Ulla M. Wewer
Professor
Globe Administration
Øster Voldgade 5-7
1350 København K
- 2018
- Published
Personlig medicin vil involvere alle specialer, og det handler om andet end genomet
Ullum, H., Hersom, C., Wewer, Ulla M., Skøtt, O., Nielsen, L. B. & Rasmussen, L. H., 2018, In: Ugeskrift for Laeger. 180, 6, p. 501 1 p.Research output: Contribution to journal › Editorial › Research
- 2017
- Published
Corporate culture: research can benefit
Westendorp, Rudi GJ & Wewer, Ulla M., 2017, In: Nature. 542, 7641, 1 p., 295.Research output: Contribution to journal › Journal article › Communication
- 2016
- Published
The Phosphorylation and Distribution of Cortactin Downstream of Integrin α9β1 Affects Cancer Cell Behaviour
Høye, A. M., Couchman, John Robert, Wewer, Ulla M. & Yoneda, A., 2016, In: Scientific Reports. 6, 14 p., 28529.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
ADAM12 redistributes and activates MMP-14, resulting in gelatin degradation, reduced apoptosis and increased tumor growth
Albrechtsen, Reidar, Kveiborg, Marie, Hansen, D. S., Vikeså, J., Noer, Julie Boertmann, Kotzsh, A., Nielsen, Finn Cilius, Wewer, Ulla M. & Frohlich, C., 15 Oct 2013, In: Journal of Cell Science. 126, 20, p. 4707-20 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADAM12
Kveiborg, Marie, Fröhlich, C., Albrechtsen, Reidar & Wewer, Ulla M., 29 Aug 2013, Handbook of Proteolytic Enzymes. Elsevier, Vol. 1. p. 1114-1122 9 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
ADAM12 is expressed in the tumour vasculature and mediates ectodomain shedding of several membrane-anchored endothelial proteins
Frohlich, C., Klitgaard, M., Noer, J. B., Kotzsch, A., Nehammer, C., Kronqvist, P., Berthelsen, J., Blobel, C., Kveiborg, Marie, Albrechtsen, Reidar & Wewer, Ulla M., 15 May 2013, In: Biochemical Journal. 452, 1, p. 97-109 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of ROCK Activity in Cancer
Morgan-Fisher, M., Wewer, Ulla M. & Yoneda, A., 29 Jan 2013, In: Journal of Histochemistry and Cytochemistry. 61, 3, p. 185-198Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
The newcomer in the integrin family: Integrin α9 in biology and cancer.
Høye, A. M., Couchman, John Robert, Wewer, Ulla M., Yoneda, A. & Fukami, K., May 2012, In: Advances in Biological Regulation. 52, 2, p. 326-339Research output: Contribution to journal › Review › Research › peer-review
- Published
A collapsin response mediator protein 2 isoform controls myosin II-mediated cell migration and matrix assembly by trapping ROCK II
Yoneda, A., Morgan-Fisher, M., Wait, R., Couchman, John Robert & Wewer, Ulla M., 2012, In: Molecular and Cellular Biology. 32, 10, p. 1788-804 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cell-surface metalloprotease ADAM12 is internalized by a clathrin- and Grb2-dependent mechanism
Hansen, D. S., Leyme, A., Grandal, M. V., Albrechtsen, Reidar, van Deurs, B., Wewer, Ulla M. & Kveiborg, Marie, 2012, In: Traffic - International Journal of Intracellular Transport. 13, 11, p. 1532-46 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional Analysis of a Breast Cancer-Associated Mutation in the Intracellular Domain of the Metalloprotease ADAM12
Stautz, D., Wewer, Ulla M. & Kveiborg, Marie, 2012, In: P L o S One. 7, 5, p. e37628Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
ADAM12 produced by tumor cells rather than stromal cells accelerates breast tumor progression
Frohlich, C., Nehammer, C., Albrechtsen, Reidar, Kronqvist, P., Kveiborg, Marie, Sehara-Fujisawa, A., Mercurio, A. M. & Wewer, Ulla M., 29 Aug 2011, In: Molecular Cancer Research.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aging, longevity and health
Rasmussen, Lene Juel, Sander, M., Wewer, Ulla M. & Bohr, Vilhelm, 23 Jul 2011, In: Mechanisms of Ageing and Development. p. 522-32 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
