Jakob Werner Hansen

Jakob Werner Hansen

Senior Researcher

ORCID: 0000-0002-7315-3775

Publication year:
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1 - 35 out of 35Page size: 50
  1. 2023
  2. Published

    Overall Survival in Patients with Ccus Depends on Presence of Anemia

    Træden, D., Tulstrup, Morten Rytter, Johansen, Morten Munk, mxz703, mxz703, Marcher, C., Raaschou-jensen, K., Stidsholt Roug, A., Severinsen, M. T., Porse, Bo Torben, Theilgaard-Mønch, Kim, Jespersen, J., Cowland, J. B., Sjö, Lene Dissing, Andersen, M. K., Grønbæk, Kirsten & Hansen, Jakob Werner, 28 Nov 2023, In: Blood. 142, Supplement 1, p. 1864-1864

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Frequency and Functional Characterization of RUNX1 Germline Variants in Myeloid Neoplasms

    Nitschke, N. J., Almosailleakh, M., Niu, Yiyuan, Hansen, Jakob Werner, Raaschou-Jensen, K., Jespersen, Jakob Schmidt, Severinsen, M. T., Roug, A. S., Frödin, Morten, Weischenfeldt, Joachim Lütken, Andersen, M. K. & Grønbæk, Kirsten, 2023, In: Human Mutation. 2023, 11 p., 4738660.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    LEP promoter methylation in the initiation and progression of clonal cytopenia of undetermined significance and myelodysplastic syndrome

    Kaastrup, K., Gillberg, Linn, Mikkelsen, Stine Ulrik, mxz703, mxz703, Schöllkopf, C., Mortensen, B. K., Porse, Bo Torben, Hansen, Jakob Werner & Grønbæk, Kirsten, 2023, In: Clinical Epigenetics. 15, 13 p., 91.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    ProGraME: A novel flow cytometry algorithm for the diagnosis of low-risk myelodysplastic syndromes in patients with cytopenia

    Therkelsen, J., Træden, D. W., Schjødt, I., Andersen, M. K., Sjö, Lene Dissing, Hansen, Jakob Werner, Grønbæk, Kirsten & Dimopoulos, K., 2023, In: European Journal of Haematology. 111, 6, 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. E-pub ahead of print

    Treatment experiences with focus on IL-6R inhibition in patients with VEXAS-syndrome and a case of remission with azacytidine treatment

    Johansen, Morten Munk, Fassi, Daniel El , Nielsen, Christoffer Tandrup Holst, Krintel, S. B., Graudal, N. & Hansen, Jakob Werner, 2023, (E-pub ahead of print) In: Rheumatology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. 2022
  8. Published

    Clonal Hematopoiesis and Epigenetic Age Acceleration in Elderly Danish Twins

    Sørensen, M., Tulstrup, Morten Rytter, Hansen, Jakob Werner, Weischenfeldt, Joachim Lütken, Grønbæk, Kirsten & Christensen, K., 2022, In: HemaSphere. 6, 9, 6 p., 768.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Inflammatory Cytokine Profiles Do Not Differ Between Patients With Idiopathic Cytopenias of Undetermined Significance and Myelodysplastic Syndromes

    Nielsen, A. B., Hansen, Jakob Werner, mxz703, mxz703, Dimopoulos, K., Salem, M., Grigorian, M., Bruunsgaard, Helle & Grønbæk, Kirsten, 2022, In: HemaSphere. 6, 5, 10 p., e0713.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Safety, Outcomes, and T-Cell Characteristics in Patients with Relapsed or Refractory MDS or CMML Treated with Atezolizumab in Combination with Guadecitabine

    O'Connell, C. L., Baer, M. R., Ørskov, A. D., Saini, S. K., Duong, V. H., Kropf, P., Hansen, J. W., Tsao-Wei, D., Jang, H. S., Emadi, A., Holmberg-Thyden, S., Cowland, J., Brinker, B. T., Horwood, K., Burgos, R., Hostetter, G., Youngblood, B. A., Hadrup, S. R., Issa, J. P., Jones, P. & 3 others, Baylin, S. B., Siddiqi, I. & Grønbæk, Kirsten, 2022, In: Clinical cancer research : an official journal of the American Association for Cancer Research. 28, 24, p. 5306-5316 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. 2021
  12. Published

    Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Myelomonocytic Leukemia: Clinical and Molecular Genetic Prognostic Factors in a Nordic Population

    Wedge, E., Hansen, J. W., Dybedal, I., Creignou, M., Ejerblad, E., Lorenz, F., Werlenius, O., Ungerstedt, J., Holm, M. S., Nilsson, L., Kittang, A. O., Antunovic, P., Rohon, P., Andersen, M. K., Papaemmanuil, E., Bernard, E., Jädersten, M., Hellström-Lindberg, E., Grønbæk, K., Ljungman, P. & 1 others, Friis, L. S., 2021, In: Transplantation and Cellular Therapy. 27, 12, p. 991.e1-991.e9

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Mutations known from B-cell lymphoid malignancies are not found in CD34+ stem cells from patients with lymphoma

    Husby, Simon, Favero, Francesco, Rodriguez Gonzalez, Francisco G, Sutton, L. A., Haastrup, E. K., mxz703, mxz703, Hansen, Jakob Werner, Arboe, B., Aslan, D., Clasen-Linde, E., Gjerdrum, Lise Mette Rahbek, Gørlev, J. S., Brown, Peter de Nully, Fischer-Nielsen, A., Rosenquist, R., Weischenfeldt, Joachim Lütken & Grønbæk, Kirsten, 2021, In: Leukemia and Lymphoma. 62, 11, p. 2808-2811

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Structural aberrations are associated with poor survival in patients with clonal cytopenia of undetermined significance

    Mikkelsen, Stine Ulrik, Safavi, S., Dimopoulos, K., O'Rourke, Colm, Andersen, M. K., Holm, M. S., Marcher, C. W., Andersen, Jesper Bøje, Hansen, Jakob Werner & Grønbæk, Kirsten, 2021, In: Haematologica. 106, 6

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  15. Published

    TET2 mutations are associated with hypermethylation at key regulatory enhancers in normal and malignant hematopoiesis

    Tulstrup, Morten Rytter, Soerensen, M., Hansen, Jakob Werner, Gillberg, Linn, Needhamsen, M., Kaastrup, K., Helin, K., Christensen, K., Weischenfeldt, Joachim Lütken & Grønbæk, Kirsten, 2021, In: Nature Communications. 12, 1, 10 p., 6061.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. 2020
  17. Published

    Clinical impact of clonal hematopoiesis in patients with lymphoma undergoing ASCT: a national population-based cohort study

    Husby, S., Favero, F., Nielsen, C., Sørensen, B. S., Bæch, J., Grell, K., Hansen, J. W., Rodriguez-Gonzalez, F. G., Haastrup, E. K., Fischer-Nielsen, A., Andersen, P., Arboe, B., Sækmose, S. G., Hansen, P. B., Christiansen, I., Clasen-Linde, E., Meldgaard, L., Ebbesen, L. H., Segel, E. K., Josefsson, P. & 6 others, Thorsgaard, M., El-Galaly, T. C., Brown, Peter de Nully, Weischenfeldt, Joachim Lütken, Larsen, T. S. & Grønbæk, Kirsten, 2020, In: Leukemia. 34, p. 3256-3268 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Clonal hematopoiesis in elderly twins: concordance, discordance, and mortality

    Hansen, Jakob Werner, Pedersen, D. A., Larsen, L. A., Husby, Simon, Clemmensen, S. B., Hjelmborg, J., Favero, Francesco, Weischenfeldt, Joachim Lütken, Christensen, K. & Grønbæk, Kirsten, 2020, In: Blood. 135, 4, p. 261-268

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Improved Outcomes after Allogenic Hematopoietic Stem Cell Transplantation with Fludarabine/Treosulfan for Patients with Myelodysplastic Syndromes

    Wedge, E., Sengeløv, Henrik, Hansen, Jakob Werner, Andersen, N. S., Schjødt, I., Petersen, S. L., Kornblit, B., Grønbæk, Kirsten & Friis, L. S., 2020, In: Biology of Blood and Marrow Transplantation. 26, 6, p. 1091-1098

