Krister Wennerberg

Krister Wennerberg

Professor

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    ORCID: 0000-0002-1352-4220

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    1. 2018

    2. Global proteomics profiling improves drug sensitivity prediction: results from a multi-omics, pan-cancer modeling approach

      Ali, M., Khan, S. A., Wennerberg, Krister & Aittokallio, T., 15 Apr 2018, In: Bioinformatics (Online). 34, 8, p. 1353-1362 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Drug Target Commons: A Community Effort to Build a Consensus Knowledge Base for Drug-Target Interactions

      Tang, J., Tanoli, Z-U-R., Ravikumar, B., Alam, Z., Rebane, A., Vähä-Koskela, M., Peddinti, G., van Adrichem, A. J., Wakkinen, J., Jaiswal, A., Karjalainen, E., Gautam, P., He, L., Parri, E., Khan, S., Gupta, A., Ali, M., Yetukuri, L., Gustavsson, A-L., Seashore-Ludlow, B. & 6 others, Hersey, A., Leach, A. R., Overington, J. P., Repasky, G., Wennerberg, Krister & Aittokallio, T., 15 Feb 2018, In: Cell Chemical Biology. 25, 2, p. 224-229.e2

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Drug Target Commons 2.0: a community platform for systematic analysis of drug-target interaction profiles

      Tanoli, Z. R., Alam, Z., Vähä-Koskela, M., Ravikumar, B., Malyutina, A., Jaiswal, A., Tang, J., Wennerberg, Krister & Aittokallio, T., 2018, In: Database: The Journal of Biological Databases and Curation. 2018, 2018, p. 1-13 13 p., bay083.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Drug-sensitivity screening and genomic characterization of 45 hpV-negative head and neck carcinoma cell lines for novel biomarkers of drug efficacy

      Lepikhova, T., Karhemo, P. R., Louhimo, R., Yadav, B., Murumagi, A., Kulesskiy, E., Kivento, M., Sihto, H., Grenman, R., Syrjanen, S. M., Kallioniemi, O., Aittokallio, T., Wennerberg, Krister, Joensuu, H. & Monni, O., 2018, In: Molecular Cancer Therapeutics. 17, 9, p. 2060-2071 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism

      Vaseva, A. V., Blake, D. R., Gilbert, T. S. K., Ng, S., Hostetter, G., Azam, S. H., Ozkan-Dagliyan, I., Gautam, P., Bryant, K. L., Pearce, K. H., Herring, L. E., Han, H., Graves, L. M., Witkiewicz, A. K., Knudsen, E. S., Pecot, C. V., Rashid, N., Houghton, P. J., Wennerberg, K., Cox, A. D. & 1 others, Der, C. J., 2018, In: Cancer Cell. 34, 5, p. 807-822.e1-e7 23 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Methods for High-throughput Drug Combination Screening and Synergy Scoring

      He, L., Kulesskiy, E., Saarela, J., Turunen, L., Wennerberg, Krister, Aittokallio, T. & Tang, J., 2018, In: Methods in molecular biology (Clifton, N.J.). 1711, p. 351-398 48 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Targeting autophagy by small molecule inhibitors of vacuolar protein sorting 34 (Vps34) improves the sensitivity of breast cancer cells to Sunitinib

      Dyczynski, M., Yu, Y., Otrocka, M., Parpal, S., Braga, T., Henley, A. B., Zazzi, H., Lerner, M., Wennerberg, Krister, Viklund, J., Martinsson, J., Grandér, D., De Milito, A. & Pokrovskaja Tamm, K., 2018, In: Cancer Letters. 435, p. 32-43 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Toward universal protein post-translational modification detection in high throughput format

      Härmä, H., Tong-Ochoa, N., van Adrichem, A. J., Jelesarov, I., Wennerberg, Krister & Kopra, K., 2018, In: Chemical communications (Cambridge, England). 54, 23, p. 2910-2913 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. 2017

    11. A Community Challenge for Inferring Genetic Predictors of Gene Essentialities through Analysis of a Functional Screen of Cancer Cell Lines

      Broad-DREAM Community, B. C., 22 Nov 2017, In: Cell Systems. 5, 5, p. 485-497.e3

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Drug sensitivity profiling identifies potential therapies for lymphoproliferative disorders with overactive JAK/STAT3 signaling

      Kuusanmäki, H., Dufva, O., Parri, E., van Adrichem, A. J., Rajala, H., Majumder, M. M., Yadav, B., Parsons, A., Chan, W. C., Wennerberg, Krister, Mustjoki, S. & Heckman, C. A., 14 Nov 2017, In: OncoTarget. 8, 57, p. 97516-97527 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. JAK1/2 and BCL2 inhibitors synergize to counteract bone marrow stromal cell-induced protection of AML

      Karjalainen, R., Pemovska, T., Popa, M., Liu, M., Javarappa, K. K., Majumder, M. M., Yadav, B., Tamborero, D., Tang, J., Bychkov, D., Kontro, M., Parsons, A., Suvela, M., Mayoral Safont, M., Porkka, K., Aittokallio, T., Kallioniemi, O., McCormack, E., Gjertsen, B. T., Wennerberg, K. & 2 others, Knowles, J. & Heckman, C. A., 10 Aug 2017, In: Blood. 130, 6, p. 789-802 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Computational-experimental approach to drug-target interaction mapping: A case study on kinase inhibitors

      Cichonska, A., Ravikumar, B., Parri, E., Timonen, S., Pahikkala, T., Airola, A., Wennerberg, Krister, Rousu, J. & Aittokallio, T., Aug 2017, In: PLOS Computational Biology. 13, 8, p. e1005678

