Cord Herbert Brakebusch

Cord Herbert Brakebusch

ORCID: 0000-0002-9342-1634

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  1. Published

    p21-activated Kinase1(PAK1) can promote ERK activation in a kinase independent manner

    Wang, Z., Fu, M., Wang, L., Liu, J., Li, Y., Brakebusch, Cord Herbert & Mei, Q., 7 May 2013, In: Journal of Biological Chemistry.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    beta1-integrin-mediated signaling essentially contributes to cell survival after radiation-induced genotoxic injury.

    Cordes, N., Seidler, J., Durzok, R., Geinitz, H. & Brakebusch, Cord Herbert, 2006, In: Oncogene. 25, 9, p. 1378-90 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    beta1 integrins are not required for the maintenance of lymphocytes within intestinal epithelia.

    Marsal, J., Brakebusch, Cord Herbert, Bungartz, G., Fässler, R. & Agace, W. W., 2005, In: European Journal of Immunology. 35, 6, p. 1805-11 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    beta 1 integrin function in vivo: adhesion, migration and more.

    Brakebusch, Cord Herbert & Fässler, R., 2005, In: Cancer Metastasis Review. 24, 3, p. 403-11 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Up-Regulation of Activating Transcription Factor 3 in Human Fibroblasts Inhibits Melanoma Cell Growth and Migration Through a Paracrine Pathway

    Zu, T., Wen, J., Xu, L., Li, H., Mi, J., Brakebusch, Cord Herbert, Fisher, D. E. & Wu, X., 2020, In: Frontiers in Oncology. 10, 15 p., 624.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Two Transient Receptor Potential Channels at Focal Adhesions

    Mitsou, I., Carlson, C. R., Multhaupt, Hinke Arnolda B V H, Brakebusch, Cord Herbert & Couchman, John Robert, 2023, In: Journal of Histochemistry and Cytochemistry. 71, 9, p. 495-508 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Tumor necrosis factor (TNF) receptor shedding controls thresholds of innate immune activation that balance opposing TNF functions in infectious and inflammatory diseases.

    Xanthoulea, S., Pasparakis, M., Kousteni, S., Brakebusch, Cord Herbert, Wallach, D., Bauer, J., Lassmann, H. & Kollias, G., 2004, In: Journal of Experimental Medicine. 200, 3, p. 367-76 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Tie-1-directed expression of Cre recombinase in endothelial cells of embryoid bodies and transgenic mice.

    Gustafsson, E., Brakebusch, Cord Herbert, Hietanen, K. & Fässler, R., 2001, In: Journal of Cell Science. 114, Pt 4, p. 671-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Threonine 788 in integrin subunit beta1 regulates integrin activation.

    Nilsson, S., Kaniowska, D., Brakebusch, Cord Herbert, Fässler, R. & Johansson, S., 2006, In: Experimental Cell Research. 312, 6, p. 844-53 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    The small GTPase RhoA regulates the onset of myelination and myelin production during PNS development: [Meeting Abstract}

    Seixas, A., Morais, M., Pereira, J. A., Krause, S., Brakebusch, Cord Herbert, Suter, U. & Relvas, J. B., 2019, In: Glia. 67, S1, p. E473-E474 T12-052B.

    Research output: Contribution to journal › Conference abstract in journal › Research

  11. Published

    The small GTPase RhoA is required to maintain spinal cord neuroepithelium organization and the neural stem cell pool

    Herzog, D., Loetscher, P., van Hengel, J., Knüsel, S., Brakebusch, Cord Herbert, Taylor, V., Suter, U. & Relvas, J. B., 30 Mar 2011, In: Journal of Neuroscience. 31, 13, p. 5120-30 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    The small GTPase Rac1 is required for smooth muscle contraction

    Rahman, A., Davis, B., Lövdahl, C., Hanumaiah, V. T., Feil, R., Brakebusch, Cord Herbert & Arner, A., 1 Mar 2014, In: The Journal of Physiology. 592, 5, p. 915-26 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    The small G-proteins Rac1 and Cdc42 are essential for myoblast fusion in the mouse

    Vasyutina, E., Martarelli, B., Brakebusch, Cord Herbert, Wende, H. & Birchmeier, C., 2009, In: Proceedings of the National Academy of Science of the United States of America. 106, 22, p. 8935-40 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    The rho GTPase Rac1 is required for proliferation and survival of progenitors in the developing forebrain

    Leone, D. P., Srinivasan, K., Brakebusch, Cord Herbert & McConnell, S. K., 2010, In: Developmental Neurobiology. 70, 9, p. 659-78 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The integrin-actin connection, an eternal love affair.

