Konstantin Khodosevich

Konstantin Khodosevich

Group leader, Professor

Member of:

    ORCID: 0000-0001-7232-5558

    Publication year:
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    1 - 25 out of 56Page size: 25
    1. 2024
    2. Published

      Drug targeting in psychiatric disorders — how to overcome the loss in translation?

      Khodosevich, Konstantin, Dragicevic, K. & Howes, O., 2024, In: Nature Reviews Drug Discovery. 23, p. 218-231

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. 2023
    4. Published

      A maturational shift in the frontal cortex synaptic transcriptional landscape underlies schizophrenia-relevant behavioural traits: A congenital rat model

      Sønderstrup, M., Batiuk, M. Y., Mantas, P., Tapias-Espinosa, C., Oliveras, I., Cañete, T., Sampedro-Viana, D., Brudek, T., Rydbirk, Rasmus, Khodosevich, Konstantin, Fernandez-Teruel, A., Elfving, B. & Aznar, S., 2023, In: European Neuropsychopharmacology. 74, p. 32-46 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Loss of maturity and homeostatic functions in Tuberous Sclerosis Complex-derived astrocytes

      Luinenburg, M. J., Scheper, M., Sørensen, Frederik Nørby Friis, Anink, J. J., Van Hecke, W., Korshunova, Irina, Jansen, F. E., Riney, K., van Eijsden, P., Gosselaar, P., Mills, J. D., Kalf, R. S., Zimmer, T. S., Broekaart, D. W. M., Khodosevich, Konstantin, Aronica, E. & Mühlebner, A., 2023, In: Frontiers in Cellular Neuroscience. 17, 15 p., 1284394.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Neurodevelopmental disorders - high-resolution rethinking of disease modeling

      Khodosevich, Konstantin & Sellgren, C. M., 2023, In: Molecular Psychiatry. 28, p. 34-43 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. 2022
    8. Published

      Cell segmentation in imaging-based spatial transcriptomics

      Petukhov, V., Xu, R. J., Soldatov, R. A., Cadinu, P., Khodosevich, Konstantin, Moffitt, J. R. & Kharchenko, P. V., 2022, In: Nature Biotechnology. 40, p. 345-354

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Ductal keratin 15+ luminal progenitors in normal breast exhibit a basal-like breast cancer transcriptomic signature

      Kohler, Katharina Theresa, Goldhammer, N., Demharter, S., Pfisterer, U., Khodosevich, Konstantin, Rønnov-Jessen, Lone, Petersen, Ole William, Villadsen, René & Kim, Jiyoung, 2022, In: npj Breast Cancer. 8, 1, 12 p., 81.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Expression profile of synaptic vesicle glycoprotein 2A, B, and C paralogues in temporal neocortex tissue from patients with temporal lobe epilepsy (TLE)

      Pazarlar, B. A., trj450, trj450, Petukhov, V., Pinborg, Lars Hageman, Khodosevich, Konstantin & Mikkelsen, Jens D., 2022, In: Molecular Brain. 15, 1, 45.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Identification of Vulnerable Interneuron Subtypes in 15q13.3 Microdeletion Syndrome Using Single-Cell Transcriptomics

      Malwade, S., Gasthaus, J., Bellardita, Carmelo, Andelic, M., Moric, Borna, Korshunova, Irina, Kiehn, Ole, Vasistha, Navneet A & Khodosevich, Konstantin, 2022, In: Biological Psychiatry. 91, 8, p. 727-739

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Production of human entorhinal stellate cell-like cells by forward programming shows an important role of Foxp1 in reprogramming

      Bergmann, T., Liu, Y., Skov, J., Mogus, L., Lee, J., Pfisterer, U., Handfield, L. F., Asenjo-Martinez, A., Lisa-Vargas, I., Seemann, S. E., Lee, J. T. H., Patikas, N., Kornum, B. R., Denham, M., Hyttel, P., Witter, M. P., Gorodkin, J., Pers, T. H., Hemberg, M., Khodosevich, K. & 1 others, Hall, Vanessa Jane, 2022, In: Frontiers in Cell and Developmental Biology. 10, 976549.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Single-nucleus transcriptomics of IDH1- and TP53-mutant glioma stem cells displays diversified commitment on invasive cancer progenitors: [Inkl. correction]

