Bjarne Winther Kristensen

Bjarne Winther Kristensen

Clinical Professor


  1. 2024
  2. Published

    Homeostatic iron regulatory protein drives glioblastoma growth via tumor cell-intrinsic and sex-specific responses

    Troike, K. M., Wang, S. Z., Silver, D. J., Lee, J., Mulkearns-Hubert, E. E., Hajdari, N., Ghosh, P. K., Kay, K. E., Beilis, J. L., Mitchell, S. E., Bishop, C. W., Hong, E. S., Artomov, M., Hubert, C. G., Rajappa, P., Connor, J. R., Fox, P. L., Kristensen, Bjarne Winther & Lathia, J. D., 2024, In: Neuro-Oncology Advances. 6, 1, 15 p., vdad154.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    The importance of considering competing risks in recurrence analysis of intracranial meningioma

    Mirian, C., Jensen, L. R., Juratli, T. A., Maier, A. D., Torp, S. H., Shih, H. A., Morshed, R. A., Young, J. S., Magill, S. T., Bertero, L., Stummer, W., Spille, D. C., Brokinkel, B., Oya, S., Miyawaki, S., Saito, N., Proescholdt, M., Kuroi, Y., Gousias, K., Simon, M. & 57 others, Moliterno, J., Prat-Acin, R., Goutagny, S., Prabhu, V. C., Tsiang, J. T., Wach, J., Güresir, E., Yamamoto, J., Kim, Y. Z., Lee, J. H., Koshy, M., Perumal, K., Baskaya, M. K., Cannon, D. M., Shrieve, D. C., Suh, C. O., Chang, J. H., Kamenova, M., Straumann, S., Soleman, J., Eyüpoglu, I. Y., Catalan, T., Lui, A., Theodosopoulos, P. V., McDermott, M. W., Wang, F., Guo, F., Góes, P., de Paiva Neto, M. A., Jamshidi, A., Komotar, R., Ivan, M., Luther, E., Souhami, L., Guiot, M. C., Csonka, T., Endo, T., Barrett, O. C., Jensen, R., Gupta, T., Patel, A. J., Klisch, T. J., Kim, J. W., Maiuri, F., Barresi, V., Tabernero, M. D., Skyrman, S., Broechner, A., Bach, M. J., Law, Ian, Scheie, David, Kristensen, Bjarne Winther, Munch, Tina Nørgaard, Meling, T., Fugleholm, Kåre, Blanche, Paul Frédéric & Mathiesen, Tiit Illimar, 2024, In: Journal of Neuro-Oncology. p. 503–511 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2023
  5. Molecular diagnostic tools for the World Health Organization (WHO) 2021 classification of gliomas, glioneuronal and neuronal tumors; an EANO guideline

    Sahm, F., Brandner, S., Bertero, L., Capper, D., French, P. J., Figarella-Branger, D., Giangaspero, F., Haberler, C., Hegi, M. E., Kristensen, Bjarne Winther, Kurian, K. M., Preusser, M., Tops, B. B. J., van den Bent, M., Wick, W., Reifenberger, G. & Wesseling, P., 2 Jun 2023, (E-pub ahead of print) In: Neuro-Oncology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    A variability in response of osteoclasts to zoledronic acid is mediated by smoking-associated modification in the DNA methylome

    Tan, Q., Møller, A. M. J., Qiu, C., Madsen, J. S., Shen, H., Bechmann, T., Delaisse, J. M., Kristensen, Bjarne Winther, Deng, H. W., Karasik, D. & Søe, K., 2023, In: Clinical Epigenetics. 15, 1, 14 p., 42.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    D-2-hydroxyglutarate regulates human brain vascular endothelial cell proliferation and barrier function

    Cao, C., Zhang, L., Sorensen, M. D., Reifenberger, Guido, Kristensen, Bjarne Winther, McIntyre, T. M. & Lin, F., 2023, In: Journal of Neuropathology and Experimental Neurology. 82, 11, p. 921-933 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Differential expression of checkpoint markers in the normoxic and hypoxic microenvironment of glioblastomas

    Petterson, S. A., Sørensen, M. D., Burton, M., Thomassen, M., Kruse, T. A., Michaelsen, Signe Regner & Kristensen, Bjarne Winther, 2023, In: Brain Pathology. 33, 1, 14 p., e13111.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Gene expression analysis during progression of malignant meningioma compared to benign meningioma

    Maier, A. D., Meddis, Alessandra, Mirian, C., Haslund-Vinding, Jeppe Lohfert, Bartek, J., Krog, S. M., Nguyen, T. U. P., Areškevičiūtė, A., Melchior, L. C., Heegaard, Steffen, Kristensen, Bjarne Winther, Munch, Tina Nørgaard, Fugleholm, Kåre, Ziebell, M., Raleigh, D. R., Poulsen, F. R., Gerds, Thomas Alexander, Litman, Thomas, Scheie, David & Mathiesen, Tiit Illimar, 2023, In: Journal of Neurosurgery. 138, 5, p. 1-11 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Glioneuronal tumor with ATRX alteration, kinase fusion and anaplastic features (GTAKA): a molecularly distinct brain tumor type with recurrent NTRK gene fusions