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    The diagnostic and prognostic role of flow cytometry in idiopathic and clonal cytopenia of undetermined significance (ICUS/CCUS): A single-center analysis of 79 patients

    Dimopoulos, K., Hansen, O. K., Sjö, Lene Dissing, Saft, L., Schjødt, I. M., Hansen, Jakob Werner & Grønbæk, Kirsten, 2020, In: Cytometry. Part B: Clinical Cytometry. 98, 3, p. 250-258

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    The value of circulating microRNAs for early diagnosis of B-cell lymphoma: A case-control study on historical samples

    Jørgensen, S., Paulsen, I. W., Hansen, Jakob Werner, Tholstrup, Dorte Maegaard, Hother, C., Sørensen, E., Petersen, M. S., Nielsen, K. R., Rostgaard, K., Larsen, M. A. H., Brown, Peter de Nully, Ralfkiær, E., Homburg, K. M., Hjalgrim, Henrik, Erikstrup, C., Ullum, H., Troelsen, J., Grønbæk, Kirsten & Pedersen, Ole Birger Vesterager, 2020, In: Scientific Reports. 10, 1, 9637.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. 2019
  23. Published

    Oral vitamin C supplementation to patients with myeloid cancer on azacitidine treatment: Normalization of plasma vitamin C induces epigenetic changes

    Gillberg, Linn, mxz703, mxz703, Nasif, A., Ohtani, H., Madaj, Z., Hansen, Jakob Werner, Rapin, N., Mogensen, J. B., Liu, M., Dufva, I. H., Lykkesfeldt, Jens, Hajkova, P., Jones, P. A. & Grønbæk, Kirsten, 17 Oct 2019, In: Clinical Epigenetics. 11, 1, p. 143-153 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. 2018
  25. Published

    Clinical Impact of Clonal Hematopoiesis after Autologous Stem Cell Transplantation for Lymphoma: A National Population-Based Cohort Study

    Husby, S., Francesco, F., Nielsen, C., Sorensen, B., Baech, J., Hansen, J. W., Gonzalez, G. G. R., Arboe, B., Andersen, L. P., Hastrup, E. K., Fischer-Nielsen, A., Saekmose, S. G., Hansen, P. B., Christiansen, I., Clasen-Linde, E., Knudsen, L. M., Grell, K., Segel, E. K., Ebbesen, L. H., Thorsgaard, M. & 6 others, Josefsson, P. L., El-Galaly, T. C., Brown, Peter de Nully, Weisenfeldt, J., Larsen, T. S. & Grønbæk, Kirsten, 2018, In: Blood. 132, Suppl 1, p. 607 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  26. Published

    Long-term clinical outcomes of patients with hematologically unexplained cytopenia after routine assessment: A single center study

    Johansen, M. M., Andersen, M. A., Grønbæk, Kirsten & Hansen, Jakob Werner, 2018, In: European Journal of Haematology. 101, 5, p. 595–603 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Treatment strategies, outcomes and prognostic factors in 291 patients with secondary CNS involvement by diffuse large B-cell lymphoma

    El-Galaly, T. C., Cheah, C. Y., Bendtsen, M. D., Nowakowski, G. S., Kansara, R., Savage, K. J., Connors, J. M., Sehn, L. H., Goldschmidt, N., Shaulov, A., Farooq, U., Link, B. K., Ferreri, A. J. M., Calimeri, T., Cecchetti, C., Dann, E. J., Thompson, C. A., Inbar, T., Maurer, M. J., Gade, I. L. & 14 others, Juul, M. B., Hansen, Jakob Werner, Holmberg, S., Larsen, T. S., Cordua, S., Mikhaeel, N. G., Hutchings, M., Seymour, J. F., Clausen, M. R., Smith, D., Opat, S., Gilbertson, M., Thanarajasingam, G. & Villa, D., 2018, In: European Journal of Cancer. 93, p. 57-68 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. 2017
  29. Published