    Brakebusch, Cord Herbert & Fässler, R., 2003, In: EMBO Journal. 22, 10, p. 2324-33 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    The fibronectin-binding integrins alpha5beta1 and alphavbeta3 differentially modulate RhoA-GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis.

    Danen, E. H. J., Sonneveld, P., Brakebusch, Cord Herbert, Fassler, R. & Sonnenberg, A., 2002, In: Journal of Cell Biology. 159, 6, p. 1071-86 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    The cysteine-rich domain of human ADAM 12 supports cell adhesion through syndecans and triggers signaling events that lead to beta1 integrin-dependent cell spreading.

    Iba, K., Albrechtsen, Reidar, Gilpin, B., Frohlich, C., Loechel, F., Zolkiewska, A., Ishiguro, K., Kojima, T., Liu, W., Langford, J. K., Sanderson, R. D., Brakebusch, Cord Herbert, Fässler, R. & Wewer, Ulla M., 2000, In: Journal of Cell Biology. 149, 5, p. 1143-56 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    The Small GTPase RHOA Links SLP65 Activation to PTEN Function in Pre B Cells and Is Essential for the Generation and Survival of Normal and Malignant B Cells

    Vadakumchery, A., Faraidun, H., Ayoubi, O. E., Outaleb, I., Schmid, V., Abdelrasoul, H., Amendt, T., Khadour, A., Setz, C., Göhring, K., Lodd, K., Hitzing, C., Alkhatib, A., Bilal, M., Benckendorff, J., Al Shugri, A. K., Brakebusch, C. H., Engels, N., Datta, M., Hobeika, E. & 2 others, Alsadeq, A. & Jumaa, H., 2022, In: Frontiers in Immunology. 13, 19 p., 842340.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface.

    Cappello, S., Attardo, A., Wu, X., Iwasato, T., Itohara, S., Wilsch-Bräuninger, M., Eilken, H. M., Rieger, M. A., Schroeder, T. T., Huttner, W. B., Brakebusch, Cord Herbert & Götz, M., 2006, In: Nature Neuroscience. 9, 9, p. 1099-107 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    The Interaction between Laminin-332 and α3β1 Integrin Determines Differentiation and Maintenance of CAFs, and Supports Invasion of Pancreatic Duct Adenocarcinoma Cells

    Cavaco, A. C. M., Rezaei, M., Caliandro, M. F., Lima, A. M., Stehling, M., Dhayat, S. A., Haier, J., Brakebusch, Cord Herbert & Eble, J. A., 2019, In: Cancers. 11, 1, p. 1-20 20 p., 14.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    The Essential Role of Rac1 Glucosylation in Clostridioides difficile Toxin B-Induced Arrest of G1-S Transition

    Petersen, L., Stroh, S., Schöttelndreier, D., Grassl, G. A., Rottner, K., Brakebusch, Cord Herbert, Fahrer, J. & Genth, H., 2022, In: Frontiers in Microbiology. 13, 11 p., 846215.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Syndecan-4 Protects the Heart From the Profibrotic Effects of Thrombin-Cleaved Osteopontin

    Herum, K. M., Romaine, A., Wang, A., Melleby, A. O., Strand, M. E., Pacheco, J., Braathen, B., Dunér, P., Tønnessen, T., Lunde, I. G., Sjaastad, I., Brakebusch, Cord Herbert, McCulloch, A. D., Gomez, M. F., Carlson, C. R. & Christensen, G., 2020, In: Journal of the American Heart Association. 9, 3, 31 p., e013518.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Suppression of tumor growth in vivo by local and systemic 90K level increase.

    Jallal, B., Powell, J., Zachwieja, J., Brakebusch, Cord Herbert, Germain, L., Jacobs, J., Iacobelli, S. & Ullrich, A., 1995, In: Cancer Research. 55, 15, p. 3223-7 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Structural requirements for inducible shedding of the p55 tumor necrosis factor receptor.

    Brakebusch, Cord Herbert, Varfolomeev, E. E., Batkin, M. & Wallach, D., 1994, In: Journal of Biological Chemistry. 269, 51, p. 32488-96 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Stage-specific functions of the small Rho GTPases Cdc42 and Rac1 for adult hippocampal neurogenesis

    Vadodaria, K. C., Brakebusch, Cord Herbert, Suter, U. & Jessberger, S., 16 Jan 2013, In: Journal of Neuroscience. 33, 3, p. 1179-89 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Stage-specific control of neural crest stem cell proliferation by the small rho GTPases Cdc42 and Rac1

    Fuchs, S., Herzog, D., Sumara, G., Büchmann-Møller, S., Civenni, G., Wu, X., Chrostek-Grashoff, A., Suter, U., Ricci, R., Relvas, J. B., Brakebusch, Cord Herbert & Sommer, L., 2009, In: Cell Stem Cell. 4, 3, p. 236-47 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors.