KU bestemmer selv over sin forskning
Wewer, Ulla M., Holst, Jens Juul, Schwartz, Thue W. & Quistorff, B., 2 Jun 2011, In: Universitetsavisen.Research output: Contribution to journal › Contribution to newspaper - Comment/debate › Communication
- Published
Extracellular engagement of ADAM12 induces clusters of invadopodia with localized ectodomain shedding activity
Albrechtsen, Reidar, Hansen, D. S., Sanjay, A., Kveiborg, Marie & Wewer, Ulla M., 15 Jan 2011, In: Experimental Cell Research. 317, 2, p. 195-209 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
ADAM12 localizes with c-Src to actin-rich structures at the cell periphery and regulates Src kinase activity
Stautz, D., Sanjay, A., Hansen, M. T., Albrechtsen, Reidar, Wewer, Ulla M. & Kveiborg, Marie, 2010, In: Experimental Cell Research. 316, 1, p. 55-67Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selective inhibition of ADAM12 catalytic activity through engineering of tissue inhibitor of metalloproteinase 2 (TIMP-2)
Kveiborg, Marie, Jacobsen, J., Lee, M., Nagase, H., Wewer, Ulla M. & Murphy, G., 2010, In: Biochemical Journal. 430, 1, p. 79-86 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Alpha9beta1 integrin in melanoma cells can signal different adhesion states for migration and anchorage
Lydolph, M. C., Morgan-Fisher, M., Høye, A. M., Couchman, John Robert, Wewer, Ulla M. & Yoneda, A., 2009, In: Experimental Cell Research. 315, 19, p. 3312-24 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired cutaneous wound healing in mice lacking tetranectin
Iba, K., Hatakeyama, N., Kojima, T., Murata, M., Matsumura, T., Wewer, Ulla M., Wada, T., Sawada, N. & Yamashita, T., 2009, In: Wound Repair and Regeneration. 17, 1, p. 108-12 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeting ADAM12 in human disease: head, body or tail?
Jacobsen, J. & Wewer, Ulla M., 2009, In: Current Pharmaceutical Design. 15, 20, p. 2300-10 10 p.Research output: Contribution to journal › Review › Research
- 2008
- Published
ADAM12: a potential target for the treatment of chronic wounds
Harsha, A., Stojadinovic, O., Brem, H., Sehara-Fujisawa, A., Wewer, Ulla M., Loomis, C. A., Blobel, C. P. & Tomic-Canic, M., 1 Aug 2008, In: Journal of Molecular Medicine. 86, 8, p. 961-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Urinary metalloproteinases: noninvasive biomarkers for breast cancer risk assessment
Pories, S. E., Zurakowski, D., Roy, R., Lamb, C. C., Raza, S., Exarhopoulos, A., Scheib, R. G., Schumer, S., Lenahan, C., Borges, V., Louis, G. W., Anand, A., Isakovich, N., Hirshfield-Bartek, J., Wewer, Ulla M., Lotz, M. M. & Moses, M. A., 1 May 2008, In: Cancer Epidemiology, Biomarkers & Prevention. 17, 5, p. 1034-42 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aging-From molecules to populations.
Sander, M., Avlund, K., Lauritzen, Martin, Gottlieb, T., Stevnsner, T., Wewer, Ulla M. & Bohr, V. A., 2008, In: Mechanisms of Ageing and Development. 129, p. 614-623Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Catalytic properties of ADAM12 and its domain deletion mutants.
Jacobsen, J., Visse, R., Sørensen, H. P., Enghild, J. J., Brew, K., Wewer, Ulla M. & Nagase, H., 2008, In: Biochemistry. 47, 2, p. 537-547 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cellular roles of ADAM12 in health and disease.
Kveiborg, Marie, Albrechtsen, Reidar, Couchman, John Robert & Wewer, Ulla M., 2008, In: International Journal of Biochemistry & Cell Biology. 40, 9, p. 1685-702 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression, purification and insights into structure and folding of the ADAM22 pro domain.
Sørensen, H. P., Jacobsen, J., Nielbo, S., Poulsen, F. M. & Wewer, Ulla M., 2008, In: Protein Expression and Purification. 61, 2, p. 175-83 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heparan sulfate regulates ADAM12 through a molecular switch mechanism.
