Cord Herbert Brakebusch

Cord Herbert Brakebusch

ORCID: 0000-0002-9342-1634

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151 - 200 out of 203Page size: 50
  1. 2005
  2. Published

    beta 1 integrin function in vivo: adhesion, migration and more.

    Brakebusch, Cord Herbert & Fässler, R., 2005, In: Cancer Metastasis Review. 24, 3, p. 403-11 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    beta1 integrins are not required for the maintenance of lymphocytes within intestinal epithelia.

    Marsal, J., Brakebusch, Cord Herbert, Bungartz, G., Fässler, R. & Agace, W. W., 2005, In: European Journal of Immunology. 35, 6, p. 1805-11 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. 2004
  5. Published

    Beta1 integrins activate a MAPK signalling pathway in neural stem cells that contributes to their maintenance.

    Campos, L. S., Leone, D. P., Relvas, J. B., Brakebusch, Cord Herbert, Fässler, R., Suter, U. & ffrench-Constant, C., 2004, In: Development. 131, 14, p. 3433-44 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Conditional beta1-integrin gene deletion in neural crest cells causes severe developmental alterations of the peripheral nervous system.

    Pietri, T., Eder, O., Breau, M. A., Topilko, P., Blanche, M., Brakebusch, Cord Herbert, Fässler, R., Thiery, J. & Dufour, S., 2004, In: Development. 131, 16, p. 3871-83 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Tumor necrosis factor (TNF) receptor shedding controls thresholds of innate immune activation that balance opposing TNF functions in infectious and inflammatory diseases.

    Xanthoulea, S., Pasparakis, M., Kousteni, S., Brakebusch, Cord Herbert, Wallach, D., Bauer, J., Lassmann, H. & Kollias, G., 2004, In: Journal of Experimental Medicine. 200, 3, p. 367-76 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. 2003
  9. Published

    Beta1 integrins regulate chondrocyte rotation, G1 progression, and cytokinesis.

    Aszodi, A., Hunziker, E. B., Brakebusch, Cord Herbert & Fässler, R., 2003, In: Genes & Development. 17, 19, p. 2465-79 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Complementary roles of glycoprotein VI and alpha2beta1 integrin in collagen-induced thrombus formation in flowing whole blood ex vivo.

    Kuijpers, M. J. E., Schulte, V., Bergmeier, W., Lindhout, T., Brakebusch, Cord Herbert, Offermanns, S., Fässler, R., Heemskerk, J. W. M. & Nieswandt, B., 2003, In: The FASEB Journal. 17, 6, p. 685-7 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Complementary signaling through flt3 and interleukin-7 receptor alpha is indispensable for fetal and adult B cell genesis.

    Sitnicka, E., Brakebusch, Cord Herbert, Martensson, I., Svensson, M., Agace, W. W., Sigvardsson, M., Buza-Vidas, N., Bryder, D., Cilio, C. M., Ahlenius, H., Maraskovsky, E., Peschon, J. J. & Jacobsen, S. E. W., 2003, In: Journal of Experimental Medicine. 198, 10, p. 1495-506 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Functional inactivation of a fraction of excitatory synapses in mice deficient for the active zone protein bassoon.

    Altrock, W. D., tom Dieck, S., Sokolov, M., Meyer, A. C., Sigler, A., Brakebusch, C., Fässler, R., Richter, K., Boeckers, T. M., Potschka, H., Brandt, C., Löscher, W., Grimberg, D., Dresbach, T., Hempelmann, A., Hassan, H., Balschun, D., Frey, J. U., Brandstätter, J. H., Garner, C. C. & 2 others, Rosenmund, C. & Gundelfinger, E. D., 2003, In: Neuron. 37, 5, p. 787-800 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Multiple integrin-ligand interactions synergize in shear-resistant platelet adhesion at sites of arterial injury in vivo.

    Grüner, S., Prostredna, M., Schulte, V., Krieg, T., Eckes, B., Brakebusch, Cord Herbert & Nieswandt, B., 2003, In: Blood. 102, 12, p. 4021-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    None of the integrins known to be present on the mouse egg or to be ADAM receptors are essential for sperm-egg binding and fusion.

    He, Z., Brakebusch, Cord Herbert, Fässler, R., Kreidberg, J. A., Primakoff, P. & Myles, D. G., 2003, In: Developmental Biology. 254, 2, p. 226-37 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The integrin-actin connection, an eternal love affair.

