High-Content CRISPR Screens (HCCS)

BRIC’s Core Facility for high-content CRISPR screens (HCCS) offers assay automation and HT screening to BRIC, the University of Copenhagen and external researchers. The flexible and state-of-the-art screening platform opens possibilities for a wide variety of automated assays.

Customized screens can be performed in 384-well microtitre plate format utilizing immunofluorescence/fluorescent markers, luminescence or qPCR as read-out. To this end, several human siRNA libraries are readily available, alternative libraries including CRISPR and compound libraries can be facilitated through us.

We gladly help researchers with the initial assay setup, the automation thereof, screen performance, data and statistical analysis and finally candidate validation.

The HTCBS facility is part of DK-OPENSCREEN and EU-OPENSCREEN ERIC.