Krister Wennerberg
Professor
Wennerberg Group
Ole Maaløes Vej 5, 2200 København N.
Member of:
- 2016
c-Abl Inhibitors Enable Insights into the Pathophysiology and Neuroprotection in Parkinson's Disease
Lindholm, D., Pham, D. D., Cascone, A., Eriksson, O., Wennerberg, Krister & Saarma, M., 2016, In: Frontiers in Aging Neuroscience. 8, p. 254Research output: Contribution to journal › Review › Research › peer-review
- 2015
MgcRacGAP inhibition stimulates JAK-dependent STAT3 activity
van Adrichem, A. J. & Wennerberg, Krister, 21 Dec 2015, In: FEBS Letters. 589, 24 Pt B, p. 3859-65 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Impact of normalization methods on high-throughput screening data with high hit rates and drug testing with dose-response data
Mpindi, J., Swapnil, P., Dmitrii, B., Jani, S., Saeed, K., Wennerberg, Krister, Aittokallio, T., Östling, P. & Kallioniemi, O., 1 Dec 2015, In: Bioinformatics (Online). 31, 23, p. 3815-21 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Relevance Rank Platform (RRP) for Functional Filtering of High Content Protein-Protein Interaction Data
Pokharel, Y. R., Saarela, J., Szwajda, A., Rupp, C., Rokka, A., Lal Kumar Karna, S., Teittinen, K., Corthals, G., Kallioniemi, O., Wennerberg, Krister, Aittokallio, T. & Westermarck, J., Dec 2015, In: Molecular and Cellular Proteomics. 14, 12, p. 3274-83 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
From drug response profiling to target addiction scoring in cancer cell models
Yadav, B., Gopalacharyulu, P., Pemovska, T., Khan, S. A., Szwajda, A., Tang, J., Wennerberg, Krister & Aittokallio, T., 1 Oct 2015, In: Disease models & mechanisms. 8, 10, p. 1255-64 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Bioluminescent, Nonlytic, Real-Time Cell Viability Assay and Use in Inhibitor Screening
Duellman, S. J., Zhou, W., Meisenheimer, P., Vidugiris, G., Cali, J. J., Gautam, P., Wennerberg, Krister & Vidugiriene, J., Oct 2015, In: ASSAY and Drug Development Technologies. 13, 8, p. 456-65 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Rational Polypharmacology: Systematically Identifying and Engaging Multiple Drug Targets To Promote Axon Growth
Al-Ali, H., Lee, D., Danzi, M. C., Nassif, H., Gautam, P., Wennerberg, Krister, Zuercher, B., Drewry, D. H., Lee, J. K., Lemmon, V. P. & Bixby, J. L., 21 Aug 2015, In: ACS chemical biology. 10, 8, p. 1939-51 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Systematic Mapping of Kinase Addiction Combinations in Breast Cancer Cells by Integrating Drug Sensitivity and Selectivity Profiles
Szwajda, A., Gautam, P., Karhinen, L., Jha, S. K., Saarela, J., Shakyawar, S., Turunen, L., Yadav, B., Tang, J., Wennerberg, Krister & Aittokallio, T., 20 Aug 2015, In: Chemistry & Biology. 22, 8, p. 1144-55 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Network pharmacology applications to map the unexplored target space and therapeutic potential of natural products
Kibble, M., Saarinen, N., Tang, J., Wennerberg, Krister, Mäkelä, S. & Aittokallio, T., Aug 2015, In: Natural Product Reports. 32, 8, p. 1249-66 18 p.Research output: Contribution to journal › Review › Research › peer-review
TIMMA-R: an R package for predicting synergistic multi-targeted drug combinations in cancer cell lines or patient-derived samples
He, L., Wennerberg, Krister, Aittokallio, T. & Tang, J., 1 Jun 2015, In: Bioinformatics (Online). 31, 11, p. 1866-8 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
Axitinib effectively inhibits BCR-ABL1(T315I) with a distinct binding conformation
Pemovska, T., Johnson, E., Kontro, M., Repasky, G. A., Chen, J., Wells, P., Cronin, C. N., McTigue, M., Kallioniemi, O., Porkka, K., Murray, B. W. & Wennerberg, Krister, 5 Mar 2015, In: Nature. 519, 7541, p. 102-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
Discovery of MINC1, a GTPase-activating protein small molecule inhibitor, targeting MgcRacGAP
van Adrichem, A. J., Fagerholm, A., Turunen, L., Lehto, A., Saarela, J., Koskinen, A., Repasky, G. A. & Wennerberg, Krister, 2015, In: Combinatorial Chemistry & High Throughput Screening. 18, 1, p. 3-17 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
KIFC1 is a novel potential therapeutic target for breast cancer
Li, Y., Lu, W., Chen, D., Boohaker, R. J., Zhai, L., Padmalayam, I., Wennerberg, Krister, Xu, B. & Zhang, W., 2015, In: Cancer Biology & Therapy. 16, 9, p. 1316-22 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Searching for Drug Synergy in Complex Dose-Response Landscapes Using an Interaction Potency Model