Sørensen, H. P., Vives, R. R., Manetopoulos, C., Albrechtsen, Reidar, Lydolph, M. C., Jacobsen, J., Couchman, John Robert & Wewer, Ulla M., 2008, In: Journal of Biological Chemistry.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
Transgenic overexpression of ADAM12 suppresses muscle regeneration and aggravates dystrophy in aged mdx mice
Jørgensen, L. H., Jensen, C. H., Wewer, Ulla M. & Schrøder, H. D., 1 Nov 2007, In: American Journal of Pathology. 171, 5, p. 1599-607 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADAM 12 as a second-trimester maternal serum marker in screening for Down syndrome
Christiansen, M., Spencer, K., Laigaard, J., Cowans, N. J., Larsen, S. O. & Wewer, Ulla M., 2007, In: Prenatal Diagnosis. 27, 7, p. 611-615 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Forsknings- og ytringsfriheden på universiteterne: forskningspolitisk årsmøde 2007
Kærgård, Niels, Bache, C., Flensted-Jensen, M., Harder, Peter, Olesen, Søren-Peter & Wewer, Ulla M., 2007, København: Det Kongelige Danske Videnskabernes Selskab.Research output: Book/Report › Book › Communication
- Published
The disintegrin and metalloproteinase ADAM12 contributes to TGF-beta signaling through interaction with the type II receptor
Atfi, A., Dumont, E., Colland, F., Bonnier, D., L'helgoualc'h, A., Prunier, C., Ferrand, N., Clément, B., Wewer, Ulla M. & Théret, N., 2007, In: Journal of Cell Biology. 178, 2, p. 201-208 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
ADAM 12 as a first-trimester maternal serum marker in screening for Down syndrome
Laigaard, J., Spencer, K., Christiansen, M., Cowans, N. J., Larsen, S. O., Pedersen, B. N. & Wewer, Ulla M., 2006, In: Prenatal Diagnosis. 26, 10, p. 973-979 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADAM12 is a four-leafed clover: the excised prodomain remains bound to the mature enzyme.
Wewer, Ulla M., Mörgelin, M., Holck, P., Jacobsen, J., Lydolph, M. C., Johnsen, A. H., Kveiborg, Marie & Albrechtsen, Reidar, 2006, In: Journal of Biological Chemistry. 281, 14, p. 9418-22 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADAM12-S stimulates bone growth in transgenic mice by modulating chondrocyte proliferation and maturation.
Kveiborg, Marie, Albrechtsen, Reidar, Rudkjaer, L., Wen, G., Damgaard-Pedersen, K. & Wewer, Ulla M., 2006, In: Journal of Bone and Mineral Research. 21, 8, p. 1288-96 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maternal serum ADAM12 levels in Down and Edwards' syndrome pregnancies at 9-12 weeks' gestation
Laigaard, J., Cuckle, H., Wewer, Ulla M. & Christiansen, M., 2006, In: Prenatal Diagnosis. 26, 8, p. 689-691 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular profiling of ADAM12 in human bladder cancer.
Albrechtsen, Reidar, Dyrskjøt, L., Rudkjaer, L., Ørntoft, T. F., Frohlich, C. & Wewer, Ulla M., 2006, In: Clinical Cancer Research. 12, 24, p. 7359-68 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RNA-binding IMPs promote cell adhesion and invadopodia formation.
Vikesaa, J., Hansen, T. V. O., Jønson, L., Borup, R., Wewer, Ulla M., Christiansen, Jan & Nielsen, Finn Cilius, 2006, In: EMBO Journal. 25, 7, p. 1456-68 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Involvement of the serine/threonine p70S6 kinase in TGF-beta1-induced ADAM12 expression in cultured human hepatic stellate cells
Le Pabic, H., L'Helgoualc'h, A., Coutant, A., Wewer, Ulla M., Baffet, G., Clément, B. & Théret, N., 1 Dec 2005, In: Journal of Hepatology. 43, 6, p. 1038-44 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sub-cellular localisation of fukutin related protein in different cell lines and in the muscle of patients with MDC1C and LGMD2I
Torelli, S., Brown, S. C., Brockington, M., Dolatshad, N. F., Jimenez, C., Skordis, L., Feng, L. H., Merlini, L., Jones, D. H., Romero, N., Wewer, Ulla M., Voit, T., Sewry, C. A., Noguchi, S., Nishino, I. & Muntoni, F., 1 Dec 2005, In: Neuromuscular Disorders. 15, 12, p. 836-43 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADAM12 overexpression does not improve outcome in mice with laminin alpha2-deficient muscular dystrophy
Guo, L. T., Shelton, G. D., Wewer, Ulla M. & Engvall, E., 1 Nov 2005, In: Neuromuscular Disorders. 15, 11, p. 786-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PINCH1 regulates cell-matrix and cell-cell adhesions, cell polarity and cell survival during the peri-implantation stage
Li, S., Bordoy, R., Stanchi, F., Moser, M., Braun, A., Kudlacek, O., Wewer, Ulla M., Yurchenco, P. D. & Fässler, R., 1 Jul 2005, In: Journal of Cell Science. 118, Pt 13, p. 2913-21 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADAM12 and alpha9beta1 integrin are instrumental in human myogenic cell differentiation
Lafuste, P., Sonnet, C., Chazaud, B., Dreyfus, P. A., Gherardi, R. K., Wewer, Ulla M. & Authier, F., 1 Feb 2005, In: Molecular Biology of the Cell. 16, 2, p. 861-70 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A role for ADAM12 in breast tumor progression and stromal cell apoptosis.