    Aderka, D., Engelmann, H., Maor, Y., Brakebusch, Cord Herbert & Wallach, D., 1992, In: Journal of Experimental Medicine. 175, 2, p. 323-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Specific deletion of Cdc42 does not affect meiotic spindle organization/migration and homologous chromosome segregation but disrupts polarity establishment and cytokinesis in mouse oocytes

    Wang, Z., Jiang, Z., Zhang, Q., Hu, M., Huang, L., Ou, X., Guo, L., Ouyang, Y., Hou, Y., Brakebusch, Cord Herbert, Schatten, H. & Sun, Q., Dec 2013, In: Molecular Biology of the Cell. 24, 24, p. 3832-41 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Soluble forms of tumor necrosis factor receptors (TNF-Rs). The cDNA for the type I TNF-R, cloned using amino acid sequence data of its soluble form, encodes both the cell surface and a soluble form of the receptor.

    Nophar, Y., Kemper, O., Brakebusch, Cord Herbert, Englemann, H., Zwang, R., Aderka, D., Holtmann, H. & Wallach, D., 1990, In: EMBO Journal. 9, 10, p. 3269-78 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Soluble and cell surface receptors for tumor necrosis factor.

    Wallach, D., Engelmann, H., Nophar, Y., Aderka, D., Kemper, O., Hornik, V., Holtmann, H. & Brakebusch, Cord Herbert, 1991, In: Agents and actions. Supplements. 35, p. 51-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Skin and hair follicle integrity is crucially dependent on beta 1 integrin expression on keratinocytes.

    Brakebusch, Cord Herbert, Grose, R., Quondamatteo, F., Ramirez, A., Jorcano, J. L., Pirro, A., Svensson, M., Herken, R., Sasaki, T., Timpl, R., Werner, S. & Fässler, R., 2000, In: EMBO Journal. 19, 15, p. 3990-4003 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Short arm region of laminin-5 gamma2 chain: structure, mechanism of processing and binding to heparin and proteins.

    Sasaki, T., Göhring, W., Mann, K., Brakebusch, Cord Herbert, Yamada, Y., Fässler, R. & Timpl, R., 2001, In: Journal of Molecular Biology. 314, 4, p. 751-63 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Sequence and chromosomal localization of the mouse brevican gene.

    Rauch, U., Meyer, H., Brakebusch, Cord Herbert, Seidenbecher, C., Gundelfinger, E. D., Beier, D. R. & Fässler, R., 1997, In: Genomics. 44, 1, p. 15-21 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Senescence regulation by nuclear N-WASP: a role in cancer?

    Li, H. & Brakebusch, Cord Herbert, Jul 2019, In: Oncoscience. 6, 7-8, p. 354-356 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Semaphorin-Plexin Signaling Controls Mitotic Spindle Orientation during Epithelial Morphogenesis and Repair

    Xia, J., Swiercz, J. M., Bañón-Rodríguez, I., Matković, I., Federico, G., Sun, T., Franz, T., Brakebusch, Cord Herbert, Kumanogoh, A., Friedel, R. H., Martín-Belmonte, F., Gröne, H., Offermanns, S. & Worzfeld, T., May 2015, In: Developmental Cell. 33, 3, p. 299-313 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Selective decrease in cell surface expression and mRNA level of the 55-kDa tumor necrosis factor receptor during differentiation of HL-60 cells into macrophage-like but not granulocyte-like cells.

    Winzen, R., Wallach, D., Engelmann, H., Nophar, Y., Brakebusch, Cord Herbert, Kemper, O., Resch, K. & Holtmann, H., 1992, In: Journal of Immunology. 148, 11, p. 3454-60 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Role of the beta1-integrin cytoplasmic tail in mediating invasin-promoted internalization of Yersinia.

    Gustavsson, A., Armulik, A., Brakebusch, Cord Herbert, Fässler, R., Johansson, S. & Fällman, M., 2002, In: Journal of Cell Science. 115, Pt 13, p. 2669-78 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Rhoh deficiency reduces peripheral T-cell function and attenuates allogenic transplant rejection

    Porubsky, S., Wang, S., Kiss, E., Dehmel, S., Bonrouhi, M., Dorn, T., Luckow, B., Brakebusch, Cord Herbert & Gröne, H., 1 Jan 2011, In: European Journal of Immunology. 41, 1, p. 76-88 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Rhodocytin (aggretin) activates platelets lacking alpha(2)beta(1) integrin, glycoprotein VI, and the ligand-binding domain of glycoprotein Ibalpha.

