Bjarne Winther Kristensen

Bjarne Winther Kristensen

Clinical Professor

Member of:

  • Pathology

ORCID: 0000-0002-6352-0826

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  1. 12th european congress of neuropathology welcome from the congress president

    Kristensen, Bjarne Winther, Aug 2021, In: Clinical Neuropathology. 40, 7, p. 215-216 2 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  2. 3-Nitropropionic acid neurotoxicity in hippocampal slice cultures: developmental and regional vulnerability and dependency on glucose

    Noer, H., Kristensen, Bjarne Winther, Noraberg, J., Zimmer, J. & Gramsbergen, J. B., Jul 2002, In: Experimental Neurology. 176, 1, p. 237-46 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. A 4-miRNA signature to predict survival in glioblastomas

    Hermansen, S. K., Sørensen, M. D., Hansen, A., Knudsen, S., Alvarado, A. G., Lathia, J. D. & Kristensen, Bjarne Winther, 2017, In: PLoS One. 12, 11, p. e0188090

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. A population-based study of high-grade gliomas and mutated isocitrate dehydrogenase 1

    Dahlrot, R. H., Kristensen, Bjarne Winther, Hjelmborg, J., Herrstedt, J. & Hansen, S., 2013, In: International Journal of Clinical and Experimental Pathology. 6, 1, p. 31-40 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. A population-based study of low-grade gliomas and mutated isocitrate dehydrogenase 1 (IDH1)

    Dahlrot, R. H., Kristensen, Bjarne Winther, Hjelmborg, J., Herrstedt, J. & Hansen, S., Sep 2013, In: Journal of Neuro-Oncology. 114, 3, p. 309-17 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    A variability in response of osteoclasts to zoledronic acid is mediated by smoking-associated modification in the DNA methylome

    Tan, Q., Møller, A. M. J., Qiu, C., Madsen, J. S., Shen, H., Bechmann, T., Delaisse, J. M., Kristensen, Bjarne Winther, Deng, H. W., Karasik, D. & Søe, K., 2023, In: Clinical Epigenetics. 15, 1, 14 p., 42.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion

    Schuster, A., Klein, E., Neirinckx, V., Knudsen, A. M., Fabian, C., Hau, A., Dieterle, M., Oudin, A., Nazarov, P. V., Golebiewska, A., Muller, A., Perez-Hernandez, D., Rodius, S., Dittmar, G., Bjerkvig, R., Herold-Mende, C., Klink, B., Kristensen, Bjarne Winther & Niclou, S. P., 11 Dec 2020, In: Nature Communications. 11, 1, p. 6366

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. APNG as a prognostic marker in patients with glioblastoma

    Fosmark, S., Hellwege, S., Dahlrot, R. H., Jensen, K. L., Derand, H., Lohse, J., Sørensen, M. D., Hansen, S. & Kristensen, Bjarne Winther, 2017, In: PLoS One. 12, 6, p. e0178693

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Aberrant neuronal differentiation is common in glioma but is associated neither with epileptic seizures nor with better survival

    Beier, C. P., Rasmussen, T., Dahlrot, R. H., Tenstad, H. B., Aarø, J. S., Sørensen, M. F., Heimisdóttir, S. B., Sørensen, M. D., Svenningsen, P., Riemenschneider, M. J., Beier, D. & Kristensen, Bjarne Winther, 8 Oct 2018, In: Scientific Reports. 8, 1, p. 14965

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Acute hypoxia induces upregulation of microRNA-210 expression in glioblastoma spheroids

    Rosenberg, T., Thomassen, M., Jensen, S. S., Larsen, M. J., Sørensen, K. P., Hermansen, S. K., Kruse, T. A. & Kristensen, Bjarne Winther, 2015, In: CNS oncology. 4, 1, p. 25-35 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Altered lipid metabolism marks glioblastoma stem and non-stem cells in separate tumor niches

    Shakya, S., Gromovsky, A. D., Hale, J. S., Knudsen, A. M., Prager, B., Wallace, L. C., Penalva, L. O. F., Brown, H. A., Kristensen, Bjarne Winther, Rich, J. N., Lathia, J. D., Brown, J. M. & Hubert, C. G., Dec 2021, In: Acta neuropathologica communications. 9, 1, p. 101 101.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Alternative lengthening of telomeres is the major telomere maintenance mechanism in astrocytoma with isocitrate dehydrogenase 1 mutation

    Ferreira, M. S. V., Sørensen, M. D., Pusch, S., Beier, D., Bouillon, A., Kristensen, Bjarne Winther, Brümmendorf, T. H., Beier, C. P. & Beier, F., Mar 2020, In: Journal of Neuro-Oncology. 147, 1, p. 1-14 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Asymmetric cell division promotes therapeutic resistance in glioblastoma stem cells

