Krister Wennerberg
Professor
Wennerberg Group
Ole Maaløes Vej 5, 2200 København N.
Member of:
- 2024
- Published
Robust scoring of selective drug responses for patient-tailored therapy selection
Chen, Y., He, L., Ianevski, A., Ayuda-Durán, P., Potdar, S., Saarela, J., Miettinen, J. J., Kytölä, S., Miettinen, S., Manninen, M., Heckman, C. A., Enserink, J. M., Wennerberg, Krister & Aittokallio, T., 2024, In: Nature Protocols. 19, p. 60-82Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Ex vivo venetoclax sensitivity testing predicts treatment response in acute myeloid leukemia
Kuusanmäki, H., Kytölä, S., Vänttinen, I., Ruokoranta, T., Ranta, A., Huuhtanen, J., Suvela, M., Parsons, A., Holopainen, A., Partanen, A., Kuusisto, M. E. L., Koskela, S., Räty, R., Itälä-Remes, M., Västrik, I., Dufva, O., Siitonen, S., Porkka, K., Wennerberg, K., Heckman, C. A. & 5 others, , 2023, In: Haematologica. 108, 7, p. 1768-1781 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A platform for efficient establishment and drug-response profiling of high-grade serous ovarian cancer organoids
Senkowski, W., Gall-Mas, L., Falco, M. M., Li, Y., Lavikka, K., Kriegbaum, M. C., Oikkonen, J., Bulanova, D., Pietras, E. J., Voßgröne, K., Chen, Y. J., Erkan, E. P., Dai, J., Lundgren, A., Grønning Høg, M. K., Larsen, I. M., Lamminen, T., Kaipio, K., Huvila, J., Virtanen, A. & 9 others, , 2023, In: Developmental Cell. 58, 12, p. 1106-1121.e7 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Breeze 2.0: an interactive web-tool for visual analysis and comparison of drug response data
Potdar, S., Ianevski, F., Ianevski, A., Tanoli, Ziaurrehman, Wennerberg, Krister, Seashore-Ludlow, B., Kallioniemi, O., Ostling, P., Aittokallio, T. & Saarela, J., 2023, In: Nucleic Acids Research. 51, W1, p. W57-W61 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Erythroid/megakaryocytic differentiation confers BCL-XL dependency and venetoclax resistance in acute myeloid leukemia
Kuusanmäki, H., Dufva, O., Vähä-Koskela, M., Leppä, A-M., Huuhtanen, J., Vänttinen, I. M., Nygren, P. J., Klievink, J., Bouhlal, J. O. V., Pölönen, P., Zhang, Q., Adnan Awad, S., Mancebo-Pérez, C., Saad, J., Miettinen, J. J., Javarappa, K. K., Aakko, S., Ruokoranta, T., Eldfors, S., Heinäniemi, M. & 9 others, , 2023, In: Blood. 141, 13, p. 1610-1625Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PI3Kβ inhibition enhances ALK-inhibitor sensitivity in ALK-rearranged lung cancer
Talwelkar, S. S., Mayranpaa, M. I., Schuler, J., Linnavirta, N., Hemmes, A., Adinolfi, S., Kankainen, M., Sommergruber, W., Levonen, A., Rasanen, J., Knuuttila, A., Verschuren, E. W. & Wennerberg, Krister, 2023, In: Molecular Oncology. 17, 5, p. 747-764 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PP2A-based triple-strike therapy overcomes mitochondrial apoptosis resistance in brain cancer cells
Denisova, O. V., Merisaari, J., Huhtaniemi, R., Qiao, X., Yetukuri, L., Jumppanen, M., Kaur, A., Pääkkönen, M., von Schantz-Fant, С., Ohlmeyer, M., Wennerberg, Krister, Kauko, O., Koch, R., Aittokallio, T., Taipale, M. & Westermarck, J., 2023, In: Molecular Oncology. 17, 9, p. 1803-1820 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Standardized assays to monitor drug sensitivity in hematologic cancers
Ayuda-Durán, P., Hermansen, J. U., Giliberto, M., Yin, Y., Hanes, R., Gordon, Sandra, Kuusanmäki, Heikki Aleksi, Brodersen, A. M., Andersen, A. N., Taskén, K., Wennerberg, Krister, Enserink, J. M. & Skånland, S. S., 2023, In: Cell Death Discovery. 9, 13 p., 435.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synthetic lethal interaction between WEE1 and PKMYT1 is a target for multiple low-dose treatment of high-grade serous ovarian carcinoma
