Niels Behrendt

Niels Behrendt

Clinical Professor

Member of:

  • Clinical Oncology


  1. 2023
  2. Published

    Optical coherence tomography for presurgical delineation of basal cell carcinomas on the face—A comparison with histopathology

    Holm, Kirsten, Nielsen, L. J., Lock-Andersen, J., Behrendt, Niels, Svensson, M. S., Themstrup, L. & Jemec, Gregor, 2023, In: Journal of Cutaneous Pathology. 50, 5, p. 441-449 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Targeted delivery of alcohol-containing payloads with antibody-drug conjugates

    Grier, K. E., Hansen, A. H., Haxvig, C. S., Li, Xin, Krigslund, O., Behrendt, Niels, Engelholm, Lars Henning, Rossi, F., Sousa, B. C., Harradence, G. J., Camper, N. & Qvortrup, K. M., 2023, In: Chemical Communications. 59, 47, p. 7240-7242

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2022
  5. Published

    The endocytic receptor uPARAP is a regulator of extracellular thrombospondin-1

    Nørregaard, Kirstine Sandal, Jürgensen, Henrik Jessen, Ingvarsen, S. Z., Heltberg, S. S., Hagensen, C. E., Gårdsvoll, Henrik, Madsen, D. H., Jensen, O. N., Engelholm, Lars Henning & Behrendt, Niels, 2022, In: Matrix Biology. 111, p. 307-328 22 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Uncovering mediators of collagen degradation in the tumor microenvironment

    Thorseth, M. L., Carretta, M., Jensen, C., Mølgaard, K., Jürgensen, Henrik Jessen, Engelholm, Lars Henning, Behrendt, Niels, Willumsen, N. & Madsen, Daniel Hargbøl, 2022, In: Matrix Biology Plus. 13, 100101.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2021
  8. Published

    Osteosarcoma and metastasis associated bone degradation—a tale of osteoclast and malignant cell cooperativity

    Nørregaard, Kirstine Sandal, Jürgensen, Henrik Jessen, Gårdsvoll, Henrik, Engelholm, Lars Henning, Behrendt, Niels & Søe, K., 2021, In: International Journal of Molecular Sciences. 22, 13, 6865.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The Collagen Receptor uPARAP in Malignant Mesothelioma: A Potential Diagnostic Marker and Therapeutic Target

    Cakilkaya, Pinar, Sørensen, R. R., Jürgensen, Henrik Jessen, Krigslund, O., Gårdsvoll, Henrik, Nielsen, C. F., Santoni Rugiu, Eric, Behrendt, Niels & Engelholm, Lars Henning, 2021, In: International Journal of Molecular Sciences. 22, 21, 17 p., 11452.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2020
  11. Published

    Cellular uptake of collagens and implications for immune cell regulation in disease

    Jürgensen, Henrik Jessen, van Putten, Sander Maarten, Nørregaard, Kirstine Sandal, Bugge, T. H., Engelholm, Lars Henning, Behrendt, Niels & Madsen, D. H., 2020, In: Cellular and Molecular Life Sciences. 77, 16, p. 3161-3176

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    The collagen receptor uPARAP/Endo180 regulates collectins through unique structural elements in its FNII domain

    Nørregaard, Kirstine Sandal, Krigslund, O., Behrendt, Niels, Engelholm, Lars Henning & Jürgensen, Henrik Jessen, 2020, In: Journal of Biological Chemistry. 295, 27, p. 9157-9170 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Tumor cell MT1-MMP is dispensable for osteosarcoma tumor growth, bone degradation and lung metastasis

    Ingvarsen, S. Z., Gårdsvoll, Henrik, van Putten, Sander Maarten, Nørregaard, Kirstine Sandal, Krigslund, O., Meilstrup, Josephine Amalie, Tran, C., Jürgensen, Henrik Jessen, Melander, M. C., Nielsen, Carsten Haagen, Kjær, Andreas, Bugge, T. H., Engelholm, Lars Henning & Behrendt, Niels, 2020, In: Scientific Reports. 10, 1, p. 1-16 19138.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2019
  15. Published

    Immune regulation by fibroblasts in tissue injury depends on uPARAP-mediated uptake of collectins

    Jürgensen, Henrik Jessen, Nørregaard, Kirstine Sandal, Sibree, M. M., Santoni Rugiu, Eric, Madsen, Daniel Hargbøl, Wassilew, K., Krustrup, D., Garred, Peter, Bugge, T. H., Engelholm, Lars Henning & Behrendt, Niels, 1 Jan 2019, In: Journal of Cell Biology. 218, 1, p. 333-349 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    TAFI deficiency causes maladaptive vascular remodeling after hemophilic joint bleeding

    Wyseure, T., Yang, T., Zhou, J. Y., Cooke, E. J., Wanko, B., Olmer, M., Agashe, R., Morodomi, Y., Behrendt, Niels, Lotz, M., Morser, J., von Drygalski, A. & Mosnier, L. O., 1 Jan 2019, In: JCI Insight. 4, 19, p. 1-19 e128379.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    CCL2/MCP-1 signaling drives extracellular matrix turnover by diverse macrophage subsets