Yadav, B., Wennerberg, Krister, Aittokallio, T. & Tang, J., 2015, In: Computational and Structural Biotechnology Journal. 13, p. 504-13 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
What is synergy? The Saariselkä agreement revisited
Tang, J., Wennerberg, Krister & Aittokallio, T., 2015, In: Frontiers in Pharmacology. 6, p. 181Research output: Contribution to journal › Review › Research › peer-review
- 2014
Bioluminescent cell-based NAD(P)/NAD(P)H assays for rapid dinucleotide measurement and inhibitor screening
Vidugiriene, J., Leippe, D., Sobol, M., Vidugiris, G., Zhou, W., Meisenheimer, P., Gautam, P., Wennerberg, Krister & Cali, J. J., 17 Dec 2014, In: ASSAY and Drug Development Technologies. 12, 9-10, p. 514-26 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
A community effort to assess and improve drug sensitivity prediction algorithms
NCI DREAM Community, N. D. C., Dec 2014, In: Nature Biotechnology. 32, 12, p. 1202-12 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Identification of structural features in chemicals associated with cancer drug response: a systematic data-driven analysis
Khan, S. A., Virtanen, S., Kallioniemi, O. P., Wennerberg, Krister, Poso, A. & Kaski, S., 1 Sep 2014, In: Bioinformatics (Online). 30, 17, p. i497-504Research output: Contribution to journal › Journal article › Research › peer-review
Integrative and personalized QSAR analysis in cancer by kernelized Bayesian matrix factorization
Ammad-ud-din, M., Georgii, E., Gönen, M., Laitinen, T., Kallioniemi, O., Wennerberg, Krister, Poso, A. & Kaski, S., 25 Aug 2014, In: Journal of Chemical Information and Modeling. 54, 8, p. 2347-59 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Global Human-Kinase Screening Identifies Therapeutic Host Targets against Influenza
Atkins, C., Evans, C. W., Nordin, B., Patricelli, M. P., Reynolds, R., Wennerberg, Krister & Noah, J. W., Jul 2014, In: Journal of Biomolecular Screening. 19, 6, p. 936-46 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quantitative scoring of differential drug sensitivity for individually optimized anticancer therapies
Yadav, B., Pemovska, T., Szwajda, A., Kulesskiy, E., Kontro, M., Karjalainen, R., Majumder, M. M., Malani, D., Murumägi, A., Knowles, J., Porkka, K., Heckman, C., Kallioniemi, O., Wennerberg, Krister & Aittokallio, T., 5 Jun 2014, In: Scientific Reports. 4, p. 5193Research output: Contribution to journal › Journal article › Research › peer-review
The high throughput biomedicine unit at the institute for molecular medicine Finland: high throughput screening meets precision medicine
Pietiainen, V., Saarela, J., von Schantz, C., Turunen, L., Ostling, P. & Wennerberg, Krister, May 2014, In: Combinatorial Chemistry & High Throughput Screening. 17, 4, p. 377-86 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Making sense of large-scale kinase inhibitor bioactivity data sets: a comparative and integrative analysis
Tang, J., Szwajda, A., Shakyawar, S., Xu, T., Hintsanen, P., Wennerberg, Krister & Aittokallio, T., 24 Mar 2014, In: Journal of Chemical Information and Modeling. 54, 3, p. 735-43 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Utilization of in situ ELISA method for examining Trk receptor phosphorylation in cultured cells
Antila, H., Autio, H., Turunen, L., Harju, K., Tammela, P., Wennerberg, Krister, Yli-Kauhaluoma, J., Huttunen, H. J., Castrén, E. & Rantamäki, T., 30 Jan 2014, In: Journal of Neuroscience Methods. 222, p. 142-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Antifungal application of nonantifungal drugs
Stylianou, M., Kulesskiy, E., Lopes, J. P., Granlund, M., Wennerberg, Krister & Urban, C. F., 2014, In: Antimicrobial Agents and Chemotherapy. 58, 2, p. 1055-62 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 181406515
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Genomic Perturbations Reveal Distinct Regulatory Networks in Intrahepatic Cholangiocarcinoma
Research output: Contribution to journal › Journal article › Research › peer-review
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Targeting autophagy by small molecule inhibitors of vacuolar protein sorting 34 (Vps34) improves the sensitivity of breast cancer cells to Sunitinib
Research output: Contribution to journal › Journal article › Research › peer-review
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Drug Target Commons 2.0: a community platform for systematic analysis of drug-target interaction profiles
Research output: Contribution to journal › Journal article › Research › peer-review
Published