Claus Storgaard Sørensen

Claus Storgaard Sørensen

Associate Professor, Professor

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    ORCID: 0000-0001-6022-9710

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    1. Published

      Germline RBBP8 variants associated with early-onset breast cancer compromise replication fork stability

      Zarrizi, R., Higgs, M. R., Voßgröne, Karolin, Rossing, M., Bertelsen, B., Bose, M., Kousholt, A. N., Rösner, Heike Ilona, Network, T. C., Ejlertsen, Bent Laursen, Stewart, G. S., Nielsen, Finn Cilius & Sørensen, Claus Storgaard, 3 Aug 2020, In: The Journal of Clinical Investigation. 130, 8, p. 4069-4080 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      SCFCyclin F-dependent degradation of CDC6 suppresses DNA re-replication

      Walter, D., Hoffmann, Saskia, Komseli, E., Rappsilber, J., Gorgoulis, V. & Sørensen, Claus Storgaard, 2016, In: Nature Communications. 7, 10 p., 10530.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      PALB2-mutated human mammary cells display a broad spectrum of morphological and functional abnormalities induced by increased TGFβ signaling

      Tuppurainen, H., Laurila, N., Nätynki, M., Eshraghi, L., Tervasmäki, A., Erichsen, L., Sørensen, Claus Storgaard, Pylkäs, K., Winqvist, R. & Peltoketo, H., 2024, In: Cellular and Molecular Life Sciences. 81, 21 p., 173.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair.

      Sørensen, Claus Storgaard, Hansen, L. T., Dziegielewski, J., Syljuåsen, R. G., Lundin, C., Bartek, J. & Helleday, T., 2005, In: Nature Cell Biology. 7, 2, p. 195-201 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      NEK11: linking CHK1 and CDC25A in DNA damage checkpoint signaling

      Sørensen, Claus Storgaard, Melixetian, M., Klein, D. K. & Helin, K., 2010, In: Cell Cycle. 9, 3, p. 450-5 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      ATR, Claspin and the Rad9-Rad1-Hus1 complex regulate Chk1 and Cdc25A in the absence of DNA damage.

      Sørensen, Claus Storgaard, Syljuåsen, R. G., Lukas, J. & Bartek, J., 2004, In: Cell Cycle. 3, 7, p. 941-5 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Hereditary risk of breast and ovarian cancer: BRCA1 and BRCA2

      Sørensen, Claus Storgaard, 1 Jan 2018, Encyclopedia of Cancer. Elsevier, p. 214-217 4 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    8. Published

      Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A.

      Sørensen, Claus Storgaard, Syljuåsen, R. G., Falck, J., Schroeder, T., Rönnstrand, L., Khanna, K. K., Zhou, B., Bartek, J. & Lukas, J., 2003, In: Cancer Cell. 3, 3, p. 247-58 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Safeguarding genome integrity: the checkpoint kinases ATR, CHK1 and WEE1 restrain CDK activity during normal DNA replication

      Sørensen, Claus Storgaard & Syljuåsen, R. G., 2012, In: Nucleic Acids Research. 40, 2, p. 477-86 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage.

      Syljuåsen, R. G., Sørensen, Claus Storgaard, Hansen, L. T., Fugger, K., Lundin, C., Johansson, F., Helleday, T., Sehested, M., Lukas, J. & Bartek, J., 2005, In: Molecular and Cellular Biology. 25, 9, p. 3553-62 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 10867