Krister Wennerberg

Krister Wennerberg

Professor

Member of:

    ORCID: 0000-0002-1352-4220

    Publication year:
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    26 - 50 out of 122Page size: 25
    1. 2020
    2. Published

      ALDH1A1‐related stemness in high‐grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR‐PI3K/aurora kinase inhibitors

      Kaipio, K., Chen, P., Roering, P., Huhtinen, K., Mikkonen, P., Östling, P., Lehtinen, L., Mansuri, N., Korpela, T., Potdar, S., Hynninen, J., Auranen, A., Grénman, S., Wennerberg, Krister, Hautaniemi, S. & Carpén, O., 2020, In: Journal of Pathology. 250, 2, p. 159-169 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Abstract P6-10-28: Therapeutic stratification of triple negative breast cancer by integrating chemosensitivity & phospho-proteome profiles

      Gautam, P., Qin, X., Vainonen, J., Nagelli, S., Lampe, J., Klefström, J., Westermarck, J., Wennerberg, Krister & Aittokallio, T., 2020.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    4. Published

      Atypical KRASG12R mutant is impaired in PI3K signaling and macropinocytosis in pancreatic cancer

      Hobbs, G. A., Baker, N. M., Miermont, A. M., Thurman, R. D., Pierobon, M., Tran, T. H., Anderson, A. O., Waters, A. M., Diehl, J. N., Papke, B., Hodge, R. G., Klomp, J. E., Goodwin, C. M., DeLiberty, J. M., Wang, J., Ng, R. W. S., Gautam, P., Bryant, K. L., Esposito, D., Campbell, S. L. & 8 others, Petricoin, E. F., Simanshu, D. K., Aguirre, A. J., Wolpin, B. M., Wennerberg, Krister, Rudloff, U., Cox, A. D. & Der, C. J., 2020, In: Cancer Discovery. 10, 1, p. 104-123 20 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Breeze: an integrated quality control and data analysis application for high-throughput drug screening

      Potdar, S., Ianevski, A., Mpindi, J., Bychkov, D., Fiere, C., Ianevski, P., Yadav, B., Wennerberg, Krister, Aittokallio, T., Kallioniemi, O., Saarela, J. & Östling, P., 2020, In: Bioinformatics. 36, 11, p. 3602-3604

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Human Tumor–Derived Matrix Improves the Predictability of Head and Neck Cancer Drug Testing

      Tuomainen, K., Al-samadi, A., Potdar, S., Turunen, L., Turunen, M., Karhemo, P., Bergman, P., Risteli, M., Åström, P., Tiikkaja, R., Grenman, R., Wennerberg, Krister, Monni, O. & Salo, T., 2020, In: Cancers. 12, 1, 92.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Identification of novel regulators of STAT3 activity

      Parri, E., Kuusanmäki, Heikki Aleksi, Van Adrichem, A. J., Kaustio, M. & Wennerberg, Krister, 2020, In: PLoS ONE. 15, 3, p. 1-18 e0230819.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Improved detection of differentially represented DNA barcodes for high-throughput clonal phenomics

      Akimov, Y., Bulanova, Daria, Timonen, S., Wennerberg, Krister & Aittokallio, T., 2020, In: Molecular Systems Biology. 16, 3, p. 1-18 e9195.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Interactive visual analysis of drug–target interaction networks using Drug Target Profiler, with applications to precision medicine and drug repurposing

      Tanoli, Z., Alam, Z., Ianevski, A., Wennerberg, Krister, Vähä-koskela, M. & Aittokallio, T., 2020, In: Briefings in Bioinformatics. 21, 1, p. 211-220

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      KIT pathway upregulation predicts dasatinib efficacy in acute myeloid leukemia

      Malani, D., Yadav, B., Kumar, A., Potdar, S., Kontro, M., Kankainen, M., Javarappa, K. K., Porkka, K., Wolf, M., Aittokallio, T., Wennerberg, Krister, Heckman, C. A., Murumägi, A. & Kallioniemi, O., 2020, In: Leukemia. 34, p. 2780-2784

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Mitochondria in Their Prime Drive Venetoclax Response in Acute Myeloid Leukemia

      Kriegbaum, M. C. & Wennerberg, Krister, 2020, In: Cancer Cell. 38, 6, p. 776-778 3 p.

      Research output: Contribution to journal › Journal article › Research

    12. Published

      Multi-parametric single cell evaluation defines distinct drug responses in healthy hematologic cells that are retained in corresponding malignant cell types

      Majumder, M. M., Leppä, A., Hellesøy, M., Dowling, P., Malyutina, A., Kopperud, R., Bazou, D., Andersson, E., Parsons, A., Tang, J., Kallioniemi, O., Mustjoki, S., O’gorman, P., Wennerberg, Krister, Porkka, K., Gjertsen, B. T. & Heckman, C. A., 2020, In: Haematologica. 105, 6, p. 1527-1538

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Pan-RAF inhibition induces apoptosis in acute myeloid leukemia cells and synergizes with BCL2 inhibition

      Tambe, M., Karjalainen, E., Vähä-Koskela, M., Bulanova, Daria, Gjertsen, B. T., Kontro, M., Porkka, K., Heckman, C. A. & Wennerberg, Krister, 2020, In: Leukemia. 34, p. 3186-3196

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Phosphoproteome and drug-response effects mediated by the three protein phosphatase 2A inhibitor proteins CIP2A, SET, and PME-1

