Colm O'Rourke

Colm O'Rourke

Assistant Professor


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  1. Published

    A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily

    Cancer Genome Atlas Research Network, C. G. A. R. N., 2018, In: Cell Systems. 7, 4, p. 422-437.e1-e7 23 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Causes of hOCT1-dependent cholangiocarcinoma resistance to sorafenib and sensitization by tumor-selective gene therapy

    Lozano, E., Macias, R. I. R., Monte, M. J., Asensio, M., Del Carmen, S., Sanchez-Vicente, L., Alonso-Peña, M., Al-Abdulla, R., Munoz-Garrido, P., Satriano, L., O'Rourke, Colm, Banales, J. M., Avila, M. A., Martinez-Chantar, M. L., Andersen, Jesper Bøje, Briz, O. & Marin, J. J. G., Oct 2019, In: Hepatology. 70, 4, p. 1246-1261 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    DNA Methylation in Ovarian Tumors - a Comparison Between Fresh Tissue and FFPE Samples

    Oliveira, D. V. N. P., Hentze, J., O'Rourke, Colm, Andersen, Jesper Bøje, Høgdall, Claus Kim & Høgdall, Estrid Vilma Solyom, 2021, In: Reproductive Sciences. 28, 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Differential effects of FXR or TGR5 activation in cholangiocarcinoma progression

    Erice, O., Labiano, I., Arbelaiz, A., Santos-Laso, A., Munoz-Garrido, P., Jimenez-Agüero, R., Olaizola, P., Caro-Maldonado, A., Martín-Martín, N., Carracedo, A., Lozano, E., Marin, J. J., O'Rourke, C. J., Andersen, J. B., Llop, J., Gómez-Vallejo, V., Padro, D., Martin, A., Marzioni, M., Adorini, L. & 4 others, Trauner, M., Bujanda, L., Perugorria, M. J. & Banales, J. M., Apr 2018, In: B B A - Reviews on Cancer. 1864, 4, Part B, p. 1335-1344

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    E2F1 and E2F2-mediated repression of CPT2 establishes a lipid-rich tumor-promoting environment

    Gonzalez-Romero, F., Mestre, D., Aurrekoetxea, I., O'Rourke, C. J., Andersen, J. B., Woodhoo, A., Tamayo-Caro, M., Varela-Rey, M., Palomo-Irigoyen, M., Gomez-Santos, B., de Urturi, D. S., Nuñez-García, M., García-Rodríguez, J. L., Fernandez-Ares, L., Buque, X., Iglesias-Ara, A., Bernales, I., de Juan, V. G., Delgado, T. C., Goikoetxea-Usandizaga, N. & 15 others, Lee, R., Bhanot, S., Delgado, I., Perugorria, M. J., Errazti, G., Mosteiro, L., Gaztambide, S., de la Piscina, I. M., Iruzubieta, P., Crespo, J., Banales, J. M., Martínez-Chantar, M. L., Castaño, L., Zubiaga, A. M. & Aspichueta, P., 2021, In: Cancer Research. 81, 11, p. 2874-2887 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Epigenetic events involved in organic cation transporter 1-dependent impaired response of hepatocellular carcinoma to sorafenib

    Al-Abdulla, R., Lozano, E., Macias, R. I. R., Monte, M. J., Briz, O., O'Rourke, Colm, Serrano, M. A., Banales, J. M., Avila, M. A., Martinez-Chantar, M. L., Geier, A., Andersen, Jesper Bøje & Marin, J. J. G., 2019, In: British Journal of Pharmacology. 176, 6, p. 787-800

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Epigenetic modifications precede molecular alterations and drive human hepatocarcinogenesis

    Czauderna, C., Poplawski, A., O'Rourke, Colm, Castven, D., Pérez-Aguilar, B., Becker, D., Heilmann-Heimbach, S., Odenthal, M., Amer, W., Schmiel, M., Drebber, U., Binder, H., Ridder, D. A., Schindeldecker, M., Straub, B. K., Galle, P. R., Andersen, Jesper Bøje, Thorgeirsson, S. S., Park, Y. N. & Marquardt, J. U., 2021, In: JCI insight. 6, 17, 19 p., e146196.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Epigenome Remodeling in Cholangiocarcinoma

    O'Rourke, Colm, Lafuente Barquero, Juan Francisco & Andersen, Jesper Bøje, 2019, In: Trends in Cancer. 5, 6, p. 335-350 16 p.

    Research output: Contribution to journal › Review › Research › peer-review

  9. Published

    Epigenome dysregulation in cholangiocarcinoma

    O'Rourke, Colm, Munoz-Garrido, P., Aguayo, E. L. & Andersen, Jesper Bøje, 2018, In: BBA Molecular Basis of Disease. 1864, 4, Part B, p. 1423-1434 12 p.

    Research output: Contribution to journal › Review › Research › peer-review

  10. Published

    Genetic and epigenetic analysis of hepatocellular adenomas with atypical morphological features

    Haefliger, S., Hench, J., O'Rourke, Colm, Meyer-Schaller, N., Uzun, S., Saldarriaga, J., Weber, A., Mazzucchelli, L., Jermann, P., Frank, S., Andersen, Jesper Bøje, Terracciano, L., Sempoux, C. & Matter, M. S., 2023, In: Histopathology. 82, 5, p. 722–730 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 130666470