Ulla M. Wewer

Ulla M. Wewer

Professor


  1. 2018
  2. Published

    Personlig medicin vil involvere alle specialer, og det handler om andet end genomet

    Ullum, H., Hersom, C., Wewer, Ulla M., Skøtt, O., Nielsen, L. B. & Rasmussen, L. H., 2018, In: Ugeskrift for Laeger. 180, 6, p. 501 1 p.

    Research output: Contribution to journalEditorialResearch

  3. 2017
  4. Published

    Corporate culture: research can benefit

    Westendorp, Rudi GJ & Wewer, Ulla M., 2017, In: Nature. 542, 7641, 1 p., 295.

    Research output: Contribution to journalJournal articleCommunication

  5. 2016
  6. Published

    The Phosphorylation and Distribution of Cortactin Downstream of Integrin α9β1 Affects Cancer Cell Behaviour

    Høye, A. M., Couchman, John Robert, Wewer, Ulla M. & Yoneda, A., 2016, In: Scientific Reports. 6, 14 p., 28529.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2013
  8. Published

    ADAM12 redistributes and activates MMP-14, resulting in gelatin degradation, reduced apoptosis and increased tumor growth

    Albrechtsen, Reidar, Kveiborg, Marie, Hansen, D. S., Vikeså, J., Noer, Julie Boertmann, Kotzsh, A., Nielsen, Finn Cilius, Wewer, Ulla M. & Frohlich, C., 15 Oct 2013, In: Journal of Cell Science. 126, 20, p. 4707-20 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    ADAM12

    Kveiborg, Marie, Fröhlich, C., Albrechtsen, Reidar & Wewer, Ulla M., 29 Aug 2013, Handbook of Proteolytic Enzymes. Elsevier, Vol. 1. p. 1114-1122 9 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  10. Published

    ADAM12 is expressed in the tumour vasculature and mediates ectodomain shedding of several membrane-anchored endothelial proteins

    Frohlich, C., Klitgaard, M., Noer, J. B., Kotzsch, A., Nehammer, C., Kronqvist, P., Berthelsen, J., Blobel, C., Kveiborg, Marie, Albrechtsen, Reidar & Wewer, Ulla M., 15 May 2013, In: Biochemical Journal. 452, 1, p. 97-109 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Regulation of ROCK Activity in Cancer

    Morgan-Fisher, M., Wewer, Ulla M. & Yoneda, A., 29 Jan 2013, In: Journal of Histochemistry and Cytochemistry. 61, 3, p. 185-198

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2012
  13. Published

    The newcomer in the integrin family: Integrin α9 in biology and cancer.

    Høye, A. M., Couchman, John Robert, Wewer, Ulla M., Yoneda, A. & Fukami, K., May 2012, In: Advances in Biological Regulation. 52, 2, p. 326-339

    Research output: Contribution to journalReviewResearchpeer-review

  14. Published

    A collapsin response mediator protein 2 isoform controls myosin II-mediated cell migration and matrix assembly by trapping ROCK II

    Yoneda, A., Morgan-Fisher, M., Wait, R., Couchman, John Robert & Wewer, Ulla M., 2012, In: Molecular and Cellular Biology. 32, 10, p. 1788-804 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Cell-surface metalloprotease ADAM12 is internalized by a clathrin- and Grb2-dependent mechanism

    Hansen, D. S., Leyme, A., Grandal, M. V., Albrechtsen, Reidar, van Deurs, B., Wewer, Ulla M. & Kveiborg, Marie, 2012, In: Traffic - International Journal of Intracellular Transport. 13, 11, p. 1532-46 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Functional Analysis of a Breast Cancer-Associated Mutation in the Intracellular Domain of the Metalloprotease ADAM12

    Stautz, D., Wewer, Ulla M. & Kveiborg, Marie, 2012, In: P L o S One. 7, 5, p. e37628

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2011
  18. Published

    ADAM12 produced by tumor cells rather than stromal cells accelerates breast tumor progression

    Frohlich, C., Nehammer, C., Albrechtsen, Reidar, Kronqvist, P., Kveiborg, Marie, Sehara-Fujisawa, A., Mercurio, A. M. & Wewer, Ulla M., 29 Aug 2011, In: Molecular Cancer Research.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Aging, longevity and health

    Rasmussen, Lene Juel, Sander, M., Wewer, Ulla M. & Bohr, Vilhelm, 23 Jul 2011, In: Mechanisms of Ageing and Development. p. 522-32 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    KU bestemmer selv over sin forskning

    Wewer, Ulla M., Holst, Jens Juul, Schwartz, Thue W. & Quistorff, B., 2 Jun 2011, In: Universitetsavisen.