    Jürgensen, Henrik Jessen, Silva, L. M., Krigslund, O., Van Putten, S., Madsen, D. H., Behrendt, Niels, Engelholm, Lars Henning & Bugge, T. H., 2019, In: Matrix Biology Plus. 1, p. 1-20 100003.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. 2018
  19. Published

    uPARAP/Endo180 receptor is a gatekeeper of VEGFR-2/VEGFR-3 heterodimerisation during pathological lymphangiogenesis

    Durré, T., Morfoisse, F., Erpicum, C., Ebroin, M., Blacher, S., García-Caballero, M., Deroanne, C., Louis, T., Balsat, C., Van de Velde, M., Kaijalainen, S., Kridelka, F., Engelholm, Lars Henning, Struman, I., Alitalo, K., Behrendt, Niels, Paupert, J. & Noel, A., 5 Dec 2018, In: Nature Communications. 9, 1, p. 1-16 5178.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Defective TAFI activation in hemophilia a mice is a major contributor to joint bleeding

    Wyseure, T., Cooke, E. J., Declerck, P. J., Behrendt, Niels, Meijers, J. C. M., Von Drygalski, A. & Mosnier, L. O., 2018, In: Blood. 132, 15, p. 1593-1603 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2017
  22. Published

    Tumor-Associated Macrophages Derived from Circulating Inflammatory Monocytes Degrade Collagen through Cellular Uptake

    Madsen, Daniel Hargbøl, Jürgensen, Henrik Jessen, Siersbæk, M. S., Kuczek, D. E., Grey Cloud, L., Liu, S., Behrendt, Niels, Grøntved, L., Weigert, R. & Bugge, T. H., 26 Dec 2017, In: Cell Reports. 21, 13, p. 3662-3671 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Phagocytosis of Collagen Fibrils by Fibroblasts In Vivo is Independent of the uPARAP/Endo180 Receptor

    Sprangers, S., Behrendt, Niels, Engelholm, Lars Henning, Cao, Y. & Everts, V., Jun 2017, In: Journal of Cellular Biochemistry. 118, 6, p. 1590-1595

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    The collagen receptor uPARAP/Endo180 as a novel target for antibody-drug conjugate mediated treatment of mesenchymal and leukemic cancers

    Nielsen, C. F., van Putten, S. M., Lund, I. K., Melander, M. C., Nørregaard, Kirstine Sandal, Jürgensen, Henrik Jessen, Reckzeh, K., Christensen, K. R., Ingvarsen, S. Z., Gårdsvoll, Henrik, Jensen, K. E., Hamerlik, P., Engelholm, Lars Henning & Behrendt, Niels, 2017, In: OncoTarget. 8, 27, p. 44605-44624 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. 2016
  26. Published

    Crystal structures of the ligand-binding region of uPARAP: effect of calcium ion binding

    Yuan, C., Jürgensen, Henrik Jessen, Engelholm, Lars Henning, Li, R., Liu, M., Jiang, L., Luo, Z., Behrendt, Niels & Huang, M., 1 Aug 2016, In: Biochemical Journal. 473, 15, p. 2359-68 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Targeting a novel bone degradation pathway in primary bone cancer by inactivation of the collagen receptor uPARAP/Endo180

    Engelholm, Lars Henning, Carlsen Melander, E. M., Hald, A., Persson, M., Madsen, D. H., Jürgensen, Henrik Jessen, Johansson, K., Nielsen, C., Nørregaard, Kirstine Sandal, Ingvarsen, S. Z., Kjær, Andreas, Trovik, C. S., Lærum, O. D., Bugge, T. H., Eide, J. & Behrendt, Niels, Jan 2016, In: Journal of Pathology. 238, 1, p. 120-33 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 2015
  29. Published

    The collagen receptor uPARAP/Endo180 in tissue degradation and cancer (Review)

    Carlsen Melander, E. M., Jürgensen, Henrik Jessen, Madsen, Daniel Hargbøl, Engelholm, Lars Henning & Behrendt, Niels, Oct 2015, In: International Journal of Oncology. 47, 4, p. 1177-88 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. 2014
  31. Published

    Advances in targeted delivery of small interfering RNA using simple bioconjugates

    Nielsen, C., Kjems, J., Sørensen, K. R., Engelholm, Lars Henning & Behrendt, Niels, 2014, In: Expert Opinion on Drug Delivery. 11, 5, p. 791-822 32 p.

