Cord Herbert Brakebusch
Department of Biomedical Sciences
Blegdamsvej 3
2200 København N
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p21-activated Kinase1(PAK1) can promote ERK activation in a kinase independent manner
Wang, Z., Fu, M., Wang, L., Liu, J., Li, Y., Brakebusch, Cord Herbert & Mei, Q., 7 May 2013, In: Journal of Biological Chemistry.Research output: Contribution to journal › Journal article › Research › peer-review
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beta1-integrin-mediated signaling essentially contributes to cell survival after radiation-induced genotoxic injury.
Cordes, N., Seidler, J., Durzok, R., Geinitz, H. & Brakebusch, Cord Herbert, 2006, In: Oncogene. 25, 9, p. 1378-90 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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beta1 integrins are not required for the maintenance of lymphocytes within intestinal epithelia.
Marsal, J., Brakebusch, Cord Herbert, Bungartz, G., Fässler, R. & Agace, W. W., 2005, In: European Journal of Immunology. 35, 6, p. 1805-11 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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beta 1 integrin function in vivo: adhesion, migration and more.
Brakebusch, Cord Herbert & Fässler, R., 2005, In: Cancer Metastasis Review. 24, 3, p. 403-11 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Up-Regulation of Activating Transcription Factor 3 in Human Fibroblasts Inhibits Melanoma Cell Growth and Migration Through a Paracrine Pathway
Zu, T., Wen, J., Xu, L., Li, H., Mi, J., Brakebusch, Cord Herbert, Fisher, D. E. & Wu, X., 2020, In: Frontiers in Oncology. 10, 15 p., 624.Research output: Contribution to journal › Journal article › Research › peer-review
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Two Transient Receptor Potential Channels at Focal Adhesions
Mitsou, I., Carlson, C. R., Multhaupt, Hinke Arnolda B V H, Brakebusch, Cord Herbert & Couchman, John Robert, 2023, In: Journal of Histochemistry and Cytochemistry. 71, 9, p. 495-508 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Tumor necrosis factor (TNF) receptor shedding controls thresholds of innate immune activation that balance opposing TNF functions in infectious and inflammatory diseases.
Xanthoulea, S., Pasparakis, M., Kousteni, S., Brakebusch, Cord Herbert, Wallach, D., Bauer, J., Lassmann, H. & Kollias, G., 2004, In: Journal of Experimental Medicine. 200, 3, p. 367-76 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Tie-1-directed expression of Cre recombinase in endothelial cells of embryoid bodies and transgenic mice.
Gustafsson, E., Brakebusch, Cord Herbert, Hietanen, K. & Fässler, R., 2001, In: Journal of Cell Science. 114, Pt 4, p. 671-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Threonine 788 in integrin subunit beta1 regulates integrin activation.
Nilsson, S., Kaniowska, D., Brakebusch, Cord Herbert, Fässler, R. & Johansson, S., 2006, In: Experimental Cell Research. 312, 6, p. 844-53 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The small GTPase RhoA regulates the onset of myelination and myelin production during PNS development: [Meeting Abstract}
Seixas, A., Morais, M., Pereira, J. A., Krause, S., Brakebusch, Cord Herbert, Suter, U. & Relvas, J. B., 2019, In: Glia. 67, S1, p. E473-E474 T12-052B.Research output: Contribution to journal › Conference abstract in journal › Research
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The small GTPase RhoA is required to maintain spinal cord neuroepithelium organization and the neural stem cell pool
Herzog, D., Loetscher, P., van Hengel, J., Knüsel, S., Brakebusch, Cord Herbert, Taylor, V., Suter, U. & Relvas, J. B., 30 Mar 2011, In: Journal of Neuroscience. 31, 13, p. 5120-30 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The small GTPase Rac1 is required for smooth muscle contraction
Rahman, A., Davis, B., Lövdahl, C., Hanumaiah, V. T., Feil, R., Brakebusch, Cord Herbert & Arner, A., 1 Mar 2014, In: The Journal of Physiology. 592, 5, p. 915-26 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The small G-proteins Rac1 and Cdc42 are essential for myoblast fusion in the mouse
Vasyutina, E., Martarelli, B., Brakebusch, Cord Herbert, Wende, H. & Birchmeier, C., 2009, In: Proceedings of the National Academy of Science of the United States of America. 106, 22, p. 8935-40 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The rho GTPase Rac1 is required for proliferation and survival of progenitors in the developing forebrain
Leone, D. P., Srinivasan, K., Brakebusch, Cord Herbert & McConnell, S. K., 2010, In: Developmental Neurobiology. 70, 9, p. 659-78 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The integrin-actin connection, an eternal love affair.
Brakebusch, Cord Herbert & Fässler, R., 2003, In: EMBO Journal. 22, 10, p. 2324-33 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The fibronectin-binding integrins alpha5beta1 and alphavbeta3 differentially modulate RhoA-GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis.
