Claus Storgaard Sørensen
Associate Professor, Professor
Sørensen Group
Ole Maaløes Vej 5, 2200 København N.
Member of:
- 2018
- Published
Topokaryotyping demonstrates single cell variability and stress dependent variations in nuclear envelope associated domains
Jurisic, A., Robin, C., Tarlykov, P., Siggens, L., Schoell, B., Jauch, A., Ekwall, K., Sørensen, Claus Storgaard, Lipinski, M., Shoaib, Muhammad & Ogryzko, V., 2018, In: Nucleic Acids Research. 46, 22, p. 1-16 16 p., e135.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Chromatin dynamics in genome stability: Roles in suppressing endogenous DNA damage and facilitating DNA repair
Nair, Nidhi, Shoaib, Muhammad & Sørensen, Claus Storgaard, 10 Jul 2017, In: International Journal of Molecular Sciences. 18, 7, 21 p., 1486.Research output: Contribution to journal › Review › Research › peer-review
- Published
The caspase-activated DNase: apoptosis and beyond
Larsen, Brian Daniel & Sørensen, Claus Storgaard, Apr 2017, In: F E B S Journal. 284, 8, p. 1160-1170 11 p.Research output: Contribution to journal › Review › Research › peer-review
- 2016
- Published
Hereditary breast and ovarian cancer: new genes in confined pathways
Nielsen, Finn Cilius, Hansen, T. V. O. & Sørensen, Claus Storgaard, Sep 2016, In: Nature Reviews. Cancer. 16, 9, p. 599-612 14 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing
Galanos, P., Vougas, K., Walter, D., Polyzos, A., Maya-Mendoza, A., Haagensen, E. J., Kokkalis, A., Roumelioti, F-M., Gagos, S., Tzetis, M., Canovas, B., Igea, A., Ahuja, A. K., Zellweger, R., Havaki, S., Kanavakis, E., Kletsas, D., Roninson, I. B., Garbis, S. D., Lopes, M. & 7 others, , Jul 2016, In: Nature Cell Biology. 18, 7, p. 777-89 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DNA replication and cancer: From dysfunctional replication origin activities to therapeutic opportunities
Boyer, A., Walter, D. & Sørensen, Claus Storgaard, Jun 2016, In: Seminars in Cancer Biology. 37-38, p. 16-25 10 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
ATM/ATR-mediated phosphorylation of PALB2 promotes RAD51 function
Ahlskog, J. K., Larsen, Brian Daniel, Achanta, K. & Sørensen, Claus Storgaard, May 2016, In: E M B O Reports. 17, 5, p. 671-81 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The PCNA-associated protein PARI negatively regulates homologous recombination via the inhibition of DNA repair synthesis
Burkovics, P., Dome, L., Juhasz, S., Altmannova, V., Sebesta, M., Pacesa, M., Fugger, K., Sørensen, Claus Storgaard, Lee, M. Y. W. T., Haracska, L. & Krejci, L., 20 Apr 2016, In: Nucleic Acids Research. 44, 7, p. 3176-89 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SCFCyclin F-dependent degradation of CDC6 suppresses DNA re-replication
Walter, D., Hoffmann, Saskia, Komseli, E., Rappsilber, J., Gorgoulis, V. & Sørensen, Claus Storgaard, 2016, In: Nature Communications. 7, 10 p., 10530.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Epigenetic Deficiencies and Replicative Stress: Driving Cancer Cells to an Early Grave
Shoaib, Muhammad & Sørensen, Claus Storgaard, 9 Nov 2015, In: Cancer Cell. 28, 5, p. 545-547 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FBH1: a new checkpoint factor
Boyer, A. & Sørensen, Claus Storgaard, 14 Aug 2015, In: OncoTarget. 6, 23, p. 19354-19355 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Exploiting replicative stress to treat cancer
Dobbelstein, M. & Sørensen, Claus Storgaard, Jun 2015, In: Nature Reviews. Drug Discovery. 14, 6, p. 405-23 19 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
FBH1 Catalyzes Regression of Stalled Replication Forks
Fugger, K., Mistrik, M., Neelsen, K. J., Yao, Q., Zellweger, R., Kousholt, A. N., Haahr, Peter Thorlund, Chu, W. K., Bartek, J., Lopes, M., Hickson, Ian David & Sørensen, Claus Storgaard, 10 Mar 2015, In: Cell Reports.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cyclin F suppresses B-Myb activity to promote cell cycle checkpoint control
Klein, D. K., Hoffmann, Saskia, Ahlskog, J. K., O'Hanlon, K., Quaas, M., Larsen, Brian Daniel, Rolland, B., Rösner, Heike Ilona, Walter, D., Kousholt, A. N., Menzel, T., Lees, M., Johansen, Jens Vilstrup, Rappsilber, J., Engeland, K. & Sørensen, Claus Storgaard, 2015, In: Nature Communications. 6, p. 5800Research output: Contribution to journal › Journal article › Research › peer-review