    Research output: Contribution to journalContribution to newspaper - Comment/debateCommunication

  21. Published

    Extracellular engagement of ADAM12 induces clusters of invadopodia with localized ectodomain shedding activity

    Albrechtsen, Reidar, Hansen, D. S., Sanjay, A., Kveiborg, Marie & Wewer, Ulla M., 15 Jan 2011, In: Experimental Cell Research. 317, 2, p. 195-209 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 2010
  23. Published

    ADAM12 localizes with c-Src to actin-rich structures at the cell periphery and regulates Src kinase activity

    Stautz, D., Sanjay, A., Hansen, M. T., Albrechtsen, Reidar, Wewer, Ulla M. & Kveiborg, Marie, 2010, In: Experimental Cell Research. 316, 1, p. 55-67

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Selective inhibition of ADAM12 catalytic activity through engineering of tissue inhibitor of metalloproteinase 2 (TIMP-2)

    Kveiborg, Marie, Jacobsen, J., Lee, M., Nagase, H., Wewer, Ulla M. & Murphy, G., 2010, In: Biochemical Journal. 430, 1, p. 79-86 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. 2009
  26. Published

    Alpha9beta1 integrin in melanoma cells can signal different adhesion states for migration and anchorage

    Lydolph, M. C., Morgan-Fisher, M., Høye, A. M., Couchman, John Robert, Wewer, Ulla M. & Yoneda, A., 2009, In: Experimental Cell Research. 315, 19, p. 3312-24 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Impaired cutaneous wound healing in mice lacking tetranectin

    Iba, K., Hatakeyama, N., Kojima, T., Murata, M., Matsumura, T., Wewer, Ulla M., Wada, T., Sawada, N. & Yamashita, T., 2009, In: Wound Repair and Regeneration. 17, 1, p. 108-12 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Targeting ADAM12 in human disease: head, body or tail?

    Jacobsen, J. & Wewer, Ulla M., 2009, In: Current Pharmaceutical Design. 15, 20, p. 2300-10 10 p.

    Research output: Contribution to journalReviewResearch

  29. 2008
  30. Published

    ADAM12: a potential target for the treatment of chronic wounds

    Harsha, A., Stojadinovic, O., Brem, H., Sehara-Fujisawa, A., Wewer, Ulla M., Loomis, C. A., Blobel, C. P. & Tomic-Canic, M., 1 Aug 2008, In: Journal of Molecular Medicine. 86, 8, p. 961-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Urinary metalloproteinases: noninvasive biomarkers for breast cancer risk assessment

    Pories, S. E., Zurakowski, D., Roy, R., Lamb, C. C., Raza, S., Exarhopoulos, A., Scheib, R. G., Schumer, S., Lenahan, C., Borges, V., Louis, G. W., Anand, A., Isakovich, N., Hirshfield-Bartek, J., Wewer, Ulla M., Lotz, M. M. & Moses, M. A., 1 May 2008, In: Cancer Epidemiology, Biomarkers & Prevention. 17, 5, p. 1034-42 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Aging-From molecules to populations.

    Sander, M., Avlund, K., Lauritzen, Martin, Gottlieb, T., Stevnsner, T., Wewer, Ulla M. & Bohr, V. A., 2008, In: Mechanisms of Ageing and Development. 129, p. 614-623

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Catalytic properties of ADAM12 and its domain deletion mutants.

    Jacobsen, J., Visse, R., Sørensen, H. P., Enghild, J. J., Brew, K., Wewer, Ulla M. & Nagase, H., 2008, In: Biochemistry. 47, 2, p. 537-547 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Cellular roles of ADAM12 in health and disease.

    Kveiborg, Marie, Albrechtsen, Reidar, Couchman, John Robert & Wewer, Ulla M., 2008, In: International Journal of Biochemistry & Cell Biology. 40, 9, p. 1685-702 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Expression, purification and insights into structure and folding of the ADAM22 pro domain.

    Sørensen, H. P., Jacobsen, J., Nielbo, S., Poulsen, F. M. & Wewer, Ulla M., 2008, In: Protein Expression and Purification. 61, 2, p. 175-83 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Heparan sulfate regulates ADAM12 through a molecular switch mechanism.

