Krister Wennerberg

Krister Wennerberg

Professor

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    ORCID: 0000-0002-1352-4220

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    1. Published

      Phosphoproteome and drug-response effects mediated by the three protein phosphatase 2A inhibitor proteins CIP2A, SET, and PME-1

      Kauko, O., Imanishi, S. Y., Kulesskiy, E., Yetukuri, L., Laajala, T. D., Sharma, M., Pavic, K., Aakula, A., Rupp, C., Jumppanen, M., Haapaniemi, P., Ruan, L., Yadav, B., Suni, V., Varila, T., Corthals, G. L., Reimand, J., Wennerberg, Krister, Aittokallio, T. & Westermarck, J., 2020, In: Journal of Biological Chemistry. 295, 13, p. 4194-4211

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Comprehensive data-driven analysis of the impact of chemoinformatic structure on the genome-wide biological response profiles of cancer cells to 1159 drugs

      Khan, S. A., Faisal, A., Mpindi, J. P., Parkkinen, J. A., Kalliokoski, T., Poso, A., Kallioniemi, O. P., Wennerberg, Krister & Kaski, S., 30 May 2012, In: BMC Bioinformatics. 13, p. 112

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Identification of structural features in chemicals associated with cancer drug response: a systematic data-driven analysis

      Khan, S. A., Virtanen, S., Kallioniemi, O. P., Wennerberg, Krister, Poso, A. & Kaski, S., 1 Sep 2014, In: Bioinformatics (Online). 30, 17, p. i497-504

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Network pharmacology applications to map the unexplored target space and therapeutic potential of natural products

      Kibble, M., Saarinen, N., Tang, J., Wennerberg, Krister, Mäkelä, S. & Aittokallio, T., Aug 2015, In: Natural Product Reports. 32, 8, p. 1249-66 18 p.

      Research output: Contribution to journal › Review › Research › peer-review

    5. A transcriptomics data-driven gene space accurately predicts liver cytopathology and drug-induced liver injury

      Kohonen, P., Parkkinen, J. A., Willighagen, E. L., Ceder, R., Wennerberg, Krister, Kaski, S. & Grafström, R. C., 3 Jul 2017, In: Nature Communications. 8, p. 15932

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. High-Throughput Dual Screening Method for Ras Activities and Inhibitors

      Kopra, K., van Adrichem, A. J., Salo-Ahen, O. M. H., Peltonen, J., Wennerberg, Krister & Härmä, H., 18 Apr 2017, In: Analytical Chemistry. 89, 8, p. 4508-4516 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Somatic STAT3 mutations in large granular lymphocytic leukemia

      Koskela, H. L. M., Eldfors, S., Ellonen, P., van Adrichem, A. J., Kuusanmäki, H., Andersson, E. I., Lagström, S., Clemente, M. J., Olson, T., Jalkanen, S. E., Majumder, M. M., Almusa, H., Edgren, H., Lepistö, M., Mattila, P., Guinta, K., Koistinen, P., Kuittinen, T., Penttinen, K., Parsons, A. & 9 others, Knowles, J., Saarela, J., Wennerberg, Krister, Kallioniemi, O., Porkka, K., Loughran, T. P., Heckman, C. A., Maciejewski, J. P. & Mustjoki, S., 17 May 2012, In: The New England Journal of Medicine. 366, 20, p. 1905-13 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Mitochondria in Their Prime Drive Venetoclax Response in Acute Myeloid Leukemia

      Kriegbaum, M. C. & Wennerberg, Krister, 2020, In: Cancer Cell. 38, 6, p. 776-778 3 p.

