G., Grover, A., Rapin, N., Asmar, F., Grønbæk, Kirsten, Porse, Bo Torben, Borregaard, N., Vestweber, D., Nerlov, C. & Theilgaard-Mønch, Kim, 2018, In: Blood advances. 2, 13, p. 1628-1632 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. 2017
    32. Published

      Gut microbiota sustains hematopoiesis

      Theilgaard-Mønch, Kim, 9 Feb 2017, In: Blood. 129, 6, p. 662-663 2 p.

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    33. 2016
    34. Published

      Low-molecular-weight carbohydrate Pentaisomaltose may replace dimethyl sulfoxide as a safer cryoprotectant for cryopreservation of peripheral blood stem cells

      Svalgaard, J. D., Haastrup, E. K., Reckzeh, K., Holst, B., Glovinski, P. V., Gørløv, J. S., Hansen, Morten Bagge, Theilgaard-Mønch, Kim, Clausen, C. & Fischer-Nielsen, A., May 2016, In: Transfusion. 56, 5, p. 1088-95 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 3997971