    Hitomi, M., Chumakova, A. P., Silver, D. J., Knudsen, A. M., Pontius, W. D., Murphy, S., Anand, N., Kristensen, Bjarne Winther & Lathia, J. D., 8 Feb 2021, In: JCI Insight. 6, 3, e130510.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    BCG Vaccination and Risk of Atopy

    Krause, Tyra Grove, Hviid, Anders Peter, Koch, A., Friborg, Jeppe Tang, Hjuler, Thomas, Wohlfahrt, J., Olsen, O. R., Kristensen, Bjarne Winther & Melbye, M., 26 Feb 2003, In: Journal of the American Medical Association. 289, 8, p. 1012-1015 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Biocompatibility of silicon-based arrays of electrodes coupled to organotypic hippocampal brain slice cultures

    Kristensen, Bjarne Winther, Noraberg, J., Thiébaud, P., Koudelka-Hep, M. & Zimmer, J., 30 Mar 2001, In: Brain Research. 896, 1-2, p. 1-17 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. CD133 identifies perivascular niches in grade II-IV astrocytomas

    Christensen, K., Schrøder, H. D. & Kristensen, Bjarne Winther, Nov 2008, In: Journal of Neuro-Oncology. 90, 2, p. 157-70 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. CD133+ niches and single cells in glioblastoma have different phenotypes

    Christensen, K., Schrøder, H. D. & Kristensen, Bjarne Winther, Aug 2011, In: Journal of Neuro-Oncology. 104, 1, p. 129-43 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Cardiac leiomyosarcoma, a case report

    Andersen, R. E., Kristensen, Bjarne Winther & Gill, S., 2013, In: International Journal of Clinical and Experimental Pathology. 6, 6, p. 1197-9 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Cell therapy centered on IL-1Ra is neuroprotective in experimental stroke

    Clausen, B. H., Lambertsen, K. L., Dagnæs-Hansen, F., Babcock, A. A., von Linstow, C. U., Meldgaard, M., Kristensen, Bjarne Winther, Deierborg, T. & Finsen, B., May 2016, In: Acta Neuropathologica. 131, 5, p. 775-91 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Characterization of the TNF and IL-1 systems in human brain and blood after ischemic stroke

    Clausen, B. H., Wirenfeldt, M., Høgedal, S. S., Frich, L. H., Nielsen, H. H., Schrøder, H. D., Østergaard, K., Finsen, B., Kristensen, Bjarne Winther & Lambertsen, K. L., 5 Jun 2020, In: Acta neuropathologica communications. 8, 1, p. 81

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Chemoresistance and chemotherapy targeting stem-like cells in malignant glioma

    Sørensen, M. D., Fosmark, S., Hellwege, S., Beier, D., Kristensen, Bjarne Winther & Beier, C. P., 2015, In: Advances in Experimental Medicine and Biology. 853, p. 111-38 28 p.

    Research output: Contribution to journal › Review › Research › peer-review

  22. Chordoid meningiomas can be sub-stratified into prognostically distinct DNA methylation classes and are enriched for heterozygous deletions of chromosomal arm 2p

    Sievers, P., Stichel, D., Hielscher, T., Schrimpf, D., Reinhardt, A., Wefers, A. K., Reuss, D., Jones, D. T. W., Bewerunge-Hudler, M., Hartmann, C., Baumgarten, P., Wirsching, H-G., Winther-Kristensen, B., Brokinkel, B., Ketter, R., Idoate Gastearena, M. A., Lamszus, K., Seiz-Rosenhagen, M., Mawrin, C., Harter, P. N. & 11 others, Felsberg, J., Hänggi, D., Herold-Mende, C., Berghoff, A. S., Weller, M., Pfister, S. M., Wick, W., Reifenberger, G., Preusser, M., von Deimling, A. & Sahm, F., Dec 2018, In: Acta Neuropathologica. 136, 6, p. 975-978 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Clinical value of CD133 and nestin in patients with glioma: a population-based study

    Dahlrot, R. H., Hansen, S., Jensen, S. S., Schrøder, H. D., Hjelmborg, J. & Kristensen, Bjarne Winther, 2014, In: International Journal of Clinical and Experimental Pathology. 7, 7, p. 3739-51 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Colchicine induces apoptosis in organotypic hippocampal slice cultures

    Kristensen, Bjarne Winther, Noer, H., Gramsbergen, J. B., Zimmer, J. & Noraberg, J., 28 Feb 2003, In: Brain Research. 964, 2, p. 264-78 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Comparison of 5-aminolevulinic acid and sodium fluorescein for intraoperative tumor visualization in patients with high-grade gliomas: a single-center retrospective study