    Sørensen, H. P., Vives, R. R., Manetopoulos, C., Albrechtsen, Reidar, Lydolph, M. C., Jacobsen, J., Couchman, John Robert & Wewer, Ulla M., 2008, In: Journal of Biological Chemistry.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. 2007
  38. Published

    Transgenic overexpression of ADAM12 suppresses muscle regeneration and aggravates dystrophy in aged mdx mice

    Jørgensen, L. H., Jensen, C. H., Wewer, Ulla M. & Schrøder, H. D., 1 Nov 2007, In: American Journal of Pathology. 171, 5, p. 1599-607 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    ADAM 12 as a second-trimester maternal serum marker in screening for Down syndrome

    Christiansen, M., Spencer, K., Laigaard, J., Cowans, N. J., Larsen, S. O. & Wewer, Ulla M., 2007, In: Prenatal Diagnosis. 27, 7, p. 611-615 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Forsknings- og ytringsfriheden på universiteterne: forskningspolitisk årsmøde 2007

    Kærgård, Niels, Bache, C., Flensted-Jensen, M., Harder, Peter, Olesen, Søren-Peter & Wewer, Ulla M., 2007, København: Det Kongelige Danske Videnskabernes Selskab.

    Research output: Book/ReportBookCommunication

  41. Published

    The disintegrin and metalloproteinase ADAM12 contributes to TGF-beta signaling through interaction with the type II receptor

    Atfi, A., Dumont, E., Colland, F., Bonnier, D., L'helgoualc'h, A., Prunier, C., Ferrand, N., Clément, B., Wewer, Ulla M. & Théret, N., 2007, In: Journal of Cell Biology. 178, 2, p. 201-208 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. 2006
  43. Published

    ADAM 12 as a first-trimester maternal serum marker in screening for Down syndrome

    Laigaard, J., Spencer, K., Christiansen, M., Cowans, N. J., Larsen, S. O., Pedersen, B. N. & Wewer, Ulla M., 2006, In: Prenatal Diagnosis. 26, 10, p. 973-979 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    ADAM12 is a four-leafed clover: the excised prodomain remains bound to the mature enzyme.

    Wewer, Ulla M., Mörgelin, M., Holck, P., Jacobsen, J., Lydolph, M. C., Johnsen, A. H., Kveiborg, Marie & Albrechtsen, Reidar, 2006, In: Journal of Biological Chemistry. 281, 14, p. 9418-22 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    ADAM12-S stimulates bone growth in transgenic mice by modulating chondrocyte proliferation and maturation.

    Kveiborg, Marie, Albrechtsen, Reidar, Rudkjaer, L., Wen, G., Damgaard-Pedersen, K. & Wewer, Ulla M., 2006, In: Journal of Bone and Mineral Research. 21, 8, p. 1288-96 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Maternal serum ADAM12 levels in Down and Edwards' syndrome pregnancies at 9-12 weeks' gestation

    Laigaard, J., Cuckle, H., Wewer, Ulla M. & Christiansen, M., 2006, In: Prenatal Diagnosis. 26, 8, p. 689-691 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Molecular profiling of ADAM12 in human bladder cancer.

    Albrechtsen, Reidar, Dyrskjøt, L., Rudkjaer, L., Ørntoft, T. F., Frohlich, C. & Wewer, Ulla M., 2006, In: Clinical Cancer Research. 12, 24, p. 7359-68 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    RNA-binding IMPs promote cell adhesion and invadopodia formation.

    Vikesaa, J., Hansen, T. V. O., Jønson, L., Borup, R., Wewer, Ulla M., Christiansen, Jan & Nielsen, Finn Cilius, 2006, In: EMBO Journal. 25, 7, p. 1456-68 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. 2005
  50. Published

    Involvement of the serine/threonine p70S6 kinase in TGF-beta1-induced ADAM12 expression in cultured human hepatic stellate cells

    Le Pabic, H., L'Helgoualc'h, A., Coutant, A., Wewer, Ulla M., Baffet, G., Clément, B. & Théret, N., 1 Dec 2005, In: Journal of Hepatology. 43, 6, p. 1038-44 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Sub-cellular localisation of fukutin related protein in different cell lines and in the muscle of patients with MDC1C and LGMD2I

    Torelli, S., Brown, S. C., Brockington, M., Dolatshad, N. F., Jimenez, C., Skordis, L., Feng, L. H., Merlini, L., Jones, D. H., Romero, N., Wewer, Ulla M., Voit, T., Sewry, C. A., Noguchi, S., Nishino, I. & Muntoni, F., 1 Dec 2005, In: Neuromuscular Disorders. 15, 12, p. 836-43 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    ADAM12 overexpression does not improve outcome in mice with laminin alpha2-deficient muscular dystrophy

    Guo, L. T., Shelton, G. D., Wewer, Ulla M. & Engvall, E., 1 Nov 2005, In: Neuromuscular Disorders. 15, 11, p. 786-9 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    PINCH1 regulates cell-matrix and cell-cell adhesions, cell polarity and cell survival during the peri-implantation stage

