Joachim Lütken Weischenfeldt

Joachim Lütken Weischenfeldt

Group leader, Clinical Professor

Member of:

    ORCID: 0000-0002-3917-5524

    Publication year:
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    1 - 25 out of 68Page size: 25
    1. 2024
    2. Published

      Loss of Upk1a and Upk1b expression is linked to stage progression in urothelial carcinoma of the bladder

      Kaczmarek, K., Plage, H., Furlano, K., Hofbauer, S., Weinberger, S., Ralla, B., Franz, A., Fendler, A., de Martino, M., Roßner, F., Schallenberg, S., Elezkurtaj, S., Kluth, M., Lennartz, M., Blessin, N. C., Marx, A. H., Samtleben, H., Fisch, M., Rink, M., Slojewski, M. & 12 others, Ecke, T., Hallmann, S., Koch, S., Adamini, N., Minner, S., Simon, R., Sauter, G., Weischenfeldt, Joachim Lütken, Klatte, T., Schlomm, T., Horst, D. & Zecha, H., 2024, In: International Urology and Nephrology. 56, p. 499-508 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Accepted/In press

      CEA (CEACAM5) expression is common in muscle-invasive urothelial carcinoma of the bladder but unrelated to the disease course

      Plage, H., Furlano, K., Neymeyer, J., Weinberger, S., Gerdes, B., Hubatsch, M., Ralla, B., Franz, A., Fendler, A., de Martino, M., Roßner, F., Schallenberg, S., Elezkurtaj, S., Kluth, M., Lennartz, M., Blessin, N. C., Marx, A. H., Samtleben, H., Fisch, M., Rink, M. & 14 others, Kaczmarek, K., Ecke, T., Hallmann, S., Koch, S., Adamini, N., Minner, S., Simon, R., Sauter, G., Weischenfeldt, Joachim Lütken, Klatte, T., Schlomm, T., Horst, D., Zecha, H. & Slojewski, M., 2024, (Accepted/In press) In: BJUI Compass.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. 2023
    5. Published

      Epithelial specific splicing regulator proteins as emerging oncogenes in aggressive prostate cancer

      Advani, R., Luzzi, S., Scott, E., Dalgliesh, C., Weischenfeldt, Joachim Lütken, Munkley, J. & Elliott, D. J., 2023, In: Oncogene. 42, p. 3161-3168 8 p.

      Research output: Contribution to journal › Review › Research › peer-review

    6. Published

      A polygenic two-hit hypothesis for prostate cancer

      Houlahan, K. E., Livingstone, J., Fox, N. S., Kurganovs, N., Zhu, H., Sietsma Penington, J., Jung, C-H., Yamaguchi, T. N., Heisler, L. E., Jovelin, R., Costello, A. J., Pope, B. J., Kishan, A. U., Corcoran, N. M., Bristow, R. G., Waszak, S. M., Weischenfeldt, J., He, H. H., Hung, R. J., Hovens, C. M. & 1 others, Boutros, P. C., 2023, In: Journal of the National Cancer Institute. 115, 4, p. 468-472 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Frequency and Functional Characterization of RUNX1 Germline Variants in Myeloid Neoplasms

      Nitschke, N. J., Almosailleakh, M., Niu, Yiyuan, Hansen, Jakob Werner, Raaschou-Jensen, K., Jespersen, Jakob Schmidt, Severinsen, M. T., Roug, A. S., Frödin, Morten, Weischenfeldt, Joachim Lütken, Andersen, M. K. & Grønbæk, Kirsten, 2023, In: Human Mutation. 2023, 11 p., 4738660.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      The Neurogenome study: Comprehensive molecular profiling to optimize treatment for Danish glioblastoma patients

      Nørøxe, D. S., Maarup, S., Fougner, Vincent Nicolay, Muhic, A., Møller, Søren, Urup, T., Lü, Maya Jeje Schuang, Weischenfeldt, Joachim Lütken, Hansen, Adam Espe, Skovgaard Poulsen, H., Lassen, Ulrik Niels & Hasselbalch, B., 2023, In: Neuro-Oncology Advances. 5, 1, 8 p., vdad137.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Hunting for the elusive target antigen in gestational alloimmune liver disease (GALD)