    Research output: Contribution to journalReviewResearchpeer-review

  32. Published

    Complex Determinants in Specific Members of the Mannose Receptor Family Govern Collagen Endocytosis

    Jürgensen, Henrik Jessen, Johansson, K., Madsen, D. H., Porse, A., Melander, M. C., Sørensen, K. R., Nielsen, C., Bugge, T. H., Behrendt, Niels & Engelholm, Lars Henning, 2014, In: The Journal of Biological Chemistry. 289, 11, p. 7935-7947 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Matrix metalloproteinase 2 and membrane type 1 matrix metalloproteinase co-regulate axonal outgrowth of mouse retinal ganglion cells

    Gaublomme, D., Buyens, T., De Groef, L., Stakenborg, M., Janssens, E., Ingvarsen, S., Porse, A., Behrendt, Niels & Moons, L., 2014, In: Journal of Neurochemistry. 129, 6, p. 966-979 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. 2013
  35. Published

    A monoclonal antibody interferes with TIMP-2 binding and incapacitates the MMP-2-activating function of multifunctional, pro-tumorigenic MMP-14/MT1-MMP

    Shiryaev, S. A., Remacle, A. G., Golubkov, V. S., Ingvarsen, S., Porse, A., Behrendt, Niels, Cieplak, P. & Strongin, A. Y., 2 Dec 2013, In: Oncogenesis. 2, p. e80

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    M2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pathway

    Madsen, Daniel Hargbøl, Leonard, D., Masedunskas, A., Moyer, A., Jürgensen, Henrik Jessen, Peters, D. E., Amornphimoltham, P., Selvaraj, A., Yamada, S. S., Brenner, D. A., Burgdorf, S., Engelholm, Lars Henning, Behrendt, Niels, Holmbeck, K., Weigert, R. & Bugge, T. H., 16 Sep 2013, In: Journal of Cell Biology. 202, 6, p. 951-66 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Ficolin-1-PTX3 complex formation promotes clearance of altered self-cells and modulates IL-8 production

    Ma, Y. J., Doni, A., Romani, L., Jürgensen, Henrik Jessen, Behrendt, Niels, Mantovani, A. & Garred, Peter, 1 Aug 2013, In: Journal of immunology (Baltimore, Md. : 1950). 191, 3, p. 1324-33 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Targeting a single function of the multifunctional matrix metalloprotease MT1-MMP: impact on lymphangiogenesis

    Ingvarsen, S., Porse, A., Erpicum, C., Maertens, L., Jürgensen, H. J., Madsen, Daniel Hargbøl, Melander, M. C., Gårdsvoll, Henrik, Høyer-Hansen, G., Noel, A., Holmbeck, K., Engelholm, Lars Henning & Behrendt, Niels, 12 Apr 2013, In: Journal of Biological Chemistry. 288, 15, p. 10195-204 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Differential actions of the endocytic collagen receptor uPARAP/Endo180 and the collagenase MMP-2 in bone homeostasis

    Madsen, Daniel Hargbøl, Jürgensen, Henrik Jessen, Ingvarsen, S., Melander, M. C., Albrechtsen, Reidar, Hald, A., Holmbeck, K., Bugge, T. H., Behrendt, Niels & Engelholm, Lars Henning, 2013, In: PloS one. 8, 8, p. e71261

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. 2012
  41. Published

    Matrix Proteases in Health and Disease

    Behrendt, Niels, 24 Aug 2012, Wiley-VCH.

    Research output: Book/ReportBookResearchpeer-review

  42. Published

    Preface: Matrix Proteases in Health and Disease

    Behrendt, Niels, 24 Aug 2012, Matrix Proteases in Health and Disease. Wiley-VCH, p. xiii

    Research output: Chapter in Book/Report/Conference proceedingPreface/postscriptResearchpeer-review

  43. Published

    Endocytic collagen degradation: a novel mechanism involved in protection against liver fibrosis

    Madsen, D. H., Jürgensen, H. J., Ingvarsen, S. Z., Melander, M. C., Vainer, B., Egerod, Kristoffer Lihme, Hald, A., Rønø, B., Madsen, C. A., Bugge, T. H., Engelholm, L. H. & Behrendt, Niels, 2012, In: Journal of Pathology. 227, 1, p. 94-105 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Inhibitory Monoclonal Antibodies against Mouse Proteases Raised in Gene-Deficient Mice Block Proteolytic Functions in vivo

    Lund, I. K., Rasch, M. G., Ingvarsen, S., Pass, J., Madsen, Daniel Hargbøl, Engelholm, Lars Henning, Behrendt, Niels & Høyer-Hansen, G., 2012, In: Frontiers in Pharmacology. 3, p. 122

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    New and paradoxical roles of matrix metalloproteinases in the tumor microenvironment

    Noël, A., Gutiérrez-Fernández, A., Sounni, N. E., Behrendt, Niels, Maquoi, E., Lund, I. K., Cal, S., Hoyer-Hansen, G. & López-Otín, C., 2012, In: Frontiers in Pharmacology. 3, p. 140

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. 2011
  47. Published

    Conformational regulation of urokinase receptor function: impact of receptor occupancy and epitope-mapped monoclonal antibodies on lamellipodia induction