    Bergmeier, W., Bouvard, D., Eble, J. A., Mokhtari-Nejad, R., Schulte, V., Zirngibl, H., Brakebusch, Cord Herbert, Fässler, R. & Nieswandt, B., 2001, In: Journal of Biological Chemistry. 276, 27, p. 25121-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    RhoH is important for positive thymocyte selection and T-cell receptor signaling.

    Dorn, T., Kuhn, U., Bungartz, G., Stiller, S., Bauer, M., Ellwart, J., Peters, T., Scharffetter-Kochanek, K., Semmrich, M., Laschinger, M., Holzmann, B., Klinkert, W. E. F., Straten, P. T., Køllgaard, T., Sixt, M. & Brakebusch, Cord Herbert, 2006, In: Blood. 109, 6, p. 2346-55 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    RhoB promotesSalmonellasurvival by regulating autophagy

    Kirchenwitz, M., Halfen, J., Peinen, K. V., Prettin, S., Kollasser, J., Brakebusch, Cord Herbert, Rottner, K., Steffen, A. & Stradal, T. E. B., 2023, bioRxiv, 52 p.

    Research output: Working paper › Preprint

  42. Published

    RhoB promotes Salmonella survival by regulating autophagy

    Kirchenwitz, M., Halfen, J., von Peinen, K., Prettin, S., Kollasser, J., zur Lage, S., Blankenfeldt, W., Brakebusch, Cord Herbert, Rottner, K., Steffen, A. & Stradal, T. E. B., 2023, In: European Journal of Cell Biology. 102, 4, 17 p., 151358.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    RhoA/Cdc42 signaling drives cytoplasmic maturation but not endomitosis in megakaryocytes

    Heib, T., Hermanns, H. M., Manukjan, G., Englert, M., Kusch, C., Becker, I. C., Gerber, A., Wackerbarth, L. M., Burkard, P., Dandekar, T., Balkenhol, J., Jahn, D., Beck, S., Meub, M., Dütting, S., Stigloher, C., Sauer, M., Cherpokova, D., Schulze, H., Brakebusch, C. & 3 others, Nieswandt, B., Nagy, Z. & Pleines, I., 2021, In: Cell Reports. 35, 6, p. 109102 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells

    Ge, J., Burnier, L., Adamopoulou, M., Kwa, M. Q., Schaks, M., Rottner, K. & Brakebusch, Cord Herbert, 2018, In: The Journal of Biological Chemistry. 293, 24, p. 9358-9369 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes

    Jackson, B., Peyrollier, K., Pedersen, E., Basse, A., Karlsson, R., Wang, Z., Lefever, T., Ochsenbein, A. M., Schmidt, G., Aktories, K., Stanley, A., Quondamatteo, F., Ladwein, M., Rottner, K., van Hengel, J. & Brakebusch, Cord Herbert, 1 Mar 2011, In: Molecular Biology of the Cell. 22, 5, p. 593-605 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    RhoA in tyrosine hydroxylase neurons regulates food intake and body weight via altered sensitivity to peripheral hormones

    Skov, Louise Julie, Ratner, C., Hansen, Nikolaj Winther, Thompson, J. J., Egerod, Kristoffer Lihme, Burm, Hayley Beth, Dalbøge, L. S., Hedegaard, M. A., Brakebusch, Cord Herbert, Pers, Tune H, Perrier, Jean-Francois Marie & Holst, Birgitte, 2019, In: Journal of Neuroendocrinology. 31, 7, 13 p., UNSP e12761.

    Research output: Contribution to journal › Conference article › Research › peer-review

  47. Published

    RhoA drives actin compaction to restrict axon regeneration and astrocyte reactivity after CNS injury

    Stern, S., Hilton, B. J., Burnside, E. R., Dupraz, S., Handley, E. E., Gonyer, J. M., Brakebusch, Cord Herbert & Bradke, F., 2021, In: Neuron. 109, 21, p. 3436-3455 30 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    RhoA determines disease progression by controlling neutrophil motility and restricting hyperresponsiveness

    Jennings, R. T., Strengert, M., Hayes, P., El-Benna, J., Brakebusch, Cord Herbert, Kubica, M. & Knaus, U. G., 29 Apr 2014, In: Blood. 123, 23, p. 3635-45 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    RhoA Drives T-Cell Activation and Encephalitogenic Potential in an Animal Model of Multiple Sclerosis

    Manresa-Arraut, A., Johansen, F. F., Brakebusch, Cord Herbert, Issazadeh-Navikas, Shohreh & Hasseldam, Henrik, 2018, In: Frontiers in Immunology. 9, p. 1-14 14 p., 1235.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    RhoA Controls Retinoid Signaling by ROCK Dependent Regulation of Retinol Metabolism

