Modeling pathogenesis of primary liver cancer in lineage-specific mouse cell types
Research output: Contribution to journal › Journal article › Research › peer-review
Human primary liver cancer is classified into biologically distinct subgroups based on cellular origin. Liver cancer stem cells (CSCs) have been recently described. We investigated the ability of distinct lineages of hepatic cells to become liver CSCs and the phenotypic and genetic heterogeneity of primary liver cancer.
| Original language | English |
|---|---|
| Journal | Gastroenterology |
| Volume | 145 |
| Issue number | 1 |
| Pages (from-to) | 221-31 |
| Number of pages | 11 |
| ISSN | 0016-5085 |
| DOIs | |
| Publication status | Published - Jul 2013 |
| Externally published | Yes |
- Animals, Antigens, Polyomavirus Transforming, Cell Differentiation, Cell Lineage, Epithelial-Mesenchymal Transition, Genes, myc, Genes, ras, Hepatocytes, Liver Neoplasms, Mice, Mice, Inbred C57BL, Neoplastic Stem Cells
Research areas
ID: 97136348