    Gårdsvoll, Henrik, Jacobsen, B., Kriegbaum, M. C., Behrendt, Niels, Engelholm, Lars Henning, Østergaard, S. & Ploug, Michael, 23 Sep 2011, In: The Journal of Biological Chemistry. 286, 38, p. 33544-56 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    The non-phagocytic route of collagen uptake: a distinct degradation pathway

    Madsen, Daniel Hargbøl, Ingvarsen, S., Jürgensen, Henrik Jessen, Melander, M. C., Kjøller, L., Moyer, A., Honoré, C., Madsen, M. C., Garred, Peter, Burgdorf, S., Bugge, T. H., Behrendt, Niels & Engelholm, Lars Henning, 29 Jul 2011, In: The Journal of Biological Chemistry. 286, 30, p. 26996-7010 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    A novel functional role of collagen glycosylation: interaction with the endocytic collagen receptor uPARAP/ENDO 180

    Jürgensen, Henrik Jessen, Madsen, Daniel Hargbøl, Ingvarsen, S., Melander, M. C., Gårdsvoll, Henrik, Patthy, L., Engelholm, Lars Henning & Behrendt, Niels, 2011, In: Journal of Biological Chemistry. 286, 37, p. 32736-48 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. 2009
  51. Published

    The collagen receptor uPARAP/Endo180

    Engelholm, Lars Henning, Ingvarsen, S., Jürgensen, Henrik Jessen, Hillig, T., Madsen, Daniel Hargbøl, Nielsen, B. S. & Behrendt, Niels, 1 Jan 2009, In: Frontiers in Bioscience. 14, p. 2103-14 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  52. Published

    MT1-MMP and type II collagen specify skeletal stem cells and their bone and cartilage progeny

    Szabova, L., Yamada, S. S., Wimer, H., Chrysovergis, K., Ingvarsen, S., Behrendt, Niels, Engelholm, L. H. & Holmbeck, K., 2009, In: Journal of Bone and Mineral Research. 24, 11, p. 1905-1916 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. 2008
  54. Published

    Antibody-mediated Targeting of the Urokinase-type Plasminogen Activator Proteolytic Function Neutralizes Fibrinolysis in Vivo

    Lund, I. K., Jögi, A., Rono, B., Rasch, M. G., Lund, L. R., Almholt, K., Gardsvoll, H., Behrendt, Niels, Romer, J. & Hoyer-Hansen, G., 21 Nov 2008, In: Journal of Biological Chemistry. 283, 47, p. 32506-32515

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    A composite role of vitronectin and urokinase in the modulation of cell morphology upon expression of the urokinase receptor

    Hillig, T., Engelholm, Lars Henning, Ingvarsen, S., Madsen, Daniel Hargbøl, Gårdsvoll, Henrik, Larsen, J. K., Ploug, Michael, Danø, K., Kjøller, L. & Behrendt, Niels, 30 May 2008, In: Journal of Biological Chemistry. 283, 22, p. 15217-15223 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Dimerization of endogenous MT1-MMP is a regulatory step in the activation of the 72-kDa gelatinase MMP-2 on fibroblasts and fibrosarcoma cells

    Ingvarsen, S. Z., Madsen, D. H., Hillig, T., Lund, L. R., Holmbeck, Kenn, Behrendt, Niels & Engelholm, L. H., 2008, In: Biological Chemistry. 389, 7, p. 943-953 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. 2007
  58. Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation

    Madsen, Daniel Hargbøl, Engelholm, Lars Henning, Ingvarsen, S., Hillig, T., Wagenaar-Miller, R. A., Kjøller, L., Gårdsvoll, Henrik, Høyer-Hansen, G., Holmbeck, Kenn, Bugge, T. H. & Behrendt, Niels, 14 Sep 2007, In: The Journal of Biological Chemistry. 282, 37, p. 27037-45 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Complementary roles of intracellular and pericellular collagen degradation pathways in vivo

    Wagenaar-Miller, R. A., Engelholm, Lars Henning, Gavard, J., Yamada, S. S., Gutkind, J. S., Behrendt, Niels, Bugge, T. H. & Holmbeck, Kenn, Sep 2007, In: Molecular and Cellular Biology. 27, 18, p. 6309-22 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Increased expression of the collagen internalization receptor uPARAP/Endo180 in the stroma of head and neck cancer

    Sulek, J., Wagenaar-Miller, R. A., Shireman, J., Molinolo, A., Madsen, Daniel Hargbøl, Engelholm, Lars Henning, Behrendt, Niels & Bugge, T. H., Apr 2007, In: Journal of Histochemistry and Cytochemistry. 55, 4, p. 347-53 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. 2005
  62. Intracellular collagen degradation mediated by uPARAP/Endo180 is a major pathway of extracellular matrix turnover during malignancy

    Curino, A. C., Engelholm, Lars Henning, Yamada, S. S., Holmbeck, K., Lund, L. R., Molinolo, A. A., Behrendt, Niels, Nielsen, B. S. & Bugge, T. H., 2005, In: Journal of Cell Biology. 169, 6, p. 977-985 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. 2004
  64. Published

