Krister Wennerberg

Krister Wennerberg

Professor

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    ORCID: 0000-0002-1352-4220

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    1. p68RacGAP is a novel GTPase-activating protein that interacts with vascular endothelial zinc finger-1 and modulates endothelial cell capillary formation

      Aitsebaomo, J., Wennerberg, Krister, Der, C. J., Zhang, C., Kedar, V., Moser, M., Kingsley-Kallesen, M. L., Zeng, G. & Patterson, C., 23 Apr 2004, In: The Journal of Biological Chemistry. 279, 17, p. 17963-72 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Improved detection of differentially represented DNA barcodes for high-throughput clonal phenomics

      Akimov, Y., Bulanova, Daria, Timonen, S., Wennerberg, Krister & Aittokallio, T., 2020, In: Molecular Systems Biology. 16, 3, p. 1-18 e9195.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Rational Polypharmacology: Systematically Identifying and Engaging Multiple Drug Targets To Promote Axon Growth

      Al-Ali, H., Lee, D., Danzi, M. C., Nassif, H., Gautam, P., Wennerberg, Krister, Zuercher, B., Drewry, D. H., Lee, J. K., Lemmon, V. P. & Bixby, J. L., 21 Aug 2015, In: ACS chemical biology. 10, 8, p. 1939-51 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Global proteomics profiling improves drug sensitivity prediction: results from a multi-omics, pan-cancer modeling approach

      Ali, M., Khan, S. A., Wennerberg, Krister & Aittokallio, T., 15 Apr 2018, In: Bioinformatics (Online). 34, 8, p. 1353-1362 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Systematic identification of feature combinations for predicting drug response with Bayesian multi-view multi-task linear regression

      Ammad-Ud-Din, M., Khan, S. A., Wennerberg, Krister & Aittokallio, T., 15 Jul 2017, In: Bioinformatics (Online). 33, 14, p. i359-i368

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Integrative and personalized QSAR analysis in cancer by kernelized Bayesian matrix factorization

      Ammad-ud-din, M., Georgii, E., Gönen, M., Laitinen, T., Kallioniemi, O., Wennerberg, Krister, Poso, A. & Kaski, S., 25 Aug 2014, In: Journal of Chemical Information and Modeling. 54, 8, p. 2347-59 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Utilization of in situ ELISA method for examining Trk receptor phosphorylation in cultured cells

      Antila, H., Autio, H., Turunen, L., Harju, K., Tammela, P., Wennerberg, Krister, Yli-Kauhaluoma, J., Huttunen, H. J., Castrén, E. & Rantamäki, T., 30 Jan 2014, In: Journal of Neuroscience Methods. 222, p. 142-6 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. XPLN, a guanine nucleotide exchange factor for RhoA and RhoB, but not RhoC

      Arthur, W. T., Ellerbroek, S. M., Der, C. J., Burridge, K. & Wennerberg, Krister, 8 Nov 2002, In: The Journal of Biological Chemistry. 277, 45, p. 42964-72 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Global Human-Kinase Screening Identifies Therapeutic Host Targets against Influenza

      Atkins, C., Evans, C. W., Nordin, B., Patricelli, M. P., Reynolds, R., Wennerberg, Krister & Noah, J. W., Jul 2014, In: Journal of Biomolecular Screening. 19, 6, p. 936-46 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Standardized assays to monitor drug sensitivity in hematologic cancers

      Ayuda-Durán, P., Hermansen, J. U., Giliberto, M., Yin, Y., Hanes, R., Gordon, Sandra, Kuusanmäki, Heikki Aleksi, Brodersen, A. M., Andersen, A. N., Taskén, K., Wennerberg, Krister, Enserink, J. M. & Skånland, S. S., 2023, In: Cell Death Discovery. 9, 13 p., 435.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Synthetic lethal interaction between WEE1 and PKMYT1 is a target for multiple low-dose treatment of high-grade serous ovarian carcinoma

      Benada, Jan, Bulanova, Daria, Azzoni, Violette Iridé Liliane, Petrosius, V., Ghazanfar, S., Wennerberg, Krister & Sørensen, Claus Storgaard, 2023, In: NAR Cancer. 5, 3, 13 p., zcad029.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Drug sensitivity testing on patient-derived sarcoma cells predicts patient response to treatment and identifies c-Sarc inhibitors as active drugs for translocation sarcomas

      Brodin, B. A., Wennerberg, Krister, Lidbrink, E., Brosjö, O., Potdar, S., Wilson, J. N., Ma, L., Moens, L. N., Hesla, A., Porovic, E., Bernhardsson, E., Papakonstantinou, A., Bauer, H., Tsagkozis, P., Von Sivers, K., Wejde, J., Östling, P., Kallioniemi, O. & Stragliotto, C. L., 2019, In: British Journal of Cancer. 120, 4, p. 435-443 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Rho and Rac take center stage

      Burridge, K. & Wennerberg, Krister, 23 Jan 2004, In: Cell. 116, 2, p. 167-79 13 p.