    Li, S., Bordoy, R., Stanchi, F., Moser, M., Braun, A., Kudlacek, O., Wewer, Ulla M., Yurchenco, P. D. & Fässler, R., 1 Jul 2005, In: Journal of Cell Science. 118, Pt 13, p. 2913-21 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    ADAM12 and alpha9beta1 integrin are instrumental in human myogenic cell differentiation

    Lafuste, P., Sonnet, C., Chazaud, B., Dreyfus, P. A., Gherardi, R. K., Wewer, Ulla M. & Authier, F., 1 Feb 2005, In: Molecular Biology of the Cell. 16, 2, p. 861-70 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    A role for ADAM12 in breast tumor progression and stromal cell apoptosis.

    Kveiborg, Marie, Frohlich, C., Albrechtsen, Reidar, Tischler, V., Dietrich, N., Holck, P., Kronqvist, P., Rank, F., Mercurio, A. M. & Wewer, Ulla M., 2005, In: Cancer Research. 65, 11, p. 4754-61 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    ADAM12-mediated focal adhesion formation is differently regulated by beta1 and beta3 integrins.

    Thodeti, C. K., Frohlich, C., Nielsen, C. K., Takada, Y., Fässler, R., Albrechtsen, Reidar & Wewer, Ulla M., 2005, In: FEBS Letters. 579, 25, p. 5589-95 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Expression of IGF-II mRNA-binding proteins (IMPs) in gonads and testicular cancer

    Hammer, N. A., Hansen, Thomas van Overeem, Byskov, A. G., Rajpert-De Meyts, E., Grøndahl, M. L., Bredkjaer, H. E., Wewer, Ulla M., Christiansen, Jan & Nielsen, Finn Cilius, 2005, In: Reproduction. 130, 2, p. 203-12 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Hierarchy of ADAM12 binding to integrins in tumor cells.

    Thodeti, C. K., Fröhlich, C., Nielsen, C. K., Holck, P., Sundberg, C., Kveiborg, Marie, Mahalingam, Y., Albrechtsen, Reidar, Couchman, John Robert & Wewer, Ulla M., 2005, In: Experimental Cell Research. 309, 2, p. 438-50 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Reduction of the disintegrin and metalloprotease ADAM12 in preeclampsia.

    Laigaard, J., Sørensen, T., Placing, S., Holck, P., Frohlich, C., Wøjdemann, K. R., Sundberg, K., Shalmi, A., Tabor, A., Nørgaard-Pedersen, B., Ottesen, B., Christiansen, M. & Wewer, Ulla M., 2005, In: Obstetrics and Gynecology. 106, 1, p. 144-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    The level of ADAM12-S in maternal serum is an early first-trimester marker of fetal trisomy 18.

    Laigaard, J., Christiansen, M., Frohlich, C., Pedersen, B. N., Ottesen, B. & Wewer, Ulla M., 2005, In: Prenatal Diagnosis. 25, 1, p. 45-6 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. 2004
  62. Published

    ADAM 12 cleaves extracellular matrix proteins and correlates with cancer status and stage

    Roy, R., Wewer, Ulla M., Zurakowski, D., Pories, S. E. & Moses, M. A., 3 Dec 2004, In: Journal of Biological Chemistry. 279, 49, p. 51323-30 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Dwarfism and impaired gut development in insulin-like growth factor II mRNA-binding protein 1-deficient mice

    Hansen, Thomas van Overeem, Hammer, N. A., Nielsen, J., Madsen, Mette, Dalbaeck, C., Wewer, Ulla M., Christiansen, Jan & Nielsen, Finn Cilius, 2004, In: Molecular and Cellular Biology. 24, 10, p. 4448-64 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Moses MA. ADAM 12 cleaves ECM proteins: Correlation with cancer status and stage

    Roy, R., Wewer, Ulla M., Zurakowski, D., Pories, S. E. & Moses, M. A., 2004, In: Journal of Biological Chemistry. 279, p. 51323-51330

    Research output: Contribution to journalJournal articleResearch

  65. Published

    Regulation of ADAM12 cell-surface expression by protein kinase C epsilon.