    Cysteine-rich secretory protein 3 is a ligand of alpha1B-glycoprotein in human plasma

    Udby, L., Sørensen, O. E., Pass, J., Johnsen, A. H., Behrendt, Niels, Borregaard, N. & Kjeldsen, L., 12 Oct 2004, In: Biochemistry. 43, 40, p. 12877-86 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    uPARAP/endo180 directs lysosomal delivery and degradation of collagen IV

    Kjøller, L., Engelholm, Lars Henning, Høyer-Hansen, M., Danø, K., Bugge, T. H. & Behrendt, Niels, 1 Feb 2004, In: Experimental Cell Research. 293, 1, p. 106-16 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    The urokinase receptor (uPAR) and the uPAR-associated protein (uPARAP/Endo180): membrane proteins engaged in matrix turnover during tissue remodeling

    Behrendt, Niels, Feb 2004, In: Biological Chemistry. 385, 2, p. 103-36 34 p.

    Research output: Contribution to journalReviewResearchpeer-review

  67. 2003
  68. Published

    The pro-urokinase plasminogen-activation system in the presence of serpin-type inhibitors and the urokinase receptor: rescue of activity through reciprocal pro-enzyme activation

    Behrendt, Niels, List, K., Andreasen, P. A. & Danø, K., 15 Apr 2003, In: Biochemical Journal. 371, Pt 2, p. 277-87 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    uPARAP/Endo180 is essential for cellular uptake of collagen and promotes fibroblast collagen adhesion

    Engelholm, Lars Henning, List, K., Netzel-Arnett, S., Cukierman, E., Mitola, D. J., Aaronson, H., Kjøller, L., Larsen, J. K., Yamada, K. M., Strickland, D. K., Holmbeck, Kenn, Danø, K., Birkedal-Hansen, H., Behrendt, Niels & Bugge, T. H., 31 Mar 2003, In: Journal of Cell Biology. 160, 7, p. 1009-15 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Urokinase-type plasminogen activator receptor

    Dano, K., Blasi, F., Roldan, Ann, L., Cubellis, Maria, V., Masucci, Maria, T., Appella, E., Schleuning, W-D., Behrendt, N., Ronne, E., Kristensen, P., Pollanen, J., Salonen, E-M., Stephens, Ross, W., Tapiovaara, H., Vaheri, A., Moller Lisbeth, B., Ellis, V., Lund Leif, R., Ploug, M., Pyke, C. & 1 others, Patthy, L., 6 Feb 2003, IPC No. A61K 38/ 00 A N, Patent No. US2003027981, Priority date 8 Jan 2001, Priority No. US20010755109

    Research output: Patent

  71. 2002
  72. Published

    Matriptase/MT-SP1 is required for postnatal survival, epidermal barrier function, hair follicle development, and thymic homeostasis

    List, K., Haudenschild, C. C., Szabo, R., Chen, W., Wahl, S. M., Swaim, W., Engelholm, Lars Henning, Behrendt, Niels & Bugge, T. H., 23 May 2002, In: Oncogene. 21, 23, p. 3765-79 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Urokinase receptor-associated protein (uPARAP) is expressed in connection with malignant as well as benign lesions of the human breast and occurs in specific populations of stromal cells

    Schnack Nielsen, B., Rank, F., Engelholm, Lars Henning, Holm, A., Danø, K. & Behrendt, Niels, 10 Apr 2002, In: International Journal of Cancer. Supplement. 98, 5, p. 656-64 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. 2001
  75. Published

    The urokinase plasminogen activator receptor-associated protein/endo180 is coexpressed with its interaction partners urokinase plasminogen activator receptor and matrix metalloprotease-13 during osteogenesis

    Engelholm, Lars Henning, Nielsen, B. S., Netzel-Arnett, S., Solberg, H., Chen, X. D., Lopez Garcia, J. M., López-Otín, C., Young, M. F., Birkedal-Hansen, H., Danø, K., Lund, L. R., Behrendt, Niels & Bugge, T. H., Oct 2001, In: Laboratory Investigation. 81, 10, p. 1403-14 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Urokinase-catalysed cleavage of the urokinase receptor requires an intact glycolipid anchor

    Høyer-Hansen, G., Pessara, U., Holm, A., Pass, J., Weidle, U., Danø, K. & Behrendt, Niels, 15 Sep 2001, In: Biochemical Journal. 358, Pt 3, p. 673-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Differential binding of urokinase and peptide antagonists to the urokinase receptor: evidence from characterization of the receptor in four primate species

    Engelholm, Lars Henning & Behrendt, Niels, Mar 2001, In: Biological Chemistry. 382, 3, p. 435-42 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    The urokinase receptor associated protein (uPARAP/endo180): a novel internalization receptor connected to the plasminogen activation system

    Engelholm, Lars Henning, Nielsen, B. S., Danø, K. & Behrendt, Niels, Jan 2001, In: Trends in Cardiovascular Medicine. 11, 1, p. 7-13 7 p.