Kveiborg, Marie, Frohlich, C., Albrechtsen, Reidar, Tischler, V., Dietrich, N., Holck, P., Kronqvist, P., Rank, F., Mercurio, A. M. & Wewer, Ulla M., 2005, In: Cancer Research. 65, 11, p. 4754-61 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADAM12-mediated focal adhesion formation is differently regulated by beta1 and beta3 integrins.
Thodeti, C. K., Frohlich, C., Nielsen, C. K., Takada, Y., Fässler, R., Albrechtsen, Reidar & Wewer, Ulla M., 2005, In: FEBS Letters. 579, 25, p. 5589-95 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of IGF-II mRNA-binding proteins (IMPs) in gonads and testicular cancer
Hammer, N. A., Hansen, Thomas van Overeem, Byskov, A. G., Rajpert-De Meyts, E., Grøndahl, M. L., Bredkjaer, H. E., Wewer, Ulla M., Christiansen, Jan & Nielsen, Finn Cilius, 2005, In: Reproduction. 130, 2, p. 203-12 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hierarchy of ADAM12 binding to integrins in tumor cells.
Thodeti, C. K., Fröhlich, C., Nielsen, C. K., Holck, P., Sundberg, C., Kveiborg, Marie, Mahalingam, Y., Albrechtsen, Reidar, Couchman, John Robert & Wewer, Ulla M., 2005, In: Experimental Cell Research. 309, 2, p. 438-50 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduction of the disintegrin and metalloprotease ADAM12 in preeclampsia.
Laigaard, J., Sørensen, T., Placing, S., Holck, P., Frohlich, C., Wøjdemann, K. R., Sundberg, K., Shalmi, A., Tabor, A., Nørgaard-Pedersen, B., Ottesen, B., Christiansen, M. & Wewer, Ulla M., 2005, In: Obstetrics and Gynecology. 106, 1, p. 144-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The level of ADAM12-S in maternal serum is an early first-trimester marker of fetal trisomy 18.
Laigaard, J., Christiansen, M., Frohlich, C., Pedersen, B. N., Ottesen, B. & Wewer, Ulla M., 2005, In: Prenatal Diagnosis. 25, 1, p. 45-6 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
ADAM 12 cleaves extracellular matrix proteins and correlates with cancer status and stage
Roy, R., Wewer, Ulla M., Zurakowski, D., Pories, S. E. & Moses, M. A., 3 Dec 2004, In: Journal of Biological Chemistry. 279, 49, p. 51323-30 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dwarfism and impaired gut development in insulin-like growth factor II mRNA-binding protein 1-deficient mice
Hansen, Thomas van Overeem, Hammer, N. A., Nielsen, J., Madsen, Mette, Dalbaeck, C., Wewer, Ulla M., Christiansen, Jan & Nielsen, Finn Cilius, 2004, In: Molecular and Cellular Biology. 24, 10, p. 4448-64 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Moses MA. ADAM 12 cleaves ECM proteins: Correlation with cancer status and stage
Roy, R., Wewer, Ulla M., Zurakowski, D., Pories, S. E. & Moses, M. A., 2004, In: Journal of Biological Chemistry. 279, p. 51323-51330Research output: Contribution to journal › Journal article › Research
- Published
Regulation of ADAM12 cell-surface expression by protein kinase C epsilon.
