Joachim Lütken Weischenfeldt
Group leader, Clinical Professor
Weischenfeldt Group
Københavns Universitet, BRIC, Ole Maaløes Vej 5
2200 København N
Member of:
- 2020
- Published
Clinical impact of clonal hematopoiesis in patients with lymphoma undergoing ASCT: a national population-based cohort study
Husby, S., Favero, F., Nielsen, C., Sørensen, B. S., Bæch, J., Grell, K., Hansen, J. W., Rodriguez-Gonzalez, F. G., Haastrup, E. K., Fischer-Nielsen, A., Andersen, P., Arboe, B., Sækmose, S. G., Hansen, P. B., Christiansen, I., Clasen-Linde, E., Meldgaard, L., Ebbesen, L. H., Segel, E. K., Josefsson, P. & 6 others, , 2020, In: Leukemia. 34, p. 3256-3268 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clonal hematopoiesis evolves from pretreatment clones and stabilizes after end of chemotherapy in patients with MCL
Eskelund, C. W., Husby, Simon, Favero, Francesco, Klausen, T. W., Rodriguez Gonzalez, Francisco G, Kolstad, A., Pedersen, L. B., Räty, R. K., Geisler, C. H., Jerkeman, M., Weischenfeldt, Joachim Lütken & Grønbæk, Kirsten, 2020, In: Blood. 135, 22, p. 2000-2004Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Clonal hematopoiesis in elderly twins: concordance, discordance, and mortality
Hansen, Jakob Werner, Pedersen, D. A., Larsen, L. A., Husby, Simon, Clemmensen, S. B., Hjelmborg, J., Favero, Francesco, Weischenfeldt, Joachim Lütken, Christensen, K. & Grønbæk, Kirsten, 2020, In: Blood. 135, 4, p. 261-268Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combined burden and functional impact tests for cancer driver discovery using DriverPower
Shuai, S., Abascal, F., Amin, S. B., Bader, G. D., Bandopadhayay, P., Barenboim, J., Beroukhim, R., Bertl, J., Boroevich, K. A., Brunak, S., Campbell, P. J., Carlevaro-Fita, J., Chakravarty, D., Chan, C. W. Y., Chen, K., Choi, J. K., Deu-Pons, J., Dhingra, P., Diamanti, K., Feuerbach, L. & 32 others, , 2020, In: Nature Communications. 11, 1, 12 p., 734.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer
Akdemir, K. C., Le, V. T., Chandran, S., Li, Y., Verhaak, R. G., Beroukhim, R., Campbell, P. J., Chin, L., Dixon, J. R., Futreal, P. A., Akdemir, K. C., Alvarez, E. G., Baez-Ortega, A., Beroukhim, R., Boutros, P. C., Bowtell, D. D. L., Brors, B., Burns, K. H., Campbell, P. J., Chan, K. & 32 others, , 2020, In: Nature Genetics. p. 294-305Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic footprints of activated telomere maintenance mechanisms in cancer
Sieverling, L., Hong, C., Koser, S. D., Ginsbach, P., Kleinheinz, K., Hutter, B., Braun, D. M., Cortés-Ciriano, I., Xi, R., Kabbe, R., Park, P. J., Eils, R., Schlesner, M., Akdemir, K. C., Alvarez, E. G., Baez-Ortega, A., Beroukhim, R., Boutros, P. C., Bowtell, D. D. L., Brors, B. & 32 others, , 2020, In: Nature Communications. 11, 1, 733.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations
Zhang, Y., Chen, F., Fonseca, N. A., He, Y., Fujita, M., Nakagawa, H., Zhang, Z., Brazma, A., Amin, S. B., Awadalla, P., Bailey, P. J., Brazma, A., Brooks, A. N., Calabrese, C., Chateigner, A., Cortés-Ciriano, I., Craft, B., Craft, D., Creighton, C. J., Davidson, N. R. & 33 others, , 2020, In: Nature Communications. 11, 1, p. 1-14 736.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of unique and shared mitochondrial DNA mutations in neurodegeneration and cancer by single-cell mitochondrial DNA structural variation sequencing (MitoSV-seq)
Jaberi, E., Tresse-Gommeaux, Emilie, Grønbæk, Kirsten, Weischenfeldt, Joachim Lütken & Issazadeh-Navikas, Shohreh, 2020, In: EBioMedicine. 57, p. 1-17 102868.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pan-cancer analysis of whole genomes
ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium, I. P. A. O. W. G. C., Weischenfeldt, Joachim Lütken, Sidiropoulos, N., Brunak, Søren & Rodriguez Gonzalez, Francisco G, 2020, In: Nature. 578, 7793, p. 82-93 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition
Rodriguez-Martin, B., Alvarez, E. G., Baez-Ortega, A., Zamora, J., Supek, F., Demeulemeester, J., Santamarina, M., Ju, Y. S., Temes, J., Garcia-Souto, D., Detering, H., Li, Y., Rodriguez-Castro, J., Dueso-Barroso, A., Bruzos, A. L., Dentro, S. C., Blanco, M. G., Contino, G., Ardeljan, D., Tojo, M. & 32 others, , 2020, In: Nature Genetics. 52, 3, p. 306-319 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pathway and network analysis of more than 2500 whole cancer genomes
Reyna, M. A., Haan, D., Paczkowska, M., Verbeke, L. P. C., Vazquez, M., Kahraman, A., Pulido-Tamayo, S., Barenboim, J., Wadi, L., Dhingra, P., Shrestha, R., Getz, G., Lawrence, M. S., Pedersen, J. S., Rubin, M. A., Wheeler, D. A., Brunak, S., Izarzugaza, J. M. G., Khurana, E., Marchal, K. & 32 others, , 2020, In: Nature Communications. 11, 1, p. 1-17 729.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Patterns of somatic structural variation in human cancer genomes
Li, Y., Roberts, N. D., Wala, J. A., Shapira, O., Schumacher, S. E., Kumar, K., Khurana, E., Waszak, S., Korbel, J. O., Haber, J. E., Imielinski, M., Akdemir, K. C., Alvarez, E. G., Baez-Ortega, A., Beroukhim, R., Boutros, P. C., Bowtell, D. D. L., Brors, B., Burns, K. H., Campbell, P. J. & 29 others, , 2020, In: Nature. 578, 7793, p. 112-121 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples
Bailey, M. H., Meyerson, W. U., Dursi, L. J., Wang, L. B., Dong, G., Liang, W. W., Weerasinghe, A., Li, S., Kelso, S., Akbani, R., Anur, P., Bailey, M. H., Buchanan, A., Chiotti, K., Covington, K., Creason, A., Ding, L., Weischenfeldt, J., Brunak, S., Ding, L. & 4 others, , 2020, In: Nature Communications. 11, 1, 4748.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Regulation of ETAA1-mediated ATR activation couples DNA replication fidelity and genome stability
Achuthankutty, D., Thakur, R. S., Haahr, Peter Thorlund, Hoffmann, Saskia, Drainas, A. P., Bizard, A. H., Weischenfeldt, Joachim Lütken, Hickson, Ian David & Mailand, Niels, 2019, In: The Journal of Cell Biology. 218, 12, 11 p., 3943.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Response to olaparib in a PALB2 germline mutated prostate cancer and genetic events associated with resistance
Horak, P., Weischenfeldt, J., von Amsberg, G., Beyer, B., Schütte, A., Uhrig, S., Gieldon, L., Klink, B., Feuerbach, L., Hübschmann, D., Kreutzfeldt, S., Heining, C., Maier, S., Hutter, B., Penzel, R., Schlesner, M., Eils, R., Sauter, G., Stenzinger, A., Brors, B. & 4 others, , 2019, In: Cold Spring Harbor molecular case studies. 5, 2, p. 1-9 a003657.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories
Gerhauser, C., Favero, F., Risch, T., Simon, R., Feuerbach, L., Assenov, Y., Heckmann, D., Sidiropoulos, N., Waszak, S. M., Hübschmann, D., Urbanucci, A., Girma, E. G., Kuryshev, V., Klimczak, L. J., Saini, N., Stütz, A. M., Weichenhan, D., Böttcher, L. M., Toth, R., Hendriksen, J. D. & 35 others, , 2018, In: Cancer Cell. 34, 6, p. 996-1011.e8 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort
Waszak, S. M., Northcott, P. A., Buchhalter, I., Robinson, G. W., Sutter, C., Groebner, S., Grund, K. B., Brugières, L., Jones, D. T. W., Pajtler, K. W., Morrissy, A. S., Kool, M., Sturm, D., Chavez, L., Ernst, A., Brabetz, S., Hain, M., Zichner, T., Segura-Wang, M., Weischenfeldt, J. & 67 others, , 2018, In: The Lancet Oncology. 19, 6, p. 785-798 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SvABA: genome-wide detection of structural variants and indels by local assembly