    Research output: Contribution to journalReviewResearchpeer-review

  79. 2000
  80. Plasminogen-independent initiation of the pro-urokinase activation cascade in vivo. Activation of pro-urokinase by glandular kallikrein (mGK-6) in plasminogen-deficient mice

    List, K., Jensen, O. N., Bugge, T. H., Lund, L. R., Ploug, Michael, Danø, K. & Behrendt, Niels, 25 Jan 2000, In: Biochemistry. 39, 3, p. 508-15 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. A urokinase receptor-associated protein with specific collagen binding properties

    Behrendt, Niels, Jensen, O. N., Engelholm, Lars Henning, Mørtz, E., Mann, Matthias & Danø, K., 2000, In: The Journal of Biological Chemistry. 275, 3, p. 1993-2002 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. 1999
  83. Published

    Vectors and methods for recombinant production of uPA-binding fragments of the human urokinase-type plasminogen receptor (uPAR)

    Danoe, K., Blasi, F., Roldan, Ann, L., Cubellis, Maria, V., Masucci, Maria, T., Appella, E., Schleuning, W-D., Behrendt, N., Rønne, E., Kristensen, P., Pollanen, J., Salonen, E-M., Stephens, Ross, W., Tapiovaara, H., Vaheri, A., Moeller, Lisbeth, B., Ellis, V., Lund, Leif, R., Ploug, M., Pyke, C. & 1 others, Patthy, L., 6 Apr 1999, IPC No. A61K 38/ 00 A N, Patent No. US5891664, Priority date 6 Oct 1994, Priority No. US19940319052

    Research output: Patent

  84. Published

    Different mechanisms are involved in the antibody mediated inhibition of ligand binding to the urokinase receptor: a study based on biosensor technology

    List, K., Høyer-Hansen, G., Rønne, Elsebeth, Danø, K. & Behrendt, Niels, 1 Jan 1999, In: Journal of Immunological Methods. 222, 1-2, p. 125-33 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. 1998
  86. Published

    The urokinase receptor

    Behrendt, Niels & Stephens, R. W., 1 Jan 1998, In: Fibrinolysis and Proteolysis. 12, 4, p. 191-204 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  87. 1997
  88. The intact urokinase receptor is required for efficient vitronectin binding: receptor cleavage prevents ligand interaction

    Høyer-Hansen, G., Behrendt, Niels, Ploug, Michael, Danø, K. & Preissner, K. T., 22 Dec 1997, In: FEBS Letters. 420, 1, p. 79-85 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Different mechanisms are involved in the antibody mediated inhibition of the interaction between the urokjnasetype plasminogen activator and its receptor

    List, K., Høyer-Hansen, G., Rønne, E., Danø, K. & Behrendt, Niels, 1 Dec 1997, In: Fibrinolysis and Proteolysis. 11, SUPPL. 3, 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Establishment of murine monoclonal antibodies against murine urokinase receptor raised in urokinase receptor knock-out mice

    Ranne, E., Hansen, G. H., Behrendt, Niels, Solberg, H., Larsen, J. K. & Danø, K., 1 Dec 1997, In: Fibrinolysis and Proteolysis. 11, SUPPL. 3, 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Establishment of murine monoclonal antibodies against murine urokinase receptor raised in urokinase receptor knock-out mice

    Ranne, E., Hansen, G. H., Behrendt, Niels, Solberg, H., Larsen, J. K. & Danø, K., 1 Dec 1997, In: Fibrinolysis and Proteolysis. 11, SUPPL. 3, 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    The rntact urokinase receptor is required for high affinity vitronectin binding: receptor cleavage prevents ligand interaction

    GunillaHaver-Hansjan, Behrendt, Niels, Ploug, Michael, Dana, K. & Preissner, K. T., 1 Dec 1997, In: Fibrinolysis and Proteolysis. 11, SUPPL. 3, 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. ELISA for complexes between urokinase-type plasminogen activator and its receptor in lung cancer tissue extracts

    de Witte, H., Pappot, Helle, Brünner, N., Grøndahl-Hansen, J., Hoyer-Hansen, G., Behrendt, Niels, Guldhammer-Skov, B., Sweep, F., Benraad, T. & Danø, K., 29 Jul 1997, In: International Journal of Cancer. Supplement. 72, 3, p. 416-23 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Reply to comment on 'Effect of purified, soluble urokinase receptor on the plasminogen-prourokinase activation system' (A. A-R. Higazi)

    Behrendt, Niels & Danø, K., 3 Feb 1997, In: FEBS Letters. 402, 2-3, p. 293-4 2 p.

