Sachin Pundhir

Sachin Pundhir

Senior Researcher

ORCID: 0000-0001-9047-7280

Publication year:
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1 - 24 out of 24Page size: 50
  1. 2023
  2. Published

    TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression

    Heyes, E., Wilhelmson, Anna, Wenzel, Anne, Manhart, G., Eder, T., Schuster, Mikkel Bruhn, Rzepa, E., Pundhir, Sachin, D’Altri, T., Frank, Anne-Katrine, Gentil, C., Woessmann, J., Schoof, E. M., Meggendorfer, M., Schwaller, J., Haferlach, T., Grebien, F. & Porse, Bo Torben, 2023, In: Nature Communications. 14, 18 p., 6185.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    The histone demethylase KDM5C functions as a tumor suppressor in AML by repression of bivalently marked immature genes

    Trempenau, M. L., Schuster, Mikkel Bruhn, Pundhir, Sachin, Araújo Pereira, Mafalda, Kalvisa, A., Tapia, Marta Cecylia, Su, Jinyu, Ge, Y., de Boer, Bauke, Balhuizen, Alexander, Bagger, F. O., Shliaha, P., Sroczynska, P., Walfridsson, J., Grønbæk, Kirsten, Theilgaard-Mønch, Kim, Jensen, O. N., Helin, K. & Porse, Bo Torben, 2023, In: Leukemia. 37, 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    The impact of SWI/SNF and NuRD inactivation on gene expression is tightly coupled with levels of RNA polymerase II occupancy at promoters

    Pundhir, Sachin, Su, Jinyu, Tapia, Marta Cecylia, Hansen, A. M., Haile, James Seymour, Hansen, K. & Porse, Bo Torben, 2023, In: Genome Research. 33, 3, p. 332-345 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. 2022
  6. Published

    H3K9 dimethylation safeguards cancer cells against activation of the interferon pathway

    Hansen, A. M., Ge, Y., Schuster, Mikkel Bruhn, Pundhir, Sachin, Jakobsen, J. S., Kalvisa, A., Tapia, Marta Cecylia, Gordon, Sandra, Ambri, F., Bagger, F. O., Pandey, D., Helin, K. & Porse, Bo Torben, 2022, In: Science Advances. 8, 11, eabf8627.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    PTBP1 promotes hematopoietic stem cell maintenance and red blood cell development by ensuring sufficient availability of ribosomal constituents

    Rehn, M., Wenzel, Anne, Frank, Anne-Katrine, Schuster, Mikkel Bruhn, Pundhir, Sachin, Jørgensen, N., Vitting-Seerup, K., Ge, Y., Jendholm, J., Michaut, Magali, Schoof, E. M., Jensen, T. L., Rapin, N., Sapio, R. T., Andersen, Kasper Langebjerg, Lund, Anders H., Solimena, M., Holzenberger, M., Pestov, D. G. & Porse, Bo Torben, 2022, In: Cell Reports. 39, 6, 28 p., 110793.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Transcription factor-driven coordination of cell cycle exit and lineage-specification in vivo during granulocytic differentiation: In memoriam Professor Niels Borregaard

    Theilgaard-Mønch, Kim, Pundhir, Sachin, Reckzeh, K., Su, Jinyu, Tapia, Marta Cecylia, Furtwängler, Benjamin, Jendholm, J., Jakobsen, J. S., Hasemann, M. S., Knudsen, K. J., Cowland, J. B., Fossum, A., Schoof, E., Schuster, Mikkel Bruhn & Porse, Bo Torben, 2022, In: Nature Communications. 13, 1, 17 p., 3595.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. 2021
  10. Published

    The ASXL1-G643W variant accelerates the development of CEBPA mutant acute myeloid leukemia

    D'Altri, T., Wilhelmson, Anna, Schuster, Mikkel Bruhn, Wenzel, Anne, Kalvisa, A., Pundhir, Sachin, Hansen, A. M. & Porse, Bo Torben, 2021, In: Haematologica. 106, 4, p. 1000-1007 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. 2020
  12. Published

    Ancestrally Duplicated Conserved Noncoding Element Suggests Dual Regulatory Roles of HOTAIR in cis and trans

    Nepal, C., Taranta, A., Hadzhiev, Y., Pundhir, Sachin, Mydel, P., Lenhard, B., Müller, F. & Andersen, Jesper Bøje, 2020, In: iScience. 23, 4, p. 1-27 UNSP 101008.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. 2019
  14. Published

    Epigenetic and Transcriptomic Characterization of Pure Adipocyte Fractions From Obese Pigs Identifies Candidate Pathways Controlling Metabolism

    Jacobsen, M. J., Havgaard, Jakob Hull, Anthon, Christian, Mentzel, Caroline M. Junker, Cirera, Susanna, Krogh, P. M., Pundhir, Sachin, Karlskov-Mortensen, Peter, Bruun, C. S., Lesnik, P., Guerin, M., Gorodkin, Jan, Jørgensen, Claus Bøttcher, Fredholm, Merete & Barrès, Romain, 2019, In: Frontiers in Genetics. 10, 13 p., 1268.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Mutant CEBPA directly drives the expression of the targetable tumor-promoting factor CD73 in AML