      Research output: Contribution to journal › Journal article › Research

    9. Precision Cancer Medicine in the Acoustic Dispensing Era: Ex Vivo Primary Cell Drug Sensitivity Testing

      Kulesskiy, E., Saarela, J., Turunen, L. & Wennerberg, Krister, Feb 2016, In: Journal of laboratory automation. 21, 1, p. 27-36 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Ex vivo venetoclax sensitivity testing predicts treatment response in acute myeloid leukemia

      Kuusanmäki, H., Kytölä, S., Vänttinen, I., Ruokoranta, T., Ranta, A., Huuhtanen, J., Suvela, M., Parsons, A., Holopainen, A., Partanen, A., Kuusisto, M. E. L., Koskela, S., Räty, R., Itälä-Remes, M., Västrik, I., Dufva, O., Siitonen, S., Porkka, K., Wennerberg, K., Heckman, C. A. & 5 others, Ettala, P., Pyörälä, M., Rimpiläinen, J., Siitonen, T. & Kontro, M., 2023, In: Haematologica. 108, 7, p. 1768-1781 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Drug sensitivity profiling identifies potential therapies for lymphoproliferative disorders with overactive JAK/STAT3 signaling

      Kuusanmäki, H., Dufva, O., Parri, E., van Adrichem, A. J., Rajala, H., Majumder, M. M., Yadav, B., Parsons, A., Chan, W. C., Wennerberg, Krister, Mustjoki, S. & Heckman, C. A., 14 Nov 2017, In: OncoTarget. 8, 57, p. 97516-97527 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Erythroid/megakaryocytic differentiation confers BCL-XL dependency and venetoclax resistance in acute myeloid leukemia

      Kuusanmäki, H., Dufva, O., Vähä-Koskela, M., Leppä, A-M., Huuhtanen, J., Vänttinen, I. M., Nygren, P. J., Klievink, J., Bouhlal, J. O. V., Pölönen, P., Zhang, Q., Adnan Awad, S., Mancebo-Pérez, C., Saad, J., Miettinen, J. J., Javarappa, K. K., Aakko, S., Ruokoranta, T., Eldfors, S., Heinäniemi, M. & 9 others, Theilgaard-Mønch, Kim, Wartiovaara-Kautto, U., Keränen, M. A. I., Porkka, K., Konopleva, M., Wennerberg, Krister, Kontro, M., Heckman, C. A. & Mustjoki, S., 2023, In: Blood. 141, 13, p. 1610-1625

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Drug-sensitivity screening and genomic characterization of 45 hpV-negative head and neck carcinoma cell lines for novel biomarkers of drug efficacy

      Lepikhova, T., Karhemo, P. R., Louhimo, R., Yadav, B., Murumagi, A., Kulesskiy, E., Kivento, M., Sihto, H., Grenman, R., Syrjanen, S. M., Kallioniemi, O., Aittokallio, T., Wennerberg, Krister, Joensuu, H. & Monni, O., 2018, In: Molecular Cancer Therapeutics. 17, 9, p. 2060-2071 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. KIFC1 is a novel potential therapeutic target for breast cancer

      Li, Y., Lu, W., Chen, D., Boohaker, R. J., Zhai, L., Padmalayam, I., Wennerberg, Krister, Xu, B. & Zhang, W., 2015, In: Cancer Biology & Therapy. 16, 9, p. 1316-22 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. c-Abl Inhibitors Enable Insights into the Pathophysiology and Neuroprotection in Parkinson's Disease

      Lindholm, D., Pham, D. D., Cascone, A., Eriksson, O., Wennerberg, Krister & Saarma, M., 2016, In: Frontiers in Aging Neuroscience. 8, p. 254

      Research output: Contribution to journal › Review › Research › peer-review

    16. Published

      Multi-parametric single cell evaluation defines distinct drug responses in healthy hematologic cells that are retained in corresponding malignant cell types

      Majumder, M. M., Leppä, A., Hellesøy, M., Dowling, P., Malyutina, A., Kopperud, R., Bazou, D., Andersson, E., Parsons, A., Tang, J., Kallioniemi, O., Mustjoki, S., O’gorman, P., Wennerberg, Krister, Porkka, K., Gjertsen, B. T. & Heckman, C. A., 2020, In: Haematologica. 105, 6, p. 1527-1538

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      KIT pathway upregulation predicts dasatinib efficacy in acute myeloid leukemia

      Malani, D., Yadav, B., Kumar, A., Potdar, S., Kontro, M., Kankainen, M., Javarappa, K. K., Porkka, K., Wolf, M., Aittokallio, T., Wennerberg, Krister, Heckman, C. A., Murumägi, A. & Kallioniemi, O., 2020, In: Leukemia. 34, p. 2780-2784