    Sundberg, C., Thodeti, C. K., Kveiborg, Marie, Larsson, C., Parker, P., Albrechtsen, Reidar & Wewer, Ulla M., 2004, In: Journal of Biological Chemistry. 279, 49, p. 51601-11 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. 2003
  67. Published

    Compensation for dystrophin-deficiency: ADAM12 overexpression in skeletal muscle results in increased alpha 7 integrin, utrophin and associated glycoproteins

    Moghadaszadeh, B., Albrechtsen, Reidar, Guo, L. T., Zaik, M., Kawaguchi, N., Borup, R. H., Kronqvist, P., Schroder, H. D., Davies, K. E., Voit, T., Nielsen, Finn Cilius, Engvall, E. & Wewer, Ulla M., 1 Oct 2003, In: Human Molecular Genetics. 12, 19, p. 2467-79 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    114th ENMC International Workshop on Congenital Muscular Dystrophy (CMD) 17-19 January 2003, Naarden, The Netherlands: (8th Workshop of the International Consortium on CMD; 3rd Workshop of the MYO-CLUSTER project GENRE)

    Muntoni, F., Valero de Bernabe, B., Bittner, R., Blake, D., van Bokhoven, H., Brockington, M., Brown, S., Bushby, K., Campbell, K. P., Fiszman, M., Gruenewald, S., Merlini, L., Quijano-Roy, S., Romero, N., Sabatelli, P., Sewry, C. A., Straub, V., Talim, B., Topaloglu, H., Voit, T. & 4 others, Yurchenco, P. D., Urtizberea, J. A., Wewer, Ulla M. & Guicheney, P., 1 Sep 2003, In: Neuromuscular Disorders. 13, 7-8, p. 579-88 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    The new frontier in muscular dystrophy research: booster genes

    Engvall, E. & Wewer, Ulla M., 1 Sep 2003, In: F A S E B Journal. 17, 12, p. 1579-84 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    ADAM12 in human liver cancers: TGF-beta-regulated expression in stellate cells is associated with matrix remodeling

    Le Pabic, H., Bonnier, D., Wewer, Ulla M., Coutand, A., Musso, O., Baffet, G., Clément, B. & Théret, N., 1 May 2003, In: Hepatology. 37, 5, p. 1056-66 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Selenoprotein N: an endoplasmic reticulum glycoprotein with an early developmental expression pattern

    Petit, N., Lescure, A., Rederstorff, M., Krol, A., Moghadaszadeh, B., Wewer, Ulla M. & Guicheney, P., 1 May 2003, In: Human Molecular Genetics. 12, 9, p. 1045-53 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Laminin alpha2 deficiency and muscular dystrophy; genotype-phenotype correlation in mutant mice

    Guo, L. T., Zhang, X. U., Kuang, W., Xu, H., Liu, L. A., Vilquin, J., Miyagoe-Suzuki, Y., Takeda, S., Ruegg, M. A., Wewer, Ulla M. & Engvall, E., 1 Mar 2003, In: Neuromuscular Disorders. 13, 3, p. 207-15 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    ADAM12 induces actin cytoskeleton and extracellular matrix reorganization during early adipocyte differentiation by regulating beta1 integrin function.

    Kawaguchi, N., Sundberg, C., Kveiborg, Marie, Moghadaszadeh, B., Asmar, M., Dietrich, N., Thodeti, C. K., Nielsen, F. C., Möller, P., Mercurio, A. M., Albrechtsen, Reidar & Wewer, Ulla M., 2003, In: Journal of Cell Science. 116, Pt 19, p. 3893-904 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    ADAM12: a novel first-trimester maternal serum marker for Down syndrome.

    Laigaard, J., Sørensen, T., Fröhlich, C., Pedersen, B. N., Christiansen, M., Schiøtt, K., Uldbjerg, N., Albrechtsen, Reidar, Clausen, H. V., Ottesen, B. & Wewer, Ulla M., 2003, In: Prenatal Diagnosis. 23, 13, p. 1086-91 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    An endoplasmic reticulum glycoprotein with an early development expression pattern.

    Petit, N., Lescure, A., Rederstorff, M., Krol, A., Moghadas Zadeh, S. B., Wewer, Ulla M. & Guicheney, P., 2003, In: Human Molecular Genetics. 12, p. 1045-1053

    Research output: Contribution to journalJournal articleResearch

  76. Published

    Compensation for dystrophin-deficiency: ADAM12 overexpression in skeletal muscle results in increased alfa7 integrin, utrophin, and associated glycoproteins.

    Moghadas Zadeh, S. B., Albrechtsen, Reidar, Guo, L. T., Zaik, M., Kawaguchi, N., Borup, R. H., Kronqvist, P. E., Schröder, H. D., Davies, K. E., Voit, T., Nielsen, F. C., Engvall, E. & Wewer, Ulla M., 2003, In: Human Molecular Genetics. 12, p. 2467-2479

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Laminin afra2 deficiency and muscular dystrophy: genotype-phenotype correlation in mutant mice.