    Hansen, R. W., Pedersen, C. B., Halle, B., Korshoej, A. R., Schulz, M. K., Kristensen, Bjarne Winther & Poulsen, F. R., 4 Oct 2019, (E-pub ahead of print) In: Journal of Neurosurgery. p. 1-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Comparison of excitotoxic profiles of ATPA, AMPA, KA and NMDA in organotypic hippocampal slice cultures

    Kristensen, Bjarne Winther, Noraberg, J. & Zimmer, J., 26 Oct 2001, In: Brain Research. 917, 1, p. 21-44 24 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Conditional ablation of myeloid TNF increases lesion volume after experimental stroke in mice, possibly via altered ERK1/2 signaling

    Clausen, B. H., Degn, M., Sivasaravanaparan, M., Fogtmann, T., Andersen, M. G., Trojanowsky, M. D., Gao, H., Hvidsten, S., Baun, C., Deierborg, T., Finsen, B., Kristensen, Bjarne Winther, Bak, S. T., Meyer, M., Lee, J., Nedospasov, S. A., Brambilla, R. & Lambertsen, K. L., 7 Jul 2016, In: Scientific Reports. 6, p. 29291

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Convection-enhanced delivery of an anti-miR is well-tolerated, preserves anti-miR stability and causes efficient target de-repression: a proof of concept

    Halle, B., Marcusson, E. G., Aaberg-Jessen, C., Jensen, S. S., Meyer, M., Schulz, M. K., Andersen, C. & Kristensen, Bjarne Winther, Jan 2016, In: Journal of Neuro-Oncology. 126, 1, p. 47-55 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Coupling of Organotypic Brain Slice Cultures to Silicon-Based Arrays of Electrodes

    Jahnsen, Henrik, Kristensen, Bjarne Winther, Thiébaud, P., Noraberg, J., Jakobsen, B., Bove, M., Martinoa, S., Koudelka-Hep, M., Grattarola, M. & Zimmer, J., 1999, In: Methods. 18, 2, p. 160-172

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. D-2-Hydroxyglutarate Is an Intercellular Mediator in IDH-Mutant Gliomas Inhibiting Complement and T Cells

    Zhang, L., Sorensen, M. D., Kristensen, Bjarne Winther, Reifenberger, G., McIntyre, T. M. & Lin, F., 1 Nov 2018, In: Clinical Cancer Research. 24, 21, p. 5381-5391 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    D-2-hydroxyglutarate regulates human brain vascular endothelial cell proliferation and barrier function

    Cao, C., Zhang, L., Sorensen, M. D., Reifenberger, Guido, Kristensen, Bjarne Winther, McIntyre, T. M. & Lin, F., 2023, In: Journal of Neuropathology and Experimental Neurology. 82, 11, p. 921-933 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Differential expression of checkpoint markers in the normoxic and hypoxic microenvironment of glioblastomas

    Petterson, S. A., Sørensen, M. D., Burton, M., Thomassen, M., Kruse, T. A., Michaelsen, Signe Regner & Kristensen, Bjarne Winther, 2023, In: Brain Pathology. 33, 1, 14 p., e13111.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Do we really know who has an MGMT methylated glioma? Results of an international survey regarding use of MGMT analyses for glioma

    Malmström, A., Łysiak, M., Kristensen, Bjarne Winther, Hovey, E., Henriksson, R. & Söderkvist, P., Jan 2020, In: Neuro-Oncology Practice. 7, 1, p. 68-76 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Drug Repurposing Screen Reveals Glioblastoma Cell Line Susceptibility to Statins

    Harwood, Dylan Scott Lykke, Michaelsen, Signe Regner, Mundt, F. & Kristensen, Bjarne Winther, 2021, In: Neuro-Oncology. 23, S6, p. 77-78 2 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  35. Dual time-point FDG PET/CT and FDG uptake and related enzymes in lymphadenopathies: preliminary results

    Christlieb, S. B., Strandholdt, C. N., Olsen, B. B., Mylam, K. J., Larsen, T. S., Nielsen, A. L., Rohde, M., Gerke, O., Olsen, K. E., Møller, M. B., Kristensen, Bjarne Winther, Abildgaard, N., Alavi, A. & Høilund-Carlsen, P. F., Sep 2016, In: European Journal of Nuclear Medicine and Molecular Imaging. 43, 10, p. 1824-36 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Effects of chemotherapeutics on organotypic corticostriatal slice cultures identified by a panel of fluorescent and immunohistochemical markers

    Nørregaard, A., Jensen, S. S., Kolenda, J., Aaberg-Jessen, C., Christensen, K. G., Jensen, P. H., Schrøder, H. D. & Kristensen, Bjarne Winther, Jul 2012, In: Neurotoxicity Research. 22, 1, p. 43-58 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Effects of the lysosomal destabilizing drug siramesine on glioblastoma in vitro and in vivo