    Bogumil, H., Sill, M., Schrimpf, D., Ismer, B., Blume, C., Rahmanzade, R., Hinz, F., Cherkezov, A., Banan, R., Friedel, D., Reuss, D. E., Selt, F., Ecker, J., Milde, T., Pajtler, K. W., Schittenhelm, J., Hench, J., Frank, S., Boldt, H. B., Kristensen, B. W. & 32 others, Scheie, David, Melchior, L. C., Olesen, V., Sehested, A., Boué, D. R., Abdullaev, Z., Satgunaseelan, L., Kurth, I., Seidlitz, A., White, C. L., Ng, H. K., Shi, Z. F., Haberler, C., Deckert, M., Timmer, M., Goldbrunner, R., Tauziède-Espariat, A., Varlet, P., Brandner, S., Alexandrescu, S., Snuderl, M., Aldape, K., Korshunov, A., Witt, O., Herold-Mende, C., Unterberg, A., Wick, W., Pfister, S. M., von Deimling, A., Jones, D. T. W., Sahm, F. & Sievers, P., 2023, In: Acta Neuropathologica. 145, p. 667–680

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Loss of cancer cell-derived ADAM15 alters the tumor microenvironment in colorectal tumors

    Puig Blasco, Laia, Piotrowski, Kris, Michaelsen, Signe Regner, Bager, Nicolai Stilling Schou, Areškevičiūtiė, A., Thorseth, M., Sun, X., Keller, U. A. D., Kristensen, Bjarne Winther, Madsen, D. H., Gnosa, S. P. & Kveiborg, Marie, 2023, In: International Journal of Cancer. 153, 12, p. 2068–2081 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Non-metabolic functions of phosphofructokinase-1 orchestrate tumor cellular invasion and genome maintenance under bevacizumab therapy

    Lim, Y. C., Jensen, K. E., Aguilar-Morante, D., Vardouli, L., Vitting-Seerup, K., Gimple, R. C., Wu, Q., Pedersen, H., Elbaek, K. J., Gromova, I., Ihnatko, R., Kristensen, Bjarne Winther, Petersen, J. K., Skjoth-Rasmussen, J., Flavahan, W., Rich, J. N. & Hamerlik, P., 2023, In: Neuro-Oncology. 25, 2, p. 248-260 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2022
  14. Published

    Expression of GDNF and its receptors in glioblastoma

    Ewald, J. D., Knudsen, A. M. & Kristensen, Bjarne Winther, 2022, In: Neuro-Oncology. 24, 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  15. Published

    Expression, prognostic significance and therapeutic implications of PD-L1 in gliomas

    Vimalathas, G. & Kristensen, Bjarne Winther, 2022, In: Neuropathology and Applied Neurobiology. 48, 1, 27 p., e12767.

    Research output: Contribution to journalReviewResearchpeer-review

  16. Published

    Implementation of TERT promoter mutations improve prognostication of the WHO classification in meningioma

    Mirian, C., Grell, K., Juratli, T. A., Sahm, F., Spiegl-Kreinecker, S., Peyre, M., Biczok, A., Tonn, J. C., Goutagny, S., Bertero, L., Maier, A. D., Jensen, L. R., Schackert, G., Broholm, H., Scheie, D., Cahill, D. P., Brastianos, P. K., Skjøth-Rasmussen, J., Fugleholm, K., Ziebell, M. & 3 others, Munch, Tina Nørgaard, Kristensen, Bjarne Winther & Mathiesen, Tiit Illimar, 2022, In: Neuropathology and Applied Neurobiology. 48, 3, 5 p., e12773.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Letter to the Editor. Copenhagen grading of meningioma

    Mathiesen, Tiit Illimar, Haslund-Vinding, Jeppe Lohfert, Skjøth, Jane, Poulsgaard, L., Fugleholm, Kåre, Mirian, C., Daniela Maier, A., Santarius, T., Rom Poulsen, F., Andrée Larsen, V., Kristensen, Bjarne Winther, Scheie, David, Law, Ian & Ziebell, M., 2022, In: Journal of Neurosurgery. 136, 5, p. 1506-1508 3 p.