      Research output: Contribution to journal › Review › Research › peer-review

    14. Published

      Comprehensive and unbiased multiparameter high-throughput screening by compaRe finds effective and subtle drug responses in AML models

      Chalabi Hajkarim, M., Karjalainen, E., Osipovitch, M., Dimopoulos, K., Gordon, Sandra, Ambri, F., Rasmussen, K. D., Grønbæk, Kirsten, Helin, K., Wennerberg, Krister & Won, K., 2022, In: eLife. 11, e73760.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Robust scoring of selective drug responses for patient-tailored therapy selection

      Chen, Y., He, L., Ianevski, A., Ayuda-Durán, P., Potdar, S., Saarela, J., Miettinen, J. J., Kytölä, S., Miettinen, S., Manninen, M., Heckman, C. A., Enserink, J. M., Wennerberg, Krister & Aittokallio, T., 2024, In: Nature Protocols. 19, p. 60-82

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Crowdsourced mapping of unexplored target space of kinase inhibitors

      Cichonska, A., Ravikumar, B., Allaway, R. J., Wan, F., Isayev, O., Li, S., Mason, M., Lamb, A., Tanoli, Z., Jeon, M., Kim, S., Popova, M., Capuzzi, S., Zeng, J., Dang, K., Koytiger, G., Kang, J., Wells, C. I., Willson, T. M., Oprea, T. I. & 6 others, Schlessinger, A., Drewry, D. H., Stolovitzky, G., Wennerberg, Krister, Guinney, J. & Aittokallio, T., 2021, In: Nature Communications. 12, 1, 18 p., 3307.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Computational-experimental approach to drug-target interaction mapping: A case study on kinase inhibitors

      Cichonska, A., Ravikumar, B., Parri, E., Timonen, S., Pahikkala, T., Airola, A., Wennerberg, Krister, Rousu, J. & Aittokallio, T., Aug 2017, In: PLOS Computational Biology. 13, 8, p. e1005678

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. A community effort to assess and improve drug sensitivity prediction algorithms

      NCI DREAM Community, N. D. C., Dec 2014, In: Nature Biotechnology. 32, 12, p. 1202-12 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Integrin signaling to the actin cytoskeleton

      DeMali, K. A., Wennerberg, Krister & Burridge, K., Oct 2003, In: Current Opinion in Cell Biology. 15, 5, p. 572-82 11 p.

      Research output: Contribution to journal › Review › Research › peer-review

    20. Published

      Development of actionable targets of multi-kinase inhibitors (AToMI) screening platform to dissect kinase targets of staurosporines in glioblastoma cells

      Denisova, O. V., Merisaari, J., Kaur, A., Yetukuri, L., Jumppanen, M., von Schantz-Fant, C., Ohlmeyer, M., Wennerberg, Krister, Aittokallio, T., Taipale, M. & Westermarck, J., 2022, In: Scientific Reports. 12, 9 p., 13796.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      PP2A-based triple-strike therapy overcomes mitochondrial apoptosis resistance in brain cancer cells

      Denisova, O. V., Merisaari, J., Huhtaniemi, R., Qiao, X., Yetukuri, L., Jumppanen, M., Kaur, A., Pääkkönen, M., von Schantz-Fant, С., Ohlmeyer, M., Wennerberg, Krister, Kauko, O., Koch, R., Aittokallio, T., Taipale, M. & Westermarck, J., 2023, In: Molecular Oncology. 17, 9, p. 1803-1820 18 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. A novel role for Lsc/p115 RhoGEF and LARG in regulating RhoA activity downstream of adhesion to fibronectin

      Dubash, A. D., Wennerberg, Krister, García-Mata, R., Menold, M. M., Arthur, W. T. & Burridge, K., 15 Nov 2007, In: Journal of Cell Science. 120, Pt 22, p. 3989-98 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Bioluminescent, Nonlytic, Real-Time Cell Viability Assay and Use in Inhibitor Screening

      Duellman, S. J., Zhou, W., Meisenheimer, P., Vidugiris, G., Cali, J. J., Gautam, P., Wennerberg, Krister & Vidugiriene, J., Oct 2015, In: ASSAY and Drug Development Technologies. 13, 8, p. 456-65 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Targeting autophagy by small molecule inhibitors of vacuolar protein sorting 34 (Vps34) improves the sensitivity of breast cancer cells to Sunitinib

      Dyczynski, M., Yu, Y., Otrocka, M., Parpal, S., Braga, T., Henley, A. B., Zazzi, H., Lerner, M., Wennerberg, Krister, Viklund, J., Martinsson, J., Grandér, D., De Milito, A. & Pokrovskaja Tamm, K., 2018, In: Cancer Letters. 435, p. 32-43 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. SGEF, a RhoG guanine nucleotide exchange factor that stimulates macropinocytosis

      Ellerbroek, S. M., Wennerberg, Krister, Arthur, W. T., Dunty, J. M., Bowman, D. R., DeMali, K. A., Der, C. & Burridge, K., Jul 2004, In: Molecular Biology of the Cell. 15, 7, p. 3309-19 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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