    Brakebusch, Cord Herbert & Fässler, R., 2003, In: EMBO Journal. 22, 10, p. 2324-33 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. 2002
  17. Published

    A crucial role of beta 1 integrins for keratinocyte migration in vitro and during cutaneous wound repair.

    Grose, R., Hutter, C., Bloch, W., Thorey, I., Watt, F. M., Fässler, R., Brakebusch, Cord Herbert & Werner, S., 2002, In: Development. 129, 9, p. 2303-15 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Beta1 integrin is not essential for hematopoiesis but is necessary for the T cell-dependent IgM antibody response.

    Brakebusch, Cord Herbert, Fillatreau, S., Potocnik, A. J., Bungartz, G., Wilhelm, P., Svensson, M., Kearney, P., Körner, H., Gray, D. & Fässler, R., 2002, In: Immunity. 16, 3, p. 465-77 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Brevican-deficient mice display impaired hippocampal CA1 long-term potentiation but show no obvious deficits in learning and memory.

    Brakebusch, Cord Herbert, Seidenbecher, C. I., Asztely, F., Rauch, U., Matthies, H., Meyer, H., Krug, M., Böckers, T. M., Zhou, X., Kreutz, M. R., Montag, D., Gundelfinger, E. D. & Fässler, R., 2002, In: Molecular and Cellular Biology. 22, 21, p. 7417-27 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Integrins in invasive growth.

    Brakebusch, Cord Herbert, Bouvard, D., Stanchi, F., Sakai, T. & Fässler, R., 2002, In: Journal of Clinical Investigation. 109, 8, p. 999-1006 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Role of the beta1-integrin cytoplasmic tail in mediating invasin-promoted internalization of Yersinia.

    Gustavsson, A., Armulik, A., Brakebusch, Cord Herbert, Fässler, R., Johansson, S. & Fällman, M., 2002, In: Journal of Cell Science. 115, Pt 13, p. 2669-78 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    The fibronectin-binding integrins alpha5beta1 and alphavbeta3 differentially modulate RhoA-GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis.

    Danen, E. H. J., Sonneveld, P., Brakebusch, Cord Herbert, Fassler, R. & Sonnenberg, A., 2002, In: Journal of Cell Biology. 159, 6, p. 1071-86 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. 2001
  24. Published

    Distinct roles for dystroglycan, beta1 integrin and perlecan in cell surface laminin organization.

    Henry, M. D., Satz, J. S., Brakebusch, Cord Herbert, Costell, M., Gustafsson, E., Fässler, R. & Campbell, K. P., 2001, In: Journal of Cell Science. 114, Pt 6, p. 1137-44 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Functional consequences of integrin gene mutations in mice.

    Bouvard, D., Brakebusch, Cord Herbert, Gustafsson, E., Aszódi, A., Bengtsson, T., Berna, A. & Fässler, R., 2001, In: Circulation Research. 89, 3, p. 211-23 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Glycoprotein VI but not alpha2beta1 integrin is essential for platelet interaction with collagen.

    Nieswandt, B., Brakebusch, Cord Herbert, Bergmeier, W., Schulte, V., Bouvard, D., Mokhtari-Nejad, R., Lindhout, T., Heemskerk, J. W., Zirngibl, H. & Fässler, R., 2001, In: EMBO Journal. 20, 9, p. 2120-30 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Mice lacking desmocollin 1 show epidermal fragility accompanied by barrier defects and abnormal differentiation.

    Chidgey, M., Brakebusch, Cord Herbert, Gustafsson, E., Cruchley, A., Hail, C., Kirk, S., Merritt, A., North, A., Tselepis, C., Hewitt, J., Byrne, C., Fassler, R. & Garrod, D., 2001, In: Journal of Cell Biology. 155, 5, p. 821-32 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Neurocan is dispensable for brain development.

    Zhou, X. H., Brakebusch, Cord Herbert, Matthies, H., Oohashi, T., Hirsch, E., Moser, M., Krug, M., Seidenbecher, C. I., Boeckers, T. M., Rauch, U., Buettner, R., Gundelfinger, E. D. & Fässler, R., 2001, In: Molecular and Cellular Biology. 21, 17, p. 5970-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Rhodocytin (aggretin) activates platelets lacking alpha(2)beta(1) integrin, glycoprotein VI, and the ligand-binding domain of glycoprotein Ibalpha.

    Bergmeier, W., Bouvard, D., Eble, J. A., Mokhtari-Nejad, R., Schulte, V., Zirngibl, H., Brakebusch, Cord Herbert, Fässler, R. & Nieswandt, B., 2001, In: Journal of Biological Chemistry. 276, 27, p. 25121-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Short arm region of laminin-5 gamma2 chain: structure, mechanism of processing and binding to heparin and proteins.