    Jensen, S. S., Petterson, S. A., Halle, B., Aaberg-Jessen, C. & Kristensen, Bjarne Winther, 7 Mar 2017, In: BMC Cancer. 17, 1, p. 178

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Endoscopic vs. microscopic transsphenoidal pituitary surgery: a single centre study

    Møller, M. W., Andersen, M. S., Glintborg, D., Pedersen, C. B., Halle, B., Kristensen, Bjarne Winther & Poulsen, F. R., 14 Dec 2020, In: Scientific Reports. 10, 1, p. 21942

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Establishment and Characterization of a Tumor Stem Cell-Based Glioblastoma Invasion Model

    Jensen, S. S., Meyer, M., Petterson, S. A., Halle, B., Rosager, A. M., Aaberg-Jessen, C., Thomassen, M., Burton, M., Kruse, T. A. & Kristensen, Bjarne Winther, 2016, In: PLoS One. 11, 7, p. e0159746

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Estimation of Tumor Volumes by 11C-MeAIB and 18F-FDG PET in an Orthotopic Glioblastoma Rat Model

    Halle, B., Thisgaard, H., Hvidsten, S., Dam, J. H., Aaberg-Jessen, C., Thykjær, A. S., Høilund-Carlsen, P. F., Schulz, M. K., Andersen, C. & Kristensen, Bjarne Winther, Oct 2015, In: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 56, 10, p. 1562-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Evaluation of the proliferation marker Ki-67 in gliomas: Interobserver variability and digital quantification

    Nielsen, L. A. G., Bangsø, J. A., Lindahl, K. H., Dahlrot, R. H., Hjelmborg, J. V. B., Hansen, S. & Kristensen, Bjarne Winther, 9 Jun 2018, In: Diagnostic Pathology. 13, 1, p. 38

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Excitatory amino acid neurotoxicity and modulation of glutamate receptor expression in organotypic brain slice cultures

    Zimmer, J., Kristensen, Bjarne Winther, Jakobsen, B. & Noraberg, J., 2000, In: Amino Acids. 19, 1, p. 7-21 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Excitotoxic effects of non-NMDA receptor agonists in organotypic corticostriatal slice cultures

    Kristensen, Bjarne Winther, Noraberg, J., Jakobsen, B., Gramsbergen, J. B., Ebert, B. & Zimmer, J., 11 Sep 1999, In: Brain Research. 841, 1-2, p. 143-59 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Expression Profiling of Primary and Recurrent Glioblastomas Reveals a Reduced Level of Pentraxin 3 in Recurrent Glioblastomas

    Petterson, S. A., Sørensen, M. D. & Kristensen, Bjarne Winther, 1 Sep 2020, In: Journal of Neuropathology and Experimental Neurology. 79, 9, p. 975-985 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Expression and Prognostic Value of Oct-4 in Astrocytic Brain Tumors

    Krogh Petersen, J., Jensen, P., Dahl Sørensen, M. & Kristensen, Bjarne Winther, 2016, In: PLoS One. 11, 12, p. e0169129

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Expression and Prognostic Value of the Immune Checkpoints Galectin-9 and PD-L1 in Glioblastomas

    Knudsen, A. M., Rudkjøbing, S. J., Sørensen, M. D., Dahlrot, R. H. & Kristensen, Bjarne Winther, 2021, In: Journal of Neuropathology and Experimental Neurology. 80, 6, p. 541-551 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Expression and prognostic impact of matrix metalloproteinase-2 (MMP-2) in astrocytomas

    Ramachandran, R. K., Sørensen, M. D., Aaberg-Jessen, C., Hermansen, S. K. & Kristensen, Bjarne Winther, 2017, In: PLoS One. 12, 2, p. e0172234

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Expression and prognostic value of JAM-A in gliomas

    Rosager, A. M., Sørensen, M. D., Dahlrot, R. H., Boldt, H. B., Hansen, S., Lathia, J. D. & Kristensen, Bjarne Winther, Oct 2017, In: Journal of Neuro-Oncology. 135, 1, p. 107-117 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Expression and prognostic value of the WEE1 kinase in gliomas

    Music, D., Dahlrot, R. H., Hermansen, S. K., Hjelmborg, J., de Stricker, K., Hansen, S. & Kristensen, Bjarne Winther, Apr 2016, In: Journal of Neuro-Oncology. 127, 2, p. 381-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Expression and prognostic value of the transcription factors EGR1 and EGR3 in gliomas

    Knudsen, A. M., Eilertsen, I., Kielland, S., Pedersen, M. W., Sørensen, M. D., Dahlrot, R. H., Boldt, H. B., Munthe, S., Poulsen, F. R. & Kristensen, Bjarne Winther, 9 Jun 2020, In: Scientific Reports. 10, 1, p. 9285

    Research output: Contribution to journal › Journal article › Research › peer-review

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