      Rieneck, K., Rasmussen, K. K., Schoof, E. M., Clausen, F. B., Holze, H., Bergholt, Thomas, Jørgensen, M. H., Christensen, Vibeke Brix, Almaas, R., Jordal, P. L., Locard-Paulet, Marie, Runager, K., Nielsen, L. K., Schlotmann, Balthasar Clemens, Weischenfeldt, Joachim Lütken, Jensen, Lars Juhl & Dziegiel, Morten Hanefeld, 2023, In: PLoS ONE. 18, 10, 25 p., e0286432.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      When 3D genome changes cause disease: the impact of structural variations in congenital disease and cancer

      Weischenfeldt, Joachim Lütken & Ibrahim, D. M., 2023, In: Current Opinion in Genetics and Development. 80, 102048.

      Research output: Contribution to journal › Review › Research › peer-review

    11. 2022
    12. Published

      Rare Germline Variants Are Associated with Rapid Biochemical Recurrence After Radical Prostate Cancer Treatment: A Pan Prostate Cancer Group Study

      Burns, D., Anokian, E., Saunders, E. J., Bristow, R. G., Fraser, M., Reimand, J., Schlomm, T., Sauter, G., Brors, B., Korbel, J., Weischenfeldt, J., Waszak, S. M., Corcoran, N. M., Jung, C. H., Pope, B. J., Hovens, C. M., Cancel-Tassin, G., Cussenot, O., Loda, M., Sander, C. & 16 others, Hayes, V. M., Dalsgaard Sorensen, K., Lu, Y. J., Hamdy, F. C., Foster, C. S., Gnanapragasam, V., Butler, A., Lynch, A. G., Massie, C. E., Woodcock, D. J., Cooper, C. S., Wedge, D. C., Brewer, D. S., Kote-Jarai, Z., Eeles, R. A. & CR-UK/Prostate Cancer UK, ICGC, The PPCG, C. C. U. I. T. P., 2022, In: European Urology. 82, 2, p. 201-211 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Structural variations in cancer and the 3D genome

      Dubois, F., Sidiropoulos, N., Weischenfeldt, Joachim Lütken & Beroukhim, R., 2022, In: Nature Reviews Cancer. 22, p. 533-546

      Research output: Contribution to journal › Review › Research › peer-review

    14. Published

      Implementing targeted therapies in the treatment of glioblastoma: Previous shortcomings, future promises, and a multimodal strategy recommendation

      Fougner, V., Hasselbalch, B., Lassen, Ulrik Niels, Weischenfeldt, Joachim Lütken, Poulsen, H. S. & Urup, T., 2022, In: Neuro-Oncology Advances. 4, 1, vdac157.

      Research output: Contribution to journal › Review › Research › peer-review

    15. Published

      Clonal hematopoiesis is associated with hematological toxicity during lenalidomide-based therapy for MCL

      Husby, Simon, Bæch-Laursen, C., Eskelund, C. W., Favero, Francesco, Jespersen, Jakob Schmidt, Hutchings, M., Pedersen, L. B., Niemann, Carsten, Weischenfeldt, Joachim Lütken, Räty, R., Larsen, T. S., Kolstad, A., Jerkeman, M. & Grønbæk, Kirsten, 2022, In: Leukemia. 36, p. 2912-2916

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Level of unique T cell clonotypes is associated with clonal hematopoiesis and survival in patients with lymphoma undergoing ASCT

      Husby, Simon, Jørgensen, G. Ø., Favero, Francesco, Jespersen, Jakob Schmidt, Rodriguez Gonzalez, Francisco G, Nielsen, C., Sorensen, B., Ebbesen, L. H., Bæch, J., Haastrup, E. K., Josefsson, P., Thorsgaard, M., Brown, Peter de Nully, El-Galaly, T. C., Larsen, T. S., Weischenfeldt, Joachim Lütken & Grønbæk, Kirsten, 2022, In: Bone Marrow Transplantation. 57, p. 674-677