    Research output: Contribution to journalJournal articleResearch

  95. Cell-surface acceleration of urokinase-catalyzed receptor cleavage

    Høyer-Hansen, G., Ploug, Michael, Behrendt, Niels, Rønne, Elsebeth & Danø, K., 15 Jan 1997, In: European Journal of Biochemistry. 243, 1-2, p. 21-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Identification of a novel membrane protein that interacts specifically with the upar-prourokinase complex

    Behrendt, Niels, Engelholm, Lars Henning, Jensen, O. N., Mörtz, E., Ranne, E., Mann, Matthias & Dan, K., 1997, In: Fibrinolysis and Proteolysis. 11, Supl. 3, p. 10 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  97. Structure, function and expression on blood and bone marrow cells of the urokinase-type plasminogen activator receptor, uPAR

    Plesner, T., Behrendt, Niels & Ploug, Michael, 1997, In: Stem Cells. 15, 6, p. 398-408 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  98. 1996
  99. Domain interplay in the urokinase receptor. Requirement for the third domain in high affinity ligand binding and demonstration of ligand contact sites in distinct receptor domains

    Behrendt, Niels, Ronne, E. & Dano, K., 13 Sep 1996, In: The Journal of Biological Chemistry. 271, 37, p. 22885-94 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Effect of purified, soluble urokinase receptor on the plasminogen-prourokinase activation system

    Behrendt, Niels & Danø, K., 9 Sep 1996, In: FEBS Letters. 393, 1, p. 31-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. 1995
  102. The structure and function of the urokinase receptor, a membrane protein governing plasminogen activation on the cell surface

    Behrendt, Niels, Rønne, E. & Danø, K., May 1995, In: Biological Chemistry Hoppe-Seyler. 376, 5, p. 269-79 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  103. 1994
  104. Published

    Quantitation of the receptor for urokinase plasminogen activator by enzyme-linked immunosorbent assay

    Rønne, Elsebeth, Behrendt, Niels, Ploug, Michael, Nielsen, H. J., Wöllisch, E., Weidle, U., Danø, K. & Høyer-Hansen, G., 3 Jan 1994, In: Journal of Immunological Methods. 167, 1-2, p. 91-101 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  105. The urokinase receptor. Protein structure and role in plasminogen activation and cancer invasion

    Danø, K., Behrendt, Niels, Brünner, N., Ellis, V., Ploug, Michael & Oyke, C., 1994, In: Fibrinolysis. 8, Supplement 1, p. 189-203

    Research output: Contribution to journalReviewResearchpeer-review

  106. 1993
  107. A novel, specific pro-urokinase complex on monocyte-like cells, detected by transglutaminase-catalyzed cross-linking

    Behrendt, Niels, Rønne, E. & Danø, K., 28 Dec 1993, In: FEBS Letters. 336, 3, p. 394-6 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  108. Binding of the urokinase-type plasminogen activator to its cell surface receptor is inhibited by low doses of suramin

    Behrendt, Niels, Rønne, E. & Danø, K., 15 Mar 1993, In: The Journal of Biological Chemistry. 268, 8, p. 5985-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  109. Cellular receptor for urokinase-type plasminogen activator: function in cell-surface proteolysis

    Ellis, V., Behrendt, Niels & Danø, K., 1993, Methods in Enzymology. Vol. 223. p. 223-33 11 p. (Methods in Enzymology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  110. Published

    Cellular receptor for urokinase-type plasminogen activator: protein structure

    Behrendt, Niels, Ploug, Michael, Rønne, Elsebeth, Høyer-Hansen, G. & Danø, K., 1993, Methods of Enzymology. Vol. 223. p. 207-22 16 p. (Methods in Enzymology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  111. 1992
  112. Urokinase plasminogen activator cleaves its cell surface receptor releasing the ligand-binding domain

    Høyer-Hansen, G., Rønne, E., Solberg, H., Behrendt, Niels, Ploug, Michael, Lund, L. R., Ellis, V. & Danø, K., 5 Sep 1992, In: The Journal of Biological Chemistry. 267, 25, p. 18224-18229 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  113. Identification and characterization of the murine cell surface receptor for the urokinase-type plasminogen activator

    Solberg, H., Løber, D., Eriksen, J., Ploug, Michael, Rønne, E., Behrendt, Niels, Danø, K. & Høyer-Hansen, G., 15 Apr 1992, In: European Journal of Biochemistry. 205, 2, p. 451-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  114. 1991
  115. Published

    Cell-induced potentiation of the plasminogen activation system is abolished by a monoclonal antibody that recognizes the NH2-terminal domain of the urokinase receptor

    Rønne, Elsebeth, Behrendt, Niels, Ellis, V., Ploug, Michael, Danø, K. & Høyer-Hansen, G., 19 Aug 1991, In: FEBS Letters. 288, 1-2, p. 233-6 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  116. Plasminogen activation by receptor-bound urokinase. A kinetic study with both cell-associated and isolated receptor

    Ellis, V., Behrendt, Niels & Danø, K., 5 Jul 1991, In: The Journal of Biological Chemistry. 266, 19, p. 12752-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  117. Protein structure and membrane anchorage of the cellular receptor for urokinase-type plasminogen activator