    García-Mariscal, A., Peyrollier, K., Basse, A., Pedersen, E. D. K., Rühl, R., van Hengel, J. & Brakebusch, Cord Herbert, 2018, In: Small GTPases. 9, 5, p. 433–444

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    RhoA Controls Axon Extension Independent of Specification in the Developing Brain

    Dupraz, S., Hilton, B. J., Husch, A., Santos, T. E., Coles, C. H., Stern, S., Brakebusch, Cord Herbert & Bradke, F., 18 Nov 2019, In: Current biology : CB. 29, 22, p. 3874-3886 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Rho-family GTPase Cdc42 controls migration of Langerhans cells in vivo

    Luckashenak, N., Wähe, A., Breit, K., Brakebusch, Cord Herbert & Brocker, T., 1 Jan 2013, In: Journal of Immunology. 190, 1, p. 27-35 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Rho-A prenylation and signaling link epithelial homeostasis to intestinal inflammation

    López-Posadas, R., Becker, C., Günther, C., Tenzer, S., Amann, K., Billmeier, U., Atreya, R., Fiorino, G., Vetrano, S., Danese, S., Ekici, A. B., Wirtz, S., Thonn, V., Watson, A. J. M., Brakebusch, Cord Herbert, Bergö, M., Neurath, M. F. & Atreya, I., Feb 2016, In: The Journal of Clinical Investigation. 126, 2, p. 611-26 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Rho GTPases in cancer: friend or foe?

    Svensmark, J. H. & Brakebusch, Cord Herbert, 2019, In: Oncogene. 38, p. 7448-7456

    Research output: Contribution to journal › Review › Research › peer-review

  55. Published

    Rho GTPases and cancer

    Li, H., Peyrollier, K., Kilic, G. & Brakebusch, Cord Herbert, Mar 2014, In: BioFactors (Oxford, England). 40, 2, p. 226-35 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  56. Published

    Rho GTPases and Nox dependent ROS production in skin. Is there a connection?

    Stanley, A., Hynes, A., Brakebusch, Cord Herbert & Quondamatteo, F., Nov 2012, In: Histology and Histopathology. 27, 11, p. 1395-406 12 p.

    Research output: Contribution to journal › Review › Research › peer-review

  57. Accepted/In press

    Rho GTPase knockout induction in primary keratinocytes from adult mice

    Pedersen, E. D. K., Basse, A. L., Lefever, T., Peyrollier, K. C. & Brakebusch, Cord Herbert, 2011, (Accepted/In press) Methods in Rho GTPases. Rivero, F. (ed.). New York: Humana Press

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  58. Published

    Rho GTPase function in tumorigenesis

    Karlsson, R., Pedersen, E. D. K., Wang, Z. & Brakebusch, Cord Herbert, 2009, In: BBA General Subjects.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Rho GTPase function in development: How in vivo models change our view

    Pedersen, E. & Brakebusch, Cord Herbert, 29 May 2012, In: Experimental Cell Research. 318, 14, p. 1779-87 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Rho GTPase function in cell morphogenesis

    Pedersen, E. D. K. & Brakebusch, Cord Herbert, 2010, ENCYCLOPEDIA OF LIFE SCIENCES. Wiley

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  61. Published

    Rho GTPase Signaling in Health and Disease: A Complex Signaling Network

    Brakebusch, Cord Herbert, 2021, In: Cells. 10, 2, p. 1-3 401.

    Research output: Contribution to journal › Editorial › Research › peer-review

  62. Published

    Regulation of neural progenitor proliferation and survival by beta1 integrins.

    Leone, D. P., Relvas, J. B., Campos, L. S., Hemmi, S., Brakebusch, Cord Herbert, Fässler, R., Ffrench-Constant, C. & Suter, U., 2005, In: Journal of Cell Science. 118, Pt 12, p. 2589-99 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Redundant and nonredundant roles for Cdc42 and Rac1 in lymphomas developed in NPM-ALK transgenic mice

    Choudhari, R., Minero, V. G., Menotti, M., Pulito, R., Brakebusch, Cord Herbert, Compagno, M., Voena, C., Ambrogio, C. & Chiarle, R., 10 Mar 2016, In: Blood. 127, 10, p. 1297-306 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Rac1-dependent recruitment of PAK2 to G 2 phase centrosomes and their roles in the regulation of mitotic entry

    May, M., Schelle, I., Brakebusch, Cord Herbert, Rottner, K. & Genth, H., 19 May 2014, In: Cell Cycle. 13, 14, p. 2211-21 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Rac1 regulates neuronal polarization through the WAVE complex

