Mikkel Bruhn Schuster

Mikkel Bruhn Schuster

Senior researcher

ORCID: 0000-0003-1742-5550

Publication year:
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1 - 22 out of 22Page size: 500
  1. 2023
  2. Published

    TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression

    Heyes, E., Wilhelmson, Anna, Wenzel, Anne, Manhart, G., Eder, T., Schuster, Mikkel Bruhn, Rzepa, E., Pundhir, Sachin, D’Altri, T., Frank, Anne-Katrine, Gentil, C., Woessmann, J., Schoof, E. M., Meggendorfer, M., Schwaller, J., Haferlach, T., Grebien, F. & Porse, Bo Torben, 2023, In: Nature Communications. 14, 18 p., 6185.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    The histone demethylase KDM5C functions as a tumor suppressor in AML by repression of bivalently marked immature genes

    Trempenau, M. L., Schuster, Mikkel Bruhn, Pundhir, Sachin, Araújo Pereira, Mafalda, Kalvisa, A., Tapia, Marta Cecylia, Su, Jinyu, Ge, Y., de Boer, Bauke, Balhuizen, Alexander, Bagger, F. O., Shliaha, P., Sroczynska, P., Walfridsson, J., Grønbæk, Kirsten, Theilgaard-Mønch, Kim, Jensen, O. N., Helin, K. & Porse, Bo Torben, 2023, In: Leukemia. 37, 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. 2022
  5. Published

    H3K9 dimethylation safeguards cancer cells against activation of the interferon pathway

    Hansen, A. M., Ge, Y., Schuster, Mikkel Bruhn, Pundhir, Sachin, Jakobsen, J. S., Kalvisa, A., Tapia, Marta Cecylia, Gordon, Sandra, Ambri, F., Bagger, F. O., Pandey, D., Helin, K. & Porse, Bo Torben, 2022, In: Science Advances. 8, 11, eabf8627.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    PTBP1 promotes hematopoietic stem cell maintenance and red blood cell development by ensuring sufficient availability of ribosomal constituents

    Rehn, M., Wenzel, Anne, Frank, Anne-Katrine, Schuster, Mikkel Bruhn, Pundhir, Sachin, Jørgensen, N., Vitting-Seerup, K., Ge, Y., Jendholm, J., Michaut, Magali, Schoof, E. M., Jensen, T. L., Rapin, N., Sapio, R. T., Andersen, Kasper Langebjerg, Lund, Anders H., Solimena, M., Holzenberger, M., Pestov, D. G. & Porse, Bo Torben, 2022, In: Cell Reports. 39, 6, 28 p., 110793.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Transcription factor-driven coordination of cell cycle exit and lineage-specification in vivo during granulocytic differentiation: In memoriam Professor Niels Borregaard

    Theilgaard-Mønch, Kim, Pundhir, Sachin, Reckzeh, K., Su, Jinyu, Tapia, Marta Cecylia, Furtwängler, Benjamin, Jendholm, J., Jakobsen, J. S., Hasemann, M. S., Knudsen, K. J., Cowland, J. B., Fossum, A., Schoof, E., Schuster, Mikkel Bruhn & Porse, Bo Torben, 2022, In: Nature Communications. 13, 1, 17 p., 3595.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. 2021
  9. Published

    The ASXL1-G643W variant accelerates the development of CEBPA mutant acute myeloid leukemia

    D'Altri, T., Wilhelmson, Anna, Schuster, Mikkel Bruhn, Wenzel, Anne, Kalvisa, A., Pundhir, Sachin, Hansen, A. M. & Porse, Bo Torben, 2021, In: Haematologica. 106, 4, p. 1000-1007 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. 2019
  11. Published

    Heterozygous loss of Srp72 in mice is not associated with major hematological phenotypes

    D'Altri, T., Schuster, Mikkel Bruhn, Wenzel, Anne & Porse, Bo Torben, 2019, In: European Journal of Haematology. 103, 4, p. 319-328 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Mutant CEBPA directly drives the expression of the targetable tumor-promoting factor CD73 in AML

    Jakobsen, J. S., Laursen, L. G., Schuster, Mikkel Bruhn, Pundhir, Sachin, Schoof, E., Ge, Y., d'Altri, T., Vitting-Seerup, K., Rapin, N., Gentil, C., Jendholm, J., Theilgaard-Mønch, Kim, Reckzeh, K., Bullinger, L., Döhner, K., Hokland, P., Fitzgibbon, J. & Porse, Bo Torben, 2019, In: Science Advances. 5, 7, p. 1-16 16 p., eaaw4304.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    The splicing factor RBM25 controls MYC activity in acute myeloid leukemia

    Ge, Y., Schuster, Mikkel Bruhn, Pundhir, Sachin, Rapin, N., Bagger, F. O., Sidiropoulos, N., Hashem, N. & Porse, Bo Torben, 2019, In: Nature Communications. 10, 1, p. 1-14 14 p., 172.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. 2018
  15. Published

    Enhancer and Transcription Factor Dynamics during Myeloid Differentiation Reveal an Early Differentiation Block in Cebpa null Progenitors

