Colm O'Rourke

Colm O'Rourke

Assistant Professor


  1. 2020
  2. Published

    Patients with Cholangiocarcinoma Present Specific RNA Profiles in Serum and Urine Extracellular Vesicles Mirroring the Tumor Expression: Novel Liquid Biopsy Biomarkers for Disease Diagnosis

    Lapitz, A., Arbelaiz, A., O'Rourke, C. J., Lavin, J. L., Casta, A. L., Ibarra, C., Jimeno, J. P., Santos-Laso, A., Izquierdo-Sanchez, L., Krawczyk, M., Perugorria, M. J., Jimenez-Aguero, R., Sanchez-Campos, A., Riaño, I., Gónzalez, E., Lammert, F., Marzioni, M., Macias, R. I. R., Marin, J. J. G., Karlsen, T. H. & 6 others, Bujanda, L., Falcón-Pérez, J. M., Andersen, Jesper Bøje, Aransay, A. M., Rodrigues, P. M. & Banales, J. M., 2020, In: Cells. 9, 3, p. 1-33

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Serum IL6 as a Prognostic Biomarker and IL6R as a Therapeutic Target in Biliary Tract Cancers

    Høgdall, Dan Taksony Solyom, O'Rourke, Colm, Dehlendorff, C., Larsen, O. F., Jensen, L. H., Johansen, A. Z., Dang, H., Factor, V. M., Grunnet, M., Mau-Sørensen, M., Oliveira, D. V. N. P., Linnemann, D., Boisen, M. K., Wang, X. W., Johansen, Julia Sidenius & Andersen, Jesper Bøje, 2020, In: Clinical Cancer Research. 26, 21, 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    TREM-2 defends the liver against hepatocellular carcinoma through multifactorial protective mechanisms

    Esparza-Baquer, A., Labiano, I., Sharif, O., Agirre-Lizaso, A., Oakley, F., Rodrigues, P. M., Zhuravleva, E., O'Rourke, C. J., Hijona, E., Jimenez-Agüero, R., Riaño, I., Landa, A., La Casta, A., Zaki, M. Y. W., Munoz-Garrido, P., Azkargorta, M., Elortza, F., Vogel, A., Schabbauer, G., Aspichueta, P. & 6 others, Andersen, Jesper Bøje, Knapp, S., Mann, D. A., Bujanda, L., Banales, J. M. & Perugorria, M. J., 2020, In: Gut. 70, 7

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2019
  6. Published

    Causes of hOCT1-dependent cholangiocarcinoma resistance to sorafenib and sensitization by tumor-selective gene therapy

    Lozano, E., Macias, R. I. R., Monte, M. J., Asensio, M., Del Carmen, S., Sanchez-Vicente, L., Alonso-Peña, M., Al-Abdulla, R., Munoz-Garrido, P., Satriano, L., O'Rourke, Colm, Banales, J. M., Avila, M. A., Martinez-Chantar, M. L., Andersen, Jesper Bøje, Briz, O. & Marin, J. J. G., Oct 2019, In: Hepatology. 70, 4, p. 1246-1261 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Epigenetic events involved in organic cation transporter 1-dependent impaired response of hepatocellular carcinoma to sorafenib

    Al-Abdulla, R., Lozano, E., Macias, R. I. R., Monte, M. J., Briz, O., O'Rourke, Colm, Serrano, M. A., Banales, J. M., Avila, M. A., Martinez-Chantar, M. L., Geier, A., Andersen, Jesper Bøje & Marin, J. J. G., 2019, In: British Journal of Pharmacology. 176, 6, p. 787-800

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Epigenome Remodeling in Cholangiocarcinoma

    O'Rourke, Colm, Lafuente Barquero, Juan Francisco & Andersen, Jesper Bøje, 2019, In: Trends in Cancer. 5, 6, p. 335-350 16 p.

    Research output: Contribution to journalReviewResearchpeer-review

  9. Published

    Identification of a pan-gamma-secretase inhibitor response signature for notch-driven cholangiocarcinoma

    O'Rourke, Colm, Matter, M., Nepal, C., Ton, P., Factor, V. & Andersen, Jesper Bøje, 2019, In: Journal of Hepatology. 70, 1, p. e28

    Research output: Contribution to journalConference abstract in journalResearch

  10. Published

    Therapeutic Potential of Pharmacoepigenetics in Cholangiocarcinoma

    O'Rourke, Colm, Satriano, L., Oliveira, D. V. N. P., Munoz-Garrido, P. & Andersen, Jesper Bøje, 2019, Pharmacoepigenetics. Academic Press, p. 551-562 12 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  11. 2018
  12. Published

    Genomic Perturbations Reveal Distinct Regulatory Networks in Intrahepatic Cholangiocarcinoma

    Nepal, C., O'Rourke, Colm, Oliveira, D. V., Taranta, A., Shema, S., Gautam, P., Calderaro, J., Barbour, A., Raggi, C., Wennerberg, Krister, Wang, X. W., Lautem, A., Roberts, L. R. & Andersen, Jesper Bøje, Sep 2018, In: Hepatology. 68, 3, p. 949-963 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Differential effects of FXR or TGR5 activation in cholangiocarcinoma progression

    Erice, O., Labiano, I., Arbelaiz, A., Santos-Laso, A., Munoz-Garrido, P., Jimenez-Agüero, R., Olaizola, P., Caro-Maldonado, A., Martín-Martín, N., Carracedo, A., Lozano, E., Marin, J. J., O'Rourke, C. J., Andersen, J. B., Llop, J., Gómez-Vallejo, V., Padro, D., Martin, A., Marzioni, M., Adorini, L. & 4 others, Trauner, M., Bujanda, L., Perugorria, M. J. & Banales, J. M., Apr 2018, In: B B A - Reviews on Cancer. 1864, 4, Part B, p. 1335-1344

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 130666470