- Published
miR-19, a component of the oncogenic miR-17∼92 cluster, targets the DNA-end resection factor CtIP
Hühn, D., Kousholt, A. N., Sørensen, Claus Storgaard & Sartori, A. A., 2015, In: Oncogene. 0, p. 3977-3984 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Damage-induced DNA replication stalling relies on MAPK-activated protein kinase 2 activity
Köpper, F., Bierwirth, C., Schön, M., Kunze, M., Elvers, I., Kranz, D., Saini, P., Menon, M. B., Walter, D., Sørensen, Claus Storgaard, Gaestel, M., Helleday, T., Schön, M. P. & Dobbelstein, M., 15 Oct 2013, In: PNAS Early Edition. 110, 42, p. 16856-61 6 p.Research output: Contribution to journal › Journal article › Research
- Published
Histone H4 Lysine 20 methylation: key player in epigenetic regulation of genomic integrity
Jørgensen, S., Schotta, G. & Sørensen, Claus Storgaard, 1 Mar 2013, In: Nucleic Acids Research. 41, 5, p. 2797-806 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FBH1 co-operates with MUS81 in inducing DNA double-strand breaks and cell death following replication stress
Fugger, K., Chu, W. K., Haahr, P., Kousholt, A. N., Beck, H., Payne, M. J., Hanada, K., Hickson, Ian David & Sørensen, Claus Storgaard, 2013, In: Nature Communications. 4, p. 1423Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
LEDGF (p75) promotes DNA-end resection and homologous recombination
Daugaard, M., Baude, A., Fugger, K., Povlsen, L. K., Beck, H., Sørensen, Claus Storgaard, Petersen, N. H. T., Sorensen, P. H. B., Lukas, Claudia, Bartek, J., Lukas, Jiri, Rohde, M. & Jaattela, Marja, Aug 2012, In: Nature Structural & Molecular Biology. 19, 8, p. 803-810 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pathways for genome integrity in G2 phase of the cell cycle
Kousholt, A. N., Menzel, T. & Sørensen, Claus Storgaard, 1 Jan 2012, In: Biomolecules. 2, 4, p. 579-607 29 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
CtIP-dependent DNA resection is required for DNA damage checkpoint maintenance but not initiation
Kousholt, A. N., Fugger, K., Hoffmann, S., Larsen, Brian Daniel, Menzel, T., Sartori, A. A. & Sørensen, Claus Storgaard, 2012, In: Journal of Cell Biology. 197, 7, p. 869-76 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cyclin-dependent kinase suppression by WEE1 kinase protects the genome through control of replication initiation and nucleotide consumption
Beck, H., Nähse-Kumpf, V., Larsen, Marie Sofie Yoo, O'Hanlon, K. A., Patzke, S., Holmberg, Christian, Mejlvang, J., Groth, Anja, Nielsen, Olaf, Syljuåsen, R. G. & Sørensen, Claus Storgaard, 2012, In: Molecular and Cellular Biology. 32, 20, p. 4226-4236 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Safeguarding genome integrity: the checkpoint kinases ATR, CHK1 and WEE1 restrain CDK activity during normal DNA replication
Sørensen, Claus Storgaard & Syljuåsen, R. G., 2012, In: Nucleic Acids Research. 40, 2, p. 477-86 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
SET8 is degraded via PCNA-coupled CRL4(CDT2) ubiquitylation in S phase and after UV irradiation
Jørgensen, S., Eskildsen, M., Fugger, K., Hansen, L., Larsen, Marie Sofie Yoo, Kousholt, A. N., Syljuåsen, R. G., Trelle, M. B., Jensen, O. N., Helin, K. & Sørensen, Claus Storgaard, 10 Jan 2011, In: Journal of Cell Biology. 192, 1, p. 43-54 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A genetic screen identifies BRCA2 and PALB2 as key regulators of G2 checkpoint maintenance
Menzel, T., Nähse-Kumpf, V., Kousholt, A. N., Klein, D. K., Lund-Andersen, C., Lees, M., Johansen, Jens Vilstrup, Syljuåsen, R. G. & Sørensen, Claus Storgaard, 1 Jan 2011, In: E M B O Reports. 12, 7, p. 705-12 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 10867
Most downloads
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338
downloads
Chromatin dynamics in genome stability: Roles in suppressing endogenous DNA damage and facilitating DNA repair
Research output: Contribution to journal › Review › Research › peer-review
Published -
244
downloads
Histone H4K20 methylation mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
175
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Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability
Research output: Contribution to journal › Journal article › Research › peer-review
Published