    Sasaki, T., Göhring, W., Mann, K., Brakebusch, Cord Herbert, Yamada, Y., Fässler, R. & Timpl, R., 2001, In: Journal of Molecular Biology. 314, 4, p. 751-63 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Tie-1-directed expression of Cre recombinase in endothelial cells of embryoid bodies and transgenic mice.

    Gustafsson, E., Brakebusch, Cord Herbert, Hietanen, K. & Fässler, R., 2001, In: Journal of Cell Science. 114, Pt 4, p. 671-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. 2000
  33. Published

    Discoidin domain receptor 1 is activated independently of beta(1) integrin.

    Vogel, W., Brakebusch, Cord Herbert, Fässler, R., Alves, F., Ruggiero, F. & Pawson, T., 2000, In: Journal of Biological Chemistry. 275, 8, p. 5779-84 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Fetal and adult hematopoietic stem cells require beta1 integrin function for colonizing fetal liver, spleen, and bone marrow.

    Potocnik, A. J., Brakebusch, Cord Herbert & Fässler, R., 2000, In: Immunity. 12, 6, p. 653-63 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Increased levels of apoptosis in the prefusion neural folds underlie the craniofacial disorder, Treacher Collins syndrome.

    Dixon, J., Brakebusch, Cord Herbert, Fässler, R. & Dixon, M. J., 2000, In: Human Molecular Genetics. 9, 10, p. 1473-80 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Skin and hair follicle integrity is crucially dependent on beta 1 integrin expression on keratinocytes.

    Brakebusch, Cord Herbert, Grose, R., Quondamatteo, F., Ramirez, A., Jorcano, J. L., Pirro, A., Svensson, M., Herken, R., Sasaki, T., Timpl, R., Werner, S. & Fässler, R., 2000, In: EMBO Journal. 19, 15, p. 3990-4003 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    The cysteine-rich domain of human ADAM 12 supports cell adhesion through syndecans and triggers signaling events that lead to beta1 integrin-dependent cell spreading.

    Iba, K., Albrechtsen, Reidar, Gilpin, B., Frohlich, C., Loechel, F., Zolkiewska, A., Ishiguro, K., Kojima, T., Liu, W., Langford, J. K., Sanderson, R. D., Brakebusch, Cord Herbert, Fässler, R. & Wewer, Ulla M., 2000, In: Journal of Cell Biology. 149, 5, p. 1143-56 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. 1999
  39. Published

    Beta1 integrin promotes but is not essential for metastasis of ras-myc transformed fibroblasts.

    Brakebusch, Cord Herbert, Wennerberg, K., Krell, H. W., Weidle, U. H., Sallmyr, A., Johansson, S. & Fässler, R., 1999, In: Oncogene. 18, 26, p. 3852-61 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Induction of cell scattering by expression of beta1 integrins in beta1-deficient epithelial cells requires activation of members of the rho family of GTPases and downregulation of cadherin and catenin function.

    Gimond, C., van Der Flier, A., van Delft, S., Brakebusch, Cord Herbert, Kuikman, I., Collard, J. G., Fässler, R. & Sonnenberg, A., 1999, In: Journal of Cell Biology. 147, 6, p. 1325-40 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Integrin gene targeting.

    Talts, J. F., Brakebusch, Cord Herbert & Fässler, R., 1999, In: Methods in Molecular Biology. 129, p. 153-87 34 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Isolation and functional characterization of the human 90K promoter.

    Brakebusch, Cord Herbert, Sures, I., Jallal, B., Mossie, K., Fusco, O., Iacobelli, S. & Ullrich, A., 1999, In: Genomics. 57, 2, p. 268-78 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. 1998
  44. Published

    90K (MAC-2 BP) gene expression in breast cancer and evidence for the production of 90K by peripheral-blood mononuclear cells.

    Fusco, O., Querzoli, P., Nenci, I., Natoli, C., Brakebusch, Cord Herbert, Ullrich, A. & Iacobelli, S., 1998, In: International Journal of Cancer. 79, 1, p. 23-6 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Differential effect on TCR:CD3 stimulation of a 90-kD glycoprotein (gp90/Mac-2BP), a member of the scavenger receptor cysteine-rich domain protein family.