    Pundhir, Sachin, Bratt Lauridsen, F. K., Schuster, Mikkel Bruhn, Jakobsen, J. S., Ge, Y., Schoof, E. M., Rapin, N. P. J., Waage, J., Hasemann, M. S. & Porse, Bo Torben, 2018, In: Cell Reports. 23, 9, p. 2744-2757 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. 2016
  17. Published

    The multifaceted functions of C/EBPα in normal and malignant haematopoiesis

    Ohlsson, E., Schuster, Mikkel Bruhn, Hasemann, M. & Porse, Bo Torben, Apr 2016, In: Leukemia. 30, 4, p. 767-75 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  18. 2015
  19. Published

    Amplification of pico-scale DNA mediated by bacterial carrier DNA for small-cell-number transcription factor ChIP-seq

    Jakobsen, J. S., Bagger, F. O., Hasemann, M. S., Schuster, Mikkel Bruhn, Frank, Anne-Katrine, Waage, J., Vitting-Seerup, K. & Porse, Bo Torben, 2015, In: BMC Genomics. 16, p. 46

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. 2014
  21. Published

    shRNA screening identifies JMJD1C as being required for leukemia maintenance

    Sroczynska, P., Cruickshank, V. A., Bukowski, J., Miyagi, S., Bagger, F. O., Walfridsson, J., Schuster, Mikkel Bruhn, Porse, Bo Torben & Helin, K., 5 Feb 2014, In: Blood (online).

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    C/EBPα Is Required for Long-Term Self-Renewal and Lineage Priming of Hematopoietic Stem Cells and for the Maintenance of Epigenetic Configurations in Multipotent Progenitors

    Hasemann, M. S., Lauridsen, F. K. B., Waage, J., Jakobsen, J. S., Frank, Anne-Katrine, Schuster, Mikkel Bruhn, Rapin, N. P. J., Bagger, F. O., Hoppe, P. S., Schroeder, T. & Porse, Bo Torben, Jan 2014, In: P L o S Genetics (Online). 10, 1, p. 1-10 10 p., e1004079.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. 2013
  24. Published

    Lack of the p42 form of C/EBPα leads to spontaneous immortalization and lineage infidelity of committed myeloid progenitors

    Schuster, Mikkel Bruhn, Frank, Anne-Katrine, Bagger, F. O., Rapin, N., Vikesaa, J. & Porse, Bo Torben, Oct 2013, In: Experimental Hematology. 41, 10, p. 882-893 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. 2012
  26. Published

    Phosphorylation of Serine 248 of C/EBPa Is Dispensable for Myelopoiesis but Its Disruption Leads to a Low Penetrant Myeloid Disorder with Long Latency

    Hasemann, M. S., Schuster, Mikkel Bruhn, Frank, Anne-Katrine, Theilgaard-Mønch, Kim, Pedersen, T. Å., Nerlov, C. & Porse, Bo Torben, 2012, In: P L o S One. 7, 6, p. e38841

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. 2009
  28. Published

    C/EBPalpha in leukemogenesis: Identity and origin of the leukemia-initiating cell

    Schuster, Mikkel Bruhn & Porse, Bo Torben, 2009, In: BioFactors. 35, 3, p. 227-31 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. 2008
  30. Published

    Modeling of C/EBPalpha mutant acute myeloid leukemia reveals a common expression signature of committed myeloid leukemia-initiating cells.

    Kirstetter, P., Schuster, Mikkel Bruhn, Bereshchenko, O., Moore, S., Dvinge, H., Kurz, E., Theilgaard-Mønch, Kim, Månsson, R., Pedersen, T. A., Pabst, T., Schrock, E., Porse, Bo Torben, Jacobsen, S. E. W., Bertone, P., Tenen, D. G. & Nerlov, C., 2008, In: Cancer Cell. 13, 4, p. 299-310 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Mutation of C/EBPalpha predisposes to the development of myeloid leukemia in a retroviral insertional mutagenesis screen.

    Hasemann, M. S., Damgaard, I., Schuster, Mikkel Bruhn, Theilgaard-Mønch, Kim, Sørensen, A. B., Mrsic, A., Krugers, T., Ylstra, B., Pedersen, F. S., Nerlov, C. & Porse, Bo Torben, 2008, In: Blood. 111, 8, p. 4309-21 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. 2006
  33. Published

    C/EBPalpha: a tumour suppressor in multiple tissues?

    Schuster, Mikkel Bruhn & Porse, Bo Torben, 2006, In: BBA General Subjects. 1766, 1, p. 88-103 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    The proline-histidine-rich CDK2/CDK4 interaction region of C/EBPalpha is dispensable for C/EBPalpha-mediated growth regulation in vivo.

    Porse, Bo Torben, Pedersen, T. A., Hasemann, M. S., Schuster, Mikkel Bruhn, Kirstetter, P., Luedde, T., Damgaard, I., Kurz, E., Schjerling, C. K. & Nerlov, C., 2006, In: Molecular and Cellular Biology. 26, 3, p. 1028-37 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. 2003
  36. Published

    Transgene mus som sygdomsmodeller.

    Schuster, Mikkel Bruhn & Porse, Bo Torben, 2003, In: Ugeskrift for læger. 165, 8, p. 793-6 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

ID: 4006061