      Gulaia, V., Shmelev, M., Romanishin, A., Shved, N., Farniev, V., Goncharov, N., Biktimirov, A., Lisa Vargas, Irene, Khodosevich, Konstantin, Kagansky, A. & Kumeiko, V., 2022, In: Scientific Reports. 12, 18 p., 18975.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Upper cortical layer-driven network impairment in schizophrenia

      Batiuk, M. Y., Tyler, T., Dragicevic, K., Mei, S., Rydbirk, Rasmus, Petukhov, V., Deviatiiarov, R., Sedmak, D., Frank, E., Feher, V., Habek, N., Hu, Q., Igolkina, A., Roszik, L., Pfisterer, U., Garcia-Gonzalez, D., Petanjek, Z., Adorjan, I., Kharchenko, P. V. & Khodosevich, Konstantin, 2022, In: Science Advances. 8, 41, 24 p., eabn8367.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. 2021
    16. Published

      Coordinated maintenance of H3K36/K27 methylation by histone demethylases preserves germ cell identity and immortality

      Zaghet, Nico, Madsen, Katrine, Rossi, F., Perez, D. F., Amendola, P. G., Demharter, S., Pfisterer, U., Khodosevich, Konstantin, Pasini, D. & Salcini, Anna Elisabetta, 2021, In: Cell Reports. 37, 8, p. 110050

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Development of the entorhinal cortex occurs via parallel lamination during neurogenesis

      Liu, Y., Bergmann, T., Mori, Yuki, Peralvo Vidal, Juan Miguel, Pihl, M., Vasistha, Navneet A, Thomsen, Preben Dybdahl, Seemann, Ernst Stefan, Gorodkin, Jan, Hyttel, P., Khodosevich, Konstantin, Witter, M. P. & Hall, Vanessa Jane, 2021, In: Frontiers in Neuroanatomy. 15, 19 p., 663667.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      PIAS2-mediated blockade of IFN-β signaling: a basis for sporadic Parkinson disease dementia

      Magalhaes, J., Tresse, E., Ejlerskov, P., Hu, E., Liu, Y., Marin, A., Montalant, A., Satriano, L., Rundsten, C. F., Carlsen, E. M. M., Rydbirk, R., Sharifi-Zarchi, A., Andersen, J. B., Aznar, S., Brudek, T., Khodosevich, K., Prinz, M., Perrier, J. F. M., Sharma, M., Gasser, T. & 1 others, Issazadeh-Navikas, Shohreh, 2021, In: Molecular Psychiatry. 26, p. 6083–6099 17 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Selective vulnerability of supragranular layer neurons in schizophrenia

      Batiuk, M. Y., Tyler, T., Mei, S., Rydbirk, Rasmus, Petukhov, V., Sedmak, D., Frank, E., Feher, V., Habek, N., Hu, Q., Igolkina, A., Roszik, L., Pfisterer, U., Petanjek, Z., Adorjan, I., Kharchenko, P. V. & Khodosevich, Konstantin, 2021, (bioRxiv).

      Research output: Working paper › Preprint › Research

    20. Published

      The impact of (ab)normal maternal environment on cortical development

      Vasistha, Navneet A & Khodosevich, Konstantin, 2021, In: Progress in Neurobiology. 202, 22 p., 102054.

      Research output: Contribution to journal › Review › Research › peer-review

    21. 2020
    22. Published

      A community-based transcriptomics classification and nomenclature of neocortical cell types

      Yuste, R., Hawrylycz, M., Aalling, N., Aguilar-valles, A., Arendt, D., Arnedillo, R. A., Ascoli, G. A., Bielza, C., Bokharaie, V., Bergmann, T. B., Bystron, I., Capogna, M., Chang, Y., Clemens, A., De Kock, C. P. J., Defelipe, J., Dos Santos, S. E., Dunville, K., Feldmeyer, D., Fiáth, R. & 53 others, Fishell, G. J., Foggetti, A., Gao, X., Ghaderi, P., Goriounova, N. A., Güntürkün, O., Hagihara, K., Hall, Vanessa Jane, Helmstaedter, M., Herculano, S., Hilscher, M. M., Hirase, Hajime, Hjerling-leffler, J., Hodge, R., Huang, J., Huda, R., Khodosevich, Konstantin, Kiehn, Ole, Koch, H., Kuebler, E. S., Kühnemund, M., Larrañaga, P., Lelieveldt, B., Louth, E. L., Lui, J. H., Mansvelder, H. D., Marin, O., Martinez-trujillo, J., Moradi Chameh, H., Nath, A., Nedergaard, M., Němec, P., Ofer, N., Pfisterer, U. G., Pontes, S., Redmond, W., Rossier, J., Sanes, J. R., Scheuermann, R., Serrano-saiz, E., Steiger, J. F., Somogyi, P., Tamás, G., Tolias, A. S., Tosches, M. A., García, M. T., Vieira, H. M., Wozny, C., Wuttke, T. V., Yong, L., Yuan, J., Zeng, H. & Lein, E., 2020, In: Nature Neuroscience. 23, p. 1456-1468 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Bayesian segmentation of spatially resolved transcriptomics data