Sundberg, C., Thodeti, C. K., Kveiborg, Marie, Larsson, C., Parker, P., Albrechtsen, Reidar & Wewer, Ulla M., 2004, In: Journal of Biological Chemistry. 279, 49, p. 51601-11 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
- Published
Compensation for dystrophin-deficiency: ADAM12 overexpression in skeletal muscle results in increased alpha 7 integrin, utrophin and associated glycoproteins
Moghadaszadeh, B., Albrechtsen, Reidar, Guo, L. T., Zaik, M., Kawaguchi, N., Borup, R. H., Kronqvist, P., Schroder, H. D., Davies, K. E., Voit, T., Nielsen, Finn Cilius, Engvall, E. & Wewer, Ulla M., 1 Oct 2003, In: Human Molecular Genetics. 12, 19, p. 2467-79 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
114th ENMC International Workshop on Congenital Muscular Dystrophy (CMD) 17-19 January 2003, Naarden, The Netherlands: (8th Workshop of the International Consortium on CMD; 3rd Workshop of the MYO-CLUSTER project GENRE)
Muntoni, F., Valero de Bernabe, B., Bittner, R., Blake, D., van Bokhoven, H., Brockington, M., Brown, S., Bushby, K., Campbell, K. P., Fiszman, M., Gruenewald, S., Merlini, L., Quijano-Roy, S., Romero, N., Sabatelli, P., Sewry, C. A., Straub, V., Talim, B., Topaloglu, H., Voit, T. & 4 others, , 1 Sep 2003, In: Neuromuscular Disorders. 13, 7-8, p. 579-88 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The new frontier in muscular dystrophy research: booster genes
Engvall, E. & Wewer, Ulla M., 1 Sep 2003, In: F A S E B Journal. 17, 12, p. 1579-84 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADAM12 in human liver cancers: TGF-beta-regulated expression in stellate cells is associated with matrix remodeling
Le Pabic, H., Bonnier, D., Wewer, Ulla M., Coutand, A., Musso, O., Baffet, G., Clément, B. & Théret, N., 1 May 2003, In: Hepatology. 37, 5, p. 1056-66 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selenoprotein N: an endoplasmic reticulum glycoprotein with an early developmental expression pattern
Petit, N., Lescure, A., Rederstorff, M., Krol, A., Moghadaszadeh, B., Wewer, Ulla M. & Guicheney, P., 1 May 2003, In: Human Molecular Genetics. 12, 9, p. 1045-53 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Laminin alpha2 deficiency and muscular dystrophy; genotype-phenotype correlation in mutant mice
Guo, L. T., Zhang, X. U., Kuang, W., Xu, H., Liu, L. A., Vilquin, J., Miyagoe-Suzuki, Y., Takeda, S., Ruegg, M. A., Wewer, Ulla M. & Engvall, E., 1 Mar 2003, In: Neuromuscular Disorders. 13, 3, p. 207-15 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADAM12 induces actin cytoskeleton and extracellular matrix reorganization during early adipocyte differentiation by regulating beta1 integrin function.
Kawaguchi, N., Sundberg, C., Kveiborg, Marie, Moghadaszadeh, B., Asmar, M., Dietrich, N., Thodeti, C. K., Nielsen, F. C., Möller, P., Mercurio, A. M., Albrechtsen, Reidar & Wewer, Ulla M., 2003, In: Journal of Cell Science. 116, Pt 19, p. 3893-904 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADAM12: a novel first-trimester maternal serum marker for Down syndrome.
Laigaard, J., Sørensen, T., Fröhlich, C., Pedersen, B. N., Christiansen, M., Schiøtt, K., Uldbjerg, N., Albrechtsen, Reidar, Clausen, H. V., Ottesen, B. & Wewer, Ulla M., 2003, In: Prenatal Diagnosis. 23, 13, p. 1086-91 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An endoplasmic reticulum glycoprotein with an early development expression pattern.
Petit, N., Lescure, A., Rederstorff, M., Krol, A., Moghadas Zadeh, S. B., Wewer, Ulla M. & Guicheney, P., 2003, In: Human Molecular Genetics. 12, p. 1045-1053Research output: Contribution to journal › Journal article › Research
- Published
Compensation for dystrophin-deficiency: ADAM12 overexpression in skeletal muscle results in increased alfa7 integrin, utrophin, and associated glycoproteins.
Moghadas Zadeh, S. B., Albrechtsen, Reidar, Guo, L. T., Zaik, M., Kawaguchi, N., Borup, R. H., Kronqvist, P. E., Schröder, H. D., Davies, K. E., Voit, T., Nielsen, F. C., Engvall, E. & Wewer, Ulla M., 2003, In: Human Molecular Genetics. 12, p. 2467-2479Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Laminin afra2 deficiency and muscular dystrophy: genotype-phenotype correlation in mutant mice.