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Systematic identification of feature combinations for predicting drug response with Bayesian multi-view multi-task linear regression

      Ammad-Ud-Din, M., Khan, S. A., Wennerberg, Krister & Aittokallio, T., 15 Jul 2017, In: Bioinformatics (Online). 33, 14, p. i359-i368

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. A transcriptomics data-driven gene space accurately predicts liver cytopathology and drug-induced liver injury

      Kohonen, P., Parkkinen, J. A., Willighagen, E. L., Ceder, R., Wennerberg, Krister, Kaski, S. & Grafström, R. C., 3 Jul 2017, In: Nature Communications. 8, p. 15932

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Seed-effect modeling improves the consistency of genome-wide loss-of-function screens and identifies synthetic lethal vulnerabilities in cancer cells

      Jaiswal, A., Peddinti, G., Akimov, Y., Wennerberg, Krister, Kuznetsov, S., Tang, J. & Aittokallio, T., 1 Jun 2017, In: Genome Medicine. 9, 1, p. 51

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. High-Throughput Dual Screening Method for Ras Activities and Inhibitors

      Kopra, K., van Adrichem, A. J., Salo-Ahen, O. M. H., Peltonen, J., Wennerberg, Krister & Härmä, H., 18 Apr 2017, In: Analytical Chemistry. 89, 8, p. 4508-4516 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Differentiation status of primary chronic myeloid leukemia cells affects sensitivity to BCR-ABL1 inhibitors

      Pietarinen, P. O., Eide, C. A., Ayuda-Durán, P., Potdar, S., Kuusanmäki, H., Andersson, E. I., Mpindi, J. P., Pemovska, T., Kontro, M., Heckman, C. A., Kallioniemi, O., Wennerberg, Krister, Hjorth-Hansen, H., Druker, B. J., Enserink, J. M., Tyner, J. W., Mustjoki, S. & Porkka, K., 4 Apr 2017, In: OncoTarget. 8, 14, p. 22606-22615 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Comprehensive Drug Testing of Patient-derived Conditionally Reprogrammed Cells from Castration-resistant Prostate Cancer

      Saeed, K., Rahkama, V., Eldfors, S., Bychkov, D., Mpindi, J. P., Yadav, B., Paavolainen, L., Aittokallio, T., Heckman, C., Wennerberg, Krister, Peehl, D. M., Horvath, P., Mirtti, T., Rannikko, A., Kallioniemi, O., Östling, P. & Af Hällström, T. M., Mar 2017, In: European Urology (Italian Edition). 71, 3, p. 319-327 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Systematic drug sensitivity testing reveals synergistic growth inhibition by dasatinib or mTOR inhibitors with paclitaxel in ovarian granulosa cell tumor cells

      Haltia, U., Andersson, N., Yadav, B., Färkkilä, A., Kulesskiy, E., Kankainen, M., Tang, J., Bützow, R., Riska, A., Leminen, A., Heikinheimo, M., Kallioniemi, O., Unkila-Kallio, L., Wennerberg, Krister, Aittokallio, T. & Anttonen, M., Mar 2017, In: Gynecologic Oncology. 144, 3, p. 621-630 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. 2016

    23. Consistency in drug response profiling

      Mpindi, J. P., Yadav, B., Östling, P., Gautam, P., Malani, D., Murumägi, A., Hirasawa, A., Kangaspeska, S., Wennerberg, Krister, Kallioniemi, O. & Aittokallio, T., 30 Nov 2016, In: Nature. 540, 7631, p. E5-E6

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Cancer Cell Drug Response Transcriptomes in 3D

      Wennerberg, Krister, 17 Nov 2016, In: Cell Chemical Biology. 23, 11, p. 1323-1324 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Identification of selective cytotoxic and synthetic lethal drug responses in triple negative breast cancer cells

      Gautam, P., Karhinen, L., Szwajda, A., Jha, S. K., Yadav, B., Aittokallio, T. & Wennerberg, Krister, 10 May 2016, In: Molecular Cancer. 15, 1, p. 34

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Discovery of berberine, abamectin and ivermectin as antivirals against chikungunya and other alphaviruses

      Varghese, F. S., Kaukinen, P., Gläsker, S., Bespalov, M., Hanski, L., Wennerberg, Krister, Kümmerer, B. M. & Ahola, T., Feb 2016, In: Antiviral Research. 126, p. 117-24 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Precision Cancer Medicine in the Acoustic Dispensing Era: Ex Vivo Primary Cell Drug Sensitivity Testing

      Kulesskiy, E., Saarela, J., Turunen, L. & Wennerberg, Krister, Feb 2016, In: Journal of laboratory automation. 21, 1, p. 27-36 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Long-Term ERK Inhibition in KRAS-Mutant Pancreatic Cancer Is Associated with MYC Degradation and Senescence-like Growth Suppression

      Hayes, T. K., Neel, N. F., Hu, C., Gautam, P., Chenard, M., Long, B., Aziz, M., Kassner, M., Bryant, K. L., Pierobon, M., Marayati, R., Kher, S., George, S. D., Xu, M., Wang-Gillam, A., Samatar, A. A., Maitra, A., Wennerberg, K., Petricoin, E. F., Yin, H. H. & 4 others, Nelkin, B., Cox, A. D., Yeh, J. J. & Der, C. J., 11 Jan 2016, In: Cancer Cell. 29, 1, p. 75-89 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 181406515