Benada, Jan, Bulanova, Daria, Azzoni, Violette Iridé Liliane, Petrosius, V., Ghazanfar, S., Wennerberg, Krister & Sørensen, Claus Storgaard, 2023, In: NAR Cancer. 5, 3, 13 p., zcad029.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Comprehensive and unbiased multiparameter high-throughput screening by compaRe finds effective and subtle drug responses in AML models
Chalabi Hajkarim, M., Karjalainen, E., Osipovitch, M., Dimopoulos, K., Gordon, Sandra, Ambri, F., Rasmussen, K. D., Grønbæk, Kirsten, Helin, K., Wennerberg, Krister & Won, K., 2022, In: eLife. 11, e73760.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Concurrent Inhibition of IGF1R and ERK Increases Pancreatic Cancer Sensitivity to Autophagy Inhibitors
Stalnecker, C. A., Grover, K. R., Edwards, A. C., Coleman, M. F., Yang, R., DeLiberty, J. M., Papke, B., Goodwin, C. M., Pierobon, M., Petricoin, E. F., Gautam, P., Wennerberg, Krister, Cox, A. D., Der, C. J., Hursting, S. D. & Bryant, K. L., 2022, In: Cancer Research. 82, 4, p. 586-598 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of actionable targets of multi-kinase inhibitors (AToMI) screening platform to dissect kinase targets of staurosporines in glioblastoma cells
Denisova, O. V., Merisaari, J., Kaur, A., Yetukuri, L., Jumppanen, M., von Schantz-Fant, C., Ohlmeyer, M., Wennerberg, Krister, Aittokallio, T., Taipale, M. & Westermarck, J., 2022, In: Scientific Reports. 12, 9 p., 13796.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of Wee1 inhibitor adavosertib on patient-derived high-grade serous ovarian cancer cells are multiple and independent of homologous recombination status
Roering, P., Siddiqui, A., Heuser, V. D., Potdar, S., Mikkonen, P., Oikkonen, J., Li, Y., Pikkusaari, S., Wennerberg, Krister, Hynninen, J., Grenman, S., Huhtinen, K., Auranen, A., Carpén, O. & Kaipio, K., 2022, In: Frontiers in Oncology. 12, 14 p., 954430.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Implementing a Functional Precision Medicine Tumor Board for Acute Myeloid Leukemia
Malani, D., Kumar, A., Brück, O., Kontro, M., Yadav, B., Hellesøy, M., Kuusanmäki, H., Dufva, O., Kankainen, M., Eldfors, S., Potdar, S., Saarela, J., Turunen, L., Parsons, A., Västrik, I., Kivinen, K., Saarela, J., Räty, R., Lehto, M., Wolf, M. & 7 others, , 2022, In: Cancer Discovery. 12, 2, p. 388-401 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Minimal information for chemosensitivity assays (MICHA): a next-generation pipeline to enable the FAIRification of drug screening experiments
Tanoli, Z., Aldahdooh, J., Alam, F., Wang, Y., Seemab, U., Fratelli, M., Pavlis, P., Hajduch, M., Bietrix, F., Gribbon, P., Zaliani, A., Hall, M. D., Shen, M., Brimacombe, K., Kulesskiy, E., Saarela, J., Wennerberg, Krister, Vähä-Koskela, M. & Tang, J., 2022, In: Briefings in Bioinformatics. 23, 1, 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protocol to utilize fresh uncultured human lung tumor cells for personalized functional diagnostics
Talwelkar, S. S., Lähdeniemi, I. A. K., Mäyränpää, M. I., Hemmes, A., Linnavirta, N., Räsänen, J., Knuuttila, A., Wennerberg, Krister & Verschuren, E. W., 2022, In: STAR Protocols. 3, 4, 19 p., 101720.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Bayesian multi-source regression and monocyte-associated gene expression predict BCL-2 inhibitor resistance in acute myeloid leukemia
White, B. S., Khan, S. A., Mason, M. J., Ammad-ud-din, M., Potdar, S., Malani, D., Kuusanmäki, Heikki Aleksi, Druker, B. J., Heckman, C., Kallioniemi, O., Kurtz, S. E., Porkka, K., Tognon, C. E., Tyner, J. W., Aittokallio, T., Wennerberg, Krister & Guinney, J., 2021, In: n p j Precision Oncology. 5, 1, 11 p., 71.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Crowdsourced mapping of unexplored target space of kinase inhibitors