      Kauko, O., Imanishi, S. Y., Kulesskiy, E., Yetukuri, L., Laajala, T. D., Sharma, M., Pavic, K., Aakula, A., Rupp, C., Jumppanen, M., Haapaniemi, P., Ruan, L., Yadav, B., Suni, V., Varila, T., Corthals, G. L., Reimand, J., Wennerberg, Krister, Aittokallio, T. & Westermarck, J., 2020, In: Journal of Biological Chemistry. 295, 13, p. 4194-4211

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Therapeutic targeting of KSP in preclinical models of high-risk neuroblastoma

      Hansson, K., Radke, K., Aaltonen, K., Saarela, J., Mañas, A., Sjölund, J., Smith, E. M., Pietras, K., Påhlman, S., Wennerberg, Krister, Gisselsson, D. & Bexell, D., 2020, In: Science Translational Medicine. 12, 562, p. 1-17 eaba4434.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. 2019
    17. Published

      Abstract P2-06-25: A phenotypic screening and machine learning platform efficiently identifies triple negative breast cancer-selective and readily druggable targets

      Gautam, P., Jaiswal, A., Aittokallio, T., Hassan, A. & Wennerberg, Krister, 2019, In: Cancer Research. p. P2-06-25-P2-06-25

      Research output: Contribution to journal › Conference abstract in journal › Research

    18. Published

      Chemogenomic Analysis of the Druggable Kinome and Its Application to Repositioning and Lead Identification Studies

      Ravikumar, B., Timonen, S., Alam, Z., Parri, E., Wennerberg, Krister & Aittokallio, T., 2019, In: Cell Chemical Biology. 26, 11, p. 1608-1622

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Drug screening and molecular profiling identifies INKA1 as a predictive biomarker for sensitivity to MAPK inhibition-antimitotic combination treatment in pancreatic ductal adenocarcinoma

      Gautam, P., Vaha-Koskela, M., Tomlinson, M., Cox, A. D., Der, C. J., Aittokallio, T. & Wennerberg, Krister, 2019, In: Molecular Cancer Therapeutics. 18, 12, A137.

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    20. Published

      Drug sensitivity testing on patient-derived sarcoma cells predicts patient response to treatment and identifies c-Sarc inhibitors as active drugs for translocation sarcomas

      Brodin, B. A., Wennerberg, Krister, Lidbrink, E., Brosjö, O., Potdar, S., Wilson, J. N., Ma, L., Moens, L. N., Hesla, A., Porovic, E., Bernhardsson, E., Papakonstantinou, A., Bauer, H., Tsagkozis, P., Von Sivers, K., Wejde, J., Östling, P., Kallioniemi, O. & Stragliotto, C. L., 2019, In: British Journal of Cancer. 120, 4, p. 435-443 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Network pharmacology modeling identifies synergistic Aurora B and ZAK interaction in triple-negative breast cancer

      Tang, J., Gautam, P., Gupta, A., He, L., Timonen, S., Akimov, Y., Wang, W., Szwajda, A., Jaiswal, A., Turei, D., Yadav, B., Kankainen, M., Saarela, J., Saez-rodriguez, J., Wennerberg, Krister & Aittokallio, T., 2019, In: npj Systems Biology and Applications. 5, 1, 5.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Phenotypic Screening Combined with Machine Learning for Efficient Identification of Breast Cancer-Selective Therapeutic Targets

      Gautam, P., Jaiswal, A., Aittokallio, T., Al-ali, H. & Wennerberg, Krister, 2019, In: Cell Chemical Biology. 26, 7, p. 970-979

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Prediction of drug combination effects with a minimal set of experiments

      Ianevski, A., Giri, A. K., Gautam, P., Kononov, A., Potdar, S., Saarela, J., Wennerberg, Krister & Aittokallio, T., 2019, In: Nature Machine Intelligence. 1, 12, p. 568-577

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Receptor Tyrosine Kinase Signaling Networks Define Sensitivity to ERBB Inhibition and Stratify Kras-Mutant Lung Cancers

      Talwelkar, S. S., Nagaraj, A. S., Devlin, J. R., Hemmes, A., Potdar, S., Kiss, E. A., Saharinen, P., Salmenkivi, K., Mäyränpää, M. I., Wennerberg, Krister & Verschuren, E. W., 2019, In: Molecular Cancer Therapeutics. 18, 10, p. 1863-1874

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. 2018
    26. Published

      Genomic Perturbations Reveal Distinct Regulatory Networks in Intrahepatic Cholangiocarcinoma

      Nepal, C., O'Rourke, Colm, Oliveira, D. V., Taranta, A., Shema, S., Gautam, P., Calderaro, J., Barbour, A., Raggi, C., Wennerberg, Krister, Wang, X. W., Lautem, A., Roberts, L. R. & Andersen, Jesper Bøje, Sep 2018, In: Hepatology. 68, 3, p. 949-963 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      PP2A inhibition is a druggable MEK inhibitor resistance mechanism in KRAS-mutant lung cancer cells

      Kauko, O., O’Connor, C. M., Kulesskiy, E., Sangodkar, J., Aakula, A., Izadmehr, S., Yetukuri, L., Yadav, B., Padzik, A., Laajala, T. D., Haapaniemi, P., Momeny, M., Varila, T., Ohlmeyer, M., Aittokallio, T., Wennerberg, Krister, Narla, G. & Westermarck, J., 18 Jul 2018, In: Science Translational Medicine. 10, 450, p. 1-12 12 p., eaaq1093.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Patient-Customized Drug Combination Prediction and Testing for T-cell Prolymphocytic Leukemia Patients

      He, L., Tang, J., Andersson, E. I., Timonen, S., Koschmieder, S., Wennerberg, Krister, Mustjoki, S. & Aittokallio, T., 1 May 2018, In: Cancer Research. 78, 9, p. 2407-2418 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 181406515