    Guo, L. T., Zhang, X. U., Kang, W., Xu, H., Liu, L. A., Miyagoe-Suzuki, Y., Takeda, S., Ruegg, M., Wewer, Ulla M. & Engvall, E., 2003, In: Neuromuscular Disorders. 13, p. 207-215

    Research output: Contribution to journalJournal articleResearch

  78. Published

    The new frontier in muscular dystrophy: Booster genes.

    Engvall, E. & Wewer, Ulla M., 2003, In: The FASEB Journal. 17, p. 1579-1584

    Research output: Contribution to journalJournal articleResearch

  79. 2002
  80. Published

    98th ENMC International Workshop on Congenital Muscular Dystrophy (CMD), 7th Workshop of the International Consortium on CMD, 2nd Workshop of the MYO CLUSTER project GENRE. 26-28th October, 2001, Naarden, The Netherlands

    Muntoni, F., Bertini, E., Bönnemann, C., Brockington, M., Brown, S., Bushby, K., Fiszman, M., Körner, C., Mercuri, E., Merlini, L., Hewitt, J., Quijano-Roy, S., Romero, N., Squarzoni, S., Sewry, C. A., Straub, V., Topaloglu, H., Haliloglu, G., Voit, T., Wewer, U. & 1 others, Guicheney, P., 1 Nov 2002, In: Neuromuscular Disorders. 12, 9, p. 889-96 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    ADAM12 alleviates the skeletal muscle pathology in mdx dystrophic mice

    Kronqvist, P., Kawaguchi, N., Albrechtsen, Reidar, Xu, X., Schrøder, H. D., Moghadaszadeh, B., Nielsen, Finn Cilius, Frohlich, C., Engvall, E. & Wewer, Ulla M., 1 Nov 2002, In: American Journal of Pathology. 161, 5, p. 1535-40 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    98th ENMC International Workshop on congenital Muscular Dystrophy (CMD)

    Muntoni, F., Bertine, E., Bonnemann, C., Brockington, M., Bushby, K., Fiszman, M., Korner, C., Mercuri, E., Merlini, L., Hewitt, J., Quijano-Roy, S., Romero, N., Squarzoni, S., Sewry, C. A., Straub, V., Hopaloglu, H., Haliloglu, G., Voit, T., Wewer, Ulla M. & Guicheney, P., 2002, In: Neuromuscular Disorders. 12, p. 889-896

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    ADAM 12 alleviates the skeletal muscle 0pathology in mdx dystrophic mice

    Kronqvist, P. E., Kawaguchi, N., Albrechtsen, Reidar, Xu, X., Schrøder, H. D., Moghadas Zadeh, S. B., Nielsen, F. C., Frohlich, L. C., Engvall, E. & Wewer, Ulla M., 2002, In: American Journal of Pathology. 161, p. 1535-1540

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    ADAM 12 protease induces adipogenesis in transgenic mice.

    Kawaguchi, N., Xu, X., Tajima, R., Kronqvist, P., Sundberg, C., Loechel, F., Albrechtsen, Reidar & Wewer, Ulla M., 2002, In: American Journal of Pathology. 160, 5, p. 1895-903 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    ADAM12/syndecan-4 signaling promotes beta 1 integrin-dependent cell spreading through protein kinase Calpha and RhoA.

    Thodeti, C. K., Albrechtsen, Reidar, Grauslund, M., Asmar, M., Larsson, C., Takada, Y., Mercurio, A. M., Couchman, John Robert & Wewer, Ulla M., 2002, In: Journal of Biological Chemistry. 278, 11, p. 9576-84 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Tetranectin

    Wewer, Ulla M. & Albrechtsen, Reidar, 2002, In: Wiley Encyclopedia of Molecular Medicine. 5, p. 3117-3118

    Research output: Contribution to journalJournal articleResearch

  87. 2001
  88. Published

    Activation of ADAM 12 protease by copper

    Loechel, F. & Wewer, Ulla M., 2001, In: FEBS Letters. 506, 1, p. 65-68 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    E2F repression by C/EBPalpha is required for adipogenesis and granulopoiesis in vivo.

    Porse, Bo Torben, Pedersen TA, Xu, X., Lindberg, B., Wewer, Ulla M., Friis-Hansen, L. & Nerlov, C., 2001, In: Cell. 107, 2, p. 247-58 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Mice with a targeted deletion of the tetranectin gene exhibit a spinal deformity.

    Iba, K., Durkin, M. E., Johnsen, L., Hunziker, E., Damgaard-Pedersen, K., Zhang, H., Engvall, E., Albrechtsen, Reidar & Wewer, Ulla M., 2001, In: Molecular and Cellular Biology. 21, 22, p. 7817-25 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Regulation of laminin beta2 chain gene expression in human cancer cell lines.