    Research output: Contribution to journalLetterResearchpeer-review

  18. Published

    Proposal of a new grading system for meningioma resection: the Copenhagen Protocol

    Haslund-Vinding, Jeppe Lohfert, Skjøth, Jane, Poulsgaard, L., Fugleholm, Kåre, Larsen, Christian Mirian, Maier, A. D., Santarius, T., Poulsen, F. R., Meling, T., Bartek, J. J., Förander, P., Larsen, V. A., Kristensen, Bjarne Winther, Scheie, David, Law, Ian, Ziebell, M. & Mathiesen, Tiit Illimar, 2022, In: Acta Neurochirurgica. 164, p. 229-238

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Redefining germline predisposition in children with molecularly characterized ependymoma: a population-based 20-year cohort

    Foss-Skiftesvik, J., Stoltze, U. K., Hansen, Thomas van Overeem, Ahlborn, L. B., Sørensen, E., Ostrowski, Sisse Rye, Kullegaard, S. M. A., Laspiur, A. O., Melchior, L. C., Scheie, David, Kristensen, Bjarne Winther, Skjøth, Jane, Schmiegelow, Kjeld, Wadt, Karin Anna Wallentin & Mathiasen, René, 2022, In: Acta Neuropathologica Communications. 10, 123.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Somatostatin analogues in treatment-refractory meningioma: a systematic review with meta-analysis of individual patient data

    Jensen, L. R., Maier, A. D., Lomstein, A., Graillon, T., Hrachova, M., Bota, D., Ruiz-Patiño, A., Arrieta, O., Cardona, A. F., Rudà, R., Furtner, J., Roeckle, U., Clement, P., Preusser, M., Scheie, D., Broholm, H., Kristensen, B. W., Skjøth-Rasmussen, J., Ziebell, M., Munch, T. N. & 4 others, Fugleholm, Kåre, Walter, M. A., Mathiesen, Tiit Illimar & Mirian, C., 2022, In: Neurosurgical Review. 45, p. 3067-3081

    Research output: Contribution to journalReviewResearchpeer-review

  21. Published

    Surgical resection of glioblastomas induces pleiotrophin-mediated self-renewal of glioblastoma stem cells in recurrent tumors

    Knudsen, A. M., Halle, B., Cédile, O., Burton, M., Baun, C., Thisgaard, H., Anand, Atul, Hubert, C., Thomassen, M., Michaelsen, Signe Regner, Olsen, B. B., Dahlrot, R. H., Bjerkvig, R., Lathia, J. D. & Kristensen, Bjarne Winther, 2022, In: Neuro-Oncology. 24, 7, p. 1074-1087 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    The Epigenetic Regulator Jumonji Domain-Containing Protein 6 (JMJD6) Is Highly Expressed but Not Prognostic in IDH-Wildtype Glioblastoma Patients

    Rosager, A. M., Dahlrot, R. H., Sørensen, M. D., Bangsø, J. A., Hansen, S. & Kristensen, Bjarne Winther, 2022, In: Journal of Neuropathology and Experimental Neurology. 81, 1, p. 54-60 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Tumour-associated CD204+ microglia/macrophages accumulate in perivascular and perinecrotic niches and correlate with an interleukin-6-enriched inflammatory profile in glioblastoma

    Sorensen, M. D. & Kristensen, Bjarne Winther, 2022, In: Neuropathology and Applied Neurobiology. 48, 2, 23 p., 12772.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. 2021
  25. Altered lipid metabolism marks glioblastoma stem and non-stem cells in separate tumor niches

    Shakya, S., Gromovsky, A. D., Hale, J. S., Knudsen, A. M., Prager, B., Wallace, L. C., Penalva, L. O. F., Brown, H. A., Kristensen, Bjarne Winther, Rich, J. N., Lathia, J. D., Brown, J. M. & Hubert, C. G., Dec 2021, In: Acta neuropathologica communications. 9, 1, p. 101 101.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. 12th european congress of neuropathology welcome from the congress president

    Kristensen, Bjarne Winther, Aug 2021, In: Clinical Neuropathology. 40, 7, p. 215-216 2 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  27. The multi-target small-molecule inhibitor SB747651A shows in vitro and in vivo anticancer efficacy in glioblastomas

    Knudsen, A. M., Boldt, H. B., Jakobsen, E. V. & Kristensen, Bjarne Winther, 16 Mar 2021, In: Scientific Reports. 11, 1, p. 6066 6066.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Asymmetric cell division promotes therapeutic resistance in glioblastoma stem cells

    Hitomi, M., Chumakova, A. P., Silver, D. J., Knudsen, A. M., Pontius, W. D., Murphy, S., Anand, N., Kristensen, Bjarne Winther & Lathia, J. D., 8 Feb 2021, In: JCI Insight. 6, 3, e130510.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Targeted next-generation sequencing of adult gliomas for retrospective prognostic evaluation and up-front diagnostics

    Petersen, J. K., Boldt, H. B., Sørensen, M. D., Blach, S., Dahlrot, R. H., Hansen, S., Burton, M., Thomassen, M., Kruse, T., Poulsen, F. R., Andreasen, L., Hager, H., Ulhøi, B. P., Lukacova, S., Reifenberger, G. & Kristensen, Bjarne Winther, Feb 2021, In: Neuropathology and Applied Neurobiology. 47, 1, p. 108-126 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 245405291