    Jakobsen, J. S., Laursen, L. G., Schuster, Mikkel Bruhn, Pundhir, Sachin, Schoof, E., Ge, Y., d'Altri, T., Vitting-Seerup, K., Rapin, N., Gentil, C., Jendholm, J., Theilgaard-Mønch, Kim, Reckzeh, K., Bullinger, L., Döhner, K., Hokland, P., Fitzgibbon, J. & Porse, Bo Torben, 2019, In: Science Advances. 5, 7, p. 1-16 16 p., eaaw4304.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    The splicing factor RBM25 controls MYC activity in acute myeloid leukemia

    Ge, Y., Schuster, Mikkel Bruhn, Pundhir, Sachin, Rapin, N., Bagger, F. O., Sidiropoulos, N., Hashem, N. & Porse, Bo Torben, 2019, In: Nature Communications. 10, 1, p. 1-14 14 p., 172.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. 2018
  18. Published

    Differences in Cell Cycle Status Underlie Transcriptional Heterogeneity in the HSC Compartment

    Lauridsen, F. K., Jensen, T. L., Rapin, N., Aslan, D., Wilhelmson, Anna, Pundhir, Sachin, Rehn, M., Paul, F., Giladi, A., Hasemann, M. S., Serup, Palle, Amit, I. & Porse, Bo Torben, 2018, In: Cell Reports. 24, 3, p. 766-780 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Enhancer and Transcription Factor Dynamics during Myeloid Differentiation Reveal an Early Differentiation Block in Cebpa null Progenitors

    Pundhir, Sachin, Bratt Lauridsen, F. K., Schuster, Mikkel Bruhn, Jakobsen, J. S., Ge, Y., Schoof, E. M., Rapin, N. P. J., Waage, J., Hasemann, M. S. & Porse, Bo Torben, 2018, In: Cell Reports. 23, 9, p. 2744-2757 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    HOTAIR ancient sequence suggests regulatory roles both in cis and trans

    Nepal, C., Hadzheiv, Y., Pundhir, Sachin, Mydel, P., Lenhard, B., Mueller, F. & Andersen, J., 2018

    Research output: Other contribution › Research

  21. 2016
  22. Published

    Adipocyte gene expression and DNA methylation patterns differ significantly between lean and obese pigs

    Jacobsen, M. J., Havgaard, Jakob Hull, Mentzel, Caroline M. Junker, Sørensen, P. M., Pundhir, Sachin, Anthon, Christian, Karlskov-Mortensen, Peter, Bruun, Camilla Vibeke Sichlau, Cirera, Susanna, Gorodkin, Jan, Jørgensen, Claus Bøttcher, Barrès, Romain & Fredholm, Merete, 9 Nov 2016, In: Journal of Animal Science. 94, Supplement 4, p. 46-47 2 p., P2019.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  23. Published

    BloodSpot: a database of gene expression profiles and transcriptional programs for healthy and malignant haematopoiesis

    Bagger, F. O., Sasivarevic, D., Hadi Sohi, S., Laursen, L. G., Pundhir, Sachin, Sønderby, C. K., Winther, Ole, Rapin, N. & Porse, Bo Torben, 4 Jan 2016, In: Nucleic Acids Research. 44, D1, p. D917-24 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Peak-valley-peak pattern of histone modifications delineates active regulatory elements and their directionality

    Pundhir, Sachin, Bagger, F. O., Lauridsen, F. K. B., Rapin, N. P. J. & Porse, Bo Torben, 2016, In: Nucleic Acids Research. 44, 9, p. 4037-4051 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. 2015
  26. Published

    Differential and coherent processing patterns from small RNAs

    Pundhir, Sachin & Gorodkin, Jan, 13 Jul 2015, In: Scientific Reports. 5, 16 p., 12062.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Emerging applications of read profiles towards the functional annotation of the genome

    Pundhir, Sachin, Poirazi, P. & Gorodkin, Jan, 19 May 2015, In: Frontiers in Genetics. 6, 11 p., 188.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. 2014
  29. Published

    Spatially conserved regulatory elements identified within human and mouse Cd247 gene using high-throughput sequencing data from the ENCODE project.

    Pundhir, Sachin, Hannibal, T. D., Bang-Berthelsen, C. H., Wegener, A. K., Pociot, Flemming, Holmberg, D. I. & Gorodkin, Jan, 2 May 2014, In: Gene. 545, 1, p. 80-87 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Structured RNAs and synteny regions in the pig genome

    Anthon, Christian, Tafer, H., Havgaard, Jakob Hull, Thomsen, B., Hedegaard, J., Seemann, Ernst Stefan, Pundhir, Sachin, Kehr, S., Bartschat, S., Nielsen, M., Nielsen, R. O., Fredholm, Merete, Stadler, P. F. & Gorodkin, Jan, 2014, In: BMC Genomics. 15, 27 p., 459.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. 2012
  32. Published

    DeepBlockAlign: a tool for aligning RNA-seq profiles of read block patterns

    Langenberger, D., Pundhir, Sachin, Ekstrøm, Claus Thorn, Stadler, P. F., Hoffmann, S. & Gorodkin, Jan, 2012, In: Bioinformatics. 28, 1, p. 17-24 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. 2011

  34. SSPred: a prediction server based on SVM for the identification and classification of protein involved in bacterial secretion systems.

    Pundhir, Sachin & Kumar, A., 2011, In: Bioinformation. 6, 10, p. 380-382 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. 2008

  36. PredictBias: a server for the identification of genomic and pathogenicity islands in prokaryotes

    Pundhir, Sachin & Kumar, A., 2008, In: In Silico Biology. 8, 3-4, p. 223-234 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

ID: 21221836