    Ploug, Michael, Behrendt, Niels, Løber, D. & Danø, K., Jul 1991, In: Seminars in Thrombosis and Hemostasis. 17, 3, p. 183-93 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  118. Urokinase receptor mRNA level and gene transcription are strongly and rapidly increased by phorbol myristate acetate in human monocyte-like U937 cells

    Lund, L. R., Rønne, E., Roldan, A. L., Behrendt, Niels, Rømer, J., Blasi, F. & Danø, K., 15 Mar 1991, In: The Journal of Biological Chemistry. 266, 8, p. 5177-81 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  119. IDENTIFICATION AND LOCALIZATION OF A SOLUBLE-ANTIGEN, AG2, OF 136-KDA FROM PLASMODIUM-FALCIPARUM INVITRO CULTURES

    Jakobsen, P. H., Grellier, P., THEANDER, T., Behrendt, Niels, Torii, M., Aikawa, M., Schrevel, J. & JEPSEN, S., Feb 1991, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 99, 2, p. 155-162

    Research output: Contribution to journalJournal articleResearchpeer-review

  120. Cellular receptor for urokinase plasminogen activator. Carboxyl-terminal processing and membrane anchoring by glycosyl-phosphatidylinositol

    Ploug, Michael, Rønne, E., Behrendt, Niels, Jensen, A. L., Blasi, F. & Danø, K., 25 Jan 1991, In: The Journal of Biological Chemistry. 266, 3, p. 1926-33 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  121. 1990
  122. Characterization of human endothelial cell urokinase-type plasminogen activator receptor protein and messenger RNA

    Barnathan, E. S., Kuo, A., Kariko, K., Rosenfeld, L., Murray, C. S., Behrendt, Niels, Rønne, Elsebeth, Weiner, D. M., Henkin, J. & Cines, D. B., 1 Nov 1990, In: Blood. 76, 9, p. 1795-806 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  123. Inhibition of receptor-bound urokinase by plasminogen-activator inhibitors

    Ellis, V., Wun, T., Behrendt, Niels, Rønne, Elsebeth & Danø, K., 15 Jun 1990, In: The Journal of Biological Chemistry. 265, 17, p. 9904-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  124. The human receptor for urokinase plasminogen activator. NH2-terminal amino acid sequence and glycosylation variants

    Behrendt, Niels, Rønne, Elsebeth, Ploug, Michael, Petri, T., Løber, D., Nielsen, L. S., Schleuning, W. D., Blasi, F., Appella, E. & Danø, K., 15 Apr 1990, In: The Journal of Biological Chemistry. 265, 11, p. 6453-60 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  125. The urokinase receptor and regulation of cell surface plasminogen activation

    Blasi, F., Cubellis, M. V., Masucci, M. T., Møller, L. B., Olson, D. P., Pedersen, N., Behrendt, Niels, Ellis, V., Ploug, Michael, Rønne, E. & Danø, K., 1990, In: Cell Differentation and Development. 32, 3, p. 247-54

    Research output: Contribution to journalJournal articleResearch

  126. 1989
  127. Activation of pro-urokinase and plasminogen on human sarcoma cells: a proteolytic system with surface-bound reactants

    Stephens, R. W., Pöllänen, J., Tapiovaara, H., Leung, K. C., Sim, P. S., Salonen, E., Rønne, Elsebeth, Behrendt, Niels, Danø, K. & Vaheri, A., May 1989, In: Journal of Cell Biology. 108, 5, p. 1987-95 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  128. Regulation of urokinase receptors in monocytelike U937 cells by phorbol ester phorbol myristate acetate

    Picone, R., Kajtaniak, E. L., Nielsen, L. S., Behrendt, Niels, Mastronicola, M. R., Cubellis, M. V., Stoppelli, M. P., Pedersen, S., Danø, K. & Blasi, F., Feb 1989, In: Journal of Cell Biology. 108, 2, p. 693-702 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  129. 1988
  130. A 55,000-60,000 Mr receptor protein for urokinase-type plasminogen activator. Identification in human tumor cell lines and partial purification

    Nielsen, L. S., Kellerman, G. M., Behrendt, Niels, Picone, R., Danø, K. & Blasi, F., 15 Feb 1988, In: The Journal of Biological Chemistry. 263, 5, p. 2358-63 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  131. 1987
  132. Published

    Localization and functional significance of a polymorphic determinant in the third component of human complement

    Behrendt, Niels, Hansen, Ole, Ploug, Michael, Barkholt, V. & Koch, C., Oct 1987, In: Molecular Immunology. 24, 10, p. 1097-103 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  133. 1986
  134. A novel polymorphism of human complement component C3 detected by means of a monoclonal antibody

    Koch, C. & Behrendt, Niels, 1986, In: Immunogenetics. 23, 5, p. 322-5 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  135. 1985
  136. Human complement component C3: characterization of active C3 S and C3 F, the two common genetic variants

    Behrendt, Niels, Aug 1985, In: Molecular Immunology. 22, 8, p. 1005-8 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 33867134