Colm O'Rourke

Colm O'Rourke

Assistant Professor


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  1. Published

    Epigenetic events involved in organic cation transporter 1-dependent impaired response of hepatocellular carcinoma to sorafenib

    Al-Abdulla, R., Lozano, E., Macias, R. I. R., Monte, M. J., Briz, O., O'Rourke, Colm, Serrano, M. A., Banales, J. M., Avila, M. A., Martinez-Chantar, M. L., Geier, A., Andersen, Jesper Bøje & Marin, J. J. G., 2019, In: British Journal of Pharmacology. 176, 6, p. 787-800

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Epigenetic modifications precede molecular alterations and drive human hepatocarcinogenesis

    Czauderna, C., Poplawski, A., O'Rourke, Colm, Castven, D., Pérez-Aguilar, B., Becker, D., Heilmann-Heimbach, S., Odenthal, M., Amer, W., Schmiel, M., Drebber, U., Binder, H., Ridder, D. A., Schindeldecker, M., Straub, B. K., Galle, P. R., Andersen, Jesper Bøje, Thorgeirsson, S. S., Park, Y. N. & Marquardt, J. U., 2021, In: JCI insight. 6, 17, 19 p., e146196.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    MicroRNA-27a-3p targets FoxO signalling to induce tumour-like phenotypes in bile duct cells

    Duwe, Lea, Munoz-Garrido, P., Lewinska, Monika, Lafuente Barquero, Juan Francisco, Satriano, L., Høgdall, Dan Taksony Solyom, Taranta, A., Nielsen, B. S., Ghazal, A., Matter, M. S., Banales, J. M., Aldana, Blanca, Gao, Y., Marquardt, J. U., Roberts, L. R., Oliveira, R. C., Koshiol, J., O'Rourke, Colm & Andersen, Jesper Bøje, 2023, In: Journal of Hepatology. 78, 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Differential effects of FXR or TGR5 activation in cholangiocarcinoma progression

    Erice, O., Labiano, I., Arbelaiz, A., Santos-Laso, A., Munoz-Garrido, P., Jimenez-Agüero, R., Olaizola, P., Caro-Maldonado, A., Martín-Martín, N., Carracedo, A., Lozano, E., Marin, J. J., O'Rourke, C. J., Andersen, J. B., Llop, J., Gómez-Vallejo, V., Padro, D., Martin, A., Marzioni, M., Adorini, L. & 4 others, Trauner, M., Bujanda, L., Perugorria, M. J. & Banales, J. M., Apr 2018, In: B B A - Reviews on Cancer. 1864, 4, Part B, p. 1335-1344

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    TREM-2 defends the liver against hepatocellular carcinoma through multifactorial protective mechanisms

    Esparza-Baquer, A., Labiano, I., Sharif, O., Agirre-Lizaso, A., Oakley, F., Rodrigues, P. M., Zhuravleva, E., O'Rourke, C. J., Hijona, E., Jimenez-Agüero, R., Riaño, I., Landa, A., La Casta, A., Zaki, M. Y. W., Munoz-Garrido, P., Azkargorta, M., Elortza, F., Vogel, A., Schabbauer, G., Aspichueta, P. & 6 others, Andersen, Jesper Bøje, Knapp, S., Mann, D. A., Bujanda, L., Banales, J. M. & Perugorria, M. J., 2020, In: Gut. 70, 7

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. E-pub ahead of print

    Immunogenomics of cholangiocarcinoma

    Gehl, Virag, O'Rourke, Colm & Andersen, Jesper Bøje, 2023, (E-pub ahead of print) In: Hepatology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    E2F1 and E2F2-mediated repression of CPT2 establishes a lipid-rich tumor-promoting environment

    Gonzalez-Romero, F., Mestre, D., Aurrekoetxea, I., O'Rourke, C. J., Andersen, J. B., Woodhoo, A., Tamayo-Caro, M., Varela-Rey, M., Palomo-Irigoyen, M., Gomez-Santos, B., de Urturi, D. S., Nuñez-García, M., García-Rodríguez, J. L., Fernandez-Ares, L., Buque, X., Iglesias-Ara, A., Bernales, I., de Juan, V. G., Delgado, T. C., Goikoetxea-Usandizaga, N. & 15 others, Lee, R., Bhanot, S., Delgado, I., Perugorria, M. J., Errazti, G., Mosteiro, L., Gaztambide, S., de la Piscina, I. M., Iruzubieta, P., Crespo, J., Banales, J. M., Martínez-Chantar, M. L., Castaño, L., Zubiaga, A. M. & Aspichueta, P., 2021, In: Cancer Research. 81, 11, p. 2874-2887 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Genetic and epigenetic analysis of hepatocellular adenomas with atypical morphological features

    Haefliger, S., Hench, J., O'Rourke, Colm, Meyer-Schaller, N., Uzun, S., Saldarriaga, J., Weber, A., Mazzucchelli, L., Jermann, P., Frank, S., Andersen, Jesper Bøje, Terracciano, L., Sempoux, C. & Matter, M. S., 2023, In: Histopathology. 82, 5, p. 722–730 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Molecular therapeutic targets for cholangiocarcinoma: Present challenges and future possibilities

    Høgdall, Dan Taksony Solyom, O'Rourke, Colm & Andersen, Jesper Bøje, 2022, Advances in Cancer Research. Academic Press, Vol. 156. p. 343-366 (Advances in Cancer Research).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  10. Published

    Serum IL6 as a Prognostic Biomarker and IL6R as a Therapeutic Target in Biliary Tract Cancers

    Høgdall, Dan Taksony Solyom, O'Rourke, Colm, Dehlendorff, C., Larsen, O. F., Jensen, L. H., Johansen, A. Z., Dang, H., Factor, V. M., Grunnet, M., Mau-Sørensen, M., Oliveira, D. V. N. P., Linnemann, D., Boisen, M. K., Wang, X. W., Johansen, Julia Sidenius & Andersen, Jesper Bøje, 2020, In: Clinical Cancer Research. 26, 21, 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 130666470