    Durkin, M. E., Nielsen, F. C., Loechel, F., Albrechtsen, Reidar & Wewer, Ulla M., 2001, In: European Journal of Biochemistry. 268, 13, p. 3797-806 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Tetranectin in slow intra- and extrafusal chicken muscle fibers.

    Xu, X., Gilpin, B., Iba, K., Maier, A., Engvall, E., Albrechtsen, Reidar & Wewer, Ulla M., 2001, In: Journal of Muscle Research and Cell Motility. 22, 2, p. 121-32 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. 2000
  94. Published

    Binding of ADAM12, a marker of skeletal muscle regeneration, to the muscle-specific actin-binding protein, alpha -actinin-2, is required for myoblast fusion

    Galliano, M. F., Huet, C., Frygelius, J., Polgren, A., Wewer, Ulla M. & Engvall, E., 5 May 2000, In: Journal of Biological Chemistry. 275, 18, p. 13933-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    ADAM 12, a disintegrin metalloprotease, interacts with insulin-like growth factor-binding protein-3

    Shi, Z., Xu, W., Loechel, F., Wewer, Ulla M. & Murphy, L., 2000, In: Journal of Biological Chemistry. 275, 24, p. 18574-18580

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    ADAM 12-S cleaves IGFBP-3 and IGFBP-5 and is inhibited by TIMP-3.

    Loechel, F., Fox, J. W., Murphy, G., Albrechtsen, Reidar & Wewer, Ulla M., 2000, In: Biochemical and Biophysical Research Communications. 278, 3, p. 511-5 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Binding of ADAM12, a marker for skeletal muscle regeneration, to the muscle-specific actin-binding protein, alfa-actinin-2, is required for myoblast fusion.

    Galliano, H., Frygelius, J., Polgren, A. & Wewer, Ulla M., 2000, In: Journal of Biological Chemistry. 275, p. 13933-13999

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Celle-matrix-interaktioner ved cancer

    Wewer, Ulla M., 2000, In: Ugeskrift for læger. 162, 36, p. 4783-5 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    H19 RNA binds four molecules of insulin-like growth factor II mRNA-binding protein

    Runge, S., Nielsen, Finn Cilius, Nielsen, J., Andersen, J. L., Wewer, Ulla M. & Christiansen, Jan, 2000, In: Journal of Biological Chemistry. 275, 38, p. 29562-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    The cysteine-rich domain of human ADAM 12 supports cell adhesion through syndecans and triggers signaling events that lead to beta1 integrin-dependent cell spreading.

    Iba, K., Albrechtsen, Reidar, Gilpin, B., Frohlich, C., Loechel, F., Zolkiewska, A., Ishiguro, K., Kojima, T., Liu, W., Langford, J. K., Sanderson, R. D., Brakebusch, Cord Herbert, Fässler, R. & Wewer, Ulla M., 2000, In: Journal of Cell Biology. 149, 5, p. 1143-56 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    Trafficking of human ADAM 12-L: retention in the trans-Golgi network.

    Hougaard, S., Loechel, F., Xu, X., Tajima, R., Albrechtsen, Reidar & Wewer, Ulla M., 2000, In: Biochemical and Biophysical Research Communications. 275, 2, p. 261-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  102. 1999
  103. Published

    A family of insulin-like growth factor II mRNA-binding proteins represses translation in late development

    Nielsen, J., Christiansen, Jan, Lykke-Andersen, J., Johnsen, A. H., Wewer, Ulla M. & Nielsen, Finn Cilius, 1999, In: Molecular and Cellular Biology. 19, 2, p. 1262-1270 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  104. Published

    Characterization of the human laminin beta2 chain locus (LAMB2): linkage to a gene containing a nonprocessed, transcribed LAMB2-like pseudogene (LAMB2L) and to the gene encoding glutaminyl tRNA synthetase (QARS).

    Durkin, M. E., Jäger, A. C., Khurana, T. S., Nielsen, F. C., Albrechtsen, Reidar & Wewer, Ulla M., 1999, In: Cytogenetic and Genome Research. 84, 3-4, p. 173-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  105. Published

    Cysteine-rich domain of human ADAM 12 (meltrin alpha) supports tumor cell adhesion.

    Iba, K., Albrechtsen, Reidar, Gilpin, B. J., Loechel, F. & Wewer, Ulla M., 1999, In: American Journal of Pathology. 154, 5, p. 1489-501 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  106. Published

    Regulation of human ADAM 12 protease by the prodomain. Evidence for a functional cysteine switch.

