Colm O'Rourke

Colm O'Rourke

Assistant Professor


  1. 2024
  2. Published

    Molecular portraits of patients with intrahepatic cholangiocarcinoma who diverge as rapid progressors or long survivors on chemotherapy

    O'Rourke, C. J., Salati, M., Rae, C., Carpino, G., Leslie, H., Pea, A., Prete, M. G., Bonetti, L. R., Amato, F., Montal, R., Upstill-Goddard, R., Nixon, C., Sanchon-Sanchez, P., Kunderfranco, P., Sia, D., Gaudio, E., Overi, D., Cascinu, S., Hogdall, D., Pugh, S. & 15 others, Domingo, E., Primrose, J. N., Bridgewater, J., Spallanzani, A., Gelsomino, F., Llovet, J. M., Calvisi, D. F., Boulter, L., Caputo, F., Lleo, A., Jamieson, N. B., Luppi, G., Dominici, M., Andersen, Jesper Bøje & Braconi, C., 2024, In: Gut. 73, p. 496-508

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2023
  4. Published

    MicroRNA-27a-3p targets FoxO signalling to induce tumour-like phenotypes in bile duct cells

    Duwe, Lea, Munoz-Garrido, P., Lewinska, Monika, Lafuente Barquero, Juan Francisco, Satriano, L., Høgdall, Dan Taksony Solyom, Taranta, A., Nielsen, B. S., Ghazal, A., Matter, M. S., Banales, J. M., Aldana, Blanca, Gao, Y., Marquardt, J. U., Roberts, L. R., Oliveira, R. C., Koshiol, J., O'Rourke, Colm & Andersen, Jesper Bøje, 2023, In: Journal of Hepatology. 78, 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. E-pub ahead of print

    Immunogenomics of cholangiocarcinoma

    Gehl, Virag, O'Rourke, Colm & Andersen, Jesper Bøje, 2023, (E-pub ahead of print) In: Hepatology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Genetic and epigenetic analysis of hepatocellular adenomas with atypical morphological features

    Haefliger, S., Hench, J., O'Rourke, Colm, Meyer-Schaller, N., Uzun, S., Saldarriaga, J., Weber, A., Mazzucchelli, L., Jermann, P., Frank, S., Andersen, Jesper Bøje, Terracciano, L., Sempoux, C. & Matter, M. S., 2023, In: Histopathology. 82, 5, p. 722–730 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Liquid biopsy-based protein biomarkers for risk prediction, early diagnosis and prognostication of cholangiocarcinoma

    Lapitz, A., Azkargorta, M., Milkiewicz, P., Olaizola, P., Zhuravleva, E., Grimsrud, M. M., Schramm, C., Arbelaiz, A., O'Rourke, C. J., La Casta, A., Milkiewicz, M., Pastor, T., Vesterhus, M., Jimenez-Agüero, R., Dill, M. T., Lamarca, A., Valle, J. W., Macias, R. I. R., Izquierdo-Sanchez, L., Castaño, Y. P. & 15 others, Caballero-Camino, F. J., Riaño, I., Krawczyk, M., Ibarra, C., Bustamante, J., Nova-Camacho, L. M., Falcon-Perez, J. M., Elortza, F., Perugorria, M. J., Andersen, Jesper Bøje, Bujanda, L., Karlsen, T. H., Folseraas, T., Rodrigues, P. M. & Banales, J. M., 2023, In: Journal of Hepatology. 79, 1, p. 93-108

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    miR-21-5p promotes NASH-related hepatocarcinogenesis

    Rodrigues, P. M., Afonso, M. B., Simão, A. L., Islam, T., Gaspar, M. M., O'Rourke, Colm, Lewinska, Monika, Andersen, Jesper Bøje, Arretxe, E., Alonso, C., Santos-Laso, Á., Izquierdo-Sanchez, L., Jimenez-Agüero, R., Eizaguirre, E., Bujanda, L., Pareja, M. J., Prip-Buus, C., Banales, J. M., Rodrigues, C. M. P. & Castro, R. E., 2023, In: Liver International. 43, 10, p. 2256-2274 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    P-123 CD73high biliary tract cancer (BTC) is a molecularly defined subtype with distinct clinical implications

    Salati, M., Anna, B., O'Rourke, Colm, Piscopo, F., Evangelista, L., Pisapia, P., Riccò, B., Spallanzani, A., Gelsomino, F., Malapelle, U., Bonetti, L. R., Andersen, Jesper, Troncone, G., Dominici, M., Brunella, F. & Carotenuto, P., 2023, In: Annals of Oncology. 34, p. S58 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  10. 2022
  11. Published

    Molecular therapeutic targets for cholangiocarcinoma: Present challenges and future possibilities

    Høgdall, Dan Taksony Solyom, O'Rourke, Colm & Andersen, Jesper Bøje, 2022, Advances in Cancer Research. Academic Press, Vol. 156. p. 343-366 (Advances in Cancer Research).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  12. Published

    Whole blood microRNAs capture systemic reprogramming and have diagnostic potential in patients with biliary tract cancer

    Høgdall, Dan Taksony Solyom, O'Rourke, Colm, Larsen, F. O., Zarforoushan, S., Christensen, Troels Dreier, Ghazal, A., Boisen, M. K., Muñoz-Garrido, P., Johansen, Julia Sidenius & Andersen, Jesper Bøje, 2022, In: Journal of Hepatology. 77, p. 1047-1058 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Targeting NAE1-mediated protein hyper-NEDDylation halts cholangiocarcinogenesis and impacts on tumor-stroma crosstalk in experimental models

    Olaizola, P., Lee-Law, P. Y., Fernandez-Barrena, M. G., Alvarez, L., Cadamuro, M., Azkargorta, M., O'Rourke, C. J., Caballero-Camino, F. J., Olaizola, I., Macias, R. I. R., Marin, J. J. G., Serrano-Maciá, M., Martinez-Chantar, M. L., Avila, M. A., Aspichueta, P., Calvisi, D. F., Evert, M., Fabris, L., Castro, R. E., Elortza, F. & 5 others, Andersen, Jesper Bøje, Bujanda, L., Rodrigues, P. M., Perugorria, M. J. & Banales, J. M., 2022, In: Journal of Hepatology. 77, 1, p. 177-190

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 130666470