Proliferative activity in metastatic malignant melanoma: comparison of pre-treatment and post-treatment metastases.
Research output: Contribution to journal › Journal article › Research › peer-review
In this study, the proliferative activity of malignant melanoma metastases was assessed before and after isolated limb perfusion chemotherapy by quantitating AgNORs, mitoses and PCNA activity. No significant difference in either AgNOR count, mitotic activity or PCNA index was observed. We conclude that AgNOR count, mitotic activity and PCNA index were not significantly effected by isolated limb perfusion chemotherapy.
| Original language | English |
|---|---|
| Journal | Journal of Cutaneous Pathology |
| Volume | 22 |
| Issue number | 4 |
| Pages (from-to) | 354-8 |
| Number of pages | 4 |
| ISSN | 0303-6987 |
| Publication status | Published - 1995 |
| Externally published | Yes |
Bibliographical note
Keywords: Antineoplastic Agents; Cell Division; Extremities; Humans; Infusion Pumps, Implantable; Melanoma; Mitotic Index; Necrosis; Nucleolus Organizer Region; Postoperative Complications; Postoperative Period; Proliferating Cell Nuclear Antigen; Skin Neoplasms
ID: 5240632