    Silvestri, B., Calderazzo, F., Coppola, V., Rosato, A., Iacobelli, S., Natoli, C., Ullrich, A., Sures, I., Azam, M., Brakebusch, Cord Herbert, Chieco-Bianchi, L. & Amadori, A., 1998, In: Clinical and Experimental Immunology. 113, 3, p. 394-400 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Mac-2 binding protein is a cell-adhesive protein of the extracellular matrix which self-assembles into ring-like structures and binds beta1 integrins, collagens and fibronectin.

    Sasaki, T., Brakebusch, Cord Herbert, Engel, J. & Timpl, R., 1998, In: EMBO Journal. 17, 6, p. 1606-13 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. 1997
  48. Published

    Beta 1 integrin is essential for teratoma growth and angiogenesis.

    Bloch, W., Forsberg, E., Lentini, S., Brakebusch, Cord Herbert, Martin, K., Krell, H. W., Weidle, U. H., Addicks, K. & Fässler, R., 1997, In: Journal of Cell Biology. 139, 1, p. 265-78 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Expression of the 90K immunostimulator gene is controlled by a promoter with unique features.

    Brakebusch, Cord Herbert, Jallal, B., Fusco, O., Iacobelli, S. & Ullrich, A., 1997, In: Journal of Biological Chemistry. 272, 6, p. 3674-82 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Genetic analysis of beta1 integrin function: confirmed, new and revised roles for a crucial family of cell adhesion molecules.

    Brakebusch, Cord Herbert, Hirsch, E., Potocnik, A. & Fässler, R., 1997, In: Journal of Cell Science. 110 ( Pt 23), p. 2895-904 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Sequence and chromosomal localization of the mouse brevican gene.

    Rauch, U., Meyer, H., Brakebusch, Cord Herbert, Seidenbecher, C., Gundelfinger, E. D., Beier, D. R. & Fässler, R., 1997, In: Genomics. 44, 1, p. 15-21 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. 1995
  53. Published

    Functional discrepancies between tumor necrosis factor and lymphotoxin alpha explained by trimer stability and distinct receptor interactions.

    Schuchmann, M., Hess, S., Bufler, P., Brakebusch, Cord Herbert, Wallach, D., Porter, A., Riethmüller, G. & Engelmann, H., 1995, In: European Journal of Immunology. 25, 8, p. 2183-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Suppression of tumor growth in vivo by local and systemic 90K level increase.

    Jallal, B., Powell, J., Zachwieja, J., Brakebusch, Cord Herbert, Germain, L., Jacobs, J., Iacobelli, S. & Ullrich, A., 1995, In: Cancer Research. 55, 15, p. 3223-7 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. 1994
  56. Published

    Dual role of the p75 tumor necrosis factor (TNF) receptor in TNF cytotoxicity.

    Bigda, J., Beletsky, I., Brakebusch, Cord Herbert, Varfolomeev, Y., Engelmann, H., Bigda, J., Holtmann, H. & Wallach, D., 1994, In: Journal of Experimental Medicine. 180, 2, p. 445-60 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Structural requirements for inducible shedding of the p55 tumor necrosis factor receptor.

    Brakebusch, Cord Herbert, Varfolomeev, E. E., Batkin, M. & Wallach, D., 1994, In: Journal of Biological Chemistry. 269, 51, p. 32488-96 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. 1992
  59. Published

    Cytoplasmic truncation of the p55 tumour necrosis factor (TNF) receptor abolishes signalling, but not induced shedding of the receptor.

    Brakebusch, Cord Herbert, Nophar, Y., Kemper, O., Engelmann, H. & Wallach, D., 1992, In: EMBO Journal. 11, 3, p. 943-50 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Selective decrease in cell surface expression and mRNA level of the 55-kDa tumor necrosis factor receptor during differentiation of HL-60 cells into macrophage-like but not granulocyte-like cells.

    Winzen, R., Wallach, D., Engelmann, H., Nophar, Y., Brakebusch, Cord Herbert, Kemper, O., Resch, K. & Holtmann, H., 1992, In: Journal of Immunology. 148, 11, p. 3454-60 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors.

    Aderka, D., Engelmann, H., Maor, Y., Brakebusch, Cord Herbert & Wallach, D., 1992, In: Journal of Experimental Medicine. 175, 2, p. 323-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. 1991
  63. Published

    Mechanisms controlling the level of receptors for tumor necrosis factor.

    Holtmann, H., Brakebusch, Cord Herbert, König, M., Klocke, R., Winzen, R., Resch, K. & Wallach, D., 1991, In: Agents and Actions. 32, 1-2, p. 106-8 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 5296