      Petukhov, V., Soldatov, R. A., Khodosevich, Konstantin & Kharchenko, P. V., 2020, Cold Spring Harbor Laboratory, (bioRxiv).

      Research output: Working paper › Preprint › Research

    24. Published

      Complex IV subunit isoform COX6A2 protects fast-spiking interneurons from oxidative stress and supports their function

      Sanz-Morello, B., Pfisterer, U., Hansen, Nikolaj Winther, Demharter, S., Thakur, A., Fujii, K., Levitskii, S. A., Montalant, A., Korshunova, Irina, Mammen, P. P., Kamenski, P., Noguchi, S., Aldana, Blanca, Hougaard, Karin Sørig, Perrier, Jean-Francois Marie & Khodosevich, Konstantin, 2020, In: The EMBO Journal. 39, 18, p. 1-21 e105759.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Genetic modification increases the survival and the neuroregenerative properties of transplanted neural stem cells

      Korshunova, Irina, Rhein, S., vsz834, vsz834, Stölting, I., Pfisterer, U., Barta, A., Dmytriyeva, O., Kirkeby, Agnete, Schwaninger, M. & Khodosevich, Konstantin, 2020, In: JCI insight. 5, 4, p. 1-19 e126268.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Maternal inflammation has a profound effect on cortical interneuron development in a stage and subtype-specific manner

      Vasistha, Navneet A, Pardo-Navarro, M., Gasthaus, J., Weijers, D., Müller, M. K., vsz834, vsz834, Malwade, S., Korshunova, Irina, Pfisterer, U., von Engelhardt, J., Hougaard, Karin Sørig & Khodosevich, Konstantin, 2020, In: Molecular Psychiatry. 25, p. 2313-2329

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. 2019
    28. Published

      Joint analysis of heterogeneous single-cell RNA-seq dataset collections

      Barkas, N., Petukhov, V., Nikolaeva, D., Lozinsky, Y., Demharter, S., Khodosevich, Konstantin & Kharchenko, P. V., Aug 2019, In: Nature Methods. 16, 8, p. 695-698

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Dynamic Changes in Ultrastructure of the Primary Cilium in Migrating Neuroblasts in the Postnatal Brain

      Matsumoto, M., Sawada, M., vsz834, vsz834, Herranz-pérez, V., Ogino, T., Bang Nguyen, H., Quynh Thai, T., Narita, K., Kumamoto, N., Ugawa, S., Saito, Y., Takeda, S., Kaneko, N., Khodosevich, Konstantin, Monyer, H., García-verdugo, J. M., Ohno, N. & Sawamoto, K., 2019, In: The Journal of Neuroscience. 39, 50, p. 9967-9988

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      GluA4-Targeted AAV Vectors Deliver Genes Selectively to Interneurons while Relying on the AAV Receptor for Entry

      Hartmann, J., Thalheimer, F. B., Höpfner, F., Kerzel, T., Khodosevich, Konstantin, vsz834, vsz834, Monyer, H., Diester, I., Büning, H., Carette, J. E., Fries, P. & Buchholz, C. J., 2019, In: Molecular Therapy - Methods & Clinical Development. 14, p. 252-260 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Neuroserpin expression during human brain development and in adult brain revealed by immunohistochemistry and single cell RNA sequencing

      Adorjan, I., Tyler, T., Bhaduri, A., Demharter, S., Finszter, C. K., Bako, M., Sebok, O. M., Nowakowski, T. J., Khodosevich, Konstantin, Møllgård, Kjeld, Kriegstein, A. R., Shi, L., Hoerder-Suabedissen, A., Ansorge, O. & Molnár, Z., 2019, In: Journal of Anatomy. 235, 3, p. 543-554 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 144897711