Colm O'Rourke

Colm O'Rourke

Assistant Professor


Publication year:
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11 - 20 out of 34Page size: 10
  1. 2022
  2. Published

    Targeting NAE1-mediated protein hyper-NEDDylation halts cholangiocarcinogenesis and impacts on tumor-stroma crosstalk in experimental models

    Olaizola, P., Lee-Law, P. Y., Fernandez-Barrena, M. G., Alvarez, L., Cadamuro, M., Azkargorta, M., O'Rourke, C. J., Caballero-Camino, F. J., Olaizola, I., Macias, R. I. R., Marin, J. J. G., Serrano-Maciá, M., Martinez-Chantar, M. L., Avila, M. A., Aspichueta, P., Calvisi, D. F., Evert, M., Fabris, L., Castro, R. E., Elortza, F. & 5 others, Andersen, Jesper Bøje, Bujanda, L., Rodrigues, P. M., Perugorria, M. J. & Banales, J. M., 2022, In: Journal of Hepatology. 77, 1, p. 177-190

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Whole blood microRNAs capture systemic reprogramming and have diagnostic potential in patients with biliary tract cancer

    Høgdall, Dan Taksony Solyom, O'Rourke, Colm, Larsen, F. O., Zarforoushan, S., Christensen, Troels Dreier, Ghazal, A., Boisen, M. K., Muñoz-Garrido, P., Johansen, Julia Sidenius & Andersen, Jesper Bøje, 2022, In: Journal of Hepatology. 77, p. 1047-1058 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. 2021
  5. Published

    DNA Methylation in Ovarian Tumors - a Comparison Between Fresh Tissue and FFPE Samples

    Oliveira, D. V. N. P., Hentze, J., O'Rourke, Colm, Andersen, Jesper Bøje, Høgdall, Claus Kim & Høgdall, Estrid Vilma Solyom, 2021, In: Reproductive Sciences. 28, 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    E2F1 and E2F2-mediated repression of CPT2 establishes a lipid-rich tumor-promoting environment

    Gonzalez-Romero, F., Mestre, D., Aurrekoetxea, I., O'Rourke, C. J., Andersen, J. B., Woodhoo, A., Tamayo-Caro, M., Varela-Rey, M., Palomo-Irigoyen, M., Gomez-Santos, B., de Urturi, D. S., Nuñez-García, M., García-Rodríguez, J. L., Fernandez-Ares, L., Buque, X., Iglesias-Ara, A., Bernales, I., de Juan, V. G., Delgado, T. C., Goikoetxea-Usandizaga, N. & 15 others, Lee, R., Bhanot, S., Delgado, I., Perugorria, M. J., Errazti, G., Mosteiro, L., Gaztambide, S., de la Piscina, I. M., Iruzubieta, P., Crespo, J., Banales, J. M., Martínez-Chantar, M. L., Castaño, L., Zubiaga, A. M. & Aspichueta, P., 2021, In: Cancer Research. 81, 11, p. 2874-2887 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Epigenetic modifications precede molecular alterations and drive human hepatocarcinogenesis

    Czauderna, C., Poplawski, A., O'Rourke, Colm, Castven, D., Pérez-Aguilar, B., Becker, D., Heilmann-Heimbach, S., Odenthal, M., Amer, W., Schmiel, M., Drebber, U., Binder, H., Ridder, D. A., Schindeldecker, M., Straub, B. K., Galle, P. R., Andersen, Jesper Bøje, Thorgeirsson, S. S., Park, Y. N. & Marquardt, J. U., 2021, In: JCI insight. 6, 17, 19 p., e146196.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Longitudinal analysis of individual cfDNA methylome patterns in metastatic prostate cancer

    Silva, R., Moran, B., Baird, A. M., O'Rourke, Colm, Finn, S. P., McDermott, R., Watson, W., Gallagher, W. M., Brennan, D. J. & Perry, A. S., 2021, In: Clinical Epigenetics. 13, 10 p., 168.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Molecular targets in cholangiocarcinoma

    O'Rourke, Colm, Munoz-Garrido, P. & Andersen, Jesper Bøje, 2021, In: Hepatology. 73, S1, p. 62-74

    Research output: Contribution to journal › Review › Research › peer-review

  10. Published

    Structural aberrations are associated with poor survival in patients with clonal cytopenia of undetermined significance

    Mikkelsen, Stine Ulrik, Safavi, S., Dimopoulos, K., O'Rourke, Colm, Andersen, M. K., Holm, M. S., Marcher, C. W., Andersen, Jesper Bøje, Hansen, Jakob Werner & Grønbæk, Kirsten, 2021, In: Haematologica. 106, 6

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  11. 2020
  12. Published

    Identification of a Pan-Gamma-Secretase Inhibitor Response Signature for Notch-Driven Cholangiocarcinoma

    O'Rourke, Colm, Matter, M. S., Nepal, C., Caetano-Oliveira, R., Ton, P. T., Factor, V. M. & Andersen, Jesper Bøje, Jan 2020, In: Hepatology. 71, 1, p. 196-213 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Integrative molecular characterization of gallbladder cancer reveals microenvironment-associated subtypes

    Nepal, C., Zhu, B., O'Rourke, C. J., Bhatt, D. K., Lee, D., Song, L., Wang, D., Van Dyke, A., Choo-Wosoba, H., Liu, Z., Hildesheim, A., Goldstein, A. M., Dean, M., LaFuente-Barquero, J., Lawrence, S., Mutreja, K., Olanich, M. E., Bermejo, J. L., Ferreccio, C., Roa, J. C. & 8 others, Rashid, A., Hsing, A. W., Gao, Y., Chanock, S. J., Araya, J. C., Andersen, Jesper Bøje, Koshiol, J. & CGR Exome Studies Group(,), C. E. S. G., 2020, In: Journal of Hepatology. 7, 5, p. 1132-1144

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 130666470