    Anemia is present years before myelodysplastic syndrome diagnosis: Results from the pre-diagnostic period

    Hansen, Jakob Werner, Sandholdt, H., Siersma, Volkert Dirk, mxz703, mxz703, Holmberg, S., Bjerrum, O. W., Hasselbalch, Hans Carl, Olivarius, Niels de Fine, Grønbæk, Kirsten & Andersen, Christen Bertel L, Jul 2017, In: American Journal of Hematology. 92, 7, p. E130-E132 3 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  30. Published

    Global hypomethylation is an independent prognostic factor in diffuse large B cell lymphoma

    Wedge, E., Hansen, Jakob Werner, Garde, C., Asmar, F., Tholstrup, Dorte Maegaard, Kristensen, S. S., Munch-Petersen, H. D., Ralfkiaer, E., Brown, Peter de Nully, Grønbæk, Kirsten & Kristensen, L. S., Jul 2017, In: American Journal of Hematology. 92, 7, p. 689-694 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    TP53 mutations identify younger mantle cell lymphoma patients who do not benefit from intensive chemoimmunotherapy

    Eskelund, C. W., Dahl, C., Hansen, Jakob Werner, Westman, M., Kolstad, A., Pedersen, L. B., Montano-Almendras, C. P., Husby, Simon, Freiburghaus, C., Ek, S., Vestergaard, Anja Holm, Niemann, Carsten, Raty, R., Brown, Peter de Nully, Geisler, C. H., Andersen, M. K., Guldberg, P., Jerkeman, M. & Grønbæk, Kirsten, 2017, In: Blood. 130, 17, p. 1903-1910 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. 2016
  33. Published

    Mutations in idiopathic cytopenia of undetermined significance assist diagnostics and correlate to dysplastic changes

    Hansen, Jakob Werner, Westman, M. K., Sjö, Lene Dissing, Saft, L., Sommer Kristensen, L., mxz703, mxz703, Treppendahl, M., Andersen, M. K. & Grønbæk, Kirsten, Dec 2016, In: American Journal of Hematology. 91, 12, p. 1234-1238 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Uterine, but not ovarian, female reproductive organ involvement at presentation by diffuse large B-cell lymphoma is associated with poor outcomes and a high frequency of secondary CNS involvement

    El-Galaly, T. C., Cheah, C. Y., Hutchings, M., Mikhaeel, N. G., Savage, K. J., Sehn, L. H., Barrington, S. F., Hansen, J. W., Poulsen, M. Ø., Smith, D. L., Rady, K., Mylam, K. J., Larsen, T. S., Holmberg, S., Juul, M. B., Cordua, S., Clausen, M. R., Jensen, K. B., Boegsted, M., Johnsen, H. E. & 4 others, Seymour, J. F., Connors, J. M., Brown, Peter de Nully & Villa, D., Dec 2016, In: British Journal of Haematology. 175, 5, p. 876-883 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Immune Mechanisms in Myelodysplastic Syndrome

    Glenthøj, A., mxz703, mxz703, Hansen, Jakob Werner, Hadrup, S. R., O'Connell, C. & Grønbæk, Kirsten, 15 Jun 2016, In: International Journal of Molecular Sciences (Online). 17, 6, 13 p., 944.

    Research output: Contribution to journal › Review › Research › peer-review

  36. Published

    The value of routine bone marrow biopsy in patients with diffuse large B-cell lymphoma staged with PET/CT: a Danish-Canadian study

    Alzahrani, M., El-Galaly, T. C., Hutchings, M., Hansen, Jakob Werner, Loft, A., Johnsen, H. E., Iyer, V., Wilson, D., Sehn, L. H., Savage, K. J., Connors, J. M., Gascoyne, R. D., Johansen, P., Clasen-Linde, E., Brown, P. & Villa, D., Jun 2016, In: Annals of Oncology. 27, 6, p. 1095-9 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Aberrant methylation of cell-free circulating DNA in plasma predicts poor outcome in diffuse large B cell lymphoma