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Implementing a Functional Precision Medicine Tumor Board for Acute Myeloid Leukemia

      Malani, D., Kumar, A., Brück, O., Kontro, M., Yadav, B., Hellesøy, M., Kuusanmäki, H., Dufva, O., Kankainen, M., Eldfors, S., Potdar, S., Saarela, J., Turunen, L., Parsons, A., Västrik, I., Kivinen, K., Saarela, J., Räty, R., Lehto, M., Wolf, M. & 7 others, Gjertsen, B. T., Mustjoki, S., Aittokallio, T., Wennerberg, Krister, Heckman, C. A., Kallioniemi, O. & Porkka, K., 2022, In: Cancer Discovery. 12, 2, p. 388-401 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Identification of novel small molecule activators of nuclear factor-κB with neuroprotective action via high-throughput screening

      Manuvakhova, M. S., Johnson, G. G., White, M. C., Ananthan, S., Sosa, M., Maddox, C., McKellip, S., Rasmussen, L., Wennerberg, Krister, Hobrath, J. V., White, E. L., Maddry, J. A. & Grimaldi, M., Jan 2011, In: Journal of Neuroscience Research. 89, 1, p. 58-72 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Consistency in drug response profiling

      Mpindi, J. P., Yadav, B., Östling, P., Gautam, P., Malani, D., Murumägi, A., Hirasawa, A., Kangaspeska, S., Wennerberg, Krister, Kallioniemi, O. & Aittokallio, T., 30 Nov 2016, In: Nature. 540, 7631, p. E5-E6

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Impact of normalization methods on high-throughput screening data with high hit rates and drug testing with dose-response data

      Mpindi, J., Swapnil, P., Dmitrii, B., Jani, S., Saeed, K., Wennerberg, Krister, Aittokallio, T., Östling, P. & Kallioniemi, O., 1 Dec 2015, In: Bioinformatics (Online). 31, 23, p. 3815-21 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Genomic Perturbations Reveal Distinct Regulatory Networks in Intrahepatic Cholangiocarcinoma

      Nepal, C., O'Rourke, Colm, Oliveira, D. V., Taranta, A., Shema, S., Gautam, P., Calderaro, J., Barbour, A., Raggi, C., Wennerberg, Krister, Wang, X. W., Lautem, A., Roberts, L. R. & Andersen, Jesper Bøje, Sep 2018, In: Hepatology. 68, 3, p. 949-963 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Identification of novel regulators of STAT3 activity

      Parri, E., Kuusanmäki, Heikki Aleksi, Van Adrichem, A. J., Kaustio, M. & Wennerberg, Krister, 2020, In: PLoS ONE. 15, 3, p. 1-18 e0230819.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Selective drug combination vulnerabilities in STAT3- And TP53-mutant malignant NK cells

      Parri, E., Kuusanmäki, Heikki Aleksi, Bulanova, Daria, Mustjoki, S. & Wennerberg, Krister, 2021, In: Blood advances. 5, 7, p. 1862-1875

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Individualized systems medicine strategy to tailor treatments for patients with chemorefractory acute myeloid leukemia

      Pemovska, T., Kontro, M., Yadav, B., Edgren, H., Eldfors, S., Szwajda, A., Almusa, H., Bespalov, M. M., Ellonen, P., Elonen, E., Gjertsen, B. T., Karjalainen, R., Kulesskiy, E., Lagström, S., Lehto, A., Lepistö, M., Lundán, T., Majumder, M. M., Marti, J. M. L., Mattila, P. & 16 others, Murumägi, A., Mustjoki, S., Palva, A., Parsons, A., Pirttinen, T., Rämet, M. E., Suvela, M., Turunen, L., Västrik, I., Wolf, M., Knowles, J., Aittokallio, T., Heckman, C. A., Porkka, K., Kallioniemi, O. & Wennerberg, Krister, Dec 2013, In: Cancer Discovery. 3, 12, p. 1416-29 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 181406515