Danen, E. H. J., Sonneveld, P., Brakebusch, Cord Herbert, Fassler, R. & Sonnenberg, A., 2002, In: Journal of Cell Biology. 159, 6, p. 1071-86 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The cysteine-rich domain of human ADAM 12 supports cell adhesion through syndecans and triggers signaling events that lead to beta1 integrin-dependent cell spreading.
Iba, K., Albrechtsen, Reidar, Gilpin, B., Frohlich, C., Loechel, F., Zolkiewska, A., Ishiguro, K., Kojima, T., Liu, W., Langford, J. K., Sanderson, R. D., Brakebusch, Cord Herbert, Fässler, R. & Wewer, Ulla M., 2000, In: Journal of Cell Biology. 149, 5, p. 1143-56 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Small GTPase RHOA Links SLP65 Activation to PTEN Function in Pre B Cells and Is Essential for the Generation and Survival of Normal and Malignant B Cells
Vadakumchery, A., Faraidun, H., Ayoubi, O. E., Outaleb, I., Schmid, V., Abdelrasoul, H., Amendt, T., Khadour, A., Setz, C., Göhring, K., Lodd, K., Hitzing, C., Alkhatib, A., Bilal, M., Benckendorff, J., Al Shugri, A. K., Brakebusch, C. H., Engels, N., Datta, M., Hobeika, E. & 2 others, , 2022, In: Frontiers in Immunology. 13, 19 p., 842340.Research output: Contribution to journal › Journal article › Research › peer-review
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The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface.
Cappello, S., Attardo, A., Wu, X., Iwasato, T., Itohara, S., Wilsch-Bräuninger, M., Eilken, H. M., Rieger, M. A., Schroeder, T. T., Huttner, W. B., Brakebusch, Cord Herbert & Götz, M., 2006, In: Nature Neuroscience. 9, 9, p. 1099-107 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Interaction between Laminin-332 and α3β1 Integrin Determines Differentiation and Maintenance of CAFs, and Supports Invasion of Pancreatic Duct Adenocarcinoma Cells
Cavaco, A. C. M., Rezaei, M., Caliandro, M. F., Lima, A. M., Stehling, M., Dhayat, S. A., Haier, J., Brakebusch, Cord Herbert & Eble, J. A., 2019, In: Cancers. 11, 1, p. 1-20 20 p., 14.Research output: Contribution to journal › Journal article › Research › peer-review
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The Essential Role of Rac1 Glucosylation in Clostridioides difficile Toxin B-Induced Arrest of G1-S Transition
Petersen, L., Stroh, S., Schöttelndreier, D., Grassl, G. A., Rottner, K., Brakebusch, Cord Herbert, Fahrer, J. & Genth, H., 2022, In: Frontiers in Microbiology. 13, 11 p., 846215.Research output: Contribution to journal › Journal article › Research › peer-review
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Syndecan-4 Protects the Heart From the Profibrotic Effects of Thrombin-Cleaved Osteopontin
Herum, K. M., Romaine, A., Wang, A., Melleby, A. O., Strand, M. E., Pacheco, J., Braathen, B., Dunér, P., Tønnessen, T., Lunde, I. G., Sjaastad, I., Brakebusch, Cord Herbert, McCulloch, A. D., Gomez, M. F., Carlson, C. R. & Christensen, G., 2020, In: Journal of the American Heart Association. 9, 3, 31 p., e013518.Research output: Contribution to journal › Journal article › Research › peer-review
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Suppression of tumor growth in vivo by local and systemic 90K level increase.
Jallal, B., Powell, J., Zachwieja, J., Brakebusch, Cord Herbert, Germain, L., Jacobs, J., Iacobelli, S. & Ullrich, A., 1995, In: Cancer Research. 55, 15, p. 3223-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structural requirements for inducible shedding of the p55 tumor necrosis factor receptor.
Brakebusch, Cord Herbert, Varfolomeev, E. E., Batkin, M. & Wallach, D., 1994, In: Journal of Biological Chemistry. 269, 51, p. 32488-96 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Stage-specific functions of the small Rho GTPases Cdc42 and Rac1 for adult hippocampal neurogenesis
Vadodaria, K. C., Brakebusch, Cord Herbert, Suter, U. & Jessberger, S., 16 Jan 2013, In: Journal of Neuroscience. 33, 3, p. 1179-89 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 5296
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Embryonic Stem Cell Culture Conditions Support Distinct States Associated with Different Developmental Stages and Potency
Research output: Contribution to journal › Journal article › Research › peer-review
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207
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Inhibiting PGGT1B Disrupts Function of RHOA, Resulting in T-cell Expression of Integrin α4β7 and Development of Colitis in Mice
Research output: Contribution to journal › Journal article › Research › peer-review
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198
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The Interaction between Laminin-332 and α3β1 Integrin Determines Differentiation and Maintenance of CAFs, and Supports Invasion of Pancreatic Duct Adenocarcinoma Cells
Research output: Contribution to journal › Journal article › Research › peer-review
Published