Wala, J. A., Bandopadhayay, P., Greenwald, N. F., O'Rourke, R., Sharpe, T., Stewart, C., Schumacher, S., Li, Y., Weischenfeldt, Joachim Lütken, Yao, X., Nusbaum, C., Campbell, P., Getz, G., Meyerson, M., Zhang, C., Imielinski, M. & Beroukhim, R., 2018, In: Genome Research. 28, 4, p. 581-591 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The landscape of genomic alterations across childhood cancers
ICGC PedBrain-Seq Project, I. P. P., 2018, In: Nature. 555, 7696, p. 321-327 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
Deletion lengthening at chromosomes 6q and 16q targets multiple tumor suppressor genes and is associated with an increasingly poor prognosis in prostate cancer
Kluth, M., Jung, S., Habib, O., Eshagzaiy, M., Heinl, A., Amschler, N., Masser, S., Mader, M., Runte, F., Barow, P., Frogh, S., Omari, J., Möller-Koop, C., Hube-Magg, C., Weischenfeldt, J., Korbel, J., Steurer, S., Krech, T., Huland, H., Graefen, M. & 4 others, , 12 Dec 2017, In: OncoTarget. 8, 65, p. 108923-108935 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial mutations drive prostate cancer aggression
Hopkins, J. F., Sabelnykova, V. Y., Weischenfeldt, J., Simon, R., Aguiar, J. A., Alkallas, R., Heisler, L. E., Zhang, J., Watson, J. D., Chua, M. L. K., Fraser, M., Favero, F., Lawerenz, C., Plass, C., Sauter, G., McPherson, J. D., Van Der Kwast, T., Korbel, J., Schlomm, T., Bristow, R. G. & 1 others, , 1 Dec 2017, In: Nature Communications. 8, 1, 8 p., 656.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomes of early onset prostate cancer
Weischenfeldt, Joachim Lütken & Korbel, J. O., 1 Sep 2017, In: Current Opinion in Urology. 27, 5, p. 481-487 7 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The whole-genome landscape of medulloblastoma subtypes
Northcott, P. A., Buchhalter, I., Morrissy, A. S., Hovestadt, V., Weischenfeldt, J., Ehrenberger, T., Gröbner, S., Segura-Wang, M., Zichner, T., Rudneva, V. A., Warnatz, H. J., Sidiropoulos, N., Phillips, A. H., Schumacher, S., Kleinheinz, K., Waszak, S. M., Erkek, S., Jones, D. T. W., Worst, B. C., Kool, M. & 67 others, , 19 Jul 2017, In: Nature. 547, 7663, p. 311-317 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijacking
Weischenfeldt, J. L., Dubash, T., Drainas, A. P., Mardin, B. R., Chen, Y., Stütz, A. M., Waszak, S. M., Bosco, G., Halvorsen, A. R., Raeder, B., Efthymiopoulos, T., Erkek, S., Siegl, C., Brenner, H., Brustugun, O. T., Dieter, S. M., Northcott, P. A., Petersen, I., Pfister, S. M., Schneider, M. & 12 others, , 2017, In: Nature Genetics. 49, 1, p. 65-74 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
Heterogeneity of ERG expression in prostate cancer: a large section mapping study of entire prostatectomy specimens from 125 patients
Tsourlakis, M., Stender, A., Quaas, A., Kluth, M., Wittmer, C., Haese, A., Graefen, M., Steurer, S., Simon, R., Korbel, J., Weischenfeldt, Joachim Lütken, Huland, H., Sauter, G., Schlomm, T. & Minner, S., 17 Aug 2016, In: B M C Cancer. 16, p. 641Research output: Contribution to journal › Journal article › Research › peer-review
ID: 3997200
Most downloads
-
2749
downloads
Mammalian tissues defective in nonsense-mediated mRNA decay display highly aberrant splicing patterns
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
415
downloads
The landscape of genomic alterations across childhood cancers
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
253
downloads
The whole-genome landscape of medulloblastoma subtypes
Research output: Contribution to journal › Journal article › Research › peer-review
Published