Guo, L. T., Zhang, X. U., Kang, W., Xu, H., Liu, L. A., Miyagoe-Suzuki, Y., Takeda, S., Ruegg, M., Wewer, Ulla M. & Engvall, E., 2003, In: Neuromuscular Disorders. 13, p. 207-215Research output: Contribution to journal › Journal article › Research
- Published
The new frontier in muscular dystrophy: Booster genes.
Engvall, E. & Wewer, Ulla M., 2003, In: The FASEB Journal. 17, p. 1579-1584Research output: Contribution to journal › Journal article › Research
- 2002
- Published
98th ENMC International Workshop on Congenital Muscular Dystrophy (CMD), 7th Workshop of the International Consortium on CMD, 2nd Workshop of the MYO CLUSTER project GENRE. 26-28th October, 2001, Naarden, The Netherlands
Muntoni, F., Bertini, E., Bönnemann, C., Brockington, M., Brown, S., Bushby, K., Fiszman, M., Körner, C., Mercuri, E., Merlini, L., Hewitt, J., Quijano-Roy, S., Romero, N., Squarzoni, S., Sewry, C. A., Straub, V., Topaloglu, H., Haliloglu, G., Voit, T., Wewer, U. & 1 others, , 1 Nov 2002, In: Neuromuscular Disorders. 12, 9, p. 889-96 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADAM12 alleviates the skeletal muscle pathology in mdx dystrophic mice
Kronqvist, P., Kawaguchi, N., Albrechtsen, Reidar, Xu, X., Schrøder, H. D., Moghadaszadeh, B., Nielsen, Finn Cilius, Frohlich, C., Engvall, E. & Wewer, Ulla M., 1 Nov 2002, In: American Journal of Pathology. 161, 5, p. 1535-40 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
98th ENMC International Workshop on congenital Muscular Dystrophy (CMD)
Muntoni, F., Bertine, E., Bonnemann, C., Brockington, M., Bushby, K., Fiszman, M., Korner, C., Mercuri, E., Merlini, L., Hewitt, J., Quijano-Roy, S., Romero, N., Squarzoni, S., Sewry, C. A., Straub, V., Hopaloglu, H., Haliloglu, G., Voit, T., Wewer, Ulla M. & Guicheney, P., 2002, In: Neuromuscular Disorders. 12, p. 889-896Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADAM 12 alleviates the skeletal muscle 0pathology in mdx dystrophic mice
Kronqvist, P. E., Kawaguchi, N., Albrechtsen, Reidar, Xu, X., Schrøder, H. D., Moghadas Zadeh, S. B., Nielsen, F. C., Frohlich, L. C., Engvall, E. & Wewer, Ulla M., 2002, In: American Journal of Pathology. 161, p. 1535-1540Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADAM 12 protease induces adipogenesis in transgenic mice.
Kawaguchi, N., Xu, X., Tajima, R., Kronqvist, P., Sundberg, C., Loechel, F., Albrechtsen, Reidar & Wewer, Ulla M., 2002, In: American Journal of Pathology. 160, 5, p. 1895-903 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADAM12/syndecan-4 signaling promotes beta 1 integrin-dependent cell spreading through protein kinase Calpha and RhoA.
Thodeti, C. K., Albrechtsen, Reidar, Grauslund, M., Asmar, M., Larsson, C., Takada, Y., Mercurio, A. M., Couchman, John Robert & Wewer, Ulla M., 2002, In: Journal of Biological Chemistry. 278, 11, p. 9576-84 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tetranectin
Wewer, Ulla M. & Albrechtsen, Reidar, 2002, In: Wiley Encyclopedia of Molecular Medicine. 5, p. 3117-3118Research output: Contribution to journal › Journal article › Research
- 2001
- Published
Activation of ADAM 12 protease by copper
Loechel, F. & Wewer, Ulla M., 2001, In: FEBS Letters. 506, 1, p. 65-68 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
E2F repression by C/EBPalpha is required for adipogenesis and granulopoiesis in vivo.
Porse, Bo Torben, Pedersen TA, Xu, X., Lindberg, B., Wewer, Ulla M., Friis-Hansen, L. & Nerlov, C., 2001, In: Cell. 107, 2, p. 247-58 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mice with a targeted deletion of the tetranectin gene exhibit a spinal deformity.