    Loechel, F., Overgaard, M. T., Oxvig, C., Albrechtsen, Reidar & Wewer, Ulla M., 1999, In: Journal of Biological Chemistry. 274, 19, p. 13427-33 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  107. 1998
  108. Published

    Laminin alpha2 chain-deficient congenital muscular dystrophy: variable epitope expression in severe and mild cases

    Cohn, R. D., Herrmann, R., Sorokin, L., Wewer, Ulla M. & Voit, T., 1 Jul 1998, In: Neurology. 51, 1, p. 94-100 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  109. Published

    Congenital myasthenic syndromes in two kinships with end-plate acetylcholine receptor and utrophin deficiency

    Sieb, J. P., Dörfler, P., Tzartos, S., Wewer, Ulla M., Rüegg, M. A., Meyer, D., Baumann, I., Lindemuth, R., Jakschik, J. & Ries, F., 1 Jan 1998, In: Neurology. 50, 1, p. 54-61 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  110. Published

    A novel, secreted form of human ADAM 12 (meltrin alpha) provokes myogenesis in vivo.

    Gilpin, B. J., Loechel, F., Mattei, M. G., Engvall, E., Albrechtsen, Reidar & Wewer, Ulla M., 1998, In: Journal of Biological Chemistry. 273, 1, p. 157-66 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  111. Published

    Congenital myastenic syndromes in two kinships with endplate acetylcholine receptor and utropin deficiency

    Sieb, J. P., Dörfler, P., Tzartos, S., Wewer, Ulla M., Rüegg, M. A., Meyer, D., Baumann, I. & Lindemuth, R., 1998, In: Neurology. 50, p. 54-61

    Research output: Contribution to journalJournal articleResearchpeer-review

  112. Published

    Evaluation of Lama5 as a candidate for the mouse ragged (Ra) mutation.

    Durkin, M. E., Albrechtsen, Reidar, Chambers, D. M., Abbott, C. M. & Wewer, Ulla M., 1998, In: Biochemical and Biophysical Research Communications. 250, 1, p. 125-30 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  113. Published

    Genetic correction of merosin deficiency in the dy2J mouse model of congenital muscular dystrophy. Partial genetic correction in two models

    Kuang, W., Xu, H., Vachon, P. H., Liu, L., Loechel, F., Wewer, Ulla M. & Engvall, E., 1998, In: Journal of Clinical Investigation. 102, p. 844-852

    Research output: Contribution to journalJournal articleResearchpeer-review

  114. Published

    Human ADAM 12 (meltrin alpha) is an active metalloprotease.

    Loechel, F., Gilpin, B. J., Engvall, E., Albrechtsen, Reidar & Wewer, Ulla M., 1998, In: Journal of Biological Chemistry. 273, 27, p. 16993-7 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  115. Published

    Laminin alpha2 chain-deficient muscular dystrophy: variable epitope expression in severe and mild cases

    Cohn, R. D., Herrmann, R. J., Sorokin, L., Wewer, Ulla M. & Voit, T., 1998, In: Neurology. 51, p. 94-100

    Research output: Contribution to journalJournal articleResearchpeer-review

  116. Published

    Merosin-deficient congenital muscular dystrophy. Partial genetic correction in two mouse models

    Kuang, W., Xu, H., Vachon, P. H., Liu, L., Loechel, F., Wewer, Ulla M. & Engvall, E., 1998, In: Journal of Clinical Investigation. 102, 4, p. 844-52 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  117. Published

    Tetranectin is a novel marker for myogenesis during embryonic development, muscle regeneration, and muscle cell differentiation in vitro.

    Wewer, Ulla M., Iba, K., Durkin, M. E., Nielsen, F. C., Loechel, F., Gilpin, B. J., Kuang, W., Engvall, E. & Albrechtsen, Reidar, 1998, In: Developmental Biology. 200, 2, p. 247-59 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  118. 1997
  119. Published

    Integrins (alpha7beta1) in muscle function and survival. Disrupted expression in merosin-deficient congenital muscular dystrophy

    Vachon, P. H., Xu, H., Liu, L., Loechel, F., Hayashi, Y., Arahata, K., Reed, J. C., Wewer, Ulla M. & Engvall, E., 1 Oct 1997, In: Journal of Clinical Investigation. 100, 7, p. 1870-81 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  120. Published

    Changes of laminin beta 2 chain expression in congenital muscular dystrophy

    Cohn, R. D., Herrmann, R., Wewer, Ulla M. & Voit, T., 1 Sep 1997, In: Neuromuscular Disorders. 7, 6-7, p. 373-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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