Krister Wennerberg

Krister Wennerberg

Professor

Member of:


    1. 2015
    2. MgcRacGAP inhibition stimulates JAK-dependent STAT3 activity

      van Adrichem, A. J. & Wennerberg, Krister, 21 Dec 2015, In: FEBS Letters. 589, 24 Pt B, p. 3859-65 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Impact of normalization methods on high-throughput screening data with high hit rates and drug testing with dose-response data

      Mpindi, J., Swapnil, P., Dmitrii, B., Jani, S., Saeed, K., Wennerberg, Krister, Aittokallio, T., Östling, P. & Kallioniemi, O., 1 Dec 2015, In: Bioinformatics (Online). 31, 23, p. 3815-21 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Relevance Rank Platform (RRP) for Functional Filtering of High Content Protein-Protein Interaction Data

      Pokharel, Y. R., Saarela, J., Szwajda, A., Rupp, C., Rokka, A., Lal Kumar Karna, S., Teittinen, K., Corthals, G., Kallioniemi, O., Wennerberg, Krister, Aittokallio, T. & Westermarck, J., Dec 2015, In: Molecular and Cellular Proteomics. 14, 12, p. 3274-83 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. From drug response profiling to target addiction scoring in cancer cell models

      Yadav, B., Gopalacharyulu, P., Pemovska, T., Khan, S. A., Szwajda, A., Tang, J., Wennerberg, Krister & Aittokallio, T., 1 Oct 2015, In: Disease models & mechanisms. 8, 10, p. 1255-64 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Bioluminescent, Nonlytic, Real-Time Cell Viability Assay and Use in Inhibitor Screening

      Duellman, S. J., Zhou, W., Meisenheimer, P., Vidugiris, G., Cali, J. J., Gautam, P., Wennerberg, Krister & Vidugiriene, J., Oct 2015, In: ASSAY and Drug Development Technologies. 13, 8, p. 456-65 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Rational Polypharmacology: Systematically Identifying and Engaging Multiple Drug Targets To Promote Axon Growth

      Al-Ali, H., Lee, D., Danzi, M. C., Nassif, H., Gautam, P., Wennerberg, Krister, Zuercher, B., Drewry, D. H., Lee, J. K., Lemmon, V. P. & Bixby, J. L., 21 Aug 2015, In: ACS chemical biology. 10, 8, p. 1939-51 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Systematic Mapping of Kinase Addiction Combinations in Breast Cancer Cells by Integrating Drug Sensitivity and Selectivity Profiles

      Szwajda, A., Gautam, P., Karhinen, L., Jha, S. K., Saarela, J., Shakyawar, S., Turunen, L., Yadav, B., Tang, J., Wennerberg, Krister & Aittokallio, T., 20 Aug 2015, In: Chemistry & Biology. 22, 8, p. 1144-55 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Network pharmacology applications to map the unexplored target space and therapeutic potential of natural products

      Kibble, M., Saarinen, N., Tang, J., Wennerberg, Krister, Mäkelä, S. & Aittokallio, T., Aug 2015, In: Natural Product Reports. 32, 8, p. 1249-66 18 p.

      Research output: Contribution to journalReviewResearchpeer-review

    10. TIMMA-R: an R package for predicting synergistic multi-targeted drug combinations in cancer cell lines or patient-derived samples

      He, L., Wennerberg, Krister, Aittokallio, T. & Tang, J., 1 Jun 2015, In: Bioinformatics (Online). 31, 11, p. 1866-8 3 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Axitinib effectively inhibits BCR-ABL1(T315I) with a distinct binding conformation

      Pemovska, T., Johnson, E., Kontro, M., Repasky, G. A., Chen, J., Wells, P., Cronin, C. N., McTigue, M., Kallioniemi, O., Porkka, K., Murray, B. W. & Wennerberg, Krister, 5 Mar 2015, In: Nature. 519, 7541, p. 102-5 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Discovery of MINC1, a GTPase-activating protein small molecule inhibitor, targeting MgcRacGAP

      van Adrichem, A. J., Fagerholm, A., Turunen, L., Lehto, A., Saarela, J., Koskinen, A., Repasky, G. A. & Wennerberg, Krister, 2015, In: Combinatorial Chemistry & High Throughput Screening. 18, 1, p. 3-17 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. KIFC1 is a novel potential therapeutic target for breast cancer

      Li, Y., Lu, W., Chen, D., Boohaker, R. J., Zhai, L., Padmalayam, I., Wennerberg, Krister, Xu, B. & Zhang, W., 2015, In: Cancer Biology & Therapy. 16, 9, p. 1316-22 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Searching for Drug Synergy in Complex Dose-Response Landscapes Using an Interaction Potency Model

      Yadav, B., Wennerberg, Krister, Aittokallio, T. & Tang, J., 2015, In: Computational and Structural Biotechnology Journal. 13, p. 504-13 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. What is synergy? The Saariselkä agreement revisited

      Tang, J., Wennerberg, Krister & Aittokallio, T., 2015, In: Frontiers in Pharmacology. 6, p. 181

      Research output: Contribution to journalReviewResearchpeer-review

    ID: 181406515