    Tahirovic, S., Hellal, F., Neukirchen, D., Hindges, R., Garvalov, B. K., Flynn, K. C., Stradal, T. E., Chrostek-Grashoff, A., Brakebusch, Cord Herbert & Bradke, F., 2010, In: Journal of Neuroscience. 30, 20, p. 6930-43 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Rac1 promotes kidney collecting duct repair by mechanically coupling cell morphology to mitotic entry

    Bock, F., Dong, X., Li, S., Viquez, O. M., Sha, E., Tantengco, M., Hennen, E. M., Plosa, E., Ramezani, A., Brown, K. L., Whang, Y. M., Terker, A. S., Arroyo, J. P., Harrison, D. G., Fogo, A., Brakebusch, Cord Herbert, Pozzi, A. & Zent, R., 2024, In: Science Advances. 10, 6, 24 p., eadi7840.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Rac1 promotes kidney collecting duct integrity by limiting actomyosin activity

    Bock, F., Elias, B. C., Dong, X., Parekh, D. V., Mernaugh, G., Viquez, O. M., Hassan, A., Amara, V. R., Liu, J., Brown, K. L., Terker, A. S., Chiusa, M., Gewin, L. S., Fogo, A. B., Brakebusch, Cord Herbert, Pozzi, A. & Zent, R., 2021, In: Journal of Cell Biology. 220, 11, 28 p., e202103080.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Rac1 is essential for phospholipase C-gamma2 activation in platelets.

    Pleines, I., Elvers, M., Strehl, A., Pozgajova, M., Varga-Szabo, D., May, F., Chrostek-Grashoff, A., Brakebusch, Cord Herbert & Nieswandt, B., 2008, In: Pflügers Archiv: European Journal of Physiology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Rac1 is essential for basement membrane-dependent epiblast survival

    He, X., Liu, J., Qi, Y., Brakebusch, Cord Herbert, Chrostek-Grashoff, A., Edgar, D., Yurchenco, P. D., Corbett, S. A., Lowry, S. F., Graham, A. M., Han, Y. & Li, S., 2010, In: Molecular and Cellular Biology. 30, 14, p. 3569-81 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Rac1 is crucial for hair follicle integrity but is not essential for maintenance of the epidermis.

    Chrostek, A., Wu, X., Quondamatteo, F., Hu, R., Sanecka, A., Niemann, C., Langbein, L., Haase, I. & Brakebusch, Cord Herbert, 2006, In: Molecular and Cellular Biology. 26, 18, p. 6957-70 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Rac1 is crucial for Ras-dependent skin tumor formation by controlling Pak1-Mek-Erk hyperactivation and hyperproliferation in vivo

    Wang, Z., Pedersen, E. D. K., Basse, A., Lefever, T., Peyrollier, K., Kapoor, S., Mei, Q., Karlsson, R., Chrostek-Grashoff, A. & Brakebusch, Cord Herbert, 2010, In: Oncogene. 29, 23, p. 3362-73 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Rac function is crucial for cell migration but is not required for spreading and focal adhesion formation

    Steffen, A., Ladwein, M., Dimchev, G. A., Hein, A., Schwenkmezger, L., Arens, S., Ladwein, K. I., Margit Holleboom, J., Schur, F., Victor Small, J., Schwarz, J., Gerhard, R., Faix, J., Stradal, T. E. B., Brakebusch, Cord Herbert & Rottner, K., 15 Oct 2013, In: Journal of Cell Science. 126, Pt 20, p. 4572-88 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    RAC1 in keratinocytes regulates crosstalk to immune cells by Arp2/3-dependent control of STAT1

    Pedersen, E. D. K., Wang, Z., Stanley, A., Peyrollier, K., Rösner, L. M., Werfel, T., Quondamatteo, F. & Brakebusch, Cord Herbert, 15 Nov 2012, In: Journal of Cell Science. 125, Pt 22, p. 5379-90 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Proteomic analyses reveal divergent ubiquitylation site patterns in murinetissues

    Wagner, S. A., Beli, P., Weinert, B. T., Schölz, C. F., Kelstrup, C. D., Young, C., Nielsen, Michael Lund, Olsen, Jesper Velgaard, Brakebusch, Cord Herbert & Choudhary, Chunaram, 2012, In: Molecular & Cellular Proteomics.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions

    Akula, M. K., Ibrahim, M. X., Ivarsson, E. G., Khan, O. M., Kumar, I. T., Erlandsson, M., Karlsson, C., Xu, X., Brisslert, M., Brakebusch, Cord Herbert, Wang, D., Bokarewa, M., Sayin, V. I. & Bergo, M. O., 4 Sep 2019, In: Nature Communications. 10, 1, p. 1-13 13 p., 3975.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Podocyte-specific loss of cdc42 leads to congenital nephropathy