      Research output: Contribution to journal › Letter › Research › peer-review

    17. Published

      Tumor mutational burden and purity adjustment before and after treatment with temozolomide in 27 paired samples of glioblastoma: a prospective study

      Nørøxe, D. S., Flynn, A., Yde, C. W., Østrup, O., Nielsen, Finn Cilius, Skjøth, Jane, Brennum, J., Hamerlik, P., Weischenfeldt, Joachim Lütken, Skovgaard Poulsen, H. & Lassen, Ulrik Niels, 2022, In: Molecular Oncology. 16, 1, p. 206-218

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Somatic structural variant formation is guided by and influences genome architecture

      Sidiropoulos, N., Mardin, B. R., Rodriguez Gonzalez, Francisco G, Bochkov, I. D., Garg, S., Stuetz, A. M., Korbel, J. O., Aiden, E. L. & Weischenfeldt, Joachim Lütken, 2022, In: Genome Research. 32, 4, p. 643-655

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Clonal Hematopoiesis and Epigenetic Age Acceleration in Elderly Danish Twins

      Sørensen, M., Tulstrup, Morten Rytter, Hansen, Jakob Werner, Weischenfeldt, Joachim Lütken, Grønbæk, Kirsten & Christensen, K., 2022, In: HemaSphere. 6, 9, 6 p., 768.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. 2021
    21. Published

      Mutations known from B-cell lymphoid malignancies are not found in CD34+ stem cells from patients with lymphoma

      Husby, Simon, Favero, Francesco, Rodriguez Gonzalez, Francisco G, Sutton, L. A., Haastrup, E. K., mxz703, mxz703, Hansen, Jakob Werner, Arboe, B., Aslan, D., Clasen-Linde, E., Gjerdrum, Lise Mette Rahbek, Gørlev, J. S., Brown, Peter de Nully, Fischer-Nielsen, A., Rosenquist, R., Weischenfeldt, Joachim Lütken & Grønbæk, Kirsten, 2021, In: Leukemia and Lymphoma. 62, 11, p. 2808-2811

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Systematic dissection of transcriptional regulatory networks by genome-scale and single-cell CRISPR screens

      Lopes, R., Sprouffske, K., Sheng, C., Uijttewaal, E. C. H., Wesdorp, A. E., Dahinden, J., Wengert, S., Diaz-Miyar, J., Yildiz, U., Bleu, M., Apfel, V., Mermet-Meillon, F., Krese, R., Eder, M., Olsen, A. V., Hoppe, P., Knehr, J., Carbone, W., Cuttat, R., Waldt, A. & 8 others, Altorfer, M., Naumann, U., Weischenfeldt, Joachim Lütken, deWeck, A., Kauffmann, A., Roma, G., Schübeler, D. & Galli, G. G., 2021, In: Science Advances. 7, 27, eabf5733.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      TET2 mutations are associated with hypermethylation at key regulatory enhancers in normal and malignant hematopoiesis

      Tulstrup, Morten Rytter, Soerensen, M., Hansen, Jakob Werner, Gillberg, Linn, Needhamsen, M., Kaastrup, K., Helin, K., Christensen, K., Weischenfeldt, Joachim Lütken & Grønbæk, Kirsten, 2021, In: Nature Communications. 12, 1, 10 p., 6061.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. 2020
    25. Published

      Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer

      Akdemir, K. C., Le, V. T., Chandran, S., Li, Y., Verhaak, R. G., Beroukhim, R., Campbell, P. J., Chin, L., Dixon, J. R., Futreal, P. A., Akdemir, K. C., Alvarez, E. G., Baez-Ortega, A., Beroukhim, R., Boutros, P. C., Bowtell, D. D. L., Brors, B., Burns, K. H., Campbell, P. J., Chan, K. & 32 others, Chen, K., Cortés-Ciriano, I., Dueso-Barroso, A., Dunford, A. J., Edwards, P. A., Estivill, X., Etemadmoghadam, D., Feuerbach, L., Fink, J. L., Frenkel-Morgenstern, M., Garsed, D. W., Gerstein, M., Gordenin, D. A., Haan, D., Haber, J. E., Hess, J. M., Hutter, B., Imielinski, M., Jones, D. T. W., Ju, Y. S., Kazanov, M. D., Klimczak, L. J., Koh, Y., Korbel, J. O., Kumar, K., Lee, E. A., Lee, J. J. K., Li, Y., Sidiropoulos, N., Weischenfeldt, Joachim Lütken, PCAWG Structural Variation Working Group, P. S. V. W. G. & PCAWG Consortium, P. C., 2020, In: Nature Genetics. p. 294-305

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples

      Bailey, M. H., Meyerson, W. U., Dursi, L. J., Wang, L. B., Dong, G., Liang, W. W., Weerasinghe, A., Li, S., Kelso, S., Akbani, R., Anur, P., Bailey, M. H., Buchanan, A., Chiotti, K., Covington, K., Creason, A., Ding, L., Weischenfeldt, J., Brunak, S., Ding, L. & 4 others, Favero, Francesco, MC3 Working Group, M. W. G., PCAWG novel somatic mutation calling methods working group, P. N. S. M. C. M. W. G. & PCAWG Consortium, P. C., 2020, In: Nature Communications. 11, 1, 4748.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis

      Carlevaro-Fita, J., Lanzós, A., Feuerbach, L., Hong, C., Mas-Ponte, D., Pedersen, J. S., Johnson, R., Sidiropoulos, N., Weischenfeldt, Joachim Lütken & Brunak, Søren, 2020, In: Communications Biology. 3, 1, p. 1-16 56.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing

      Cortés-Ciriano, I., Lee, J. J. K., Xi, R., Jain, D., Jung, Y. L., Yang, L., Gordenin, D., Klimczak, L. J., Zhang, C. Z., Pellman, D. S., Akdemir, K. C., Alvarez, E. G., Baez-Ortega, A., Beroukhim, R., Boutros, P. C., Bowtell, D. D. L., Brors, B., Burns, K. H., Campbell, P. J., Chan, K. & 32 others, Chen, K., Cortés-Ciriano, I., Dueso-Barroso, A., Dunford, A. J., Edwards, P. A., Estivill, X., Etemadmoghadam, D., Feuerbach, L., Fink, J. L., Frenkel-Morgenstern, M., Garsed, D. W., Gerstein, M., Gordenin, D. A., Haan, D., Haber, J. E., Hess, J. M., Hutter, B., Imielinski, M., Jones, D. T. W., Ju, Y. S., Kazanov, M. D., Klimczak, L. J., Koh, Y., Korbel, J. O., Kumar, K., Lee, E. A., Lee, J. J. K., Li, Y., Sidiropoulos, N., Weischenfeldt, Joachim Lütken, PCAWG Structural Variation Working Group, P. S. V. W. G. & PCAWG Consortium, P. C., 6 Feb 2020, In: Nature Genetics.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Clonal hematopoiesis evolves from pretreatment clones and stabilizes after end of chemotherapy in patients with MCL

      Eskelund, C. W., Husby, Simon, Favero, Francesco, Klausen, T. W., Rodriguez Gonzalez, Francisco G, Kolstad, A., Pedersen, L. B., Räty, R. K., Geisler, C. H., Jerkeman, M., Weischenfeldt, Joachim Lütken & Grønbæk, Kirsten, 2020, In: Blood. 135, 22, p. 2000-2004

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    30. Published

      Clonal hematopoiesis in elderly twins: concordance, discordance, and mortality

      Hansen, Jakob Werner, Pedersen, D. A., Larsen, L. A., Husby, Simon, Clemmensen, S. B., Hjelmborg, J., Favero, Francesco, Weischenfeldt, Joachim Lütken, Christensen, K. & Grønbæk, Kirsten, 2020, In: Blood. 135, 4, p. 261-268

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 3997200