Iba, K., Durkin, M. E., Johnsen, L., Hunziker, E., Damgaard-Pedersen, K., Zhang, H., Engvall, E., Albrechtsen, Reidar & Wewer, Ulla M., 2001, In: Molecular and Cellular Biology. 21, 22, p. 7817-25 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of laminin beta2 chain gene expression in human cancer cell lines.
Durkin, M. E., Nielsen, F. C., Loechel, F., Albrechtsen, Reidar & Wewer, Ulla M., 2001, In: European Journal of Biochemistry. 268, 13, p. 3797-806 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tetranectin in slow intra- and extrafusal chicken muscle fibers.
Xu, X., Gilpin, B., Iba, K., Maier, A., Engvall, E., Albrechtsen, Reidar & Wewer, Ulla M., 2001, In: Journal of Muscle Research and Cell Motility. 22, 2, p. 121-32 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2000
- Published
Binding of ADAM12, a marker of skeletal muscle regeneration, to the muscle-specific actin-binding protein, alpha -actinin-2, is required for myoblast fusion
Galliano, M. F., Huet, C., Frygelius, J., Polgren, A., Wewer, Ulla M. & Engvall, E., 5 May 2000, In: Journal of Biological Chemistry. 275, 18, p. 13933-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADAM 12, a disintegrin metalloprotease, interacts with insulin-like growth factor-binding protein-3
Shi, Z., Xu, W., Loechel, F., Wewer, Ulla M. & Murphy, L., 2000, In: Journal of Biological Chemistry. 275, 24, p. 18574-18580Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADAM 12-S cleaves IGFBP-3 and IGFBP-5 and is inhibited by TIMP-3.
Loechel, F., Fox, J. W., Murphy, G., Albrechtsen, Reidar & Wewer, Ulla M., 2000, In: Biochemical and Biophysical Research Communications. 278, 3, p. 511-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Binding of ADAM12, a marker for skeletal muscle regeneration, to the muscle-specific actin-binding protein, alfa-actinin-2, is required for myoblast fusion.
Galliano, H., Frygelius, J., Polgren, A. & Wewer, Ulla M., 2000, In: Journal of Biological Chemistry. 275, p. 13933-13999Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Celle-matrix-interaktioner ved cancer
Wewer, Ulla M., 2000, In: Ugeskrift for læger. 162, 36, p. 4783-5 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
H19 RNA binds four molecules of insulin-like growth factor II mRNA-binding protein
Runge, S., Nielsen, Finn Cilius, Nielsen, J., Andersen, J. L., Wewer, Ulla M. & Christiansen, Jan, 2000, In: Journal of Biological Chemistry. 275, 38, p. 29562-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The cysteine-rich domain of human ADAM 12 supports cell adhesion through syndecans and triggers signaling events that lead to beta1 integrin-dependent cell spreading.
Iba, K., Albrechtsen, Reidar, Gilpin, B., Frohlich, C., Loechel, F., Zolkiewska, A., Ishiguro, K., Kojima, T., Liu, W., Langford, J. K., Sanderson, R. D., Brakebusch, Cord Herbert, Fässler, R. & Wewer, Ulla M., 2000, In: Journal of Cell Biology. 149, 5, p. 1143-56 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Trafficking of human ADAM 12-L: retention in the trans-Golgi network.
Hougaard, S., Loechel, F., Xu, X., Tajima, R., Albrechtsen, Reidar & Wewer, Ulla M., 2000, In: Biochemical and Biophysical Research Communications. 275, 2, p. 261-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1999
- Published
A family of insulin-like growth factor II mRNA-binding proteins represses translation in late development
Nielsen, J., Christiansen, Jan, Lykke-Andersen, J., Johnsen, A. H., Wewer, Ulla M. & Nielsen, Finn Cilius, 1999, In: Molecular and Cellular Biology. 19, 2, p. 1262-1270 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of the human laminin beta2 chain locus (LAMB2): linkage to a gene containing a nonprocessed, transcribed LAMB2-like pseudogene (LAMB2L) and to the gene encoding glutaminyl tRNA synthetase (QARS).
Durkin, M. E., Jäger, A. C., Khurana, T. S., Nielsen, F. C., Albrechtsen, Reidar & Wewer, Ulla M., 1999, In: Cytogenetic and Genome Research. 84, 3-4, p. 173-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cysteine-rich domain of human ADAM 12 (meltrin alpha) supports tumor cell adhesion.