    Sommer Kristensen, L., Hansen, Jakob Werner, Kristensen, S. S., Tholstrup, D., Harsløf, L. B. S., Pedersen, Ole Birger Vesterager, Brown, Peter de Nully & Grønbæk, Kirsten, 2016, In: Clinical Epigenetics. 8, 11 p., 95.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Tumor suppressor microRNAs are downregulated in myelodysplastic syndrome with spliceosome mutations

    Aslan, D., Garde, C., Nygaard, M. K., Helbo, A. S., Dimopoulos, K., Hansen, Jakob Werner, Severinsen, M. T., Treppendahl, M. B., Sjö, Lene Dissing, Grønbæk, Kirsten & Sommer Kristensen, L., 2016, In: OncoTarget. 7, 9, p. 9951-63 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. 2015
  40. Published

    Outcome prediction by extranodal involvement, IPI, and R-IPI in the PET/CT and rituximab era: A Danish-Canadian study of 443 patients with diffuse-large B-cell lymphoma

    El-Galaly, T. C., Villa, D., Alzahrani, M., Hansen, Jakob Werner, Sehn, L. H., Wilson, D., de Nully Brown, P., Loft, A., Iyer, V., Johnsen, H. E., Savage, K. J., Connors, J. M. & Hutchings, M., Nov 2015, In: American Journal of Hematology. 90, 11, p. 1041–1046

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    YKL-40 and genetic status of CHI3L1 in a large group of asthmatics

    Hansen, Jakob Werner, Thomsen, Simon Francis, Porsbjerg, Celeste Michala, Rasmussen, L. M., Harmsen, L., Johansen, Julia Sidenius & Backer, Vibeke, 2015, In: European Clinical Respiratory Journal. 2, p. 1-8 8 p., 25117.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. 2014
  43. Published

    Hypermethylation of DAPK1 is an independent prognostic factor predicting survival in diffuse large B-cell lymphoma

    Kristensen, L. S., Asmar, F., Dimopoulos, K., Nygaard, M. K., Aslan, D., Hansen, Jakob Werner, Ralfkiaer, E. & Grønbæk, Kirsten, 2014, In: OncoTarget. 5, 20, p. 9798-810 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. 2010
  45. Published

    Rhinitis: a complication to asthma

    Hansen, Jakob Werner, Thomsen, Simon Francis, Nolte, H. & Backer, Vibeke, Jul 2010, In: Allergy. 65, 7, p. 883-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. 2009
  47. Published

    Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction

    Gudbjartsson, D. F., Bjornsdottir, U. S., Halapi, E., Helgadottir, A., Sulem, P., Jonsdottir, G. M., Thorleifsson, G., Helgadottir, H., Steinthorsdottir, V., Stefansson, H., Williams, C., Hui, J., Beilby, J., Warrington, N. M., James, A., Palmer, L. J., Koppelman, G. H., Heinzmann, A., Krueger, M., Boezen, H. M. & 53 others, Wheatley, A., Altmuller, J., Shin, H. D., Uh, S., Cheong, H. S., Jonsdottir, B., Gislason, D., Park, C., Rasmussen, L. M., Porsbjerg, Celeste Michala, Hansen, Jakob Werner, Backer, Vibeke, Werge, Thomas, Janson, C., Jönsson, U., Ng, M. C. Y., Chan, J., So, W. Y., Ma, R., Shah, S. H., Granger, C. B., Quyyumi, A. A., Levey, A. I., Vaccarino, V., Reilly, M. P., Rader, D. J., Williams, M. J. A., van Rij, A. M., Jones, G. T., Trabetti, E., Malerba, G., Pignatti, P. F., Boner, A., Pescollderungg, L., Girelli, D., Olivieri, O., Martinelli, N., Ludviksson, B. R., Ludviksdottir, D., Eyjolfsson, G. I., Arnar, D., Thorgeirsson, G., Deichmann, K., Thompson, P. J., Wjst, M., Hall, I. P., Postma, D. S., Gislason, T., Gulcher, J., Kong, A., Jonsdottir, I., Thorsteinsdottir, U. & Stefansson, K., Mar 2009, In: Nature Genetics. 41, 3, p. 342-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

ID: 129470785