    Scott, R. P., Hawley, S. P., Ruston, J., Du, J., Brakebusch, Cord Herbert, Jones, N. & Pawson, T., 19 Apr 2012, In: Journal of the American Society of Nephrology. 23, 7, p. 1149-54 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Pigmentation defect due to the deficiency of Rac1 in differentiated parts of the hair follicle

    Behrundt, K., Brakebusch, Cord Herbert, Pofahl, R., Krieg, T. & Hasse, I., 2008, In: Journal of Investigative Dermatology. 128, Suppl. 1

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    PATHBIO: an international training program for precision mouse phenotyping

    Ruberte, J., Schofield, P. N., Brakebusch, Cord Herbert, Vogel, P., Herault, Y., Gracia, G., McKerlie, C., Hrabĕ de Angelis, M., Hagn, M. & Sundberg, J. P., 2020, In: Mammalian Genome. 31, p. 49-53

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Opposing roles for RhoH GTPase during T-cell migration and activation

    Baker, C. M., Comrie, W. A., Hyun, Y., Chung, H., Fedorchuk, C. A., Lim, K., Brakebusch, Cord Herbert, McGrath, J. L., Waugh, R. E., Meier-Schellersheim, M. & Kim, M., 26 Jun 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 26, p. 10474-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    None of the integrins known to be present on the mouse egg or to be ADAM receptors are essential for sperm-egg binding and fusion.

    He, Z., Brakebusch, Cord Herbert, Fässler, R., Kreidberg, J. A., Primakoff, P. & Myles, D. G., 2003, In: Developmental Biology. 254, 2, p. 226-37 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Neuronal Rho GTPase Rac1 elimination confers neuroprotection in a mouse model of permanent ischemic stroke

    Karabiyik, C., Fernandes, R., Figueiredo, F. R., Socodato, R., Brakebusch, Cord Herbert, Lambertsen, K. L., Relvas, J. B. & Santos, S. D., 2018, In: Brain Pathology. 28, 4, p. 569-580 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Neuronal Rac1 is required for learning-evoked neurogenesis

    Haditsch, U., Anderson, M. P., Freewoman, J., Cord, B., Babu, H., Brakebusch, Cord Herbert & Palmer, T. D., 24 Jul 2013, In: Journal of Neuroscience. 33, 30, p. 12229-41 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Neurocan is dispensable for brain development.

    Zhou, X. H., Brakebusch, Cord Herbert, Matthies, H., Oohashi, T., Hirsch, E., Moser, M., Krug, M., Seidenbecher, C. I., Boeckers, T. M., Rauch, U., Buettner, R., Gundelfinger, E. D. & Fässler, R., 2001, In: Molecular and Cellular Biology. 21, 17, p. 5970-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Negative regulation of p53-induced senescence by N-WASP is crucial for DMBA/TPA-induced skin tumor formation

    Li, H., Petersen, S., Garcia Mariscal, A. & Brakebusch, Cord Herbert, 1 May 2019, In: Cancer Research. 79, 9, p. 2167-2181 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    NADPH oxidase complex-derived reactive oxygen species, the actin cytoskeleton, and rho GTPases in cell migration

    Stanley, A., Thompson, K., Hynes, A., Brakebusch, Cord Herbert & Quondamatteo, F., 1 May 2014, In: Antioxidants & Redox Signaling. 20, 13, p. 2026-42 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    N-WASP is a novel regulator of hair-follicle cycling that controls antiproliferative TGF{beta} pathways

    Lefever, T., Pedersen, E., Basse, A., Paus, R., Quondamatteo, F., Stanley, A. C., Langbein, L., Wu, X., Wehland, J., Lommel, S. & Brakebusch, Cord Herbert, 2010, In: Journal of Cell Science. 123, Pt 1, p. 128-40 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Multiple integrin-ligand interactions synergize in shear-resistant platelet adhesion at sites of arterial injury in vivo.

    Grüner, S., Prostredna, M., Schulte, V., Krieg, T., Eckes, B., Brakebusch, Cord Herbert & Nieswandt, B., 2003, In: Blood. 102, 12, p. 4021-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Multiple alterations of platelet functions dominated by increased secretion in mice lacking Cdc42 in platelets

    Pleines, I., Eckly, A., Elvers, M., Hagedorn, I., Eliautou, S., Bender, M., Wu, X., Lanza, F., Gachet, C., Brakebusch, Cord Herbert & Nieswandt, B., 2010, In: Blood. 115, 16, p. 3364-73 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    Mouse macrophages completely lacking Rho (RhoA, RhoB and RhoC) have severe lamellipodial retraction defects, but robust chemotactic navigation and increased motility

    Koenigs, V., Jennings, R., Vogl, T., Horsthemke, M., Bachg, A. C., Xu, Y., Grobe, K., Brakebusch, Cord Herbert, Schwab, A., Baehler, M., Knaus, U. G. & Hanley, P. J., 31 Oct 2014, In: The Journal of Biological Chemistry. 289, 44, p. 30772-30784 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Mouse as a Model Organism: From Animals to Cells

    Brakebusch, Cord Herbert (ed.) & Pihlajaniemi, T. (ed.), 2011, Dordrecht: Springer. 165 p.