Cichonska, A., Ravikumar, B., Allaway, R. J., Wan, F., Isayev, O., Li, S., Mason, M., Lamb, A., Tanoli, Z., Jeon, M., Kim, S., Popova, M., Capuzzi, S., Zeng, J., Dang, K., Koytiger, G., Kang, J., Wells, C. I., Willson, T. M., Oprea, T. I. & 6 others, , 2021, In: Nature Communications. 12, 1, 18 p., 3307.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exploration of databases and methods supporting drug repurposing: A comprehensive survey
Tanoli, Z., Seemab, U., Scherer, A., Wennerberg, Krister, Tang, J. & Vähä-Koskela, M., 2021, In: Briefings in Bioinformatics. 22, 2, p. 1656-1678 23 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Functional diagnostics using fresh uncultured lung tumor cells to guide personalized treatments
Talwelkar, S. S., Mäyränpää, M. I., Søraas, L., Potdar, S., Bao, J., Hemmes, A., Linnavirta, N., Lømo, J., Räsänen, J., Knuuttila, A., Wennerberg, Krister & Verschuren, E. W., 2021, In: Cell Reports Medicine. 2, 8, 21 p., 100373.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multi-modal meta-analysis of cancer cell line omics profiles identifies ECHDC1 as a novel breast tumor suppressor
Jaiswal, A., Gautam, P., Pietilä, E. A., Timonen, S., Nordström, N., Akimov, Y., Sipari, N., Tanoli, Z., Fleischer, T., Lehti, K., Wennerberg, Krister & Aittokallio, T., 2021, In: Molecular Systems Biology. 17, 3, p. 1-25 e9526.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Network-guided identification of cancer-selective combinatorial therapies in ovarian cancer
He, L., Bulanova, Daria, Oikkonen, J., Häkkinen, A., Zhang, K., Zheng, S., Wang, W., Erkan, E. P., Carpén, O., Joutsiniemi, T., Hietanen, S., Hynninen, J., Huhtinen, K., Hautaniemi, S., Vähärautio, A., Tang, J., Wennerberg, Krister & Aittokallio, T., 2021, In: Briefings in Bioinformatics. 22, 6, 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Patient-tailored design for selective co-inhibition of leukemic cell subpopulations
Ianevski, A., Lahtela, J., Javarappa, K. K., Sergeev, P., Ghimire, B. R., Gautam, P., Vähä-Koskela, M., Turunen, L., Linnavirta, N., Kuusanmäki, Heikki Aleksi, Kontro, M., Porkka, K., Heckman, C. A., Mattila, P., Wennerberg, Krister, Giri, A. K. & Aittokallio, T., 2021, In: Science Advances. 7, 8, eabe4038.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selective drug combination vulnerabilities in STAT3- And TP53-mutant malignant NK cells
Parri, E., Kuusanmäki, Heikki Aleksi, Bulanova, Daria, Mustjoki, S. & Wennerberg, Krister, 2021, In: Blood advances. 5, 7, p. 1862-1875Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
A normalized drug response metric improves accuracy and consistency of anticancer drug sensitivity quantification in cell-based screening
Gupta, A., Gautam, P., Wennerberg, Krister & Aittokallio, T., 2020, In: Communications Biology. 3, 1, p. 1-12Research output: Contribution to journal › Journal article › Research › peer-review
ID: 181406515
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147
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Genomic Perturbations Reveal Distinct Regulatory Networks in Intrahepatic Cholangiocarcinoma
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
107
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Targeting autophagy by small molecule inhibitors of vacuolar protein sorting 34 (Vps34) improves the sensitivity of breast cancer cells to Sunitinib
Research output: Contribution to journal › Journal article › Research › peer-review
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97
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Drug Target Commons 2.0: a community platform for systematic analysis of drug-target interaction profiles
Research output: Contribution to journal › Journal article › Research › peer-review
Published