Iba, K., Albrechtsen, Reidar, Gilpin, B. J., Loechel, F. & Wewer, Ulla M., 1999, In: American Journal of Pathology. 154, 5, p. 1489-501 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of human ADAM 12 protease by the prodomain. Evidence for a functional cysteine switch.
Loechel, F., Overgaard, M. T., Oxvig, C., Albrechtsen, Reidar & Wewer, Ulla M., 1999, In: Journal of Biological Chemistry. 274, 19, p. 13427-33 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1998
- Published
Laminin alpha2 chain-deficient congenital muscular dystrophy: variable epitope expression in severe and mild cases
Cohn, R. D., Herrmann, R., Sorokin, L., Wewer, Ulla M. & Voit, T., 1 Jul 1998, In: Neurology. 51, 1, p. 94-100 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Congenital myasthenic syndromes in two kinships with end-plate acetylcholine receptor and utrophin deficiency
Sieb, J. P., Dörfler, P., Tzartos, S., Wewer, Ulla M., Rüegg, M. A., Meyer, D., Baumann, I., Lindemuth, R., Jakschik, J. & Ries, F., 1 Jan 1998, In: Neurology. 50, 1, p. 54-61 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A novel, secreted form of human ADAM 12 (meltrin alpha) provokes myogenesis in vivo.
Gilpin, B. J., Loechel, F., Mattei, M. G., Engvall, E., Albrechtsen, Reidar & Wewer, Ulla M., 1998, In: Journal of Biological Chemistry. 273, 1, p. 157-66 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Congenital myastenic syndromes in two kinships with endplate acetylcholine receptor and utropin deficiency
Sieb, J. P., Dörfler, P., Tzartos, S., Wewer, Ulla M., Rüegg, M. A., Meyer, D., Baumann, I. & Lindemuth, R., 1998, In: Neurology. 50, p. 54-61Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of Lama5 as a candidate for the mouse ragged (Ra) mutation.
Durkin, M. E., Albrechtsen, Reidar, Chambers, D. M., Abbott, C. M. & Wewer, Ulla M., 1998, In: Biochemical and Biophysical Research Communications. 250, 1, p. 125-30 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic correction of merosin deficiency in the dy2J mouse model of congenital muscular dystrophy. Partial genetic correction in two models
Kuang, W., Xu, H., Vachon, P. H., Liu, L., Loechel, F., Wewer, Ulla M. & Engvall, E., 1998, In: Journal of Clinical Investigation. 102, p. 844-852Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human ADAM 12 (meltrin alpha) is an active metalloprotease.
Loechel, F., Gilpin, B. J., Engvall, E., Albrechtsen, Reidar & Wewer, Ulla M., 1998, In: Journal of Biological Chemistry. 273, 27, p. 16993-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Laminin alpha2 chain-deficient muscular dystrophy: variable epitope expression in severe and mild cases
Cohn, R. D., Herrmann, R. J., Sorokin, L., Wewer, Ulla M. & Voit, T., 1998, In: Neurology. 51, p. 94-100Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Merosin-deficient congenital muscular dystrophy. Partial genetic correction in two mouse models
Kuang, W., Xu, H., Vachon, P. H., Liu, L., Loechel, F., Wewer, Ulla M. & Engvall, E., 1998, In: Journal of Clinical Investigation. 102, 4, p. 844-52 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tetranectin is a novel marker for myogenesis during embryonic development, muscle regeneration, and muscle cell differentiation in vitro.
Wewer, Ulla M., Iba, K., Durkin, M. E., Nielsen, F. C., Loechel, F., Gilpin, B. J., Kuang, W., Engvall, E. & Albrechtsen, Reidar, 1998, In: Developmental Biology. 200, 2, p. 247-59 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1997
- Published
Integrins (alpha7beta1) in muscle function and survival. Disrupted expression in merosin-deficient congenital muscular dystrophy
Vachon, P. H., Xu, H., Liu, L., Loechel, F., Hayashi, Y., Arahata, K., Reed, J. C., Wewer, Ulla M. & Engvall, E., 1 Oct 1997, In: Journal of Clinical Investigation. 100, 7, p. 1870-81 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Changes of laminin beta 2 chain expression in congenital muscular dystrophy
Cohn, R. D., Herrmann, R., Wewer, Ulla M. & Voit, T., 1 Sep 1997, In: Neuromuscular Disorders. 7, 6-7, p. 373-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Phosphorylation and Distribution of Cortactin Downstream of Integrin α9β1 Affects Cancer Cell Behaviour
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