Colm O'Rourke

Colm O'Rourke

Assistant Professor


  1. 2016
  2. Published

    Molecular Pathogenesis and Current Therapy in Intrahepatic Cholangiocarcinoma

    Høgdall, Dan Taksony Solyom, O'Rourke, Colm, Taranta, A., NP Oliveira, D. & Andersen, Jesper Bøje, 2016, In: Digestive Diseases. 34, 4, p. 440-51 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  3. 2017
  4. Published

    SOX17 Regulates Cholangiocyte Differentiation and Acts as a Tumor Suppressor in Cholangiocarcinoma

    Merino-Azpitarte, M., Lozano, E., Perugorria, M. J., Esparza-Baquer, A., Erice, O., Santos-Laso, A., O'Rourke, C., Andersen, J. B., Jiménez-Agüero, R., Lacasta, A., D'Amato, M., Briz, O., Jalan-Sakrikar, N., Huebert, R. C., Thelen, K. M., Gradilone, S. A., Aransay, A. M., Lavín, J. L., Fernández-Barrena, M. G., Matheu, A. & 5 others, Marzioni, M., Gores, G. J., Bujanda, L., Marin, J. J. G. & Banales, J. M., 22 Feb 2017, In: Journal of Hepatology. 67, 1, p. 72-83 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2018
  6. Published

    A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily

    Cancer Genome Atlas Research Network, C. G. A. R. N., 2018, In: Cell Systems. 7, 4, p. 422-437.e1-e7 23 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Epigenome dysregulation in cholangiocarcinoma

    O'Rourke, Colm, Munoz-Garrido, P., Aguayo, E. L. & Andersen, Jesper Bøje, 2018, In: BBA Molecular Basis of Disease. 1864, 4, Part B, p. 1423-1434 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published

    Differential effects of FXR or TGR5 activation in cholangiocarcinoma progression

    Erice, O., Labiano, I., Arbelaiz, A., Santos-Laso, A., Munoz-Garrido, P., Jimenez-Agüero, R., Olaizola, P., Caro-Maldonado, A., Martín-Martín, N., Carracedo, A., Lozano, E., Marin, J. J., O'Rourke, C. J., Andersen, J. B., Llop, J., Gómez-Vallejo, V., Padro, D., Martin, A., Marzioni, M., Adorini, L. & 4 others, Trauner, M., Bujanda, L., Perugorria, M. J. & Banales, J. M., Apr 2018, In: B B A - Reviews on Cancer. 1864, 4, Part B, p. 1335-1344

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Genomic Perturbations Reveal Distinct Regulatory Networks in Intrahepatic Cholangiocarcinoma

    Nepal, C., O'Rourke, Colm, Oliveira, D. V., Taranta, A., Shema, S., Gautam, P., Calderaro, J., Barbour, A., Raggi, C., Wennerberg, Krister, Wang, X. W., Lautem, A., Roberts, L. R. & Andersen, Jesper Bøje, Sep 2018, In: Hepatology. 68, 3, p. 949-963 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2019
  11. Published

    Epigenetic events involved in organic cation transporter 1-dependent impaired response of hepatocellular carcinoma to sorafenib

    Al-Abdulla, R., Lozano, E., Macias, R. I. R., Monte, M. J., Briz, O., O'Rourke, Colm, Serrano, M. A., Banales, J. M., Avila, M. A., Martinez-Chantar, M. L., Geier, A., Andersen, Jesper Bøje & Marin, J. J. G., 2019, In: British Journal of Pharmacology. 176, 6, p. 787-800

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Epigenome Remodeling in Cholangiocarcinoma

    O'Rourke, Colm, Lafuente Barquero, Juan Francisco & Andersen, Jesper Bøje, 2019, In: Trends in Cancer. 5, 6, p. 335-350 16 p.

    Research output: Contribution to journalReviewResearchpeer-review

  13. Published

    Identification of a pan-gamma-secretase inhibitor response signature for notch-driven cholangiocarcinoma

    O'Rourke, Colm, Matter, M., Nepal, C., Ton, P., Factor, V. & Andersen, Jesper Bøje, 2019, In: Journal of Hepatology. 70, 1, p. e28

    Research output: Contribution to journalConference abstract in journalResearch

  14. Published

    Therapeutic Potential of Pharmacoepigenetics in Cholangiocarcinoma

    O'Rourke, Colm, Satriano, L., Oliveira, D. V. N. P., Munoz-Garrido, P. & Andersen, Jesper Bøje, 2019, Pharmacoepigenetics. Academic Press, p. 551-562 12 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

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ID: 130666470