    Research output: Book/Report › Anthology › Research › peer-review

  91. Published

    Microglial Rac1 is essential for experience-dependent brain plasticity and cognitive performance

    Socodato, R., Almeida, T. O., Portugal, C. C., Santos, E. C. S., Tedim-Moreira, J., Galvão-Ferreira, J., Canedo, T., Baptista, F. I., Magalhães, A., Ambrósio, A. F., Brakebusch, Cord Herbert, Rubinstein, B., Moreira, I. S., Summavielle, T., Pinto, I. M. & Relvas, J. B., 2023, In: Cell Reports. 42, 12, 28 p., 113447.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Microglia Dysfunction Caused by the Loss of Rhoa Disrupts Neuronal Physiology and Leads to Neurodegeneration

    Socodato, R., Portugal, C. C., Canedo, T., Rodrigues, A., Almeida, T. O., Henriques, J. F., Vaz, S. H., Magalhães, J., Silva, C. M., Baptista, F. I., Alves, R. L., Coelho-Santos, V., Silva, A. P., Paes-de-Carvalho, R., Magalhães, A., Brakebusch, Cord Herbert, Sebastião, A. M., Summavielle, T., Ambrósio, A. F. & Relvas, J. B., 2020, In: Cell Reports. 31, 12, p. 1-29 107796.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Mice lacking desmocollin 1 show epidermal fragility accompanied by barrier defects and abnormal differentiation.

    Chidgey, M., Brakebusch, Cord Herbert, Gustafsson, E., Cruchley, A., Hail, C., Kirk, S., Merritt, A., North, A., Tselepis, C., Hewitt, J., Byrne, C., Fassler, R. & Garrod, D., 2001, In: Journal of Cell Biology. 155, 5, p. 821-32 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Megakaryocyte-specific RhoA deficiency causes macrothrombocytopenia and defective platelet activation in hemostasis and thrombosis

    Pleines, I., Hagedorn, I., Gupta, S., May, F., Chakarova, L., van Hengel, J., Offermanns, S., Krohne, G., Kleinschnitz, C., Brakebusch, Cord Herbert & Nieswandt, B., 1 Nov 2011, In: Blood. 119, 4, p. 1054-63 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Mechanisms controlling the level of receptors for tumor necrosis factor.

    Holtmann, H., Brakebusch, Cord Herbert, König, M., Klocke, R., Winzen, R., Resch, K. & Wallach, D., 1991, In: Agents and Actions. 32, 1-2, p. 106-8 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Maintaining resting cardiac fibroblasts in vitro by disrupting mechanotransduction

    Gilles, G., McCulloch, A. D., Brakebusch, Cord Herbert & Herum, K. M., 2020, In: PLoS ONE. 15, 10, p. 1-13 e0241390.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Mac-2 binding protein is a cell-adhesive protein of the extracellular matrix which self-assembles into ring-like structures and binds beta1 integrins, collagens and fibronectin.

    Sasaki, T., Brakebusch, Cord Herbert, Engel, J. & Timpl, R., 1998, In: EMBO Journal. 17, 6, p. 1606-13 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    MRCKα Is Dispensable for Breast Cancer Development in the MMTV-PyMT Model

    Kwa, M. Q., Brandao, R., Phung, T. H., Ge, J., Scieri, G. & Brakebusch, Cord Herbert, 2021, In: Cells. 10, 4, 942.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Loss of RhoA promotes skin tumor formation and invasion by upregulation of RhoB

    García-Mariscal, A., Li, H., Pedersen, E., Peyrollier, K., Ryan, K. M., Stanley, A., Quondamatteo, F. & Brakebusch, Cord Herbert, 15 Feb 2018, In: Oncogene. 37, 7, p. 847-860 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    Leukocyte extravasation as a target for anti-inflammatory therapy - Which molecule to choose? (vol 14, pg 70, 2005)

    Boehncke, W. H., Schon, M. P., Giromolomi, G., Griffiths, C., Bos, J. D., Thestrup-Pedersen, K., Cavani, A., Nestle, F., Bonish, B. K., Campbell, J. J., Brakebusch, Cord Herbert & Nickoloff, B., 2007, In: Experimental Dermatology. 16, 9, p. 778-778

    Research output: Contribution to journal › Journal article › Research › peer-review

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